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The map label for this gene is galE [H]

Identifier: 116626317

GI number: 116626317

Start: 9132405

End: 9133328

Strand: Direct

Name: galE [H]

Synonym: Acid_7277

Alternate gene names: 116626317

Gene position: 9132405-9133328 (Clockwise)

Preceding gene: 116626312

Following gene: 116626319

Centisome position: 91.64

GC content: 61.9

Gene sequence:

>924_bases
GTGCGAATGCTGCTCAATCAGGGACACGATGTCACGGTGGTGGACAACCTGTCGAAGGGCTATCGCCACAACGTGCCGGC
GGAGCGCCTGCACGAGATCGACCTGGCGGACACGCAGGCGATCGCAGCGCTGCTCCGTGAAAAGAAGTGCGAGGCGGTGA
TCCACTTCGCAGCGTTCATCGCGGTGGGCGAATCGATGCGCGAACCGGCGAAGTATTTCACGAATAATGTTTGCGGGTCG
CTCTCGCTGCTGGATGCGATGACGCAGGCGGGCGTGAAACACCTGGTGTTCTCGTCCACGGCCGCGGTCTACGGCGATGT
GAAGAAGTCTCCAATCACGGAGGATTTCCCGATTCAGGCGGTGAACCCGTACGGGGAATCGAAGGTGATGGTGGAGACGC
TGCTGGGTTGGTTCGACCAGATTCATCATCTGACGAGCGTGTGCCTGCGCTACTTCAACGCGTCGGGCTGCGACCCGGAG
GGCGGACTGGGCGAGGAGCACGAGCCGGAGACGCACCTGATTCCGCTGGTGCTGCGCGCGGTGCAGACGGGTAAGCCGAT
CACGGTTTTCGGCGGCGATTACCCGACACCGGATGGTACGTGCATCCGGGATTACATCCACGTGAACGATTTGGCGCAGG
CGCACATTCTGGCGGTGGAGTATCTCATCAAAGGGGGCGCGAGCGATCAGTTCAATGTTGGGACGGGGACGGGGCACAGC
GTGCTGGAGATGATCCACGCGGTGGAAGAGGTAACGGGGAAGAAGGTGCCCTATGTGGTCGGCGCTCGACGCGAGGGTGA
TCCGCCGAGTTTGGTGGCGAGTAGTAAGAAGCTGCGCGAGCGGTTGGGATGGGCGCCGCGCTACGAGGAGCTGAAGGTGA
TTGTGGAGCATGCGTGGAGGTTCGCGAACAAGCGAGCCGGCTGA

Upstream 100 bases:

>100_bases
GCCATGCTACTACAATCGAGGGAGCAACCCAGTAACTCCACAAATGACTTCACGAAAGATACTTGTTACCGGCGGCGCCG
GATATATCGGATCCCACACC

Downstream 100 bases:

>100_bases
AAGCCGGCTGCAGGCAGGATTGCCTGCCCCACAGTTACACGTACAACGGACGCTCCCTTACGGTCGCGGCTCTGATGCGA
GTCTTCGCGGGCTTGCGAGC

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MRMLLNQGHDVTVVDNLSKGYRHNVPAERLHEIDLADTQAIAALLREKKCEAVIHFAAFIAVGESMREPAKYFTNNVCGS
LSLLDAMTQAGVKHLVFSSTAAVYGDVKKSPITEDFPIQAVNPYGESKVMVETLLGWFDQIHHLTSVCLRYFNASGCDPE
GGLGEEHEPETHLIPLVLRAVQTGKPITVFGGDYPTPDGTCIRDYIHVNDLAQAHILAVEYLIKGGASDQFNVGTGTGHS
VLEMIHAVEEVTGKKVPYVVGARREGDPPSLVASSKKLRERLGWAPRYEELKVIVEHAWRFANKRAG

Sequences:

>Translated_307_residues
MRMLLNQGHDVTVVDNLSKGYRHNVPAERLHEIDLADTQAIAALLREKKCEAVIHFAAFIAVGESMREPAKYFTNNVCGS
LSLLDAMTQAGVKHLVFSSTAAVYGDVKKSPITEDFPIQAVNPYGESKVMVETLLGWFDQIHHLTSVCLRYFNASGCDPE
GGLGEEHEPETHLIPLVLRAVQTGKPITVFGGDYPTPDGTCIRDYIHVNDLAQAHILAVEYLIKGGASDQFNVGTGTGHS
VLEMIHAVEEVTGKKVPYVVGARREGDPPSLVASSKKLRERLGWAPRYEELKVIVEHAWRFANKRAG
>Mature_307_residues
MRMLLNQGHDVTVVDNLSKGYRHNVPAERLHEIDLADTQAIAALLREKKCEAVIHFAAFIAVGESMREPAKYFTNNVCGS
LSLLDAMTQAGVKHLVFSSTAAVYGDVKKSPITEDFPIQAVNPYGESKVMVETLLGWFDQIHHLTSVCLRYFNASGCDPE
GGLGEEHEPETHLIPLVLRAVQTGKPITVFGGDYPTPDGTCIRDYIHVNDLAQAHILAVEYLIKGGASDQFNVGTGTGHS
VLEMIHAVEEVTGKKVPYVVGARREGDPPSLVASSKKLRERLGWAPRYEELKVIVEHAWRFANKRAG

Specific function: Can have functions other than metabolism of galactose. It also could be involved in preparation of carbohydrate residues for incorporation into complex polymers, such as exopolysaccharides [H]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=319, Percent_Identity=38.5579937304075, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI56118217, Length=319, Percent_Identity=38.5579937304075, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI189083684, Length=319, Percent_Identity=38.5579937304075, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI42516563, Length=295, Percent_Identity=26.7796610169492, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI7657641, Length=263, Percent_Identity=25.0950570342205, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1786974, Length=313, Percent_Identity=39.297124600639, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI48994969, Length=324, Percent_Identity=25.6172839506173, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788353, Length=325, Percent_Identity=26.4615384615385, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788365, Length=279, Percent_Identity=23.6559139784946, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=324, Percent_Identity=34.2592592592593, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71982038, Length=326, Percent_Identity=33.7423312883436, Blast_Score=174, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17568069, Length=230, Percent_Identity=27.8260869565217, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=304, Percent_Identity=37.171052631579, Blast_Score=193, Evalue=2e-50,
Organism=Drosophila melanogaster, GI19923002, Length=321, Percent_Identity=36.1370716510903, Blast_Score=194, Evalue=9e-50,
Organism=Drosophila melanogaster, GI21356223, Length=298, Percent_Identity=25.1677852348993, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 33740; Mature: 33740

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMLLNQGHDVTVVDNLSKGYRHNVPAERLHEIDLADTQAIAALLREKKCEAVIHFAAFI
CCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AVGESMREPAKYFTNNVCGSLSLLDAMTQAGVKHLVFSSTAAVYGDVKKSPITEDFPIQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCE
VNPYGESKVMVETLLGWFDQIHHLTSVCLRYFNASGCDPEGGLGEEHEPETHLIPLVLRA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
VQTGKPITVFGGDYPTPDGTCIRDYIHVNDLAQAHILAVEYLIKGGASDQFNVGTGTGHS
HHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
VLEMIHAVEEVTGKKVPYVVGARREGDPPSLVASSKKLRERLGWAPRYEELKVIVEHAWR
HHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FANKRAG
HHHCCCC
>Mature Secondary Structure
MRMLLNQGHDVTVVDNLSKGYRHNVPAERLHEIDLADTQAIAALLREKKCEAVIHFAAFI
CCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AVGESMREPAKYFTNNVCGSLSLLDAMTQAGVKHLVFSSTAAVYGDVKKSPITEDFPIQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCE
VNPYGESKVMVETLLGWFDQIHHLTSVCLRYFNASGCDPEGGLGEEHEPETHLIPLVLRA
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
VQTGKPITVFGGDYPTPDGTCIRDYIHVNDLAQAHILAVEYLIKGGASDQFNVGTGTGHS
HHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
VLEMIHAVEEVTGKKVPYVVGARREGDPPSLVASSKKLRERLGWAPRYEELKVIVEHAWR
HHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FANKRAG
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788721 [H]