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The map label for this gene is degS [H]

Identifier: 116625454

GI number: 116625454

Start: 8018220

End: 8019317

Strand: Direct

Name: degS [H]

Synonym: Acid_6399

Alternate gene names: 116625454

Gene position: 8018220-8019317 (Clockwise)

Preceding gene: 116625453

Following gene: 116625455

Centisome position: 80.46

GC content: 68.4

Gene sequence:

>1098_bases
ATGCCTGGCCTTGTGGGGCAGGCAATCCTGCCTGCAGCCGCCTTTCAGGCGGCTTCTTCGCCGTGCGCGACACCCCGCCC
GACACCCCGCCCATTTCCAGCCTGGGGCTGTGGGAGAGCCGCCGCCGCGGTACACGCACCCCCCGCTCTCCCGGCCTGCC
CGATCTACCGGTGTGCCCAAACTCCCTCCGGAGCGATCCTGGAATCACAGGAGATGAACATGGCAAACGAACTGGCCGCC
CTTTCGAATGAAATCGCGGCGGCTGTGGAGGTAGCGGGGAAGAACGTGGTCGCGGTGCATGCGCGCCCCAGGTTTTCCTC
GAGCGGAGTATTCTGGCGACCGGGTGTGATCGTCACGGCGGAGCACACTATCCAGCGCGAAGAAGAGATCACCGTGACCC
TCCCCGATGGCCGGAACGCCCCGGCGACCCTCGCCGGCTCGGACGCAGGCACCGACCTCGCGGTCCTCAAAATCGAAGGC
GCCGCGTTCGCGCCCGGCCACACTACCGCCGCGCCCGCGGCCGGAACCCTGGCGCTCGCCATCGGACGCTCGGAGGATTC
CGGCGTGAACGCCACGCTCGGCATCATCAGCGCCTGCAGCGGCGAATGGCGCACCTGGCGCGGCGGACGCCTCGATCATT
ACATCCGGCTCGACCTCACGCTCTACCCGGGGTCGGACGGAGGCGCCGTGGTCAACACGGCGGGCGAGACCATTGGTATC
GCGACCAGCGCCCTCTCGCGCATAGCAGGACTGGCGATACCGGCGGTCACCGTGGACCGCGTCGTCGATGAGATTCTGGC
GCGCGGACGCGTAGCGCGCGGCTATCTCGGCGTCGGTTTGCAACCGGTGGAACTCCCGGATCATCAGAAAGGCCTGATCG
TGCTTTCGCTCGAGCCGGCCGGACCGGCCGCGGCCGCCGGCGTGCTGATCGGCGACATCCTGGTGAAGCTCGGGGGCAAA
GCGGTGCACGACACGGAGGATATCCAACTCGGCTTGGAAGGCCACGCGGTCGGGCTAAAGGTGGAGGTGGAGGTGCTGCG
CGGCGGCGAAGCGCGGCAGGTGAACGTGGTGGTCGGCGAACGGCCGCGGAGGAACTGA

Upstream 100 bases:

>100_bases
GAGCACCGACCGCAAGGGAGCGATCGTCTGATCGTGGTTTGCGGCCTGCCGCAATGTACTACTATGCATTTGCTTGCTCG
TAGGCCGCGACGATTCCAGG

Downstream 100 bases:

>100_bases
GATGCGGGGATTCGGAGAAATCGCGGAGCGCCTCAGGCGCTCCACCGTGCAGGTGCGCCTAAACAAACACGGCGGCGGCA
GCGGCATCGTCTGGAAGCCC

Product: PDZ/DHR/GLGF domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MPGLVGQAILPAAAFQAASSPCATPRPTPRPFPAWGCGRAAAAVHAPPALPACPIYRCAQTPSGAILESQEMNMANELAA
LSNEIAAAVEVAGKNVVAVHARPRFSSSGVFWRPGVIVTAEHTIQREEEITVTLPDGRNAPATLAGSDAGTDLAVLKIEG
AAFAPGHTTAAPAAGTLALAIGRSEDSGVNATLGIISACSGEWRTWRGGRLDHYIRLDLTLYPGSDGGAVVNTAGETIGI
ATSALSRIAGLAIPAVTVDRVVDEILARGRVARGYLGVGLQPVELPDHQKGLIVLSLEPAGPAAAAGVLIGDILVKLGGK
AVHDTEDIQLGLEGHAVGLKVEVEVLRGGEARQVNVVVGERPRRN

Sequences:

>Translated_365_residues
MPGLVGQAILPAAAFQAASSPCATPRPTPRPFPAWGCGRAAAAVHAPPALPACPIYRCAQTPSGAILESQEMNMANELAA
LSNEIAAAVEVAGKNVVAVHARPRFSSSGVFWRPGVIVTAEHTIQREEEITVTLPDGRNAPATLAGSDAGTDLAVLKIEG
AAFAPGHTTAAPAAGTLALAIGRSEDSGVNATLGIISACSGEWRTWRGGRLDHYIRLDLTLYPGSDGGAVVNTAGETIGI
ATSALSRIAGLAIPAVTVDRVVDEILARGRVARGYLGVGLQPVELPDHQKGLIVLSLEPAGPAAAAGVLIGDILVKLGGK
AVHDTEDIQLGLEGHAVGLKVEVEVLRGGEARQVNVVVGERPRRN
>Mature_364_residues
PGLVGQAILPAAAFQAASSPCATPRPTPRPFPAWGCGRAAAAVHAPPALPACPIYRCAQTPSGAILESQEMNMANELAAL
SNEIAAAVEVAGKNVVAVHARPRFSSSGVFWRPGVIVTAEHTIQREEEITVTLPDGRNAPATLAGSDAGTDLAVLKIEGA
AFAPGHTTAAPAAGTLALAIGRSEDSGVNATLGIISACSGEWRTWRGGRLDHYIRLDLTLYPGSDGGAVVNTAGETIGIA
TSALSRIAGLAIPAVTVDRVVDEILARGRVARGYLGVGLQPVELPDHQKGLIVLSLEPAGPAAAAGVLIGDILVKLGGKA
VHDTEDIQLGLEGHAVGLKVEVEVLRGGEARQVNVVVGERPRRN

Specific function: Unknown

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI24308541, Length=310, Percent_Identity=26.1290322580645, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI22129776, Length=285, Percent_Identity=26.3157894736842, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4506141, Length=312, Percent_Identity=25.3205128205128, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1789630, Length=282, Percent_Identity=33.6879432624113, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1789629, Length=265, Percent_Identity=30.9433962264151, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1786356, Length=263, Percent_Identity=32.319391634981, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011783
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 37362; Mature: 37231

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGLVGQAILPAAAFQAASSPCATPRPTPRPFPAWGCGRAAAAVHAPPALPACPIYRCAQ
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHCC
TPSGAILESQEMNMANELAALSNEIAAAVEVAGKNVVAVHARPRFSSSGVFWRPGVIVTA
CCCCCEEECHHCCHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCEEECCCEEEEE
EHTIQREEEITVTLPDGRNAPATLAGSDAGTDLAVLKIEGAAFAPGHTTAAPAAGTLALA
HHHCCCCCEEEEECCCCCCCCCEEECCCCCCCEEEEEECCCEECCCCCCCCCCCCEEEEE
IGRSEDSGVNATLGIISACSGEWRTWRGGRLDHYIRLDLTLYPGSDGGAVVNTAGETIGI
EECCCCCCCEEEEEEEECCCCCCEECCCCCCCEEEEEEEEEEECCCCCEEEECCCCEEHH
ATSALSRIAGLAIPAVTVDRVVDEILARGRVARGYLGVGLQPVELPDHQKGLIVLSLEPA
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEECCCCCCCCEECCCCCCCCCEEEEEECCC
GPAAAAGVLIGDILVKLGGKAVHDTEDIQLGLEGHAVGLKVEVEVLRGGEARQVNVVVGE
CCHHHHHHHHHHHHHHHCCCEECCCCCEEEEECCEEEEEEEEEEEECCCCCEEEEEEECC
RPRRN
CCCCC
>Mature Secondary Structure 
PGLVGQAILPAAAFQAASSPCATPRPTPRPFPAWGCGRAAAAVHAPPALPACPIYRCAQ
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHCC
TPSGAILESQEMNMANELAALSNEIAAAVEVAGKNVVAVHARPRFSSSGVFWRPGVIVTA
CCCCCEEECHHCCHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCEEECCCEEEEE
EHTIQREEEITVTLPDGRNAPATLAGSDAGTDLAVLKIEGAAFAPGHTTAAPAAGTLALA
HHHCCCCCEEEEECCCCCCCCCEEECCCCCCCEEEEEECCCEECCCCCCCCCCCCEEEEE
IGRSEDSGVNATLGIISACSGEWRTWRGGRLDHYIRLDLTLYPGSDGGAVVNTAGETIGI
EECCCCCCCEEEEEEEECCCCCCEECCCCCCCEEEEEEEEEEECCCCCEEEECCCCEEHH
ATSALSRIAGLAIPAVTVDRVVDEILARGRVARGYLGVGLQPVELPDHQKGLIVLSLEPA
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEECCCCCCCCEECCCCCCCCCEEEEEECCC
GPAAAAGVLIGDILVKLGGKAVHDTEDIQLGLEGHAVGLKVEVEVLRGGEARQVNVVVGE
CCHHHHHHHHHHHHHHHCCCEECCCCCEEEEECCEEEEEEEEEEEECCCCCEEEEEEECC
RPRRN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]