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The map label for this gene is 116625435

Identifier: 116625435

GI number: 116625435

Start: 7997063

End: 7997908

Strand: Reverse

Name: 116625435

Synonym: Acid_6380

Alternate gene names: NA

Gene position: 7997908-7997063 (Counterclockwise)

Preceding gene: 116625440

Following gene: 116625434

Centisome position: 80.25

GC content: 66.08

Gene sequence:

>846_bases
ATGAAGCAGCAGTGGGACGACTTGCGAGCACTCTTCGATGCGGCATGGCCGCTGCCCGCGGCGGCGCGCTCGGAGTTTCT
GAACGAGCGCTGCGGGGACGACCCACGCTTCCGCCGCGAACTGGAAAAGCTGCTGGCGGCGCACGACGAAGGCGAAGCGG
CGGCGGCACGGAACGCTGCCGGACGCCGGCGATTCGGCGCATGGGAGACGATCGGGCGCGCCGGGCAGGACGACGGGAAT
GTCTACCTGGTGGAGCGCATGGACGGGCAGCCTCCCCAGCGCGCGTCGCTCAAGGTGATGGCGCGCAGAATGGTCTCGTC
CGAGTATCTGGACCGGTTCCGGCGCGAGCGTGAAATCCTGGCGCGGCTGGATCATTCGCACATCGCACGCCTGGTCGATG
GCGGGGTGAGTGAATCGGGCGAGGCCTACCTGGTAGCGGAGTATGTGGAAGGGGCGCCGGTGGACGAATACTGCGAACAG
TGCGGCCTGCCGCTCCAAGCACGGCTGCGGCTGTTCCTCGCGCTCTGCTCGGCGGTGGAATGCGCGCATTGCAACCTGAT
TGTGCATCGCGATATCCGTCCGGCGAACGTCCTGGTGACGCGCGAGGGAGTGTTGAAGCTGGTGAATTTCGGGAATGGGG
ATCCGACGGAGAACGTGACCACTGCGGTGGATGTCCGGGGCTTGGGTGTCACGCTGGGCCGGCTCGTTCCGAAGCATGGG
GGCTGCCTGGCCGGCGTCATCCTCAAGGCGGCCGAGAGCGATCCCGCGCAGCAATACGGGTCGGCCTTCCAATTGGCTCG
TGACGTTGAGCAGTACCTGGAAAAGCTTTTCGTGCAGGCGCGTTGA

Upstream 100 bases:

>100_bases
GAAATCCGAGGAGGAGGGTAAGGGAAAATACCCTGACAATCTTTTTGCCGGCGGTCTATTCTTATGAAAGAATAGTCCGG
CATGCGGCCGTGAAGCAGCC

Downstream 100 bases:

>100_bases
AGGGCCGGAACGCACAATGGCAGGGGGCCTGCACCTGCTCAGGTATGAAATACCTGGTCACATTCCGAAAGCGTTTTGGA
GCGGACGGCGAGCCCGCCGA

Product: serine/threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKQQWDDLRALFDAAWPLPAAARSEFLNERCGDDPRFRRELEKLLAAHDEGEAAAARNAAGRRRFGAWETIGRAGQDDGN
VYLVERMDGQPPQRASLKVMARRMVSSEYLDRFRREREILARLDHSHIARLVDGGVSESGEAYLVAEYVEGAPVDEYCEQ
CGLPLQARLRLFLALCSAVECAHCNLIVHRDIRPANVLVTREGVLKLVNFGNGDPTENVTTAVDVRGLGVTLGRLVPKHG
GCLAGVILKAAESDPAQQYGSAFQLARDVEQYLEKLFVQAR

Sequences:

>Translated_281_residues
MKQQWDDLRALFDAAWPLPAAARSEFLNERCGDDPRFRRELEKLLAAHDEGEAAAARNAAGRRRFGAWETIGRAGQDDGN
VYLVERMDGQPPQRASLKVMARRMVSSEYLDRFRREREILARLDHSHIARLVDGGVSESGEAYLVAEYVEGAPVDEYCEQ
CGLPLQARLRLFLALCSAVECAHCNLIVHRDIRPANVLVTREGVLKLVNFGNGDPTENVTTAVDVRGLGVTLGRLVPKHG
GCLAGVILKAAESDPAQQYGSAFQLARDVEQYLEKLFVQAR
>Mature_281_residues
MKQQWDDLRALFDAAWPLPAAARSEFLNERCGDDPRFRRELEKLLAAHDEGEAAAARNAAGRRRFGAWETIGRAGQDDGN
VYLVERMDGQPPQRASLKVMARRMVSSEYLDRFRREREILARLDHSHIARLVDGGVSESGEAYLVAEYVEGAPVDEYCEQ
CGLPLQARLRLFLALCSAVECAHCNLIVHRDIRPANVLVTREGVLKLVNFGNGDPTENVTTAVDVRGLGVTLGRLVPKHG
GCLAGVILKAAESDPAQQYGSAFQLARDVEQYLEKLFVQAR

Specific function: Unknown

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI116089335, Length=122, Percent_Identity=31.9672131147541, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17136516, Length=144, Percent_Identity=34.0277777777778, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161077232, Length=119, Percent_Identity=33.6134453781513, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161077230, Length=119, Percent_Identity=33.6134453781513, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24655167, Length=119, Percent_Identity=33.6134453781513, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR005543
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271 [H]

Pfam domain/function: PF03793 PASTA; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 31185; Mature: 31185

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00109 PROTEIN_KINASE_TYR ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQQWDDLRALFDAAWPLPAAARSEFLNERCGDDPRFRRELEKLLAAHDEGEAAAARNAA
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
GRRRFGAWETIGRAGQDDGNVYLVERMDGQPPQRASLKVMARRMVSSEYLDRFRREREIL
HHHHCCHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARLDHSHIARLVDGGVSESGEAYLVAEYVEGAPVDEYCEQCGLPLQARLRLFLALCSAVE
HHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
CAHCNLIVHRDIRPANVLVTREGVLKLVNFGNGDPTENVTTAVDVRGLGVTLGRLVPKHG
HHHCCEEEECCCCCCEEEEEHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHCCCCC
GCLAGVILKAAESDPAQQYGSAFQLARDVEQYLEKLFVQAR
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKQQWDDLRALFDAAWPLPAAARSEFLNERCGDDPRFRRELEKLLAAHDEGEAAAARNAA
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
GRRRFGAWETIGRAGQDDGNVYLVERMDGQPPQRASLKVMARRMVSSEYLDRFRREREIL
HHHHCCHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARLDHSHIARLVDGGVSESGEAYLVAEYVEGAPVDEYCEQCGLPLQARLRLFLALCSAVE
HHHHHHHHHHHHHCCCCCCCCEEEEEEHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
CAHCNLIVHRDIRPANVLVTREGVLKLVNFGNGDPTENVTTAVDVRGLGVTLGRLVPKHG
HHHCCEEEECCCCCCEEEEEHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHCCCCC
GCLAGVILKAAESDPAQQYGSAFQLARDVEQYLEKLFVQAR
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]