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The map label for this gene is 116626227

Identifier: 116626227

GI number: 116626227

Start: 9026728

End: 9028848

Strand: Direct

Name: 116626227

Synonym: Acid_7187

Alternate gene names: NA

Gene position: 9026728-9028848 (Clockwise)

Preceding gene: 116626226

Following gene: 116626232

Centisome position: 90.58

GC content: 61.1

Gene sequence:

>2121_bases
GTGGCCAAGAAACACTCGCCGCAAAAACGGGCGGGCGCCGCGCCGGGAGTATTAGCTCCCGAAGCGCCGCTTCTGCGTGG
ACAGGCGGAGAGATTCGTTCCCGCGGCGATCGTCGTCCTCGGGGTGCTTTCCTATCTCAATAGCCTTCACACCCCGTTTA
TCTTTGACGATCGTTACCATATCGTCGAGAACCTGCGGATCCGGCACCTTTGGCCGCCGTGGGAGATCCTCACTCACAGT
TCCCGGCCTGTGATTCACCTCTCATTGGCGTTGAACTATGCGCTAGGCGGACTGGATCCCTGGGGATATCACGCGTTCAA
TATCTGCATCCACGTTCTTGCCGCCCTCGTGCTCTACGGAATCGTGCGCGCCACTTTTCTCTCCGATTCCTTGCGTCACC
GTTGGGCTCGCGTGGCAACGCCCCTCGCCGGCATGATCGCCGCCCTCTGGCTGGTGCATCCGATCCAGACCGAGAGCGTG
ACTTACACCATCCAGCGAGGCGAATCGCTGATGGGGCTTTTCTATCTCCTGACGCTCTATTGCGTGATTCGCCTGCACAA
TTCTTCACGGGGCAAGCTCTGGGGTGCAGCTGCGATCGCATGCTGCCTGTTCGGAATGAGTTGCAAGGGCGTAATGGCGA
CCGCCCCCATTGTGGTGCTGCTGTACGATCGCACATTTCTGTCGAGCTCCTGGGCGGAACTCGCCCAACGCCGAAAGGGC
CTCTATCTGGGCCTGGCTGCGACGTGGCTGGTTTATCCGTTGCTGCTGTCGCAAGCGCCCGAGGAGTGGAAGGATAGCGC
CGGGTTCAACTACGCCGGACTGTCTCCTTTCCAGTACGCGATCACGCAGCCCTCCGTGATCCTCCACTACCTTCGACTGG
CCTTTTGGCCAAGCGAGCTGTGCCTCGATTACGGTTGGCCTCCGGTGAAGGGAATCGGCGACGCCCTGGCGCCGGGAATC
GTGATCTGCGCATTGATTCTTGCATTCGTGTGGGCATGGCGCCGAAACGCCCCGCTGGGATTTTTCGGAATATGGTTCTT
TCTTATCCTGATCCCCACCTCGAGTTTCATACCGATCGCCGACCTGGCGGTTGAACACCGGATGTATCTGTCATTAGCCG
CGGTGATCGCTCTTGCGGTGACCGGCCTGGCGGCTCTTTCCCAGCGCCGGGCCGCCAAGGAGCCAATCCGAATTCCGGCG
GCCGGCTGGGTAGCATGCGCCCTCGTCATCGCAGTGTTCACCGCTCTCACCATCCGCCGCAACTCCGACTATTCGTCGAT
GCTTACGATGTGGGAATCCACGGTTCGCACCAGCCCAGGCAATCCGCGCGCGCACTACGATTTCGGAGTCAGCCTGGAAG
GCGCCGGCCAGACTCAGCCGGCGATCGCGCAGTATCAAACGGCGATTCAGCTGAATCCTGGTTACTCCGAAGCGCTCAAT
AATCTCGGCCATGCACTCTTGAAAGCCGGAAAGCCATCGGACAGCGTGGTGTATCTCCAGCGGGCGATTGCGATCAAGCC
GTCACTGCCTGAGACGCACACCAGTCTGGCGACCGCCTTGGCGCAGATCGGAAAATTCCAGGAGGCCGAGCGGGAATTCG
CGCAGGCGCTTCGCCTCAACCCGGATTACGAGGAGGCCCACAACAATCTGGGAATACTGCTATCCATGGAGCACAGGCCC
ACCGAGGCGATCGAGCACTGGACGCAAGCTCTGCGATTAAATCCGGCAATGCCCGATACCCACACCAATATCGCGACTGC
GCTCACGGAGACCGGCAGCATCCGCGAGGCGCTCGCGCACTACGATCAAGCCCTCCGCATCCAGCCCGATTATCTTCGGG
CGCAAATCGGCATGGCGAAATTATTGGCAACCGCCCAGGTCGCACAAGGCGGCGATCCGGTCCGGGCGGTGGCGATCGCG
GAGCGCGCCTGCCAGCTAACCGGCAACCGCGATCCGGTTTGCCTGGATACCCTCGCGATCTCGTATGCTGCGGCGAATCG
ATTCGACGATGCGCTCAAAACCGGACAGGCCGCCCTTCAGCTTGCCGGCTCCCAAGGCCTTGCGGACCTGAGCCGCGAGA
TCGAGGCTCACCTGCAGTTCTATCGCGCGCACCGCCGTTAG

Upstream 100 bases:

>100_bases
CATCCGCAGTGCAGATGGCTCTGTTGAGCTGACTCGCGGCGAAATTTTCGCGGAATAGTCACGTTCCCAGAGCCAAGAGC
CAGAGCTAATATAATAGGCC

Downstream 100 bases:

>100_bases
TTTCTACGATGCCGGCTGGCAGGCCTGGCGGAGCGCTTCGCCCATAATTTCCTGCTTCTCCGGAGTCAGCTTGACGCCAT
CAGCCGTGACATAGAAGACG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 706; Mature: 705

Protein sequence:

>706_residues
MAKKHSPQKRAGAAPGVLAPEAPLLRGQAERFVPAAIVVLGVLSYLNSLHTPFIFDDRYHIVENLRIRHLWPPWEILTHS
SRPVIHLSLALNYALGGLDPWGYHAFNICIHVLAALVLYGIVRATFLSDSLRHRWARVATPLAGMIAALWLVHPIQTESV
TYTIQRGESLMGLFYLLTLYCVIRLHNSSRGKLWGAAAIACCLFGMSCKGVMATAPIVVLLYDRTFLSSSWAELAQRRKG
LYLGLAATWLVYPLLLSQAPEEWKDSAGFNYAGLSPFQYAITQPSVILHYLRLAFWPSELCLDYGWPPVKGIGDALAPGI
VICALILAFVWAWRRNAPLGFFGIWFFLILIPTSSFIPIADLAVEHRMYLSLAAVIALAVTGLAALSQRRAAKEPIRIPA
AGWVACALVIAVFTALTIRRNSDYSSMLTMWESTVRTSPGNPRAHYDFGVSLEGAGQTQPAIAQYQTAIQLNPGYSEALN
NLGHALLKAGKPSDSVVYLQRAIAIKPSLPETHTSLATALAQIGKFQEAEREFAQALRLNPDYEEAHNNLGILLSMEHRP
TEAIEHWTQALRLNPAMPDTHTNIATALTETGSIREALAHYDQALRIQPDYLRAQIGMAKLLATAQVAQGGDPVRAVAIA
ERACQLTGNRDPVCLDTLAISYAAANRFDDALKTGQAALQLAGSQGLADLSREIEAHLQFYRAHRR

Sequences:

>Translated_706_residues
MAKKHSPQKRAGAAPGVLAPEAPLLRGQAERFVPAAIVVLGVLSYLNSLHTPFIFDDRYHIVENLRIRHLWPPWEILTHS
SRPVIHLSLALNYALGGLDPWGYHAFNICIHVLAALVLYGIVRATFLSDSLRHRWARVATPLAGMIAALWLVHPIQTESV
TYTIQRGESLMGLFYLLTLYCVIRLHNSSRGKLWGAAAIACCLFGMSCKGVMATAPIVVLLYDRTFLSSSWAELAQRRKG
LYLGLAATWLVYPLLLSQAPEEWKDSAGFNYAGLSPFQYAITQPSVILHYLRLAFWPSELCLDYGWPPVKGIGDALAPGI
VICALILAFVWAWRRNAPLGFFGIWFFLILIPTSSFIPIADLAVEHRMYLSLAAVIALAVTGLAALSQRRAAKEPIRIPA
AGWVACALVIAVFTALTIRRNSDYSSMLTMWESTVRTSPGNPRAHYDFGVSLEGAGQTQPAIAQYQTAIQLNPGYSEALN
NLGHALLKAGKPSDSVVYLQRAIAIKPSLPETHTSLATALAQIGKFQEAEREFAQALRLNPDYEEAHNNLGILLSMEHRP
TEAIEHWTQALRLNPAMPDTHTNIATALTETGSIREALAHYDQALRIQPDYLRAQIGMAKLLATAQVAQGGDPVRAVAIA
ERACQLTGNRDPVCLDTLAISYAAANRFDDALKTGQAALQLAGSQGLADLSREIEAHLQFYRAHRR
>Mature_705_residues
AKKHSPQKRAGAAPGVLAPEAPLLRGQAERFVPAAIVVLGVLSYLNSLHTPFIFDDRYHIVENLRIRHLWPPWEILTHSS
RPVIHLSLALNYALGGLDPWGYHAFNICIHVLAALVLYGIVRATFLSDSLRHRWARVATPLAGMIAALWLVHPIQTESVT
YTIQRGESLMGLFYLLTLYCVIRLHNSSRGKLWGAAAIACCLFGMSCKGVMATAPIVVLLYDRTFLSSSWAELAQRRKGL
YLGLAATWLVYPLLLSQAPEEWKDSAGFNYAGLSPFQYAITQPSVILHYLRLAFWPSELCLDYGWPPVKGIGDALAPGIV
ICALILAFVWAWRRNAPLGFFGIWFFLILIPTSSFIPIADLAVEHRMYLSLAAVIALAVTGLAALSQRRAAKEPIRIPAA
GWVACALVIAVFTALTIRRNSDYSSMLTMWESTVRTSPGNPRAHYDFGVSLEGAGQTQPAIAQYQTAIQLNPGYSEALNN
LGHALLKAGKPSDSVVYLQRAIAIKPSLPETHTSLATALAQIGKFQEAEREFAQALRLNPDYEEAHNNLGILLSMEHRPT
EAIEHWTQALRLNPAMPDTHTNIATALTETGSIREALAHYDQALRIQPDYLRAQIGMAKLLATAQVAQGGDPVRAVAIAE
RACQLTGNRDPVCLDTLAISYAAANRFDDALKTGQAALQLAGSQGLADLSREIEAHLQFYRAHRR

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI118766330, Length=718, Percent_Identity=24.0947075208914, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI118766328, Length=718, Percent_Identity=24.0947075208914, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI224809432, Length=687, Percent_Identity=23.1441048034935, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI83415184, Length=403, Percent_Identity=26.5508684863524, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI301336134, Length=403, Percent_Identity=26.5508684863524, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI32307148, Length=225, Percent_Identity=29.3333333333333, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI32307150, Length=225, Percent_Identity=29.3333333333333, Blast_Score=116, Evalue=7e-26,
Organism=Homo sapiens, GI22749211, Length=176, Percent_Identity=36.3636363636364, Blast_Score=69, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147174, Length=641, Percent_Identity=26.2090483619345, Blast_Score=156, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI115532692, Length=192, Percent_Identity=28.125, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI115532690, Length=192, Percent_Identity=28.125, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17560436, Length=759, Percent_Identity=19.3675889328063, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24647123, Length=686, Percent_Identity=23.6151603498542, Blast_Score=159, Evalue=6e-39,
Organism=Drosophila melanogaster, GI17647755, Length=195, Percent_Identity=28.7179487179487, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24585827, Length=195, Percent_Identity=28.7179487179487, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24585829, Length=195, Percent_Identity=28.7179487179487, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24656717, Length=315, Percent_Identity=24.7619047619048, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI18110006, Length=315, Percent_Identity=24.7619047619048, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24581187, Length=205, Percent_Identity=30.7317073170732, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281364285, Length=205, Percent_Identity=30.7317073170732, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI161076610, Length=204, Percent_Identity=30.3921568627451, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19920486, Length=204, Percent_Identity=30.3921568627451, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 77561; Mature: 77430

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKHSPQKRAGAAPGVLAPEAPLLRGQAERFVPAAIVVLGVLSYLNSLHTPFIFDDRYH
CCCCCCCHHHCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHH
IVENLRIRHLWPPWEILTHSSRPVIHLSLALNYALGGLDPWGYHAFNICIHVLAALVLYG
HHHCCEEEECCCCHHHHCCCCCCEEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
IVRATFLSDSLRHRWARVATPLAGMIAALWLVHPIQTESVTYTIQRGESLMGLFYLLTLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHH
CVIRLHNSSRGKLWGAAAIACCLFGMSCKGVMATAPIVVLLYDRTFLSSSWAELAQRRKG
HHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCEEEEEECHHHHHHHHHHHHHHHCC
LYLGLAATWLVYPLLLSQAPEEWKDSAGFNYAGLSPFQYAITQPSVILHYLRLAFWPSEL
EEEHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCHHH
CLDYGWPPVKGIGDALAPGIVICALILAFVWAWRRNAPLGFFGIWFFLILIPTSSFIPIA
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHH
DLAVEHRMYLSLAAVIALAVTGLAALSQRRAAKEPIRIPAAGWVACALVIAVFTALTIRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
NSDYSSMLTMWESTVRTSPGNPRAHYDFGVSLEGAGQTQPAIAQYQTAIQLNPGYSEALN
CCCHHHHHHHHHHHHHCCCCCCCCEEEECEEECCCCCCCHHHHHHHHHEEECCCHHHHHH
NLGHALLKAGKPSDSVVYLQRAIAIKPSLPETHTSLATALAQIGKFQEAEREFAQALRLN
HHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDYEEAHNNLGILLSMEHRPTEAIEHWTQALRLNPAMPDTHTNIATALTETGSIREALAH
CCHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHH
YDQALRIQPDYLRAQIGMAKLLATAQVAQGGDPVRAVAIAERACQLTGNRDPVCLDTLAI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHH
SYAAANRFDDALKTGQAALQLAGSQGLADLSREIEAHLQFYRAHRR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKKHSPQKRAGAAPGVLAPEAPLLRGQAERFVPAAIVVLGVLSYLNSLHTPFIFDDRYH
CCCCCCHHHCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHH
IVENLRIRHLWPPWEILTHSSRPVIHLSLALNYALGGLDPWGYHAFNICIHVLAALVLYG
HHHCCEEEECCCCHHHHCCCCCCEEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
IVRATFLSDSLRHRWARVATPLAGMIAALWLVHPIQTESVTYTIQRGESLMGLFYLLTLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHH
CVIRLHNSSRGKLWGAAAIACCLFGMSCKGVMATAPIVVLLYDRTFLSSSWAELAQRRKG
HHHHHCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCEEEEEECHHHHHHHHHHHHHHHCC
LYLGLAATWLVYPLLLSQAPEEWKDSAGFNYAGLSPFQYAITQPSVILHYLRLAFWPSEL
EEEHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCHHH
CLDYGWPPVKGIGDALAPGIVICALILAFVWAWRRNAPLGFFGIWFFLILIPTSSFIPIA
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHH
DLAVEHRMYLSLAAVIALAVTGLAALSQRRAAKEPIRIPAAGWVACALVIAVFTALTIRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
NSDYSSMLTMWESTVRTSPGNPRAHYDFGVSLEGAGQTQPAIAQYQTAIQLNPGYSEALN
CCCHHHHHHHHHHHHHCCCCCCCCEEEECEEECCCCCCCHHHHHHHHHEEECCCHHHHHH
NLGHALLKAGKPSDSVVYLQRAIAIKPSLPETHTSLATALAQIGKFQEAEREFAQALRLN
HHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDYEEAHNNLGILLSMEHRPTEAIEHWTQALRLNPAMPDTHTNIATALTETGSIREALAH
CCHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHH
YDQALRIQPDYLRAQIGMAKLLATAQVAQGGDPVRAVAIAERACQLTGNRDPVCLDTLAI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHH
SYAAANRFDDALKTGQAALQLAGSQGLADLSREIEAHLQFYRAHRR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]