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The map label for this gene is nahA [H]

Identifier: 116625620

GI number: 116625620

Start: 8231414

End: 8233405

Strand: Direct

Name: nahA [H]

Synonym: Acid_6569

Alternate gene names: 116625620

Gene position: 8231414-8233405 (Clockwise)

Preceding gene: 116625618

Following gene: 116625621

Centisome position: 82.6

GC content: 65.56

Gene sequence:

>1992_bases
ATGGAGGTGATGCTTCGATATGCGCTCTTTTGCGCCCTTCTTTCCAGTGCTCATGCGGCGGCGCCCGCGTTGATGCCGCT
GCCCGCCACGATGCGGCCGGCCGCTGGCAAACTGACGATCGATTCGAGTTTCAAGGCGACGCTTTCCGGCGCGGCTGATG
CGCACCTGGAGGCGGCGATCGCGCGCTTCACGGCGCAACTCTCGCGGCAGACCGGGATCCCTATGTTCGCGAACAAGGGC
GCAGCAGCCAGGCTGCGCGTCGAATGCGCGTCCGCCGGCGGGGAGGTTCCCAAGCTCGGCGACAACGAGGCGTACACGTT
GGACGTCACGGCGGATGGAGCCACACTCAAAGCGCCCGAGCGCGCCGGCGTGCTGCACGGCCTGGCAACCTTCGCACAAC
TGGTAATGCTGGGCGATCAGGGTTACGAAGTACCGGCCGTCCACATTGAAGATCGACCGCGGTTTCCGTGGCGCGGACTG
ATGCTGGATTCGGCGCGGCACTTCATGCCGCTTGCGGTGGTGAAACGCAACCTGGACGCGATGGCGGCCGTGAAGCTCAA
CGTCTTCCACTGGCACCTTTCCGAGGACCAGGGCTTCCGCGTGGAGAGCAAGCGCTATCCCAAGCTGCAGGAGAAGGGGT
CCGACGGCCTCTTCTACACGCAGTCCGAGATCCGCGACATTGTGAGCTACGCGAGGGATCGCGGCATCCGCGTGGTGCCG
GAGTTCGACATCCCGGGACACACCACGGCATGGATGGTGGGCTACCCCGAATTGGGTACCGTTCCCGGGCCGTATGAAAT
CGGGCGCAAGTGGGGCGTGTACGAAAACGCGCTGGATCCGAGCCGCGAAGAGACCTACACTTTCCTGGATAACTTCTTCG
AAGAAATCACGCCGCTCTTCGCCGACCTTTACTTCCACATCGGCGGCGACGAAGTAGTGGCCAGGCAGTGGAACGCGTCG
GCGCGCGTTCAGGCGTGGGCCAAGGAACACAACCTGAAAGACGCGCACGCGATCCAGGCGTACTTCAACACGCGCGTGCA
GAAACTGCTGCAGAAGCGCGGCAAGGTGCTGATCGGCTGGGACGAGGTACTGCATCCCGACCTGCCGAAGGACATTGTGG
TGCAGTCCTGGCGCGGGCAGAAATCGCTGGCCGAAGCGGCGACTAAAGGCTATCGCGGGATTCTCTCGTGGGGCTATTAT
CTGGATCACCTGAGCCCGGCGAAGTTCCACTATGGCGTGGACCCGATGTCGAGCGACGCCGACAAACTAGCGCCGGAGCA
GGCCTCGCGCATCCTCGGAGGCGAAGCATGCATGTGGGCCGAATACACGACGTCGGAAACCGTGGATTCGCGGATCTGGC
CGCGCGCGGCGGTGATCGCGGAGCGCTTGTGGTCGCCCGCCGCGACTGTGGATGTGGAATCGATGTACACGCGGATGGAA
GCCGTCAGCCGCGAGCTGGAATGGACGGGCGTGCAGCATCGCGCCAATTACGCGCCCATGCTGGACCGCATGACGGGCGG
CGCTCCGGCGGAGCCCTTGCGCATACTGGCAGACGCTGTGGAGGGCCTGGGCCTGAGTCCCCGAGCGCGAGTCGCGAAAT
ACACCAGCCTGACGCCGATGAACCGTTTGGCCGATGCCGCGCGCCCCGAGAGCGAGAGCGTGCACGCGCTCGAACTGGCG
GCCGCCAAGGTGGCTGCCGATCCCAACGGCAGCACGGCGGAGGCCGCGGCGCTGCGCACTGCGTTCACGCGGTGGGCAGC
CAACGACGCGCGCTTCCAGGAACTCGCGGCCGGCAATCCGCTGCTCGCGGAATTGAAGCCGCTATCAAAGGATCTGGCCG
CGCTCGGCAACGCCGGTCTGGCGCTGCTGGATGGCAGGCCGGCCCCCGCCGGATTCGCCGCCGAGTTGACGCGAATGGAG
CGGCCCCTTGCCGAGGTCTCGCTCGCGGCGACGCGCCCGGTGAAGATCCTGCTGAACGCCGGCAGGAAGTAG

Upstream 100 bases:

>100_bases
CCGGTAAGGCGGCAAGCGCAAATTTTGCGACATCGCGTCTGGTGTATTGCATGGTGACCTCGGGTGAAAGGCAATCGTAA
CATGTGGAACTTTTCGTAGT

Downstream 100 bases:

>100_bases
GCCTAACCTTCCCACCCGGATTGCGTCGGAGTAGGAATGCGGCAGAACCTGCGATTCGCGCTCCGGATGATGATCAAGAG
CCCTGGCTTCACCGCCGTCG

Product: beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 663; Mature: 663

Protein sequence:

>663_residues
MEVMLRYALFCALLSSAHAAAPALMPLPATMRPAAGKLTIDSSFKATLSGAADAHLEAAIARFTAQLSRQTGIPMFANKG
AAARLRVECASAGGEVPKLGDNEAYTLDVTADGATLKAPERAGVLHGLATFAQLVMLGDQGYEVPAVHIEDRPRFPWRGL
MLDSARHFMPLAVVKRNLDAMAAVKLNVFHWHLSEDQGFRVESKRYPKLQEKGSDGLFYTQSEIRDIVSYARDRGIRVVP
EFDIPGHTTAWMVGYPELGTVPGPYEIGRKWGVYENALDPSREETYTFLDNFFEEITPLFADLYFHIGGDEVVARQWNAS
ARVQAWAKEHNLKDAHAIQAYFNTRVQKLLQKRGKVLIGWDEVLHPDLPKDIVVQSWRGQKSLAEAATKGYRGILSWGYY
LDHLSPAKFHYGVDPMSSDADKLAPEQASRILGGEACMWAEYTTSETVDSRIWPRAAVIAERLWSPAATVDVESMYTRME
AVSRELEWTGVQHRANYAPMLDRMTGGAPAEPLRILADAVEGLGLSPRARVAKYTSLTPMNRLADAARPESESVHALELA
AAKVAADPNGSTAEAAALRTAFTRWAANDARFQELAAGNPLLAELKPLSKDLAALGNAGLALLDGRPAPAGFAAELTRME
RPLAEVSLAATRPVKILLNAGRK

Sequences:

>Translated_663_residues
MEVMLRYALFCALLSSAHAAAPALMPLPATMRPAAGKLTIDSSFKATLSGAADAHLEAAIARFTAQLSRQTGIPMFANKG
AAARLRVECASAGGEVPKLGDNEAYTLDVTADGATLKAPERAGVLHGLATFAQLVMLGDQGYEVPAVHIEDRPRFPWRGL
MLDSARHFMPLAVVKRNLDAMAAVKLNVFHWHLSEDQGFRVESKRYPKLQEKGSDGLFYTQSEIRDIVSYARDRGIRVVP
EFDIPGHTTAWMVGYPELGTVPGPYEIGRKWGVYENALDPSREETYTFLDNFFEEITPLFADLYFHIGGDEVVARQWNAS
ARVQAWAKEHNLKDAHAIQAYFNTRVQKLLQKRGKVLIGWDEVLHPDLPKDIVVQSWRGQKSLAEAATKGYRGILSWGYY
LDHLSPAKFHYGVDPMSSDADKLAPEQASRILGGEACMWAEYTTSETVDSRIWPRAAVIAERLWSPAATVDVESMYTRME
AVSRELEWTGVQHRANYAPMLDRMTGGAPAEPLRILADAVEGLGLSPRARVAKYTSLTPMNRLADAARPESESVHALELA
AAKVAADPNGSTAEAAALRTAFTRWAANDARFQELAAGNPLLAELKPLSKDLAALGNAGLALLDGRPAPAGFAAELTRME
RPLAEVSLAATRPVKILLNAGRK
>Mature_663_residues
MEVMLRYALFCALLSSAHAAAPALMPLPATMRPAAGKLTIDSSFKATLSGAADAHLEAAIARFTAQLSRQTGIPMFANKG
AAARLRVECASAGGEVPKLGDNEAYTLDVTADGATLKAPERAGVLHGLATFAQLVMLGDQGYEVPAVHIEDRPRFPWRGL
MLDSARHFMPLAVVKRNLDAMAAVKLNVFHWHLSEDQGFRVESKRYPKLQEKGSDGLFYTQSEIRDIVSYARDRGIRVVP
EFDIPGHTTAWMVGYPELGTVPGPYEIGRKWGVYENALDPSREETYTFLDNFFEEITPLFADLYFHIGGDEVVARQWNAS
ARVQAWAKEHNLKDAHAIQAYFNTRVQKLLQKRGKVLIGWDEVLHPDLPKDIVVQSWRGQKSLAEAATKGYRGILSWGYY
LDHLSPAKFHYGVDPMSSDADKLAPEQASRILGGEACMWAEYTTSETVDSRIWPRAAVIAERLWSPAATVDVESMYTRME
AVSRELEWTGVQHRANYAPMLDRMTGGAPAEPLRILADAVEGLGLSPRARVAKYTSLTPMNRLADAARPESESVHALELA
AAKVAADPNGSTAEAAALRTAFTRWAANDARFQELAAGNPLLAELKPLSKDLAALGNAGLALLDGRPAPAGFAAELTRME
RPLAEVSLAATRPVKILLNAGRK

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI189181666, Length=425, Percent_Identity=36.9411764705882, Blast_Score=273, Evalue=5e-73,
Organism=Homo sapiens, GI4504373, Length=491, Percent_Identity=32.9938900203666, Blast_Score=258, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17569815, Length=448, Percent_Identity=30.8035714285714, Blast_Score=222, Evalue=6e-58,
Organism=Drosophila melanogaster, GI24657468, Length=421, Percent_Identity=31.5914489311164, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI17647501, Length=421, Percent_Identity=31.5914489311164, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI281365639, Length=518, Percent_Identity=29.9227799227799, Blast_Score=189, Evalue=6e-48,
Organism=Drosophila melanogaster, GI24657474, Length=518, Percent_Identity=29.9227799227799, Blast_Score=189, Evalue=6e-48,
Organism=Drosophila melanogaster, GI17933586, Length=406, Percent_Identity=32.0197044334975, Blast_Score=172, Evalue=7e-43,
Organism=Drosophila melanogaster, GI24653074, Length=436, Percent_Identity=28.2110091743119, Blast_Score=163, Evalue=3e-40,
Organism=Drosophila melanogaster, GI45551090, Length=436, Percent_Identity=28.2110091743119, Blast_Score=163, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 72509; Mature: 72509

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVMLRYALFCALLSSAHAAAPALMPLPATMRPAAGKLTIDSSFKATLSGAADAHLEAAI
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCHHHHCCCCHHHHHHHH
ARFTAQLSRQTGIPMFANKGAAARLRVECASAGGEVPKLGDNEAYTLDVTADGATLKAPE
HHHHHHHHHHCCCCEEECCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEECCCCEECCCH
RAGVLHGLATFAQLVMLGDQGYEVPAVHIEDRPRFPWRGLMLDSARHFMPLAVVKRNLDA
HHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHCHHHHHHHHHHHHCCHH
MAAVKLNVFHWHLSEDQGFRVESKRYPKLQEKGSDGLFYTQSEIRDIVSYARDRGIRVVP
HEEEEEEEEEEEECCCCCCEECCCCCCCHHHCCCCCEEEEHHHHHHHHHHHHCCCCEEEE
EFDIPGHTTAWMVGYPELGTVPGPYEIGRKWGVYENALDPSREETYTFLDNFFEEITPLF
CCCCCCCCEEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ADLYFHIGGDEVVARQWNASARVQAWAKEHNLKDAHAIQAYFNTRVQKLLQKRGKVLIGW
HHHHHCCCCCCEEHECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEH
DEVLHPDLPKDIVVQSWRGQKSLAEAATKGYRGILSWGYYLDHLSPAKFHYGVDPMSSDA
HHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCH
DKLAPEQASRILGGEACMWAEYTTSETVDSRIWPRAAVIAERLWSPAATVDVESMYTRME
HHCCHHHHHHHHCCCEEEEEECCCCHHHHHHHCHHHHHHHHHHCCCCCCEEHHHHHHHHH
AVSRELEWTGVQHRANYAPMLDRMTGGAPAEPLRILADAVEGLGLSPRARVAKYTSLTPM
HHHHHHHHCCCHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHH
NRLADAARPESESVHALELAAAKVAADPNGSTAEAAALRTAFTRWAANDARFQELAAGNP
HHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
LLAELKPLSKDLAALGNAGLALLDGRPAPAGFAAELTRMERPLAEVSLAATRPVKILLNA
HHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCHHHHHHHCCCCEEEEECC
GRK
CCC
>Mature Secondary Structure
MEVMLRYALFCALLSSAHAAAPALMPLPATMRPAAGKLTIDSSFKATLSGAADAHLEAAI
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCHHHHCCCCHHHHHHHH
ARFTAQLSRQTGIPMFANKGAAARLRVECASAGGEVPKLGDNEAYTLDVTADGATLKAPE
HHHHHHHHHHCCCCEEECCCCCEEEEEEEECCCCCCCCCCCCCEEEEEEECCCCEECCCH
RAGVLHGLATFAQLVMLGDQGYEVPAVHIEDRPRFPWRGLMLDSARHFMPLAVVKRNLDA
HHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCHHHHCHHHHHHHHHHHHCCHH
MAAVKLNVFHWHLSEDQGFRVESKRYPKLQEKGSDGLFYTQSEIRDIVSYARDRGIRVVP
HEEEEEEEEEEEECCCCCCEECCCCCCCHHHCCCCCEEEEHHHHHHHHHHHHCCCCEEEE
EFDIPGHTTAWMVGYPELGTVPGPYEIGRKWGVYENALDPSREETYTFLDNFFEEITPLF
CCCCCCCCEEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ADLYFHIGGDEVVARQWNASARVQAWAKEHNLKDAHAIQAYFNTRVQKLLQKRGKVLIGW
HHHHHCCCCCCEEHECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEH
DEVLHPDLPKDIVVQSWRGQKSLAEAATKGYRGILSWGYYLDHLSPAKFHYGVDPMSSDA
HHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCH
DKLAPEQASRILGGEACMWAEYTTSETVDSRIWPRAAVIAERLWSPAATVDVESMYTRME
HHCCHHHHHHHHCCCEEEEEECCCCHHHHHHHCHHHHHHHHHHCCCCCCEEHHHHHHHHH
AVSRELEWTGVQHRANYAPMLDRMTGGAPAEPLRILADAVEGLGLSPRARVAKYTSLTPM
HHHHHHHHCCCHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHH
NRLADAARPESESVHALELAAAKVAADPNGSTAEAAALRTAFTRWAANDARFQELAAGNP
HHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCC
LLAELKPLSKDLAALGNAGLALLDGRPAPAGFAAELTRMERPLAEVSLAATRPVKILLNA
HHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCHHHHHHHCCCCEEEEECC
GRK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]