Click here to switch to the map view.

The map label for this gene is rsbU [H]

Identifier: 116625652

GI number: 116625652

Start: 8281456

End: 8283945

Strand: Reverse

Name: rsbU [H]

Synonym: Acid_6601

Alternate gene names: 116625652

Gene position: 8283945-8281456 (Counterclockwise)

Preceding gene: 116625655

Following gene: 116625650

Centisome position: 83.13

GC content: 65.38

Gene sequence:

>2490_bases
ATGTCCAGGCAGTACCGTCTGCTGCTCGCCCTCTTCGTTGTGACGATCGCCTGCCAGGCAACCTTTACGATCGACGTGAT
TCGTACCCTGGCCGGTGATTATCCGGTTCAACCTTTTGCGCTCGGAGCTCCGTGGCCCACCATTCTGCGGCTTTCGCCGG
GCGCCTCCGAGGCCGGACTGCGACGCGGCGATCACGTGCTCGCCATCGAGGGCAGCGCACCCGCCGGCGAATCCGACCTG
GCGCGGGCGGTCCATGGCAAACACCCCGGAGGGCGGCTGGCGGTCACGGTTGAGCGCGACGGCCGGCCCCTCGAAATCCG
GGCGCCGATCGAGCCACATCGCACCTGGTGGAGCTTTGCCCTGATCACGCTGATCTTCATGCCCTGGCTTTCTATTTTGC
TGGGCTTCTGGGTGGCCGCCGTCCGGCCGCGCGACAGCCGCGCCTGGCTGGTGTTAGGGATTCTGGTCGGCCTCAGCCAG
CTGGTGCGTCCCGGCGTGATCGATCCGCGCGGATGGGCCGCGGATTTCGGCTTCCTCGCGCTGGTCTTCCGCCCCCTCGC
GGCGGTTGCGTGGGCAATCTGCATGATGCTTTTCGGCATCTATTTTCCGCAACGATGGGAGGTGGACCGGCGCCTGCCGT
GGGCCAAGTGGATCCTGATCGCGCCGCTCGCCCTGGAGGGAGTCTACGATGCCGCTCGCGACGTGGTGGCGAGTTCGAAC
TTCGCTGCCGCCGCCCAATGGCCGACCCTTCTGCCCGGCGCCCTCAACACCGCGCTGATCATGACGGCAGTCGGCATCTT
CTTCATGGCGCTGTCCCACAAATATCGCGATCCCGCCCTGGCTTCGGACGATAAACGCCGCCTCAAGCTGCTCTATTGGG
GATCCACCGTCGCGCTCGCCCCGTCTTTCCTGCTGATACTGTATTCGCTGGTTGTGCTCCACCGCGAAGCCGGCGAAAGC
GATGTGCTTGCGTACAGCATTATGGCGATGGCGATCTTTCCGGTGACCATGGCCTATGTGATCGTGGTGGGCCGCGCGCT
CGATGTGCGCATGATCGTGCGAACCGGCATGCAGTACGCGCTTGCCCGCGGCGGCATCAAAGTGATCCAGGCCGGTCTCG
TGATCACCACGGTTTTGCTACTGGTCTCCATGGCCGAGAGAGGCCACTTCTCGCGGCCCGCCCAGATGACGCAGATCGGG
CTGGCCGTCATCCTGGTGGTGCGCATCCGCGACCTGGGCGAGCGCCTGCGGCGCTGGGTGGATCGCCGCTTTTTCCGCGA
GGCCTACAACGCAGAACAAATTCTCAGCGAGCTTAGCGAACAGGTGCGCTCCATTCTCAACACTCACGAGCTGCTCGAAA
CCGTCGCGCGCAAAATCTCCGAATCGCTCCACGTGCGCCACATTGCCGTCGTGCTGCAGGAGGGCGGAGGCGCTTTCCGG
CCGGCGCTCGCTGCCGGGTACGACCTTCCCGCCGGCTACGAACTGCCGGACGGCGCGGCTTCGATCGCCCAACTGCGCCT
CACGCGCGCCCCCATCGACGCCATCACTTATAAGGATCTCGCGCCACTCGACGCGCAGCTCGTGCTCCCGCTTGCCTCGC
GTAAGGAATTACTCGGCTTCATCAGCCTGGGCCCCAAGAAATCCGAGGAGCCGTATTCTCCGGGCGACACCAACTTGCTG
CGAACCGTGGCCGCGCAGACCGGCCTCGCGCTGGAGAACAGCCGCCTTTCCGAAGCCTTCGCCGGCGAGGTGGCCAAGCG
CGAGACGCTGCATCGCGAAATCGAAATCGCCCGCGAAGTGCAGCAGCGCCTCTTCCCGCAGAGCCTGCCGCATGTGGCGG
CGCTCGAGTACGCCGGCCACTGCCGCCCGGCCAGCGGAGTCGGCGGAGACTACTACGATTTCCTGGCGCTCTCCAGCGGC
CGCCTCGGCCTCGCCATCGGCGATATTTCGGGGAAGGGAATTCCCGCCGCCCTGTTGATGGCCAGCCTCCAGGCTTCGGT
GCGCGGGCAATCGCTCGGCACCGGAGAAGACATCGCCGGCCTGATGACCAACGTCAACCAGCTGGTCTACGACGCGTCTC
CCGAGAACCGCTACGCCACTTTCTTTTACGCGCAGTTCGACCCGGCCACGCGCCGCCTGATCTACACCAACGGCGGTCAC
AATCCGCCGATGTTGCTGCGCGGAATGGAAGTGATCCTGCTTGAAATCGGTGGCCCACCGGTCGGACTCTTCCGGCCCGC
GGGCTACCAGCAGGCCGAGATTCAACTCGAGCCCGGCGACGTTCTGGTCTGCTATACGGATGGCATCAGCGAAGCCGAAA
ATCCGCTCGAAGACGAGTGGGGCGAGGCTGCGCTGATCGCCGCCGCCCGCAGTTGCCGCGAGCAGCCCGCCATGGAGATG
ATCACCCGCATTCTGGCCGCCGCCGACACCTTCGCCGCCGGCGCAGCCCAACACGACGATATGACTCTGGTCATCGCCCG
CGTGATTTGA

Upstream 100 bases:

>100_bases
TATTTCTAACTCGCGACATGGGCTCCTCCCATTGTACAGAGCGCAACTTCCTAAAGCCGCGCCCCGATCCGGCCGGCCCA
AATCTGATAGTGTGTTGAAA

Downstream 100 bases:

>100_bases
CTGGCCAAGGGCGCGTCAGTGTATGCCCCAGATATCCGTCATATCCTCCGCCGCCACATAAAACTGCGATGGGCCGGTGC
GCACGATCCATTGGCGATGA

Product: serine phosphatase

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 829; Mature: 828

Protein sequence:

>829_residues
MSRQYRLLLALFVVTIACQATFTIDVIRTLAGDYPVQPFALGAPWPTILRLSPGASEAGLRRGDHVLAIEGSAPAGESDL
ARAVHGKHPGGRLAVTVERDGRPLEIRAPIEPHRTWWSFALITLIFMPWLSILLGFWVAAVRPRDSRAWLVLGILVGLSQ
LVRPGVIDPRGWAADFGFLALVFRPLAAVAWAICMMLFGIYFPQRWEVDRRLPWAKWILIAPLALEGVYDAARDVVASSN
FAAAAQWPTLLPGALNTALIMTAVGIFFMALSHKYRDPALASDDKRRLKLLYWGSTVALAPSFLLILYSLVVLHREAGES
DVLAYSIMAMAIFPVTMAYVIVVGRALDVRMIVRTGMQYALARGGIKVIQAGLVITTVLLLVSMAERGHFSRPAQMTQIG
LAVILVVRIRDLGERLRRWVDRRFFREAYNAEQILSELSEQVRSILNTHELLETVARKISESLHVRHIAVVLQEGGGAFR
PALAAGYDLPAGYELPDGAASIAQLRLTRAPIDAITYKDLAPLDAQLVLPLASRKELLGFISLGPKKSEEPYSPGDTNLL
RTVAAQTGLALENSRLSEAFAGEVAKRETLHREIEIAREVQQRLFPQSLPHVAALEYAGHCRPASGVGGDYYDFLALSSG
RLGLAIGDISGKGIPAALLMASLQASVRGQSLGTGEDIAGLMTNVNQLVYDASPENRYATFFYAQFDPATRRLIYTNGGH
NPPMLLRGMEVILLEIGGPPVGLFRPAGYQQAEIQLEPGDVLVCYTDGISEAENPLEDEWGEAALIAAARSCREQPAMEM
ITRILAAADTFAAGAAQHDDMTLVIARVI

Sequences:

>Translated_829_residues
MSRQYRLLLALFVVTIACQATFTIDVIRTLAGDYPVQPFALGAPWPTILRLSPGASEAGLRRGDHVLAIEGSAPAGESDL
ARAVHGKHPGGRLAVTVERDGRPLEIRAPIEPHRTWWSFALITLIFMPWLSILLGFWVAAVRPRDSRAWLVLGILVGLSQ
LVRPGVIDPRGWAADFGFLALVFRPLAAVAWAICMMLFGIYFPQRWEVDRRLPWAKWILIAPLALEGVYDAARDVVASSN
FAAAAQWPTLLPGALNTALIMTAVGIFFMALSHKYRDPALASDDKRRLKLLYWGSTVALAPSFLLILYSLVVLHREAGES
DVLAYSIMAMAIFPVTMAYVIVVGRALDVRMIVRTGMQYALARGGIKVIQAGLVITTVLLLVSMAERGHFSRPAQMTQIG
LAVILVVRIRDLGERLRRWVDRRFFREAYNAEQILSELSEQVRSILNTHELLETVARKISESLHVRHIAVVLQEGGGAFR
PALAAGYDLPAGYELPDGAASIAQLRLTRAPIDAITYKDLAPLDAQLVLPLASRKELLGFISLGPKKSEEPYSPGDTNLL
RTVAAQTGLALENSRLSEAFAGEVAKRETLHREIEIAREVQQRLFPQSLPHVAALEYAGHCRPASGVGGDYYDFLALSSG
RLGLAIGDISGKGIPAALLMASLQASVRGQSLGTGEDIAGLMTNVNQLVYDASPENRYATFFYAQFDPATRRLIYTNGGH
NPPMLLRGMEVILLEIGGPPVGLFRPAGYQQAEIQLEPGDVLVCYTDGISEAENPLEDEWGEAALIAAARSCREQPAMEM
ITRILAAADTFAAGAAQHDDMTLVIARVI
>Mature_828_residues
SRQYRLLLALFVVTIACQATFTIDVIRTLAGDYPVQPFALGAPWPTILRLSPGASEAGLRRGDHVLAIEGSAPAGESDLA
RAVHGKHPGGRLAVTVERDGRPLEIRAPIEPHRTWWSFALITLIFMPWLSILLGFWVAAVRPRDSRAWLVLGILVGLSQL
VRPGVIDPRGWAADFGFLALVFRPLAAVAWAICMMLFGIYFPQRWEVDRRLPWAKWILIAPLALEGVYDAARDVVASSNF
AAAAQWPTLLPGALNTALIMTAVGIFFMALSHKYRDPALASDDKRRLKLLYWGSTVALAPSFLLILYSLVVLHREAGESD
VLAYSIMAMAIFPVTMAYVIVVGRALDVRMIVRTGMQYALARGGIKVIQAGLVITTVLLLVSMAERGHFSRPAQMTQIGL
AVILVVRIRDLGERLRRWVDRRFFREAYNAEQILSELSEQVRSILNTHELLETVARKISESLHVRHIAVVLQEGGGAFRP
ALAAGYDLPAGYELPDGAASIAQLRLTRAPIDAITYKDLAPLDAQLVLPLASRKELLGFISLGPKKSEEPYSPGDTNLLR
TVAAQTGLALENSRLSEAFAGEVAKRETLHREIEIAREVQQRLFPQSLPHVAALEYAGHCRPASGVGGDYYDFLALSSGR
LGLAIGDISGKGIPAALLMASLQASVRGQSLGTGEDIAGLMTNVNQLVYDASPENRYATFFYAQFDPATRRLIYTNGGHN
PPMLLRGMEVILLEIGGPPVGLFRPAGYQQAEIQLEPGDVLVCYTDGISEAENPLEDEWGEAALIAAARSCREQPAMEMI
TRILAAADTFAAGAAQHDDMTLVIARVI

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 90462; Mature: 90331

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQYRLLLALFVVTIACQATFTIDVIRTLAGDYPVQPFALGAPWPTILRLSPGASEAGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCEEEEECCCCCHHHC
RRGDHVLAIEGSAPAGESDLARAVHGKHPGGRLAVTVERDGRPLEIRAPIEPHRTWWSFA
CCCCEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHH
LITLIFMPWLSILLGFWVAAVRPRDSRAWLVLGILVGLSQLVRPGVIDPRGWAADFGFLA
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LVFRPLAAVAWAICMMLFGIYFPQRWEVDRRLPWAKWILIAPLALEGVYDAARDVVASSN
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
FAAAAQWPTLLPGALNTALIMTAVGIFFMALSHKYRDPALASDDKRRLKLLYWGSTVALA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHH
PSFLLILYSLVVLHREAGESDVLAYSIMAMAIFPVTMAYVIVVGRALDVRMIVRTGMQYA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LARGGIKVIQAGLVITTVLLLVSMAERGHFSRPAQMTQIGLAVILVVRIRDLGERLRRWV
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRRFFREAYNAEQILSELSEQVRSILNTHELLETVARKISESLHVRHIAVVLQEGGGAFR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCC
PALAAGYDLPAGYELPDGAASIAQLRLTRAPIDAITYKDLAPLDAQLVLPLASRKELLGF
CHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCCCCEEECHHHHHHHHHH
ISLGPKKSEEPYSPGDTNLLRTVAAQTGLALENSRLSEAFAGEVAKRETLHREIEIAREV
HHCCCCCCCCCCCCCCHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QQRLFPQSLPHVAALEYAGHCRPASGVGGDYYDFLALSSGRLGLAIGDISGKGIPAALLM
HHHHCHHCCCCHHHHHHCCCCCCCCCCCCCHHHHHEECCCCCEEEEECCCCCCCHHHHHH
ASLQASVRGQSLGTGEDIAGLMTNVNQLVYDASPENRYATFFYAQFDPATRRLIYTNGGH
HHHHHHHCCCCCCCCHHHHHHHHHHHHHEECCCCCCCEEEEEEEECCCCCCEEEEECCCC
NPPMLLRGMEVILLEIGGPPVGLFRPAGYQQAEIQLEPGDVLVCYTDGISEAENPLEDEW
CCCHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHH
GEAALIAAARSCREQPAMEMITRILAAADTFAAGAAQHDDMTLVIARVI
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECC
>Mature Secondary Structure 
SRQYRLLLALFVVTIACQATFTIDVIRTLAGDYPVQPFALGAPWPTILRLSPGASEAGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCEEEEECCCCCHHHC
RRGDHVLAIEGSAPAGESDLARAVHGKHPGGRLAVTVERDGRPLEIRAPIEPHRTWWSFA
CCCCEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHHHH
LITLIFMPWLSILLGFWVAAVRPRDSRAWLVLGILVGLSQLVRPGVIDPRGWAADFGFLA
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LVFRPLAAVAWAICMMLFGIYFPQRWEVDRRLPWAKWILIAPLALEGVYDAARDVVASSN
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
FAAAAQWPTLLPGALNTALIMTAVGIFFMALSHKYRDPALASDDKRRLKLLYWGSTVALA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHH
PSFLLILYSLVVLHREAGESDVLAYSIMAMAIFPVTMAYVIVVGRALDVRMIVRTGMQYA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
LARGGIKVIQAGLVITTVLLLVSMAERGHFSRPAQMTQIGLAVILVVRIRDLGERLRRWV
HHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRRFFREAYNAEQILSELSEQVRSILNTHELLETVARKISESLHVRHIAVVLQEGGGAFR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCC
PALAAGYDLPAGYELPDGAASIAQLRLTRAPIDAITYKDLAPLDAQLVLPLASRKELLGF
CHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCCCCEEECHHHHHHHHHH
ISLGPKKSEEPYSPGDTNLLRTVAAQTGLALENSRLSEAFAGEVAKRETLHREIEIAREV
HHCCCCCCCCCCCCCCHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QQRLFPQSLPHVAALEYAGHCRPASGVGGDYYDFLALSSGRLGLAIGDISGKGIPAALLM
HHHHCHHCCCCHHHHHHCCCCCCCCCCCCCHHHHHEECCCCCEEEEECCCCCCCHHHHHH
ASLQASVRGQSLGTGEDIAGLMTNVNQLVYDASPENRYATFFYAQFDPATRRLIYTNGGH
HHHHHHHCCCCCCCCHHHHHHHHHHHHHEECCCCCCCEEEEEEEECCCCCCEEEEECCCC
NPPMLLRGMEVILLEIGGPPVGLFRPAGYQQAEIQLEPGDVLVCYTDGISEAENPLEDEW
CCCHHHCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHH
GEAALIAAARSCREQPAMEMITRILAAADTFAAGAAQHDDMTLVIARVI
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]