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The map label for this gene is dapA [H]

Identifier: 116626022

GI number: 116626022

Start: 8768075

End: 8768965

Strand: Reverse

Name: dapA [H]

Synonym: Acid_6980

Alternate gene names: 116626022

Gene position: 8768965-8768075 (Counterclockwise)

Preceding gene: 116626023

Following gene: 116626021

Centisome position: 87.99

GC content: 62.4

Gene sequence:

>891_bases
ATGTTTACCGGATGCGGGACAGCGCTAGTCACACCATTTCGTAGAGATCTTTCTTTAGATGAAGCGACGCTGCGCGGGTT
GGTGCGCAGGCAGATCGAGGCGGGGATCAATTTTCTGGTGCCGTGCGGCACTACCGGGGAGAGCCCGACCTTGAGCCGGG
CCGAGCATTTGCGGGTGGTTGAGATCACGCTCGAAGAGGCCAAGGGCAAAGTCCCGGTGCTGGCGGGCGCGGGCGGGTAC
AACACGCACGAAGTGATCGAACTGGCGCGGGAACTGGAAAGCATGGGCGCGGACGGGATCCTTTCGGTCACGCCTTACTA
CAACAAGCCGACGCAGGAAGGGCTATACCAGCACTACTGCGCGATCGCCGATGGCACGCGACTGCCGATCGTGGTCTACA
GCGTGCAGGGGCGCACGGGGGTCAACGTTGAGCCGGGGACGCTGGCGCGGCTCGCGAAGATCGGCAACATCGTTGCGGTG
AAAGAGGCGAGCGGCAACATCGGGCAGATGGCCACAATCCTCAATGAAGTGCCGGGCGATTTCATCGTGCTCTCGGGCGA
CGATGCGATCACGATTCCGCTGGCGGCACTGGGCGGGCGCGGCATCATCTCGGTGGCGTCCAACGAGATTCCCGCGGAGA
TGACGCAGATCGCGCAGGCATGCCTGCGCGGCGATTTCGCAGCGGCGCGCGCGATCCAAGCGAAATTTCTGCCGCTGATG
AACGTGAATTTTGTCGAAAGCAACCCGATTCCGGTGAAGGCCGCGATGGCCTTGATGGGTCTGCTCGAACCGGTTTGGCG
GCTGCCGATGGTGCCGCCGACTCCGGCGAGCCTGGCGAAGATTGAGAACGTGCTCGAAAGCGTCGGACTCCTGGTACATC
ATGCAAGCTGA

Upstream 100 bases:

>100_bases
CTTTTACGAGTTCAGTGAGATTGCGTTTTAGGCCAGGAAGAGAATGGGCCGCGGATGAACGCGGATGAACGCAGATGAAA
ACGAGGGCGGGAGGTGGTAC

Downstream 100 bases:

>100_bases
GATCGAGCGGCTTTTCGAGAATCCTCCGGCGGAGTACACGGCGGAGCATAGAAATCTTTTTGGTGCCTTTCTCACCGCGC
TGACGGAGGGAAGGGTGCGC

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MFTGCGTALVTPFRRDLSLDEATLRGLVRRQIEAGINFLVPCGTTGESPTLSRAEHLRVVEITLEEAKGKVPVLAGAGGY
NTHEVIELARELESMGADGILSVTPYYNKPTQEGLYQHYCAIADGTRLPIVVYSVQGRTGVNVEPGTLARLAKIGNIVAV
KEASGNIGQMATILNEVPGDFIVLSGDDAITIPLAALGGRGIISVASNEIPAEMTQIAQACLRGDFAAARAIQAKFLPLM
NVNFVESNPIPVKAAMALMGLLEPVWRLPMVPPTPASLAKIENVLESVGLLVHHAS

Sequences:

>Translated_296_residues
MFTGCGTALVTPFRRDLSLDEATLRGLVRRQIEAGINFLVPCGTTGESPTLSRAEHLRVVEITLEEAKGKVPVLAGAGGY
NTHEVIELARELESMGADGILSVTPYYNKPTQEGLYQHYCAIADGTRLPIVVYSVQGRTGVNVEPGTLARLAKIGNIVAV
KEASGNIGQMATILNEVPGDFIVLSGDDAITIPLAALGGRGIISVASNEIPAEMTQIAQACLRGDFAAARAIQAKFLPLM
NVNFVESNPIPVKAAMALMGLLEPVWRLPMVPPTPASLAKIENVLESVGLLVHHAS
>Mature_296_residues
MFTGCGTALVTPFRRDLSLDEATLRGLVRRQIEAGINFLVPCGTTGESPTLSRAEHLRVVEITLEEAKGKVPVLAGAGGY
NTHEVIELARELESMGADGILSVTPYYNKPTQEGLYQHYCAIADGTRLPIVVYSVQGRTGVNVEPGTLARLAKIGNIVAV
KEASGNIGQMATILNEVPGDFIVLSGDDAITIPLAALGGRGIISVASNEIPAEMTQIAQACLRGDFAAARAIQAKFLPLM
NVNFVESNPIPVKAAMALMGLLEPVWRLPMVPPTPASLAKIENVLESVGLLVHHAS

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=287, Percent_Identity=26.4808362369338, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI13540533, Length=247, Percent_Identity=25.9109311740891, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788823, Length=292, Percent_Identity=44.5205479452055, Blast_Score=247, Evalue=6e-67,
Organism=Escherichia coli, GI87082415, Length=296, Percent_Identity=30.4054054054054, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789620, Length=287, Percent_Identity=30.6620209059233, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786463, Length=280, Percent_Identity=29.6428571428571, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31329; Mature: 31329

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGCGTALVTPFRRDLSLDEATLRGLVRRQIEAGINFLVPCGTTGESPTLSRAEHLRVV
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHCEEEE
EITLEEAKGKVPVLAGAGGYNTHEVIELARELESMGADGILSVTPYYNKPTQEGLYQHYC
EEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHH
AIADGTRLPIVVYSVQGRTGVNVEPGTLARLAKIGNIVAVKEASGNIGQMATILNEVPGD
HHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCC
FIVLSGDDAITIPLAALGGRGIISVASNEIPAEMTQIAQACLRGDFAAARAIQAKFLPLM
EEEECCCCEEEEEHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
NVNFVESNPIPVKAAMALMGLLEPVWRLPMVPPTPASLAKIENVLESVGLLVHHAS
CCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MFTGCGTALVTPFRRDLSLDEATLRGLVRRQIEAGINFLVPCGTTGESPTLSRAEHLRVV
CCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHCEEEE
EITLEEAKGKVPVLAGAGGYNTHEVIELARELESMGADGILSVTPYYNKPTQEGLYQHYC
EEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHH
AIADGTRLPIVVYSVQGRTGVNVEPGTLARLAKIGNIVAVKEASGNIGQMATILNEVPGD
HHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCC
FIVLSGDDAITIPLAALGGRGIISVASNEIPAEMTQIAQACLRGDFAAARAIQAKFLPLM
EEEECCCCEEEEEHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
NVNFVESNPIPVKAAMALMGLLEPVWRLPMVPPTPASLAKIENVLESVGLLVHHAS
CCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA