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The map label for this gene is argK [H]

Identifier: 116625996

GI number: 116625996

Start: 8742700

End: 8743707

Strand: Reverse

Name: argK [H]

Synonym: Acid_6954

Alternate gene names: 116625996

Gene position: 8743707-8742700 (Counterclockwise)

Preceding gene: 116625997

Following gene: 116625995

Centisome position: 87.74

GC content: 63.79

Gene sequence:

>1008_bases
ATGCGCCGTCCGAAGCGTTTGCCGCTGGAGCGATATGTCGAAGGGGTGTTGGCCGGGGACCGCACGATCCTGGCCCGCGC
CATCACGGTCATCGAGAGTAATCTGCCGTCCGATGGTGAACTAGCTGCGCACCTGTTGGACGCACTGCTGCCGCACACCG
GCCAGGCGCTGCGTGTAGGTATCACGGGAGTGCCAGGCGTCGGCAAAAGCACGTTCGTAGACGCCTTGGGCATGCACCTC
ATCGCCGAACGCGGCGAGAACGTGGCGGTGCTCAGCGTCGATCCCTCGAGCCCGATCTCCGGCGGCAGCATCCTGGGCGA
TAAGACCCGTATGGAGCGGCTCGCCGTGAACGAGCGCGCCTTCATCCGGCCATCGCCTTCGCAGGGCCACCTCGGCGGCG
TGGCGCGCCGTACCCGCGAGACCATTCTGCTCTGCGAGGCCGCCGGATACCGGAACATCCTGGTGGAGACAGTCGGCGTG
GGACAAAGTGAAACCGCGGTCCGTTCGATGACGGATTTCTTTCTCCTGCTGATGCTGGCGGGCGCGGGCGATGAGTTGCA
AGGAGTGAAGCGAGGCATCATCGAAATGCTCGACGGCATGGCCATCAACAAAGCCGACGGCGATAACCGGGTCAAAGCCG
AGCGCGCGCGAGTTGAGTATGCCGGCGCGCTTCACCTCTTTCCGGCGTCGGCGGATGGCTGGACGCCGCGTGTGTTGACG
TGCTCGGCCATTGCCAAAGAGGGAATTTCCGAACTGTGGCAAATGGTGCTGGATCACCGCGCACTGCTCGAAGGCAACGG
TTGCCTCGCCCGGCTCCGCAACCTTCAGGCGCTCCACTGGATGAACGAGTTGACGATGCTGGGATTGGAAGATCTCTTCC
GCGCCAACCAGGCTGTGGCCCGACGGCTGCCGCTACTCCGGGAAGAAGTGCGGCGCGGACGCATCACTCCGTTCGCGGCC
AGCCGCGAGCTGCTGGCGCTCTTCCAATTACAAAGCGAGATTTTATGA

Upstream 100 bases:

>100_bases
CCGTGGTTCGCGAGTGCCTTTCAATAGATCGCTCCCTAACCGTCGCGGCTCGGATGGGACAGACTCAGCAAGTGGACAGG
CCAGGAGGCCTATCCCACTA

Downstream 100 bases:

>100_bases
AACTTCCGTTTCCCGTACTTACCGCGGCCGAGGCCGCCTCATTAATTGATAACGGACAGAACGTCGGCTTCAGTGGCTTC
ACCCCGGCCGGCGCGCCGAA

Product: LAO/AO transporter ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MRRPKRLPLERYVEGVLAGDRTILARAITVIESNLPSDGELAAHLLDALLPHTGQALRVGITGVPGVGKSTFVDALGMHL
IAERGENVAVLSVDPSSPISGGSILGDKTRMERLAVNERAFIRPSPSQGHLGGVARRTRETILLCEAAGYRNILVETVGV
GQSETAVRSMTDFFLLLMLAGAGDELQGVKRGIIEMLDGMAINKADGDNRVKAERARVEYAGALHLFPASADGWTPRVLT
CSAIAKEGISELWQMVLDHRALLEGNGCLARLRNLQALHWMNELTMLGLEDLFRANQAVARRLPLLREEVRRGRITPFAA
SRELLALFQLQSEIL

Sequences:

>Translated_335_residues
MRRPKRLPLERYVEGVLAGDRTILARAITVIESNLPSDGELAAHLLDALLPHTGQALRVGITGVPGVGKSTFVDALGMHL
IAERGENVAVLSVDPSSPISGGSILGDKTRMERLAVNERAFIRPSPSQGHLGGVARRTRETILLCEAAGYRNILVETVGV
GQSETAVRSMTDFFLLLMLAGAGDELQGVKRGIIEMLDGMAINKADGDNRVKAERARVEYAGALHLFPASADGWTPRVLT
CSAIAKEGISELWQMVLDHRALLEGNGCLARLRNLQALHWMNELTMLGLEDLFRANQAVARRLPLLREEVRRGRITPFAA
SRELLALFQLQSEIL
>Mature_335_residues
MRRPKRLPLERYVEGVLAGDRTILARAITVIESNLPSDGELAAHLLDALLPHTGQALRVGITGVPGVGKSTFVDALGMHL
IAERGENVAVLSVDPSSPISGGSILGDKTRMERLAVNERAFIRPSPSQGHLGGVARRTRETILLCEAAGYRNILVETVGV
GQSETAVRSMTDFFLLLMLAGAGDELQGVKRGIIEMLDGMAINKADGDNRVKAERARVEYAGALHLFPASADGWTPRVLT
CSAIAKEGISELWQMVLDHRALLEGNGCLARLRNLQALHWMNELTMLGLEDLFRANQAVARRLPLLREEVRRGRITPFAA
SRELLALFQLQSEIL

Specific function: Phosphorylates the AO and LAO periplasmic-binding proteins [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=331, Percent_Identity=46.5256797583082, Blast_Score=271, Evalue=7e-73,
Organism=Escherichia coli, GI1789285, Length=313, Percent_Identity=48.8817891373802, Blast_Score=301, Evalue=4e-83,
Organism=Caenorhabditis elegans, GI71994271, Length=330, Percent_Identity=40.6060606060606, Blast_Score=252, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71994275, Length=272, Percent_Identity=44.4852941176471, Blast_Score=239, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR016121 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 36474; Mature: 36474

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRPKRLPLERYVEGVLAGDRTILARAITVIESNLPSDGELAAHLLDALLPHTGQALRVG
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEE
ITGVPGVGKSTFVDALGMHLIAERGENVAVLSVDPSSPISGGSILGDKTRMERLAVNERA
CCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCE
FIRPSPSQGHLGGVARRTRETILLCEAAGYRNILVETVGVGQSETAVRSMTDFFLLLMLA
EECCCCCCCCCCHHHHHHHHEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GAGDELQGVKRGIIEMLDGMAINKADGDNRVKAERARVEYAGALHLFPASADGWTPRVLT
CCCHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCHHEE
CSAIAKEGISELWQMVLDHRALLEGNGCLARLRNLQALHWMNELTMLGLEDLFRANQAVA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLPLLREEVRRGRITPFAASRELLALFQLQSEIL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRPKRLPLERYVEGVLAGDRTILARAITVIESNLPSDGELAAHLLDALLPHTGQALRVG
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEEEE
ITGVPGVGKSTFVDALGMHLIAERGENVAVLSVDPSSPISGGSILGDKTRMERLAVNERA
CCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCCCE
FIRPSPSQGHLGGVARRTRETILLCEAAGYRNILVETVGVGQSETAVRSMTDFFLLLMLA
EECCCCCCCCCCHHHHHHHHEEEEEECCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
GAGDELQGVKRGIIEMLDGMAINKADGDNRVKAERARVEYAGALHLFPASADGWTPRVLT
CCCHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCHHEE
CSAIAKEGISELWQMVLDHRALLEGNGCLARLRNLQALHWMNELTMLGLEDLFRANQAVA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRLPLLREEVRRGRITPFAASRELLALFQLQSEIL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9733684; 9278503 [H]