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The map label for this gene is nreB [H]

Identifier: 116625515

GI number: 116625515

Start: 8097476

End: 8098825

Strand: Reverse

Name: nreB [H]

Synonym: Acid_6462

Alternate gene names: 116625515

Gene position: 8098825-8097476 (Counterclockwise)

Preceding gene: 116625516

Following gene: 116625514

Centisome position: 81.27

GC content: 63.7

Gene sequence:

>1350_bases
ATGTCGGCGACAGCACATCCGCGCGATACTGTTATCGCGATGCTCCCCCGGCAAATTACGCACCAGAATATCTTCCGGGT
TCTGATTGCCGGTTTTAGCCTGGTCACGCTGCTGCTTGCCGCCGCCGCCATCGTCAGCCTCCGTAATATTCAATCCATCC
AGCAGAATGCCGACAGCCTGGTGCGGGAACAATCGCTCAGCAACCGCCTGATCGATGAGTTGCATAGCCAGCAGACCACG
CTCAGCGAAGTCTTTTCCGTGCTGGCGCGCGACCCGGATTCCGTGGACTACTACAAAATCATGAGCCAGCTCGATGAGGC
CGATCGCGACATCGCGCGCATCTCCGCGGAAGGCGCGCGCACCGCCGAGCACGATCTCTGGCAGCGGCTCAATCTCTCTT
CCCTCGATTTCTCTCGCGAGGCTCGCCGCATCCTCGCCGCGGAAGCGCCGGAGACCTTCTCTTCCATCGACCTCTTTCGC
TTTCACGGCGCCTTCGCCAGCGTCGTCGCCCGGTTGCTCGAAGCCGAATACCGCAAGCTTAGCGTCGCACAGGCGCAGAT
CGAGCACCGCACCTCTCACCTCAGCGAAATCTCGCTGGTCTTCGCCGCCGCCAGCGTCGTGCTCGCGCTGATCTTCGCCG
TGTTCACGGTGCGTCTGGTTTCGCAGCTCATTCGTCAGATGGAATCCCAGACCGCTGAACTCGGCCGCGTCTCCTGGCAC
ATGCTGGAAGATCAGGAGGCCACCGCGCGCCGCTTCTCCCACGAGCTTCACGACGAGCTTGGTCAATCGCTCACCGCGGT
GAAGACCAATCTGACCGCGCTCGCGGGTACCACCGAGCCGCAGGCTCCGCGGCTCGCCGACTGCGTCCACCTGGTGGATG
AAGCCATCGGCAACGTGCGCCAGATGTCGCAGCTCCTGCGGCCCACCATCCTCGACGATTTCGGACTCGAGGCCGGCCTT
CGCTGGCTCGCCGACGGCTTCTCGGCGCGCACTGGCATAGAGGTCCACGTGGAATCCACGTACTCCGGCCGCCTTCCCGA
CGACACCGAGACGCACCTCTTTCGCATCTCCCAGGAAGCCCTCACCAACATCGCGCGCCACGCCGCCGCAAGGCACGTCA
CCGTCAAGCTGGATCGTAAGCCCGCCGAAATCTGTCTCTCCATCAGTGACGATGGCCGCGGCATCGCCGCCGCGCCGCAG
AACGGCCGCGGCCTCGGCATGATCGGCATGCGCGCCCGCGCGCGCAGCGCAGGCGGCGACGTCAACGTGCGTTCGCGGCC
CGGCGAGGGTGTTTTAATTGAAGTGCGAGTACCGCTGAAACATGAAGAAAACCCGCATCCTGCTGTGTGA

Upstream 100 bases:

>100_bases
GCGGCGAAAACTCGATAGCCTACACAGGCTAGACACAGCCCCGAATTCGCGGGTGTGCCGGTTAATGTTCTTTAGTCTGG
CGTCTTAGCCTACATTGGGG

Downstream 100 bases:

>100_bases
CGATCACGCCGTAGTCCGCCAGGGCTTCAAGATGATTCTCGGTGCGCAGGCCGACATGGAAATCGTCGGCGAGGCCGCCA
ACGGCCGCGAAGCCGTCGAG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSATAHPRDTVIAMLPRQITHQNIFRVLIAGFSLVTLLLAAAAIVSLRNIQSIQQNADSLVREQSLSNRLIDELHSQQTT
LSEVFSVLARDPDSVDYYKIMSQLDEADRDIARISAEGARTAEHDLWQRLNLSSLDFSREARRILAAEAPETFSSIDLFR
FHGAFASVVARLLEAEYRKLSVAQAQIEHRTSHLSEISLVFAAASVVLALIFAVFTVRLVSQLIRQMESQTAELGRVSWH
MLEDQEATARRFSHELHDELGQSLTAVKTNLTALAGTTEPQAPRLADCVHLVDEAIGNVRQMSQLLRPTILDDFGLEAGL
RWLADGFSARTGIEVHVESTYSGRLPDDTETHLFRISQEALTNIARHAAARHVTVKLDRKPAEICLSISDDGRGIAAAPQ
NGRGLGMIGMRARARSAGGDVNVRSRPGEGVLIEVRVPLKHEENPHPAV

Sequences:

>Translated_449_residues
MSATAHPRDTVIAMLPRQITHQNIFRVLIAGFSLVTLLLAAAAIVSLRNIQSIQQNADSLVREQSLSNRLIDELHSQQTT
LSEVFSVLARDPDSVDYYKIMSQLDEADRDIARISAEGARTAEHDLWQRLNLSSLDFSREARRILAAEAPETFSSIDLFR
FHGAFASVVARLLEAEYRKLSVAQAQIEHRTSHLSEISLVFAAASVVLALIFAVFTVRLVSQLIRQMESQTAELGRVSWH
MLEDQEATARRFSHELHDELGQSLTAVKTNLTALAGTTEPQAPRLADCVHLVDEAIGNVRQMSQLLRPTILDDFGLEAGL
RWLADGFSARTGIEVHVESTYSGRLPDDTETHLFRISQEALTNIARHAAARHVTVKLDRKPAEICLSISDDGRGIAAAPQ
NGRGLGMIGMRARARSAGGDVNVRSRPGEGVLIEVRVPLKHEENPHPAV
>Mature_448_residues
SATAHPRDTVIAMLPRQITHQNIFRVLIAGFSLVTLLLAAAAIVSLRNIQSIQQNADSLVREQSLSNRLIDELHSQQTTL
SEVFSVLARDPDSVDYYKIMSQLDEADRDIARISAEGARTAEHDLWQRLNLSSLDFSREARRILAAEAPETFSSIDLFRF
HGAFASVVARLLEAEYRKLSVAQAQIEHRTSHLSEISLVFAAASVVLALIFAVFTVRLVSQLIRQMESQTAELGRVSWHM
LEDQEATARRFSHELHDELGQSLTAVKTNLTALAGTTEPQAPRLADCVHLVDEAIGNVRQMSQLLRPTILDDFGLEAGLR
WLADGFSARTGIEVHVESTYSGRLPDDTETHLFRISQEALTNIARHAAARHVTVKLDRKPAEICLSISDDGRGIAAAPQN
GRGLGMIGMRARARSAGGDVNVRSRPGEGVLIEVRVPLKHEENPHPAV

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=189, Percent_Identity=29.6296296296296, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI87082311, Length=222, Percent_Identity=30.6306306306306, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49523; Mature: 49392

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATAHPRDTVIAMLPRQITHQNIFRVLIAGFSLVTLLLAAAAIVSLRNIQSIQQNADSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VREQSLSNRLIDELHSQQTTLSEVFSVLARDPDSVDYYKIMSQLDEADRDIARISAEGAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
TAEHDLWQRLNLSSLDFSREARRILAAEAPETFSSIDLFRFHGAFASVVARLLEAEYRKL
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAQAQIEHRTSHLSEISLVFAAASVVLALIFAVFTVRLVSQLIRQMESQTAELGRVSWH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLEDQEATARRFSHELHDELGQSLTAVKTNLTALAGTTEPQAPRLADCVHLVDEAIGNVR
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHH
QMSQLLRPTILDDFGLEAGLRWLADGFSARTGIEVHVESTYSGRLPDDTETHLFRISQEA
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHH
LTNIARHAAARHVTVKLDRKPAEICLSISDDGRGIAAAPQNGRGLGMIGMRARARSAGGD
HHHHHHHHHHCEEEEEECCCCHHEEEEECCCCCEEEECCCCCCCCCEECHHHHHHCCCCC
VNVRSRPGEGVLIEVRVPLKHEENPHPAV
CEECCCCCCCEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SATAHPRDTVIAMLPRQITHQNIFRVLIAGFSLVTLLLAAAAIVSLRNIQSIQQNADSL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VREQSLSNRLIDELHSQQTTLSEVFSVLARDPDSVDYYKIMSQLDEADRDIARISAEGAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
TAEHDLWQRLNLSSLDFSREARRILAAEAPETFSSIDLFRFHGAFASVVARLLEAEYRKL
HHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAQAQIEHRTSHLSEISLVFAAASVVLALIFAVFTVRLVSQLIRQMESQTAELGRVSWH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLEDQEATARRFSHELHDELGQSLTAVKTNLTALAGTTEPQAPRLADCVHLVDEAIGNVR
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHH
QMSQLLRPTILDDFGLEAGLRWLADGFSARTGIEVHVESTYSGRLPDDTETHLFRISQEA
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHH
LTNIARHAAARHVTVKLDRKPAEICLSISDDGRGIAAAPQNGRGLGMIGMRARARSAGGD
HHHHHHHHHHCEEEEEECCCCHHEEEEECCCCCEEEECCCCCCCCCEECHHHHHHCCCCC
VNVRSRPGEGVLIEVRVPLKHEENPHPAV
CEECCCCCCCEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA