Click here to switch to the map view.

The map label for this gene is 116626232

Identifier: 116626232

GI number: 116626232

Start: 9034204

End: 9034656

Strand: Direct

Name: 116626232

Synonym: Acid_7192

Alternate gene names: NA

Gene position: 9034204-9034656 (Clockwise)

Preceding gene: 116626227

Following gene: 116626233

Centisome position: 90.65

GC content: 59.82

Gene sequence:

>453_bases
ATGGGCACCGTCCTGATCAAGAAACCCGCCATCGACCCTCGATACGCTTTCTTCGAACTCGCGATCCGCGAGTCGAAGAT
CCACCGCCGCGGCGTCTACGCGCTGGAACGGATTCCGGCCCGCCGCAAAGTGATCGAGTACACCGGCCAGAAGATCAGCC
GCCGCGAGACCAAGCGGCGCGGCGATGGTGATATCACCTACCTCTTCACGCTCGACGATTACTGGACCCTCGATGGCGCC
TTCGGCGGCAGCGGCGCCGAAATCATCAACCATAGCTGCGAACCCAATCTCTACGCCTGGAATTTCAAGAAGCACATTCT
GTACATGAGCAAGCGCGTCATTCAGCGCGGCGAGGAACTGACAGTGGATTACCGCTTCTCCAAGGACGTGGAGCGCGTCC
CTTGCCTCTGCGGCGCCAAGACCTGCCGCGGCACCATCAATCTCTTGAAATAG

Upstream 100 bases:

>100_bases
CGGGCAAGAAATGTAATTTCACCCCTCAACCCGCAAGACCCGAACCAGAGTGCTTACTGGCACTGCCTGTGTACCTCGGC
TACAATCTGAGAACGTTCCC

Downstream 100 bases:

>100_bases
TGTGCGGAAGCTATCATAAAGAAAGTGCTCCCCGCAAAAACTTTCTTCACTGCTCTTGCCGCCGCCGGTGTGCTCGCAGC
GCAAGCCGTGCCATCGCTGG

Product: nuclear protein SET

Products: NA

Alternate protein names: SET Domain-Containing Protein; SET Domain Protein; Set Domain Protein; Histone-Lysine N-Methyltransferase; HistoNe-Lysine N-Methyltransferase H3 Lysine-4 Specific; Setd1a Protein; Nuclear Protein Set; Zinc Finger Protein

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MGTVLIKKPAIDPRYAFFELAIRESKIHRRGVYALERIPARRKVIEYTGQKISRRETKRRGDGDITYLFTLDDYWTLDGA
FGGSGAEIINHSCEPNLYAWNFKKHILYMSKRVIQRGEELTVDYRFSKDVERVPCLCGAKTCRGTINLLK

Sequences:

>Translated_150_residues
MGTVLIKKPAIDPRYAFFELAIRESKIHRRGVYALERIPARRKVIEYTGQKISRRETKRRGDGDITYLFTLDDYWTLDGA
FGGSGAEIINHSCEPNLYAWNFKKHILYMSKRVIQRGEELTVDYRFSKDVERVPCLCGAKTCRGTINLLK
>Mature_149_residues
GTVLIKKPAIDPRYAFFELAIRESKIHRRGVYALERIPARRKVIEYTGQKISRRETKRRGDGDITYLFTLDDYWTLDGAF
GGSGAEIINHSCEPNLYAWNFKKHILYMSKRVIQRGEELTVDYRFSKDVERVPCLCGAKTCRGTINLLK

Specific function: Unknown

COG id: COG2940

COG function: function code R; Proteins containing SET domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI56550039, Length=139, Percent_Identity=39.568345323741, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI210032580, Length=133, Percent_Identity=40.6015037593985, Blast_Score=97, Evalue=5e-21,
Organism=Homo sapiens, GI7662046, Length=139, Percent_Identity=39.568345323741, Blast_Score=97, Evalue=6e-21,
Organism=Homo sapiens, GI55741677, Length=139, Percent_Identity=38.8489208633094, Blast_Score=94, Evalue=5e-20,
Organism=Homo sapiens, GI91718902, Length=134, Percent_Identity=37.3134328358209, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI13375930, Length=147, Percent_Identity=37.4149659863946, Blast_Score=80, Evalue=6e-16,
Organism=Homo sapiens, GI301171597, Length=147, Percent_Identity=37.4149659863946, Blast_Score=80, Evalue=6e-16,
Organism=Homo sapiens, GI301171588, Length=147, Percent_Identity=37.4149659863946, Blast_Score=80, Evalue=6e-16,
Organism=Homo sapiens, GI4507321, Length=152, Percent_Identity=32.8947368421053, Blast_Score=74, Evalue=5e-14,
Organism=Homo sapiens, GI301171605, Length=131, Percent_Identity=37.4045801526718, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI301171613, Length=132, Percent_Identity=37.1212121212121, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI148762969, Length=134, Percent_Identity=35.8208955223881, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17552320, Length=134, Percent_Identity=42.5373134328358, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17552318, Length=134, Percent_Identity=42.5373134328358, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17552316, Length=134, Percent_Identity=42.5373134328358, Blast_Score=102, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI193210440, Length=137, Percent_Identity=33.5766423357664, Blast_Score=77, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI193202392, Length=133, Percent_Identity=31.5789473684211, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25141373, Length=133, Percent_Identity=31.5789473684211, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71988186, Length=125, Percent_Identity=32.8, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71993684, Length=128, Percent_Identity=33.59375, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321911, Length=136, Percent_Identity=39.7058823529412, Blast_Score=91, Evalue=1e-19,
Organism=Drosophila melanogaster, GI62472551, Length=137, Percent_Identity=39.4160583941606, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17136558, Length=137, Percent_Identity=39.4160583941606, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI19550181, Length=137, Percent_Identity=39.4160583941606, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI19550184, Length=137, Percent_Identity=39.4160583941606, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17136556, Length=137, Percent_Identity=39.4160583941606, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28571451, Length=138, Percent_Identity=36.9565217391304, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24639197, Length=138, Percent_Identity=36.9565217391304, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17737643, Length=114, Percent_Identity=36.8421052631579, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24647050, Length=132, Percent_Identity=35.6060606060606, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 17392; Mature: 17261

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50280 SET ; PS50868 POST_SET

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTVLIKKPAIDPRYAFFELAIRESKIHRRGVYALERIPARRKVIEYTGQKISRRETKRR
CCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHCC
GDGDITYLFTLDDYWTLDGAFGGSGAEIINHSCEPNLYAWNFKKHILYMSKRVIQRGEEL
CCCCEEEEEEECCEEEECCCCCCCCHHHHCCCCCCCEEEECHHHHHHHHHHHHHHCCCEE
TVDYRFSKDVERVPCLCGAKTCRGTINLLK
EEEEECCCCHHHCCHHCCCHHCCCEEEECC
>Mature Secondary Structure 
GTVLIKKPAIDPRYAFFELAIRESKIHRRGVYALERIPARRKVIEYTGQKISRRETKRR
CCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHCC
GDGDITYLFTLDDYWTLDGAFGGSGAEIINHSCEPNLYAWNFKKHILYMSKRVIQRGEEL
CCCCEEEEEEECCEEEECCCCCCCCHHHHCCCCCCCEEEECHHHHHHHHHHHHHHCCCEE
TVDYRFSKDVERVPCLCGAKTCRGTINLLK
EEEEECCCCHHHCCHHCCCHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA