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The map label for this gene is tadA [H]

Identifier: 116625482

GI number: 116625482

Start: 8048955

End: 8049383

Strand: Reverse

Name: tadA [H]

Synonym: Acid_6428

Alternate gene names: 116625482

Gene position: 8049383-8048955 (Counterclockwise)

Preceding gene: 116625484

Following gene: 116625480

Centisome position: 80.77

GC content: 67.13

Gene sequence:

>429_bases
ATGTACCAGGCTCTCGCCCTGGCGCGCAGCGGCGCCGCTCTGGGCGAGGTTCCGGTGGGCGCTGTGATCGCCCTCGCCGG
CGAAGTGATCGGCCGCGGCAGCAATGCCCCGGTGGCGCAGATGGACCCCACCGCGCACGCCGAGATCCTGGCCATCCGCG
AGGCCGCCTCGCGGATTGCCAACTACCGCCTAACCGGCGCCACACTGTACTGCACTCTCGAGCCCTGCGTGATGTGTGCC
GGAGCCCTGGTTGCGGCACGCATCGAACGCGTCGTCTTCGGAGCTCGCGACCTGCGCTTCGGCGGCGTGCGCAGCAAATT
CCAACTCGCCGATTCCGACCTACTCAATCACCGTGTCGAAATCGTAGAGGGCGTCCTCGCGGTCGAGTGCGTCCAACTCC
TCCGCGAATTCTTCGAAAACCGCCGCTAG

Upstream 100 bases:

>100_bases
CAGCGGGTCCTTCTCGTGTTCGGTTTCGTGGTGAATTTCAAGTTCGGCCATAGCGGATTTCCGTATTATAGAGGCTTCCG
TGACTACAGACGAACAATTC

Downstream 100 bases:

>100_bases
TACGGCCGGGTGCTGCGCCTGTCCTAAACAAGAGCTAACTGCTCTTCAGTAGGCTCCGCTCAACAATACCAGGGCTCCGT
CAAATACGGGATCGTCGCGC

Product: tRNA-adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MYQALALARSGAALGEVPVGAVIALAGEVIGRGSNAPVAQMDPTAHAEILAIREAASRIANYRLTGATLYCTLEPCVMCA
GALVAARIERVVFGARDLRFGGVRSKFQLADSDLLNHRVEIVEGVLAVECVQLLREFFENRR

Sequences:

>Translated_142_residues
MYQALALARSGAALGEVPVGAVIALAGEVIGRGSNAPVAQMDPTAHAEILAIREAASRIANYRLTGATLYCTLEPCVMCA
GALVAARIERVVFGARDLRFGGVRSKFQLADSDLLNHRVEIVEGVLAVECVQLLREFFENRR
>Mature_142_residues
MYQALALARSGAALGEVPVGAVIALAGEVIGRGSNAPVAQMDPTAHAEILAIREAASRIANYRLTGATLYCTLEPCVMCA
GALVAARIERVVFGARDLRFGGVRSKFQLADSDLLNHRVEIVEGVLAVECVQLLREFFENRR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=147, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI145693172, Length=142, Percent_Identity=54.2253521126761, Blast_Score=152, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17541138, Length=146, Percent_Identity=37.6712328767123, Blast_Score=96, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17554608, Length=96, Percent_Identity=41.6666666666667, Blast_Score=83, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17555996, Length=97, Percent_Identity=37.1134020618557, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322425, Length=163, Percent_Identity=30.6748466257669, Blast_Score=66, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=33.7931034482759, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15197; Mature: 15197

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQALALARSGAALGEVPVGAVIALAGEVIGRGSNAPVAQMDPTAHAEILAIREAASRIA
CCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
NYRLTGATLYCTLEPCVMCAGALVAARIERVVFGARDLRFGGVRSKFQLADSDLLNHRVE
CCEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
IVEGVLAVECVQLLREFFENRR
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYQALALARSGAALGEVPVGAVIALAGEVIGRGSNAPVAQMDPTAHAEILAIREAASRIA
CCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
NYRLTGATLYCTLEPCVMCAGALVAARIERVVFGARDLRFGGVRSKFQLADSDLLNHRVE
CCEECCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
IVEGVLAVECVQLLREFFENRR
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]