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The map label for this gene is arsR [C]

Identifier: 116626267

GI number: 116626267

Start: 9077372

End: 9077713

Strand: Direct

Name: arsR [C]

Synonym: Acid_7227

Alternate gene names: 116626267

Gene position: 9077372-9077713 (Clockwise)

Preceding gene: 116626266

Following gene: 116626268

Centisome position: 91.09

GC content: 62.87

Gene sequence:

>342_bases
ATGCCCGACGCGCTGCGCCGTTTTAAAGCCGAGATCTTTCAGGCACTCGCCCATCCGACCCGGATCGCCATCGTGGAAGC
GCTCCGCCATGGGGAACTGCCCGCCGGGAAACTGATCGAGCGCCTTGGCCTGGAGCAGGCCAACGCCTCCCAGCACTTGG
CTGTGCTGCGTTCCAAGCAGATTGTAGTCAACCGCAAGGATGGCAACCAGGTCTTCTATTCCCTGCGCAGCCCGCTGCTG
ATCGACGTGCTGGACATCATGCGCCGCTACTTTCAGGCGCAACTGGCGGAGACAATGGCCGCCCTTGGGGAGATGGAGCG
GGAGCAAGAGGTGACGCGGTGA

Upstream 100 bases:

>100_bases
TCGGAATGTGTGGATCCGCAGGCTGCAGGGTTACGATCAGCCTGAGCGGTAGCCTGGGCAAGCGCATGCATATATTCGAG
AATTCGAATATAATGAAGGC

Downstream 100 bases:

>100_bases
CCGCCGTTCCCGAAACTCCGCTGGATCACTGGATGCCCAAGCTGGTGCTTTGCCTGCGCCAGTACACCTGGCAGATCTTC
GTCAAGGATCTGATCGCCGG

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 112

Protein sequence:

>113_residues
MPDALRRFKAEIFQALAHPTRIAIVEALRHGELPAGKLIERLGLEQANASQHLAVLRSKQIVVNRKDGNQVFYSLRSPLL
IDVLDIMRRYFQAQLAETMAALGEMEREQEVTR

Sequences:

>Translated_113_residues
MPDALRRFKAEIFQALAHPTRIAIVEALRHGELPAGKLIERLGLEQANASQHLAVLRSKQIVVNRKDGNQVFYSLRSPLL
IDVLDIMRRYFQAQLAETMAALGEMEREQEVTR
>Mature_112_residues
PDALRRFKAEIFQALAHPTRIAIVEALRHGELPAGKLIERLGLEQANASQHLAVLRSKQIVVNRKDGNQVFYSLRSPLLI
DVLDIMRRYFQAQLAETMAALGEMEREQEVTR

Specific function: Transcriptional Repressor For The Arsefg Operon. Arse Is A Trans-Acting Regulatory Protein Which Controls Its Own Expression. The Repressive Effect Of Arse Is Alleviated By Oxyions Of +III Oxidation State Of Arsenic, Antimony, And Bismuth, As Well As Arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12879; Mature: 12748

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDALRRFKAEIFQALAHPTRIAIVEALRHGELPAGKLIERLGLEQANASQHLAVLRSKQ
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHH
IVVNRKDGNQVFYSLRSPLLIDVLDIMRRYFQAQLAETMAALGEMEREQEVTR
HEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PDALRRFKAEIFQALAHPTRIAIVEALRHGELPAGKLIERLGLEQANASQHLAVLRSKQ
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHH
IVVNRKDGNQVFYSLRSPLLIDVLDIMRRYFQAQLAETMAALGEMEREQEVTR
HEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]