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The map label for this gene is hypE [H]

Identifier: 116625605

GI number: 116625605

Start: 8216454

End: 8217500

Strand: Direct

Name: hypE [H]

Synonym: Acid_6554

Alternate gene names: 116625605

Gene position: 8216454-8217500 (Clockwise)

Preceding gene: 116625604

Following gene: 116625606

Centisome position: 82.45

GC content: 64.28

Gene sequence:

>1047_bases
GTGGCGCAGAGCTTTGTGATGACGTGTCCGGTGCCGTTGACGCGGCATAAGACGATCGTGATGGGCCATGGGAGTGGGGG
GCGGCTGACGGCGCAGCTGGTGCGCGATCTCTTTCTGCCGGCCTTCGATAACCCGCTGCTACGGAAGCTGGACGATCAGG
CCGTGGTGGAGGCCGAAGGAACACGGATCGCATTTACGACGGACTCGTTCGTGGTGACGCCGCTCTTTTTCCCGGGGGGC
AATATCGGCCAATTGGCCGTGAATGGGACCGTGAACGACCTGGCGATGAGCGGGGCGATGCCGCTGGGGCTTTCGGCTGC
GTTCATTCTGGAAGAGGGACTGGTCATCGAGGAACTGGCCGCGGTGGCGGCAGCGATGGGACAGGCCGCGGCCGCAGCGG
GAGTTCCGATTGTGACGGGCGACACCAAAGTGGTGAACCGAAAGTCCGCCGATAAGCTCTTCGTGACCACGACCGGCATC
GGTGTGGTGCCGCGCGGGGTGGAGATCTCAGCCTCGAACGCGCGGCCCGGTGATGTAGTTCTGCTTAGCGGCACGATCGC
GGATCACGGGATGGCGGTGCTCTCCAAGCGCGAAGGGTTGGACCTGGAGGGGCAGATTTTCTCAGACACACAACCACTGC
ACCGGCTGGTGGCGGCGATGCTGGCTGCCGGCGAGGTTCACGCGCTGCGCGATCCCACGCGCGGAGGACTCGGGACCTCG
CTGTGCGAGATCGCGGATGCGTCGCGCGTGGGGGTAGAGATCGAAGCGCGGAGCCTCGCGGTGCGCGAAGAAGTGAAGGG
CGCATGCGAGTTGTTGGGTATCGACCCGCTGTTTGTGGCGAACGAGGGCAAACTGGTGGCGTTCGTCCACCCGGATACGG
CGGACGCCGTATTGAAGGCGATGCGCGCCACGCGCGAAGGACGTGAGGCGGCTATCATCGGACGCGCGGTGGAAGCGCAT
CCCGGAATGGTGGTGATGAAGACAGAAATCGGCGGCACACGGGTGCTGGACTTACCGTTCAACGAGCAATTGCCGCGCAT
CTGTTAG

Upstream 100 bases:

>100_bases
TCAGGAAGTGCATACGACGCTGCTGCACGTATTGTGGGATATGGTGCACGTGATGCTTGGCGAAGAAGACATAATCTGAG
ATCGTGACGGCGGAGGGGCT

Downstream 100 bases:

>100_bases
TGGCGGGTTATATATGGCACGTTGATTTGTTGACGCCTTCCATATACACGGGCACACTGAAGAAAGTCACGAAGAAGGAG
GGGCAAATGGCGGCAGACAC

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MAQSFVMTCPVPLTRHKTIVMGHGSGGRLTAQLVRDLFLPAFDNPLLRKLDDQAVVEAEGTRIAFTTDSFVVTPLFFPGG
NIGQLAVNGTVNDLAMSGAMPLGLSAAFILEEGLVIEELAAVAAAMGQAAAAAGVPIVTGDTKVVNRKSADKLFVTTTGI
GVVPRGVEISASNARPGDVVLLSGTIADHGMAVLSKREGLDLEGQIFSDTQPLHRLVAAMLAAGEVHALRDPTRGGLGTS
LCEIADASRVGVEIEARSLAVREEVKGACELLGIDPLFVANEGKLVAFVHPDTADAVLKAMRATREGREAAIIGRAVEAH
PGMVVMKTEIGGTRVLDLPFNEQLPRIC

Sequences:

>Translated_348_residues
MAQSFVMTCPVPLTRHKTIVMGHGSGGRLTAQLVRDLFLPAFDNPLLRKLDDQAVVEAEGTRIAFTTDSFVVTPLFFPGG
NIGQLAVNGTVNDLAMSGAMPLGLSAAFILEEGLVIEELAAVAAAMGQAAAAAGVPIVTGDTKVVNRKSADKLFVTTTGI
GVVPRGVEISASNARPGDVVLLSGTIADHGMAVLSKREGLDLEGQIFSDTQPLHRLVAAMLAAGEVHALRDPTRGGLGTS
LCEIADASRVGVEIEARSLAVREEVKGACELLGIDPLFVANEGKLVAFVHPDTADAVLKAMRATREGREAAIIGRAVEAH
PGMVVMKTEIGGTRVLDLPFNEQLPRIC
>Mature_347_residues
AQSFVMTCPVPLTRHKTIVMGHGSGGRLTAQLVRDLFLPAFDNPLLRKLDDQAVVEAEGTRIAFTTDSFVVTPLFFPGGN
IGQLAVNGTVNDLAMSGAMPLGLSAAFILEEGLVIEELAAVAAAMGQAAAAAGVPIVTGDTKVVNRKSADKLFVTTTGIG
VVPRGVEISASNARPGDVVLLSGTIADHGMAVLSKREGLDLEGQIFSDTQPLHRLVAAMLAAGEVHALRDPTRGGLGTSL
CEIADASRVGVEIEARSLAVREEVKGACELLGIDPLFVANEGKLVAFVHPDTADAVLKAMRATREGREAAIIGRAVEAHP
GMVVMKTEIGGTRVLDLPFNEQLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=337, Percent_Identity=48.3679525222552, Blast_Score=296, Evalue=2e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 36356; Mature: 36224

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQSFVMTCPVPLTRHKTIVMGHGSGGRLTAQLVRDLFLPAFDNPLLRKLDDQAVVEAEG
CCCCEEEECCCCCCCCEEEEEECCCCCEEHHHHHHHHHCCCCCCHHHHHCCCCEEEEECC
TRIAFTTDSFVVTPLFFPGGNIGQLAVNGTVNDLAMSGAMPLGLSAAFILEEGLVIEELA
CEEEEEECCEEEEEEECCCCCEEEEEECCCHHHHHHCCCCCCCCEEEEHHHCCCHHHHHH
AVAAAMGQAAAAAGVPIVTGDTKVVNRKSADKLFVTTTGIGVVPRGVEISASNARPGDVV
HHHHHHHHHHHHCCCEEEECCCCEECCCCCCEEEEEECCCCCCCCCEEEECCCCCCCCEE
LLSGTIADHGMAVLSKREGLDLEGQIFSDTQPLHRLVAAMLAAGEVHALRDPTRGGLGTS
EEECCCCCCCHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHCCCCEECCCCCCCCCCHH
LCEIADASRVGVEIEARSLAVREEVKGACELLGIDPLFVANEGKLVAFVHPDTADAVLKA
HHHHCCCCCCCEEEEHHHHHHHHHHHCHHEEECCCEEEEECCCCEEEEECCCCHHHHHHH
MRATREGREAAIIGRAVEAHPGMVVMKTEIGGTRVLDLPFNEQLPRIC
HHHHCCCCCEEEEEEEEECCCCEEEEEEECCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
AQSFVMTCPVPLTRHKTIVMGHGSGGRLTAQLVRDLFLPAFDNPLLRKLDDQAVVEAEG
CCCEEEECCCCCCCCEEEEEECCCCCEEHHHHHHHHHCCCCCCHHHHHCCCCEEEEECC
TRIAFTTDSFVVTPLFFPGGNIGQLAVNGTVNDLAMSGAMPLGLSAAFILEEGLVIEELA
CEEEEEECCEEEEEEECCCCCEEEEEECCCHHHHHHCCCCCCCCEEEEHHHCCCHHHHHH
AVAAAMGQAAAAAGVPIVTGDTKVVNRKSADKLFVTTTGIGVVPRGVEISASNARPGDVV
HHHHHHHHHHHHCCCEEEECCCCEECCCCCCEEEEEECCCCCCCCCEEEECCCCCCCCEE
LLSGTIADHGMAVLSKREGLDLEGQIFSDTQPLHRLVAAMLAAGEVHALRDPTRGGLGTS
EEECCCCCCCHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHCCCCEECCCCCCCCCCHH
LCEIADASRVGVEIEARSLAVREEVKGACELLGIDPLFVANEGKLVAFVHPDTADAVLKA
HHHHCCCCCCCEEEEHHHHHHHHHHHCHHEEECCCEEEEECCCCEEEEECCCCHHHHHHH
MRATREGREAAIIGRAVEAHPGMVVMKTEIGGTRVLDLPFNEQLPRIC
HHHHCCCCCEEEEEEEEECCCCEEEEEEECCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8326860 [H]