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The map label for this gene is ctaC [H]

Identifier: 116625951

GI number: 116625951

Start: 8680118

End: 8681086

Strand: Reverse

Name: ctaC [H]

Synonym: Acid_6909

Alternate gene names: 116625951

Gene position: 8681086-8680118 (Counterclockwise)

Preceding gene: 116625952

Following gene: 116625950

Centisome position: 87.11

GC content: 57.79

Gene sequence:

>969_bases
ATGAACCAGTCGATGTGGCACGCCTCCGGACCCAATGCTGCGTACGTTCGGGAACTCGGGATCTTCTTCGGCCTTCTACT
GGGGATTATTTTTGTAATTGTTGTGGGGCTCGCGCTTTTCTCCTTGAGACGCCGGCATCGCGGCATCGAGCAGGAAGCCC
TCGAGGGGTCGCATCAGGCTTCGGAGAGAACCGACGGCCGGCTTCGGATGGTGGTTGGCATCGCAACCGCGCTCACCGTT
TCGATACTGTTTGGCCTTACCATCGTCAGCGTTTCTGTCGGTAAGAGCATCTCAGCCTCGGCTGCTCCGGCGAACAGCCT
GCTTATCGAAGTGACGGGTGCCCAATGGTGGTGGAAGATTCGGTATGCGAATGATGATCCCAGCCGCATCATCGAAACCG
CCAACGAAATCCACATTCCCACTGGAAGGCCCGTCGCGATTCGTGGAACTGCCGACGACGTCATTCATAGTTTCTGGGTG
CCAAGTCTTCAAGGAAAACGCGACCTGATTCCGGGGCGTACGACCTTGGAATGGATGCAGGCGGACCAGCCCGGCGAATA
TCGCGGCCAGTGTGCGGAATTCTGCGGTCTTCAGCATGCCCATATGGCGTTCTGGGTGATCGCGGAACCACCGCAACAAT
TCAACCATTGGATGGACCATCAGCTTCAGCCGGCCATTGAGCCAGCGGATGAAGATACGAAACGGGGAAAGGAAATATTC
CTACAGAGCGCCTGCATTCTCTGTCATGCGATTCGCGGAACCGATGCCAGCGCGCAGGCCGGGCCAGATCTGACCCATTT
CGGAAGCCGCAAGACGATCGCCGCGGGCACCCTTCCCAACAGTAAAGGGAACCTTGCCGGCTGGATCGCCGATCCGCAAA
ACATCAAACCCGGGACCCACATGGCCACAGTGCCGATTCGGCCAGCCGAGATGCAGCCCCTGATCGACTATTTGGAGAGC
CTGAAATGA

Upstream 100 bases:

>100_bases
TGAATAATCTGGAGCCGAAGGCTGCGACCCCTTCCCGTCCGGATACGCTCGAACAGAAGACGGACACAATTCTTCCAGAC
AAAGGGGGAGCCAACCATCC

Downstream 100 bases:

>100_bases
TACCGGCGGCCACAGAGCAGCACGCGTATGCGAATCTCGACATCCTGCGTCGAACGTGGAGCTCCAAACCCGGTCTATTA
GGCTGGCTGTCGGAGACCAA

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MNQSMWHASGPNAAYVRELGIFFGLLLGIIFVIVVGLALFSLRRRHRGIEQEALEGSHQASERTDGRLRMVVGIATALTV
SILFGLTIVSVSVGKSISASAAPANSLLIEVTGAQWWWKIRYANDDPSRIIETANEIHIPTGRPVAIRGTADDVIHSFWV
PSLQGKRDLIPGRTTLEWMQADQPGEYRGQCAEFCGLQHAHMAFWVIAEPPQQFNHWMDHQLQPAIEPADEDTKRGKEIF
LQSACILCHAIRGTDASAQAGPDLTHFGSRKTIAAGTLPNSKGNLAGWIADPQNIKPGTHMATVPIRPAEMQPLIDYLES
LK

Sequences:

>Translated_322_residues
MNQSMWHASGPNAAYVRELGIFFGLLLGIIFVIVVGLALFSLRRRHRGIEQEALEGSHQASERTDGRLRMVVGIATALTV
SILFGLTIVSVSVGKSISASAAPANSLLIEVTGAQWWWKIRYANDDPSRIIETANEIHIPTGRPVAIRGTADDVIHSFWV
PSLQGKRDLIPGRTTLEWMQADQPGEYRGQCAEFCGLQHAHMAFWVIAEPPQQFNHWMDHQLQPAIEPADEDTKRGKEIF
LQSACILCHAIRGTDASAQAGPDLTHFGSRKTIAAGTLPNSKGNLAGWIADPQNIKPGTHMATVPIRPAEMQPLIDYLES
LK
>Mature_322_residues
MNQSMWHASGPNAAYVRELGIFFGLLLGIIFVIVVGLALFSLRRRHRGIEQEALEGSHQASERTDGRLRMVVGIATALTV
SILFGLTIVSVSVGKSISASAAPANSLLIEVTGAQWWWKIRYANDDPSRIIETANEIHIPTGRPVAIRGTADDVIHSFWV
PSLQGKRDLIPGRTTLEWMQADQPGEYRGQCAEFCGLQHAHMAFWVIAEPPQQFNHWMDHQLQPAIEPADEDTKRGKEIF
LQSACILCHAIRGTDASAQAGPDLTHFGSRKTIAAGTLPNSKGNLAGWIADPQNIKPGTHMATVPIRPAEMQPLIDYLES
LK

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=114, Percent_Identity=34.2105263157895, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1786635, Length=197, Percent_Identity=26.9035532994924, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6226540, Length=138, Percent_Identity=28.9855072463768, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 35350; Mature: 35350

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00078 COX2 ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQSMWHASGPNAAYVRELGIFFGLLLGIIFVIVVGLALFSLRRRHRGIEQEALEGSHQA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHH
SERTDGRLRMVVGIATALTVSILFGLTIVSVSVGKSISASAAPANSLLIEVTGAQWWWKI
HHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEE
RYANDDPSRIIETANEIHIPTGRPVAIRGTADDVIHSFWVPSLQGKRDLIPGRTTLEWMQ
EECCCCHHHHHHHHHHEECCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
ADQPGEYRGQCAEFCGLQHAHMAFWVIAEPPQQFNHWMDHQLQPAIEPADEDTKRGKEIF
CCCCCHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
LQSACILCHAIRGTDASAQAGPDLTHFGSRKTIAAGTLPNSKGNLAGWIADPQNIKPGTH
HHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCEEEEECCCCCCCCCCE
MATVPIRPAEMQPLIDYLESLK
EEEECCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQSMWHASGPNAAYVRELGIFFGLLLGIIFVIVVGLALFSLRRRHRGIEQEALEGSHQA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHH
SERTDGRLRMVVGIATALTVSILFGLTIVSVSVGKSISASAAPANSLLIEVTGAQWWWKI
HHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCEEEEE
RYANDDPSRIIETANEIHIPTGRPVAIRGTADDVIHSFWVPSLQGKRDLIPGRTTLEWMQ
EECCCCHHHHHHHHHHEECCCCCCEEEECCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
ADQPGEYRGQCAEFCGLQHAHMAFWVIAEPPQQFNHWMDHQLQPAIEPADEDTKRGKEIF
CCCCCHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
LQSACILCHAIRGTDASAQAGPDLTHFGSRKTIAAGTLPNSKGNLAGWIADPQNIKPGTH
HHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCEEEEECCCCCCCCCCE
MATVPIRPAEMQPLIDYLESLK
EEEECCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]