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The map label for this gene is gmhA [H]

Identifier: 116625604

GI number: 116625604

Start: 8215827

End: 8216432

Strand: Direct

Name: gmhA [H]

Synonym: Acid_6553

Alternate gene names: 116625604

Gene position: 8215827-8216432 (Clockwise)

Preceding gene: 116625603

Following gene: 116625605

Centisome position: 82.44

GC content: 62.38

Gene sequence:

>606_bases
GTGGCGGCACCGGCGTCGAAGGCTTTCCAGGAGGCGGTGTTGCGCAAATGCCGGGAGAGCGCCGAGACGAAGGAGAAATT
TTTCGCGGCGAATTCCGGCGTGCTCGAAGAGGTGTGCGGGCGGGTTGCCACGGCGCTCTCCGCCGGACATCAGTTGTTTG
TGATGGGCAACGGGGGAAGTTCCTGCGACGCGCTGCATGTGGCGGTGGAGTTCGTGCATCCGATCATCGAGAAGCGGCGG
GCGTTCCCGGCGCGGGCGCTGACCAGCGATACGGCGCTGTTGACGGCGATCGGCAACGACGCCGATTTCTCGCAGACCTT
CGCCGAGCAATTGCGGGTGTTCGGGAAGGCTGGAGACGTGGCGCTGGGGATATCGACCAGCGGGATGTCCGCGAACGTCA
ATTACGGACTGCAGGCGGCGCGCGAGATGGGGATGCTGACAGTCGCGTTCTCGGGCAAGGACGGCGGGCGATCGAAGGAT
GCGGCGGAGTATTGCCTGACGGTGCCAAGTTTCAGCATTCACCGGATTCAGGAAGTGCATACGACGCTGCTGCACGTATT
GTGGGATATGGTGCACGTGATGCTTGGCGAAGAAGACATAATCTGA

Upstream 100 bases:

>100_bases
GCAGACGCCGCTGGGAGCGACGATGGTGTCGGCGGAGGGCGCGTGCGCGGCGTACTACAACTACGGGCGGCATCTGGTAT
CGATCGCAGCGGAGGCGTGA

Downstream 100 bases:

>100_bases
GATCGTGACGGCGGAGGGGCTGTGGCGCAGAGCTTTGTGATGACGTGTCCGGTGCCGTTGACGCGGCATAAGACGATCGT
GATGGGCCATGGGAGTGGGG

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MAAPASKAFQEAVLRKCRESAETKEKFFAANSGVLEEVCGRVATALSAGHQLFVMGNGGSSCDALHVAVEFVHPIIEKRR
AFPARALTSDTALLTAIGNDADFSQTFAEQLRVFGKAGDVALGISTSGMSANVNYGLQAAREMGMLTVAFSGKDGGRSKD
AAEYCLTVPSFSIHRIQEVHTTLLHVLWDMVHVMLGEEDII

Sequences:

>Translated_201_residues
MAAPASKAFQEAVLRKCRESAETKEKFFAANSGVLEEVCGRVATALSAGHQLFVMGNGGSSCDALHVAVEFVHPIIEKRR
AFPARALTSDTALLTAIGNDADFSQTFAEQLRVFGKAGDVALGISTSGMSANVNYGLQAAREMGMLTVAFSGKDGGRSKD
AAEYCLTVPSFSIHRIQEVHTTLLHVLWDMVHVMLGEEDII
>Mature_200_residues
AAPASKAFQEAVLRKCRESAETKEKFFAANSGVLEEVCGRVATALSAGHQLFVMGNGGSSCDALHVAVEFVHPIIEKRRA
FPARALTSDTALLTAIGNDADFSQTFAEQLRVFGKAGDVALGISTSGMSANVNYGLQAAREMGMLTVAFSGKDGGRSKDA
AEYCLTVPSFSIHRIQEVHTTLLHVLWDMVHVMLGEEDII

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=186, Percent_Identity=38.1720430107527, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789539, Length=150, Percent_Identity=35.3333333333333, Blast_Score=94, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 21492; Mature: 21361

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPASKAFQEAVLRKCRESAETKEKFFAANSGVLEEVCGRVATALSAGHQLFVMGNGGS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCC
SCDALHVAVEFVHPIIEKRRAFPARALTSDTALLTAIGNDADFSQTFAEQLRVFGKAGDV
CHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCE
ALGISTSGMSANVNYGLQAAREMGMLTVAFSGKDGGRSKDAAEYCLTVPSFSIHRIQEVH
EEEEECCCCCCCCCHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHHHH
TTLLHVLWDMVHVMLGEEDII
HHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AAPASKAFQEAVLRKCRESAETKEKFFAANSGVLEEVCGRVATALSAGHQLFVMGNGGS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCC
SCDALHVAVEFVHPIIEKRRAFPARALTSDTALLTAIGNDADFSQTFAEQLRVFGKAGDV
CHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCE
ALGISTSGMSANVNYGLQAAREMGMLTVAFSGKDGGRSKDAAEYCLTVPSFSIHRIQEVH
EEEEECCCCCCCCCHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHHHH
TTLLHVLWDMVHVMLGEEDII
HHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]