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The map label for this gene is ygfH [H]

Identifier: 116625995

GI number: 116625995

Start: 8741189

End: 8742703

Strand: Reverse

Name: ygfH [H]

Synonym: Acid_6953

Alternate gene names: 116625995

Gene position: 8742703-8741189 (Counterclockwise)

Preceding gene: 116625996

Following gene: 116625994

Centisome position: 87.73

GC content: 61.45

Gene sequence:

>1515_bases
ATGAAACTTCCGTTTCCCGTACTTACCGCGGCCGAGGCCGCCTCATTAATTGATAACGGACAGAACGTCGGCTTCAGTGG
CTTCACCCCGGCCGGCGCGCCGAAAGCCGTGCCGATGGCGATCGCCGATCGCGCAATTGCCGCTCACGATGCCGGACAGG
AGTTCCAGATCGGAGTTCTGACCGGCGCCTCGACCGGCCCCTCGCTCGACGGCGCGCTCTCCAAAGCGAAGGCGATGAAG
TTCCGCACGCCGTACCAGACCGATTCCAATCTGCGCGACCGCATCAACGCCGGCAAGACGCGCTTCTTCGACCTTCACCT
CTCTCTGATGCCGCAGGTGACTCGCTATGGCTTCCTTGGCAAGGTGGACGTGGCCGTGGTGGAAGCGGCCGACTTGACCG
CGGGCGGCGGGATTGTGCTGACCTCCGGAGTCGGCGCCGCGCCCACATTCTGCAACCTGGCGGACCGCGTGATCGTCGAA
CTCAACCGCCACCATCCGGCCGCACTCCTGGGACTTCACGACATCTATGAGCCCGCGGATCCGCCCTATCGCAAGCAGAT
TCCCATCTACAAGCCTTCGGACCGCATCGGCTCGCCGATCATCACGATCGATCCGGCGAAAATCGTCGGCGTGGTGGAAA
CCGATCTTGAGGACGAAGCCCGCGGTTTCAGTGAGATCAGCCCACTTACCGAATCGATCGGCCACAACGTCGCCGAGTTT
CTGGCGGCTCAATTGGCCGCGGGTATGATTCCTAAGCCGTTTCTGCCGATTCAGTCGGGCGTGGGCGATATCGCCAACTC
CGTGCTGGGCGCGCTCGGCAGTCATCCCGGGATTCCGCCCTTCGAGATGTATACCGAAGTGCTGCAGGATTCGGTGGTAG
ACCTGATCGAGCGGGAGCGCGTGACCTTCGCGAGCAGTTGTTCGTTTACGGTTACGCCTCCGGCCTTGAGGCGAGTCTAT
GAGAACTTGAAGTTCTTTCGGTCCCGCGTCCTGTTGCGCCCGCAGGAGATCAGCAACAGCCCGGAAATCATCCGGCGGCT
GGGCATCATCTCGGTGAACACCGCCATCGAAGTCGATATCTTCGGCAATGTGAACAGCACGCACGTGATGGGCCGGAAAT
TGATGAACGGCATCGGCGGTTCGGGCGATTTCACGCGCAACGCGTATCTTTCGGTATTTACCTGCCCGTCGGTCGCCAAG
GGTGGAAAGATCAGCACGATCGTTCCGCTGGTATCGCACGTCGATCATAGCGAGCACTCGGTGCAGATCATCGCGACCGA
ATTCGGCGTGGCCGATCTCCGGGGCAAGTCGCCGTTCGAACGCGCGAATGAGATTATCGACAACTGCGCGCACCCCGACT
ACCGGGAACTGCTGCGCAGCTACCTGAACATCGTCGAAGGCGGCCATACCCCGCACACTCTGTCGGCGGCCTTCCGAATG
CACGAGCACTTCCAAAAGACCGGCGACATGCATGGCTGCACTTGGGACGCGCCCGTGCTGACCGGGATCTCGTAG

Upstream 100 bases:

>100_bases
GGCTGCCGCTACTCCGGGAAGAAGTGCGGCGCGGACGCATCACTCCGTTCGCGGCCAGCCGCGAGCTGCTGGCGCTCTTC
CAATTACAAAGCGAGATTTT

Downstream 100 bases:

>100_bases
GCCCCCGCCCATCGTTAGAAATATCCGCGGAAGCCGGTTGCCTCGAGGGACCGGTTTCCGCTCGAATTTCTTGAGCCTGT
TTTCCTCCAAGCGCATCGAT

Product: Acetyl-CoA hydrolase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MKLPFPVLTAAEAASLIDNGQNVGFSGFTPAGAPKAVPMAIADRAIAAHDAGQEFQIGVLTGASTGPSLDGALSKAKAMK
FRTPYQTDSNLRDRINAGKTRFFDLHLSLMPQVTRYGFLGKVDVAVVEAADLTAGGGIVLTSGVGAAPTFCNLADRVIVE
LNRHHPAALLGLHDIYEPADPPYRKQIPIYKPSDRIGSPIITIDPAKIVGVVETDLEDEARGFSEISPLTESIGHNVAEF
LAAQLAAGMIPKPFLPIQSGVGDIANSVLGALGSHPGIPPFEMYTEVLQDSVVDLIERERVTFASSCSFTVTPPALRRVY
ENLKFFRSRVLLRPQEISNSPEIIRRLGIISVNTAIEVDIFGNVNSTHVMGRKLMNGIGGSGDFTRNAYLSVFTCPSVAK
GGKISTIVPLVSHVDHSEHSVQIIATEFGVADLRGKSPFERANEIIDNCAHPDYRELLRSYLNIVEGGHTPHTLSAAFRM
HEHFQKTGDMHGCTWDAPVLTGIS

Sequences:

>Translated_504_residues
MKLPFPVLTAAEAASLIDNGQNVGFSGFTPAGAPKAVPMAIADRAIAAHDAGQEFQIGVLTGASTGPSLDGALSKAKAMK
FRTPYQTDSNLRDRINAGKTRFFDLHLSLMPQVTRYGFLGKVDVAVVEAADLTAGGGIVLTSGVGAAPTFCNLADRVIVE
LNRHHPAALLGLHDIYEPADPPYRKQIPIYKPSDRIGSPIITIDPAKIVGVVETDLEDEARGFSEISPLTESIGHNVAEF
LAAQLAAGMIPKPFLPIQSGVGDIANSVLGALGSHPGIPPFEMYTEVLQDSVVDLIERERVTFASSCSFTVTPPALRRVY
ENLKFFRSRVLLRPQEISNSPEIIRRLGIISVNTAIEVDIFGNVNSTHVMGRKLMNGIGGSGDFTRNAYLSVFTCPSVAK
GGKISTIVPLVSHVDHSEHSVQIIATEFGVADLRGKSPFERANEIIDNCAHPDYRELLRSYLNIVEGGHTPHTLSAAFRM
HEHFQKTGDMHGCTWDAPVLTGIS
>Mature_504_residues
MKLPFPVLTAAEAASLIDNGQNVGFSGFTPAGAPKAVPMAIADRAIAAHDAGQEFQIGVLTGASTGPSLDGALSKAKAMK
FRTPYQTDSNLRDRINAGKTRFFDLHLSLMPQVTRYGFLGKVDVAVVEAADLTAGGGIVLTSGVGAAPTFCNLADRVIVE
LNRHHPAALLGLHDIYEPADPPYRKQIPIYKPSDRIGSPIITIDPAKIVGVVETDLEDEARGFSEISPLTESIGHNVAEF
LAAQLAAGMIPKPFLPIQSGVGDIANSVLGALGSHPGIPPFEMYTEVLQDSVVDLIERERVTFASSCSFTVTPPALRRVY
ENLKFFRSRVLLRPQEISNSPEIIRRLGIISVNTAIEVDIFGNVNSTHVMGRKLMNGIGGSGDFTRNAYLSVFTCPSVAK
GGKISTIVPLVSHVDHSEHSVQIIATEFGVADLRGKSPFERANEIIDNCAHPDYRELLRSYLNIVEGGHTPHTLSAAFRM
HEHFQKTGDMHGCTWDAPVLTGIS

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=492, Percent_Identity=53.2520325203252, Blast_Score=535, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI32563853, Length=471, Percent_Identity=25.4777070063694, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17538151, Length=280, Percent_Identity=29.2857142857143, Blast_Score=87, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319456, Length=509, Percent_Identity=39.6856581532416, Blast_Score=371, Evalue=1e-103,
Organism=Drosophila melanogaster, GI21358615, Length=257, Percent_Identity=28.0155642023346, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 54147; Mature: 54147

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPFPVLTAAEAASLIDNGQNVGFSGFTPAGAPKAVPMAIADRAIAAHDAGQEFQIGVL
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEE
TGASTGPSLDGALSKAKAMKFRTPYQTDSNLRDRINAGKTRFFDLHLSLMPQVTRYGFLG
ECCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEEEEHHHHHHHHHHCCCCC
KVDVAVVEAADLTAGGGIVLTSGVGAAPTFCNLADRVIVELNRHHPAALLGLHDIYEPAD
CEEEEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
PPYRKQIPIYKPSDRIGSPIITIDPAKIVGVVETDLEDEARGFSEISPLTESIGHNVAEF
CCCCCCCCCCCCCHHHCCCEEEECHHHEEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHH
LAAQLAAGMIPKPFLPIQSGVGDIANSVLGALGSHPGIPPFEMYTEVLQDSVVDLIERER
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
VTFASSCSFTVTPPALRRVYENLKFFRSRVLLRPQEISNSPEIIRRLGIISVNTAIEVDI
CEEECCCCEEECCHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHCEEEECCEEEEEE
FGNVNSTHVMGRKLMNGIGGSGDFTRNAYLSVFTCPSVAKGGKISTIVPLVSHVDHSEHS
ECCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCC
VQIIATEFGVADLRGKSPFERANEIIDNCAHPDYRELLRSYLNIVEGGHTPHTLSAAFRM
EEEEEEECCCHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
HEHFQKTGDMHGCTWDAPVLTGIS
HHHHHHCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MKLPFPVLTAAEAASLIDNGQNVGFSGFTPAGAPKAVPMAIADRAIAAHDAGQEFQIGVL
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEE
TGASTGPSLDGALSKAKAMKFRTPYQTDSNLRDRINAGKTRFFDLHLSLMPQVTRYGFLG
ECCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEEEEHHHHHHHHHHCCCCC
KVDVAVVEAADLTAGGGIVLTSGVGAAPTFCNLADRVIVELNRHHPAALLGLHDIYEPAD
CEEEEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC
PPYRKQIPIYKPSDRIGSPIITIDPAKIVGVVETDLEDEARGFSEISPLTESIGHNVAEF
CCCCCCCCCCCCCHHHCCCEEEECHHHEEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHH
LAAQLAAGMIPKPFLPIQSGVGDIANSVLGALGSHPGIPPFEMYTEVLQDSVVDLIERER
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
VTFASSCSFTVTPPALRRVYENLKFFRSRVLLRPQEISNSPEIIRRLGIISVNTAIEVDI
CEEECCCCEEECCHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHCEEEECCEEEEEE
FGNVNSTHVMGRKLMNGIGGSGDFTRNAYLSVFTCPSVAKGGKISTIVPLVSHVDHSEHS
ECCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCC
VQIIATEFGVADLRGKSPFERANEIIDNCAHPDYRELLRSYLNIVEGGHTPHTLSAAFRM
EEEEEEECCCHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHH
HEHFQKTGDMHGCTWDAPVLTGIS
HHHHHHCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]