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The map label for this gene is nodV [H]

Identifier: 116626238

GI number: 116626238

Start: 9040907

End: 9043189

Strand: Direct

Name: nodV [H]

Synonym: Acid_7198

Alternate gene names: 116626238

Gene position: 9040907-9043189 (Clockwise)

Preceding gene: 116626237

Following gene: 116626241

Centisome position: 90.72

GC content: 61.72

Gene sequence:

>2283_bases
ATGACTGTCACTGACGAAATGTATCGGCGGGTCGTGATGGCCGTGCCCGAAGGCATATGGGTCGTTGACCCGGAAGGCCG
CACGATCTTTAGCAATCAACGGATGGCTGAGATTCTCGGTGTCGCCTTCGAATCAATGCCCCAGCAGTCCTGTTTTACCT
GCGTCTACCCCGAGGACGCCGATTCCGCGCGGAGTAATTTCGCCCGCGCTCTCGCAGGCGATCGCCGGCCGTTCGATTTT
CGCCTCCAGCGCGCGGATGGCTCGCCAGTCTGGGTCAGCATCACCTGCATGCCCATGAACAATGACGACGGCGTCCCCTT
CGGACTGCTCGGCATGTTCTCCGAGATCACCGAGCGGAAGCTGGCCGTAGACGCCCTGCGCGCCAGTGAAGAACGCCTCT
GGGAAATCATCAACGTCGCCTCGGTAGGCGTGGCCCAAACCGACCTCACCGCCCGTCTGGAAATGGTGAACGACCGGTTT
TGCGCGATCTTCGGATATGCGCGTGAGGAACTGCTCGGCAAGAGTCTTCGCGAGCTCTCGCATCCCGATGACCTCCTTAA
CATCGTTGAACAGACGCGCCGTCTGCTCTCCGGCGAAATCCCGTACCTCTGCGTGGACAAACGCCATATCCGCAAGGACG
GCGCCATCATCTGGTCCAGAGTGCACAAATCCTGCATCAGAGACCTGGCGGGACAGCCCACCCACACCATTGTTGTGTTG
GAAGAGATTACCGAGGCCGTACTCGCCCAGGCCGCGCTGAAGGAGAGCGAGGAGCGGTTTCGGGCTATGGCGGACAGCGC
ACCCGTTTTGATTTCCTTGTGGGACACGGGCCTGAACCCTATTTTCTGTAGCAGCCACCTGCTGGCTTTCGCCGGCCGCA
CCGAAGAACAGCTGCGCACCGGCGGCTTCGAGGATCTAGTTCATCCGGATGACCTTGAACGGGTCGATGCCGCCGTTCGC
GCCGCGGTTCAGCGGCAAGGCGCCTTCGAGATCGAGGTCCGAATGCGCAGGGCCGACGGTGAATATCGGTCCATGTTGAC
CAATGGAACCCCGCGTTTCGCCGCCGGCACCTATGCCGGCTACGTCATGATCACCGTCGATATCACGGAGTTCAAGCGCA
AGCAGGAGTACCTGATGGCGATGCAAAAGCTGGAGAGTCTCGGCGTGCTGGCGGCCGGCATCGCACATGACTTCAACAAT
CTGCTAGGCGGCATCCTGGCCTCCGCGGAGCTCATTTCGGCAGGTGGCGAGCAGGGTGCGCCGCTCGACGAGGAATCGCT
GCTCAGGATCCGGACGGCGGCCATTCGGGGCGGAGAGATCGTGCGTCAGCTGATGGCCTACGGCGGCGAAGAGAGTCAGG
CATTCTCGTCCGTAGAGATTCCGCAACTCGTCAACGAGATGCTCGAGCTTCTGAAAATTTCGATTTCGAAACGCGCTGTG
CTCAACGTCGATTTCCCCGCTGGACTTCCCTCCGTCCGGGCCAACACCGCCCAGTTGCGGCAGGTAGTCCTCAACCTGAT
CGTCAACGCGTCGGAGGCCCTCGAAGATACGCAGGGAGTCATTGCCATCACCGCTGCCCGGGTTTCCGGCGATGATTACC
AGCCGGCGGTCCTCGCTTCCCAGGATTATGTGAGCCTGACGGTCAGTGATTCGGGCTGCGGCATGACGGAGGAAGTCCAG
GCCAGGATCTTCGATCCGTTCTTCACCAGTAAATTTGCCGGCCGCGGACTGGGACTTGCTTCCGTGCAGGGAATTATTCG
CAGTCACGGCGGCGCCATCCATGTTACCAGCGCTCCCGGCCGGGGGTCCCGGTTTGAGGTCCTCCTGCCTGTGGCCAGTG
AACCAGTGAGTGAGCCTGCGGCGCCGGCGGAACCCGGCGCATCCTCGGAAGGAGATCCCATGGCTGCGACCGTTCTCATT
GTGGAAGACGAAGAAGCGCTCCGCACCGCGGTGTCGAAAATGCTCCGGCTCAGGGGCTTTCGAGTGCTCGAAAGCGGCGA
TGGCGCGGATGCTCTCAACCTGTTGCGGCGGAACGCGCCACCGGTCGATGTGGTCCTGCTGGACTTGAACTTGCCCGGCG
CGTCCGGCCCCGAGGTTTTGGCTGAATTGCAGGCCATCCGGCCCGGCGCCAAGGTCATTCTCACCTCGGCATACAGCCGG
GAGCGGGTACAGGCCGGTTTAGGCGGCGAACTGAACTGGCCTTACATCCGTAAGCCGTATCAACTCGCCGAACTCACGGC
CCTGCTGCTTAGCATTTCTCGTGGCGCCGCCGGTGGCCAGTAG

Upstream 100 bases:

>100_bases
CTCGCAACGCCGCAAAGCCGCAAAGTATCGCCAAGAACGCCATCGATCGCCCATCCCCTGAACGACGGTGTTATGCTGTT
GCTTCCCACAGGGCCGCACC

Downstream 100 bases:

>100_bases
GCGAGGCGCGCCTTACAGGAGCTTTCGCAGCTTCAATTCAACGACAAACACGTCGTATCCCCGCTGAATCAGCAGGCGGC
ATTCGCGGCCTTCGCGCGCT

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 760; Mature: 759

Protein sequence:

>760_residues
MTVTDEMYRRVVMAVPEGIWVVDPEGRTIFSNQRMAEILGVAFESMPQQSCFTCVYPEDADSARSNFARALAGDRRPFDF
RLQRADGSPVWVSITCMPMNNDDGVPFGLLGMFSEITERKLAVDALRASEERLWEIINVASVGVAQTDLTARLEMVNDRF
CAIFGYAREELLGKSLRELSHPDDLLNIVEQTRRLLSGEIPYLCVDKRHIRKDGAIIWSRVHKSCIRDLAGQPTHTIVVL
EEITEAVLAQAALKESEERFRAMADSAPVLISLWDTGLNPIFCSSHLLAFAGRTEEQLRTGGFEDLVHPDDLERVDAAVR
AAVQRQGAFEIEVRMRRADGEYRSMLTNGTPRFAAGTYAGYVMITVDITEFKRKQEYLMAMQKLESLGVLAAGIAHDFNN
LLGGILASAELISAGGEQGAPLDEESLLRIRTAAIRGGEIVRQLMAYGGEESQAFSSVEIPQLVNEMLELLKISISKRAV
LNVDFPAGLPSVRANTAQLRQVVLNLIVNASEALEDTQGVIAITAARVSGDDYQPAVLASQDYVSLTVSDSGCGMTEEVQ
ARIFDPFFTSKFAGRGLGLASVQGIIRSHGGAIHVTSAPGRGSRFEVLLPVASEPVSEPAAPAEPGASSEGDPMAATVLI
VEDEEALRTAVSKMLRLRGFRVLESGDGADALNLLRRNAPPVDVVLLDLNLPGASGPEVLAELQAIRPGAKVILTSAYSR
ERVQAGLGGELNWPYIRKPYQLAELTALLLSISRGAAGGQ

Sequences:

>Translated_760_residues
MTVTDEMYRRVVMAVPEGIWVVDPEGRTIFSNQRMAEILGVAFESMPQQSCFTCVYPEDADSARSNFARALAGDRRPFDF
RLQRADGSPVWVSITCMPMNNDDGVPFGLLGMFSEITERKLAVDALRASEERLWEIINVASVGVAQTDLTARLEMVNDRF
CAIFGYAREELLGKSLRELSHPDDLLNIVEQTRRLLSGEIPYLCVDKRHIRKDGAIIWSRVHKSCIRDLAGQPTHTIVVL
EEITEAVLAQAALKESEERFRAMADSAPVLISLWDTGLNPIFCSSHLLAFAGRTEEQLRTGGFEDLVHPDDLERVDAAVR
AAVQRQGAFEIEVRMRRADGEYRSMLTNGTPRFAAGTYAGYVMITVDITEFKRKQEYLMAMQKLESLGVLAAGIAHDFNN
LLGGILASAELISAGGEQGAPLDEESLLRIRTAAIRGGEIVRQLMAYGGEESQAFSSVEIPQLVNEMLELLKISISKRAV
LNVDFPAGLPSVRANTAQLRQVVLNLIVNASEALEDTQGVIAITAARVSGDDYQPAVLASQDYVSLTVSDSGCGMTEEVQ
ARIFDPFFTSKFAGRGLGLASVQGIIRSHGGAIHVTSAPGRGSRFEVLLPVASEPVSEPAAPAEPGASSEGDPMAATVLI
VEDEEALRTAVSKMLRLRGFRVLESGDGADALNLLRRNAPPVDVVLLDLNLPGASGPEVLAELQAIRPGAKVILTSAYSR
ERVQAGLGGELNWPYIRKPYQLAELTALLLSISRGAAGGQ
>Mature_759_residues
TVTDEMYRRVVMAVPEGIWVVDPEGRTIFSNQRMAEILGVAFESMPQQSCFTCVYPEDADSARSNFARALAGDRRPFDFR
LQRADGSPVWVSITCMPMNNDDGVPFGLLGMFSEITERKLAVDALRASEERLWEIINVASVGVAQTDLTARLEMVNDRFC
AIFGYAREELLGKSLRELSHPDDLLNIVEQTRRLLSGEIPYLCVDKRHIRKDGAIIWSRVHKSCIRDLAGQPTHTIVVLE
EITEAVLAQAALKESEERFRAMADSAPVLISLWDTGLNPIFCSSHLLAFAGRTEEQLRTGGFEDLVHPDDLERVDAAVRA
AVQRQGAFEIEVRMRRADGEYRSMLTNGTPRFAAGTYAGYVMITVDITEFKRKQEYLMAMQKLESLGVLAAGIAHDFNNL
LGGILASAELISAGGEQGAPLDEESLLRIRTAAIRGGEIVRQLMAYGGEESQAFSSVEIPQLVNEMLELLKISISKRAVL
NVDFPAGLPSVRANTAQLRQVVLNLIVNASEALEDTQGVIAITAARVSGDDYQPAVLASQDYVSLTVSDSGCGMTEEVQA
RIFDPFFTSKFAGRGLGLASVQGIIRSHGGAIHVTSAPGRGSRFEVLLPVASEPVSEPAAPAEPGASSEGDPMAATVLIV
EDEEALRTAVSKMLRLRGFRVLESGDGADALNLLRRNAPPVDVVLLDLNLPGASGPEVLAELQAIRPGAKVILTSAYSRE
RVQAGLGGELNWPYIRKPYQLAELTALLLSISRGAAGGQ

Specific function: Member of the two-component regulatory system nodV/nodW probably involved in the regulation of the transcription of genes involved in the nodulation process. NodV may function as a membrane-associated protein kinase that phosphorylates nodW in response to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=257, Percent_Identity=31.1284046692607, Blast_Score=121, Evalue=2e-28,
Organism=Escherichia coli, GI1790436, Length=244, Percent_Identity=34.0163934426229, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1788381, Length=272, Percent_Identity=24.2647058823529, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI48994928, Length=535, Percent_Identity=23.9252336448598, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788713, Length=324, Percent_Identity=26.8518518518519, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790300, Length=261, Percent_Identity=27.2030651340996, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081816, Length=344, Percent_Identity=27.6162790697674, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI145693157, Length=274, Percent_Identity=26.6423357664234, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=26.0162601626016, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82566; Mature: 82435

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTDEMYRRVVMAVPEGIWVVDPEGRTIFSNQRMAEILGVAFESMPQQSCFTCVYPEDA
CCCCHHHHHHHHHHCCCCEEEECCCCCEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCC
DSARSNFARALAGDRRPFDFRLQRADGSPVWVSITCMPMNNDDGVPFGLLGMFSEITERK
CHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHH
LAVDALRASEERLWEIINVASVGVAQTDLTARLEMVNDRFCAIFGYAREELLGKSLRELS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
HPDDLLNIVEQTRRLLSGEIPYLCVDKRHIRKDGAIIWSRVHKSCIRDLAGQPTHTIVVL
CHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEH
EEITEAVLAQAALKESEERFRAMADSAPVLISLWDTGLNPIFCSSHLLAFAGRTEEQLRT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHC
GGFEDLVHPDDLERVDAAVRAAVQRQGAFEIEVRMRRADGEYRSMLTNGTPRFAAGTYAG
CCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHCCCCCCCCCCCCC
YVMITVDITEFKRKQEYLMAMQKLESLGVLAAGIAHDFNNLLGGILASAELISAGGEQGA
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PLDEESLLRIRTAAIRGGEIVRQLMAYGGEESQAFSSVEIPQLVNEMLELLKISISKRAV
CCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCEE
LNVDFPAGLPSVRANTAQLRQVVLNLIVNASEALEDTQGVIAITAARVSGDDYQPAVLAS
EEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCEEEEEEEEECCCCCCCEEEEC
QDYVSLTVSDSGCGMTEEVQARIFDPFFTSKFAGRGLGLASVQGIIRSHGGAIHVTSAPG
CCEEEEEEECCCCCCHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCC
RGSRFEVLLPVASEPVSEPAAPAEPGASSEGDPMAATVLIVEDEEALRTAVSKMLRLRGF
CCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCC
RVLESGDGADALNLLRRNAPPVDVVLLDLNLPGASGPEVLAELQAIRPGAKVILTSAYSR
EEEECCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECHHHH
ERVQAGLGGELNWPYIRKPYQLAELTALLLSISRGAAGGQ
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVTDEMYRRVVMAVPEGIWVVDPEGRTIFSNQRMAEILGVAFESMPQQSCFTCVYPEDA
CCCHHHHHHHHHHCCCCEEEECCCCCEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCC
DSARSNFARALAGDRRPFDFRLQRADGSPVWVSITCMPMNNDDGVPFGLLGMFSEITERK
CHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHH
LAVDALRASEERLWEIINVASVGVAQTDLTARLEMVNDRFCAIFGYAREELLGKSLRELS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
HPDDLLNIVEQTRRLLSGEIPYLCVDKRHIRKDGAIIWSRVHKSCIRDLAGQPTHTIVVL
CHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEH
EEITEAVLAQAALKESEERFRAMADSAPVLISLWDTGLNPIFCSSHLLAFAGRTEEQLRT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHC
GGFEDLVHPDDLERVDAAVRAAVQRQGAFEIEVRMRRADGEYRSMLTNGTPRFAAGTYAG
CCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHCCCCCCCCCCCCC
YVMITVDITEFKRKQEYLMAMQKLESLGVLAAGIAHDFNNLLGGILASAELISAGGEQGA
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PLDEESLLRIRTAAIRGGEIVRQLMAYGGEESQAFSSVEIPQLVNEMLELLKISISKRAV
CCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCEE
LNVDFPAGLPSVRANTAQLRQVVLNLIVNASEALEDTQGVIAITAARVSGDDYQPAVLAS
EEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCEEEEEEEEECCCCCCCEEEEC
QDYVSLTVSDSGCGMTEEVQARIFDPFFTSKFAGRGLGLASVQGIIRSHGGAIHVTSAPG
CCEEEEEEECCCCCCHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCC
RGSRFEVLLPVASEPVSEPAAPAEPGASSEGDPMAATVLIVEDEEALRTAVSKMLRLRGF
CCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCC
RVLESGDGADALNLLRRNAPPVDVVLLDLNLPGASGPEVLAELQAIRPGAKVILTSAYSR
EEEECCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEECHHHH
ERVQAGLGGELNWPYIRKPYQLAELTALLLSISRGAAGGQ
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2320582; 11157954; 12597275 [H]