Click here to switch to the map view.

The map label for this gene is mntH1 [H]

Identifier: 116625964

GI number: 116625964

Start: 8693444

End: 8694685

Strand: Reverse

Name: mntH1 [H]

Synonym: Acid_6922

Alternate gene names: 116625964

Gene position: 8694685-8693444 (Counterclockwise)

Preceding gene: 116625978

Following gene: 116625963

Centisome position: 87.25

GC content: 56.6

Gene sequence:

>1242_bases
ATGCGAAAGCTGCTTGGAATCACGCTTGGAATCATGACGGCGTTAGGCGGCTTCGTTGATTTCGGGCAGATCGTATTCAC
GCTGCAGGCAGGAGCCTCCTTCCGTTACGCGTTACTCTGGCCAGTTCTCCTCGGTACGTTAGCGATTATTGTCTACATGG
AGATGTGCGGGCGAATTGCCGTGGTCGCCCGGGAACCGGTATTCGCTATTGTGCGGGACCGCCTGGGCAAGACTTTGGGT
TTGGGGGTACTTCTTGCATCGAATCTATTGAACCTCATAACCTGTGCCGCCGAGCTTGGCGGAATCGCCATCATTTTGCA
TTTGCTGACTGGCTGGCCGGAGAAGCTGATGTTAGCGGGCGCGGCTGTGGCGCTCGGTTTGATCGTCGCACTCTTGCGTT
TTGAGTGGATCGAGCGGCTTTTCGGTCTGGCCGGCGTGGCCATGGTAGTTGTCGCTGTCTCTGCCTGGAAGTTGGGCCCG
GACTGGAAGGCGCTCGCGCGTGGGATTATTCCAAGCGTCTCCCTAGCAGATAGTCACGAAACGCTTCGGTACTGGTTTTT
CGCGGTCGGCATCTTCAGCGCCATGCTCATGGAATATGAAGTCCATTTCTATTCGTCCGGGGCATTAGAGGAGGATTGGA
GCGAAGCGGACCTGGCCGAGAATTTCCTGGTCGCAAGCTGCGGTTCGGTTCTGGGCGCGTTGCTGACGGCGGCGCTCCTG
GCAATCGGCGCCATGGTCTTCTTCCCGGCGCATAGCTTTCCGGAGCACCTAACCGCCGCTGTCAGCGGCATTGCCTCGCC
ACTCGGGAAGACAGGATATTTGTTTGTGCTTTTGGGAACGCTCGCCTGCCTGGCCGGCGCGAGCGTAGAGACGATGTTGT
CCGGAGGTTACAACCTCTGTCAGTTTTATGACCTGCCTTGGGGAAAAAATCTGAGAGCGCGAGAGGTTCCTGCTTTCGCC
GTCTCCTGGATTGGCACGTTAGTCGTCGCCGCTCTTCTCGTATTTTCCGGATTTGACCCGCTCACACTGGTGAATATCTC
GGTTGTGTTCGGCATGGTGGTGATGCCGTTTACGTACTATCCGATAATACGGGTCGCAATGGACAGGCACATCATGAAAC
GCCACGTGAATTCCCGGACAAACACCGCACTGGGAGTTTTGTTTCTCGTCTTGATCACGGTTGCGGCGCTCGCCGCCATT
CCTCTGATGATTCTTACGGACTCGGGCCAACCTCGACACTGA

Upstream 100 bases:

>100_bases
AACGACTTCGCGAACATCGTCGCCGTCAAAGAAGTCCACTGATATCCTGAAGCTAACGCTGGGGAATCCCCGGTAAACTT
CGGTAGTCGAAGCTCTCGAC

Downstream 100 bases:

>100_bases
GATTTCACCTCAGCATTATCTAACGTGAGAGCGCACTGAACATAACAGTGGCCTGCCGGTTGCTCCGATGAAAATGTGCG
TCGGCCGACCGCAATCAACC

Product: natural resistance-associated macrophage protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MRKLLGITLGIMTALGGFVDFGQIVFTLQAGASFRYALLWPVLLGTLAIIVYMEMCGRIAVVAREPVFAIVRDRLGKTLG
LGVLLASNLLNLITCAAELGGIAIILHLLTGWPEKLMLAGAAVALGLIVALLRFEWIERLFGLAGVAMVVVAVSAWKLGP
DWKALARGIIPSVSLADSHETLRYWFFAVGIFSAMLMEYEVHFYSSGALEEDWSEADLAENFLVASCGSVLGALLTAALL
AIGAMVFFPAHSFPEHLTAAVSGIASPLGKTGYLFVLLGTLACLAGASVETMLSGGYNLCQFYDLPWGKNLRAREVPAFA
VSWIGTLVVAALLVFSGFDPLTLVNISVVFGMVVMPFTYYPIIRVAMDRHIMKRHVNSRTNTALGVLFLVLITVAALAAI
PLMILTDSGQPRH

Sequences:

>Translated_413_residues
MRKLLGITLGIMTALGGFVDFGQIVFTLQAGASFRYALLWPVLLGTLAIIVYMEMCGRIAVVAREPVFAIVRDRLGKTLG
LGVLLASNLLNLITCAAELGGIAIILHLLTGWPEKLMLAGAAVALGLIVALLRFEWIERLFGLAGVAMVVVAVSAWKLGP
DWKALARGIIPSVSLADSHETLRYWFFAVGIFSAMLMEYEVHFYSSGALEEDWSEADLAENFLVASCGSVLGALLTAALL
AIGAMVFFPAHSFPEHLTAAVSGIASPLGKTGYLFVLLGTLACLAGASVETMLSGGYNLCQFYDLPWGKNLRAREVPAFA
VSWIGTLVVAALLVFSGFDPLTLVNISVVFGMVVMPFTYYPIIRVAMDRHIMKRHVNSRTNTALGVLFLVLITVAALAAI
PLMILTDSGQPRH
>Mature_413_residues
MRKLLGITLGIMTALGGFVDFGQIVFTLQAGASFRYALLWPVLLGTLAIIVYMEMCGRIAVVAREPVFAIVRDRLGKTLG
LGVLLASNLLNLITCAAELGGIAIILHLLTGWPEKLMLAGAAVALGLIVALLRFEWIERLFGLAGVAMVVVAVSAWKLGP
DWKALARGIIPSVSLADSHETLRYWFFAVGIFSAMLMEYEVHFYSSGALEEDWSEADLAENFLVASCGSVLGALLTAALL
AIGAMVFFPAHSFPEHLTAAVSGIASPLGKTGYLFVLLGTLACLAGASVETMLSGGYNLCQFYDLPWGKNLRAREVPAFA
VSWIGTLVVAALLVFSGFDPLTLVNISVVFGMVVMPFTYYPIIRVAMDRHIMKRHVNSRTNTALGVLFLVLITVAALAAI
PLMILTDSGQPRH

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 44320; Mature: 44320

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLLGITLGIMTALGGFVDFGQIVFTLQAGASFRYALLWPVLLGTLAIIVYMEMCGRIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEE
VVAREPVFAIVRDRLGKTLGLGVLLASNLLNLITCAAELGGIAIILHLLTGWPEKLMLAG
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AAVALGLIVALLRFEWIERLFGLAGVAMVVVAVSAWKLGPDWKALARGIIPSVSLADSHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHH
TLRYWFFAVGIFSAMLMEYEVHFYSSGALEEDWSEADLAENFLVASCGSVLGALLTAALL
HHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGAMVFFPAHSFPEHLTAAVSGIASPLGKTGYLFVLLGTLACLAGASVETMLSGGYNLC
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCC
QFYDLPWGKNLRAREVPAFAVSWIGTLVVAALLVFSGFDPLTLVNISVVFGMVVMPFTYY
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
PIIRVAMDRHIMKRHVNSRTNTALGVLFLVLITVAALAAIPLMILTDSGQPRH
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCC
>Mature Secondary Structure
MRKLLGITLGIMTALGGFVDFGQIVFTLQAGASFRYALLWPVLLGTLAIIVYMEMCGRIA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEE
VVAREPVFAIVRDRLGKTLGLGVLLASNLLNLITCAAELGGIAIILHLLTGWPEKLMLAG
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AAVALGLIVALLRFEWIERLFGLAGVAMVVVAVSAWKLGPDWKALARGIIPSVSLADSHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHH
TLRYWFFAVGIFSAMLMEYEVHFYSSGALEEDWSEADLAENFLVASCGSVLGALLTAALL
HHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AIGAMVFFPAHSFPEHLTAAVSGIASPLGKTGYLFVLLGTLACLAGASVETMLSGGYNLC
HHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCC
QFYDLPWGKNLRAREVPAFAVSWIGTLVVAALLVFSGFDPLTLVNISVVFGMVVMPFTYY
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
PIIRVAMDRHIMKRHVNSRTNTALGVLFLVLITVAALAAIPLMILTDSGQPRH
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10844693; 10984043 [H]