Click here to switch to the map view.

The map label for this gene is argK [C]

Identifier: 116626101

GI number: 116626101

Start: 8876331

End: 8877476

Strand: Reverse

Name: argK [C]

Synonym: Acid_7059

Alternate gene names: 116626101

Gene position: 8877476-8876331 (Counterclockwise)

Preceding gene: 116626102

Following gene: 116626100

Centisome position: 89.08

GC content: 66.32

Gene sequence:

>1146_bases
ATGAACGAACAGGCGCGAAAAATCCGCGAAGGGGACGCGCGCGCGCTGGCGCGCCTGGCCACCGGCATCGAGAACCGCGA
TGCGCAGGCACTCGAAACCCTGCGCGAATTGGAGCCTTTCGCCGGACACGCGCGCATCGTGGGCATCACCGGGCCGCCGG
GCGCTGGCAAGAGCACGCTGGTGGACGCGCTGGCAGTGGAACTCCGCAAGCGCGGCAAGACGCTCGCGATCCTCGCCGTC
GATCCGAGCAGCCGCAACACCGGCGGCGCCATTCTGGGCGACCGCATCCGCATGCAGCAGCATCACGCCGACCCCGGCAT
CTTTATACGCTCGATGGCGACGCGCGGCACGTTGGGCGGCATGGCGCGTGCCACGGCAGATCTCGCGCGCCTGATGGACG
CCGCGGGCAAAGACTACGTCGTCATCGAAACCGTTGGCGTGGGGCAGGACGAGATCGAAATCACGTCGGTGGCGCAGGTG
ACGGTGGTCGTGCTGGTCCCCGGGATGGGCGACGATGTGCAGGCCCTCAAGGCAGGCATCATGGAGATCGCCGACATCTT
CGTCATCAACAAGAGCGATCATCCCGGCGCGGAGCGCGTGGAAATGGAACTGCACGCGGAGGGCTTCACTTGTCCCGTCA
TCCGCACCGTCGCGAGCGAGGGCATGGGCATCTCGAGCCTTGTGGAAGCTATCAATGCCCCGCCGCATCGCGCCACAGAG
CCGCGACCGTTAGGGAGCGATCGCGCCGGCGCCTCCATCGACCACCTCGGGATCGCCGTGCAGTCGCTGGAAGACGCCAT
TCGCTTTTACGAATCGCTCGGCCTCGCGGTCGTGCGCCGCGAAACCGTCGCTACGGAAAAGGTGGACGCCGCCATGCTCC
CGGTCGGCAATTCGCGGATCGAACTCTTGCAGGCATCCGCGCCCGATTCACCGATCGCGAAGTTTCTCCAAAAGCGCGGT
CCCGGGCTGCATCACGTCGCCTTACGTGTGCCGGATCTCAACGCGGCCGTCGCCGGGCTTAAGGCCAGCGGAGCGCGCCT
GTTGAACGAGCCGCGCGCCGGCGCCGGCGGCCACATCTACGTCTTTGTCCATCCCGCCTCCACCGGAGGCGTGTTGTTGG
AACTCATTCAGGAGAGCACCAATTGA

Upstream 100 bases:

>100_bases
CGGTGGAGAAGTTCTATCGCGACGTCAAGCTGTGCACCATCGGAGAGGGCACCAGCGAGATCCAGCGCCTGGTGATCGCA
CGGCAATTACTCAAGAGCTG

Downstream 100 bases:

>100_bases
AAGCGGAAATCGGAATCATCGGGGGCAGCGGACTGTACCACATGCCCGGATTTGAAGCGCAGGAGGAGGCCAACATCACC
ACGCCATTCGGCAGCCCCTC

Product: LAO/AO transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MNEQARKIREGDARALARLATGIENRDAQALETLRELEPFAGHARIVGITGPPGAGKSTLVDALAVELRKRGKTLAILAV
DPSSRNTGGAILGDRIRMQQHHADPGIFIRSMATRGTLGGMARATADLARLMDAAGKDYVVIETVGVGQDEIEITSVAQV
TVVVLVPGMGDDVQALKAGIMEIADIFVINKSDHPGAERVEMELHAEGFTCPVIRTVASEGMGISSLVEAINAPPHRATE
PRPLGSDRAGASIDHLGIAVQSLEDAIRFYESLGLAVVRRETVATEKVDAAMLPVGNSRIELLQASAPDSPIAKFLQKRG
PGLHHVALRVPDLNAAVAGLKASGARLLNEPRAGAGGHIYVFVHPASTGGVLLELIQESTN

Sequences:

>Translated_381_residues
MNEQARKIREGDARALARLATGIENRDAQALETLRELEPFAGHARIVGITGPPGAGKSTLVDALAVELRKRGKTLAILAV
DPSSRNTGGAILGDRIRMQQHHADPGIFIRSMATRGTLGGMARATADLARLMDAAGKDYVVIETVGVGQDEIEITSVAQV
TVVVLVPGMGDDVQALKAGIMEIADIFVINKSDHPGAERVEMELHAEGFTCPVIRTVASEGMGISSLVEAINAPPHRATE
PRPLGSDRAGASIDHLGIAVQSLEDAIRFYESLGLAVVRRETVATEKVDAAMLPVGNSRIELLQASAPDSPIAKFLQKRG
PGLHHVALRVPDLNAAVAGLKASGARLLNEPRAGAGGHIYVFVHPASTGGVLLELIQESTN
>Mature_381_residues
MNEQARKIREGDARALARLATGIENRDAQALETLRELEPFAGHARIVGITGPPGAGKSTLVDALAVELRKRGKTLAILAV
DPSSRNTGGAILGDRIRMQQHHADPGIFIRSMATRGTLGGMARATADLARLMDAAGKDYVVIETVGVGQDEIEITSVAQV
TVVVLVPGMGDDVQALKAGIMEIADIFVINKSDHPGAERVEMELHAEGFTCPVIRTVASEGMGISSLVEAINAPPHRATE
PRPLGSDRAGASIDHLGIAVQSLEDAIRFYESLGLAVVRRETVATEKVDAAMLPVGNSRIELLQASAPDSPIAKFLQKRG
PGLHHVALRVPDLNAAVAGLKASGARLLNEPRAGAGGHIYVFVHPASTGGVLLELIQESTN

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=198, Percent_Identity=40.4040404040404, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI188035928, Length=172, Percent_Identity=36.046511627907, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1789285, Length=195, Percent_Identity=43.0769230769231, Blast_Score=152, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71994271, Length=148, Percent_Identity=45.2702702702703, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71994275, Length=148, Percent_Identity=45.2702702702703, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17506387, Length=128, Percent_Identity=38.28125, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 40098; Mature: 40098

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEQARKIREGDARALARLATGIENRDAQALETLRELEPFAGHARIVGITGPPGAGKSTL
CCHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHH
VDALAVELRKRGKTLAILAVDPSSRNTGGAILGDRIRMQQHHADPGIFIRSMATRGTLGG
HHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEHHHHCCCCCH
MARATADLARLMDAAGKDYVVIETVGVGQDEIEITSVAQVTVVVLVPGMGDDVQALKAGI
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEEEEEEEEECCCCCHHHHHHHHH
MEIADIFVINKSDHPGAERVEMELHAEGFTCPVIRTVASEGMGISSLVEAINAPPHRATE
HHHHHEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC
PRPLGSDRAGASIDHLGIAVQSLEDAIRFYESLGLAVVRRETVATEKVDAAMLPVGNSRI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCEEEECCCCCCE
ELLQASAPDSPIAKFLQKRGPGLHHVALRVPDLNAAVAGLKASGARLLNEPRAGAGGHIY
EEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHCCCCCCHHHHCCCCCCCCCEEE
VFVHPASTGGVLLELIQESTN
EEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNEQARKIREGDARALARLATGIENRDAQALETLRELEPFAGHARIVGITGPPGAGKSTL
CCHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHH
VDALAVELRKRGKTLAILAVDPSSRNTGGAILGDRIRMQQHHADPGIFIRSMATRGTLGG
HHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEHHHHCCCCCH
MARATADLARLMDAAGKDYVVIETVGVGQDEIEITSVAQVTVVVLVPGMGDDVQALKAGI
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEEEEEEEEECCCCCHHHHHHHHH
MEIADIFVINKSDHPGAERVEMELHAEGFTCPVIRTVASEGMGISSLVEAINAPPHRATE
HHHHHEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCC
PRPLGSDRAGASIDHLGIAVQSLEDAIRFYESLGLAVVRRETVATEKVDAAMLPVGNSRI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCEEEECCCCCCE
ELLQASAPDSPIAKFLQKRGPGLHHVALRVPDLNAAVAGLKASGARLLNEPRAGAGGHIY
EEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHCCCCCCHHHHCCCCCCCCCEEE
VFVHPASTGGVLLELIQESTN
EEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]