Click here to switch to the map view.

The map label for this gene is degU [H]

Identifier: 116625514

GI number: 116625514

Start: 8096869

End: 8097444

Strand: Reverse

Name: degU [H]

Synonym: Acid_6461

Alternate gene names: 116625514

Gene position: 8097444-8096869 (Counterclockwise)

Preceding gene: 116625515

Following gene: 116625500

Centisome position: 81.25

GC content: 64.06

Gene sequence:

>576_bases
ATGATTCTCGGTGCGCAGGCCGACATGGAAATCGTCGGCGAGGCCGCCAACGGCCGCGAAGCCGTCGAGCTCGCTGAACA
ACTGCGTCCCGACGTCGTCGTAATGGACGTCGCCATGCCCGAGCTCAACGGCATCGAGGCCACGCGGCGCCTCGTCGCGG
CCAACGCGCACGCCAAGGTGATCGCCCTCAGCATGCACAAGGATTCCGTCTACGTGCGCGAAATCCTCCGCGCCGGCGCG
CGCGGCTACCTGCTCAAGGATTCCGGCGCCGGTGAGCTGGTCACCGCCATACGCGCCGTCGCCGGCGGCGAAAGCTATCT
AACACCCGCAGTCTCCAACGCCGTGCTCGACGACTACCGGAAGCACGTCACCAATCCCATCGATCTGCTCAGCAGCCGCG
AACGCGAGGTCCTGCAAATGCTCGCCGAAGGCAAGACCAACAAGGAGATCGCTGTCGTTCTCAACCTCAGCGTCTACACC
GTGGATGCCCACCGCGGCCGCATCATGGAGAAGTTGAACCTTCACAGCATCAACGAACTCGTCCGCTTCGCCGTCCGCAA
CGGCCTGGTGGATTGA

Upstream 100 bases:

>100_bases
GGCGAGGGTGTTTTAATTGAAGTGCGAGTACCGCTGAAACATGAAGAAAACCCGCATCCTGCTGTGTGACGATCACGCCG
TAGTCCGCCAGGGCTTCAAG

Downstream 100 bases:

>100_bases
GGCTGCGTCATCTAATCAATCACGTTTTTCGACTGCGTTCTTAGCCTGCCGCCAAACCCCCGCAAGCACCGCATAGTACT
CGGCGAGATCAACCGTCGTA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: Protease production enhancer protein [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MILGAQADMEIVGEAANGREAVELAEQLRPDVVVMDVAMPELNGIEATRRLVAANAHAKVIALSMHKDSVYVREILRAGA
RGYLLKDSGAGELVTAIRAVAGGESYLTPAVSNAVLDDYRKHVTNPIDLLSSREREVLQMLAEGKTNKEIAVVLNLSVYT
VDAHRGRIMEKLNLHSINELVRFAVRNGLVD

Sequences:

>Translated_191_residues
MILGAQADMEIVGEAANGREAVELAEQLRPDVVVMDVAMPELNGIEATRRLVAANAHAKVIALSMHKDSVYVREILRAGA
RGYLLKDSGAGELVTAIRAVAGGESYLTPAVSNAVLDDYRKHVTNPIDLLSSREREVLQMLAEGKTNKEIAVVLNLSVYT
VDAHRGRIMEKLNLHSINELVRFAVRNGLVD
>Mature_191_residues
MILGAQADMEIVGEAANGREAVELAEQLRPDVVVMDVAMPELNGIEATRRLVAANAHAKVIALSMHKDSVYVREILRAGA
RGYLLKDSGAGELVTAIRAVAGGESYLTPAVSNAVLDDYRKHVTNPIDLLSSREREVLQMLAEGKTNKEIAVVLNLSVYT
VDAHRGRIMEKLNLHSINELVRFAVRNGLVD

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=185, Percent_Identity=36.2162162162162, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790102, Length=181, Percent_Identity=38.121546961326, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788712, Length=185, Percent_Identity=32.972972972973, Blast_Score=102, Evalue=1e-23,
Organism=Escherichia coli, GI1788521, Length=168, Percent_Identity=36.9047619047619, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786747, Length=184, Percent_Identity=28.2608695652174, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787473, Length=160, Percent_Identity=35.625, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20766; Mature: 20766

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILGAQADMEIVGEAANGREAVELAEQLRPDVVVMDVAMPELNGIEATRRLVAANAHAKV
CEECCCCCHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEE
IALSMHKDSVYVREILRAGARGYLLKDSGAGELVTAIRAVAGGESYLTPAVSNAVLDDYR
EEEEECCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KHVTNPIDLLSSREREVLQMLAEGKTNKEIAVVLNLSVYTVDAHRGRIMEKLNLHSINEL
HHCCCHHHHHCCCHHHHHHHHHCCCCCCEEEEEEEEEEEEEECHHHHHHHHHHHHHHHHH
VRFAVRNGLVD
HHHHHHHCCCC
>Mature Secondary Structure
MILGAQADMEIVGEAANGREAVELAEQLRPDVVVMDVAMPELNGIEATRRLVAANAHAKV
CEECCCCCHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEE
IALSMHKDSVYVREILRAGARGYLLKDSGAGELVTAIRAVAGGESYLTPAVSNAVLDDYR
EEEEECCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KHVTNPIDLLSSREREVLQMLAEGKTNKEIAVVLNLSVYTVDAHRGRIMEKLNLHSINEL
HHCCCHHHHHCCCHHHHHHHHHCCCCCCEEEEEEEEEEEEEECHHHHHHHHHHHHHHHHH
VRFAVRNGLVD
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3136143; 3141378; 3141377; 9384377 [H]