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The map label for this gene is gcp

Identifier: 116625245

GI number: 116625245

Start: 7764973

End: 7766055

Strand: Reverse

Name: gcp

Synonym: Acid_6190

Alternate gene names: 116625245

Gene position: 7766055-7764973 (Counterclockwise)

Preceding gene: 116625246

Following gene: 116625243

Centisome position: 77.93

GC content: 66.3

Gene sequence:

>1083_bases
GTGCAGCGAATTTTGGGCATCGAATCTTCGTGCGACGAAACCGCCGCCGCCGTGGTGGAAGACGGTGAGCGTGTCCTTTC
GAGCGTGGTGGCGTCGCAGATGAGCACTCACGGCCGCTATGGAGGCGTGGTGCCGGAACTGGCGTCCCGCGAACATCTGC
GGGCGATTGTCCCCGTAGTGCGCGAGGCGCTCGAACGGTCGGCGACGCGCCTGGAGGATCTGGCGGCGATCGCAGTGACC
GTGGGACCGGGCCTGGTCGGGTCGCTTCTGGTGGGGCTGACGTATGCGAAAAGTTTGAGCCTGGCGAGCGGCGTGGGGCT
GATCGGCGTGAATCACATCGAGGGGCACATCCACGCCGTGATCCTCGAAGCGCGGCGCGACGGCACACCGGTCGAGTTCC
CGGCGCTGGCGTTGGTGGCGAGCGGCGGGCACACTCATTTGTTCGAAGTCCGCGAGGATTTCACGTACCGTCTGCTCGGC
AAGACGCGCGACGACGCGGCGGGCGAAGCCTTCGATAAGGTCGGCAAGCTGCTGGGCTTCGGATATCCGGGCGGCCCCGT
GATCGACCGCCTGGCGCCGCACGGGGATCCGCTGGCGGTCCGCTTCACCTTCGCGAAGATGAAGGGCAATGCGCTCGATT
TCAGCTTCAGCGGACTGAAGACCGCGGTGCTGCGCTGGGTCGAGGCGCACGATATGGAGGCCGAGATCGCCGCACGAAAG
GCGCTGGTCCGCGACAATCCGTCGCCGGACCTGGACCAGTGGCTGGCGGTCACGCCCAAACGCACTCTGGACCTTGCGGC
TTCGTTTCAGCACGCGGTAATTCACGAGCTGCTGACGCGTGCGGCGGCATCGGCCGAACGGATCGGTGCGCGCAGCCTGA
TCGTGTCGGGCGGAGTGGCGTGCAATTCGGGACTGCGCTCGGCCGCATACGCCAGCAGGCTGCCGTATGCCGTGCATTTC
CCCTCCTTCGGGCTCTCCACGGACAACGCGGCGATGATCGCAGCCGCGGCCTTCCCGAAACTGGCGCGCCGCGAATTCTC
CGGACTGGATATCGCAGCGCAGGCAAATCTCACCTTAGCCTGA

Upstream 100 bases:

>100_bases
GCCTGTTGAACTACAGCGCGCGGCGTGGGGCTCGCCCTGCTAACGTTCCCATGGAGCGGCTCGTGCTGGAGTCCGACGAA
CCCGCGCTAAGGTATTACTA

Downstream 100 bases:

>100_bases
GCCCCGACGCTCCGATAAGCTTCACTTACTTCCTATTCAGCGGCGCTCTTGCCACAAACTGGAGCGGCCAATATTTCCCG
AACTCTCGCTTTGAGGGTCT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MQRILGIESSCDETAAAVVEDGERVLSSVVASQMSTHGRYGGVVPELASREHLRAIVPVVREALERSATRLEDLAAIAVT
VGPGLVGSLLVGLTYAKSLSLASGVGLIGVNHIEGHIHAVILEARRDGTPVEFPALALVASGGHTHLFEVREDFTYRLLG
KTRDDAAGEAFDKVGKLLGFGYPGGPVIDRLAPHGDPLAVRFTFAKMKGNALDFSFSGLKTAVLRWVEAHDMEAEIAARK
ALVRDNPSPDLDQWLAVTPKRTLDLAASFQHAVIHELLTRAAASAERIGARSLIVSGGVACNSGLRSAAYASRLPYAVHF
PSFGLSTDNAAMIAAAAFPKLARREFSGLDIAAQANLTLA

Sequences:

>Translated_360_residues
MQRILGIESSCDETAAAVVEDGERVLSSVVASQMSTHGRYGGVVPELASREHLRAIVPVVREALERSATRLEDLAAIAVT
VGPGLVGSLLVGLTYAKSLSLASGVGLIGVNHIEGHIHAVILEARRDGTPVEFPALALVASGGHTHLFEVREDFTYRLLG
KTRDDAAGEAFDKVGKLLGFGYPGGPVIDRLAPHGDPLAVRFTFAKMKGNALDFSFSGLKTAVLRWVEAHDMEAEIAARK
ALVRDNPSPDLDQWLAVTPKRTLDLAASFQHAVIHELLTRAAASAERIGARSLIVSGGVACNSGLRSAAYASRLPYAVHF
PSFGLSTDNAAMIAAAAFPKLARREFSGLDIAAQANLTLA
>Mature_360_residues
MQRILGIESSCDETAAAVVEDGERVLSSVVASQMSTHGRYGGVVPELASREHLRAIVPVVREALERSATRLEDLAAIAVT
VGPGLVGSLLVGLTYAKSLSLASGVGLIGVNHIEGHIHAVILEARRDGTPVEFPALALVASGGHTHLFEVREDFTYRLLG
KTRDDAAGEAFDKVGKLLGFGYPGGPVIDRLAPHGDPLAVRFTFAKMKGNALDFSFSGLKTAVLRWVEAHDMEAEIAARK
ALVRDNPSPDLDQWLAVTPKRTLDLAASFQHAVIHELLTRAAASAERIGARSLIVSGGVACNSGLRSAAYASRLPYAVHF
PSFGLSTDNAAMIAAAAFPKLARREFSGLDIAAQANLTLA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=355, Percent_Identity=32.3943661971831, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI8923380, Length=342, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=9e-19,
Organism=Escherichia coli, GI1789445, Length=362, Percent_Identity=40.6077348066298, Blast_Score=237, Evalue=8e-64,
Organism=Caenorhabditis elegans, GI17557464, Length=359, Percent_Identity=27.5766016713092, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71995670, Length=344, Percent_Identity=28.7790697674419, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320099, Length=379, Percent_Identity=28.7598944591029, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6322891, Length=364, Percent_Identity=26.9230769230769, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI20129063, Length=384, Percent_Identity=31.7708333333333, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21357207, Length=304, Percent_Identity=29.2763157894737, Blast_Score=105, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_SOLUE (Q01TA4)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_827401.1
- STRING:   Q01TA4
- MEROPS:   M22.001
- GeneID:   4425596
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_6190
- NMPDR:   fig|234267.9.peg.5878
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   MEVIGQT
- ProtClustDB:   PRK09604
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 38057; Mature: 38057

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS01016 GLYCOPROTEASE; PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRILGIESSCDETAAAVVEDGERVLSSVVASQMSTHGRYGGVVPELASREHLRAIVPVV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
REALERSATRLEDLAAIAVTVGPGLVGSLLVGLTYAKSLSLASGVGLIGVNHIEGHIHAV
HHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEE
ILEARRDGTPVEFPALALVASGGHTHLFEVREDFTYRLLGKTRDDAAGEAFDKVGKLLGF
EEEECCCCCCCCCCCEEEEECCCCEEEEEHHHCHHHHHHCCCCCCHHHHHHHHHHHHHCC
GYPGGPVIDRLAPHGDPLAVRFTFAKMKGNALDFSFSGLKTAVLRWVEAHDMEAEIAARK
CCCCCHHHHHHCCCCCCEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHH
ALVRDNPSPDLDQWLAVTPKRTLDLAASFQHAVIHELLTRAAASAERIGARSLIVSGGVA
HHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEECCCH
CNSGLRSAAYASRLPYAVHFPSFGLSTDNAAMIAAAAFPKLARREFSGLDIAAQANLTLA
HCCCHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCEEC
>Mature Secondary Structure
MQRILGIESSCDETAAAVVEDGERVLSSVVASQMSTHGRYGGVVPELASREHLRAIVPVV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
REALERSATRLEDLAAIAVTVGPGLVGSLLVGLTYAKSLSLASGVGLIGVNHIEGHIHAV
HHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEE
ILEARRDGTPVEFPALALVASGGHTHLFEVREDFTYRLLGKTRDDAAGEAFDKVGKLLGF
EEEECCCCCCCCCCCEEEEECCCCEEEEEHHHCHHHHHHCCCCCCHHHHHHHHHHHHHCC
GYPGGPVIDRLAPHGDPLAVRFTFAKMKGNALDFSFSGLKTAVLRWVEAHDMEAEIAARK
CCCCCHHHHHHCCCCCCEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHHHH
ALVRDNPSPDLDQWLAVTPKRTLDLAASFQHAVIHELLTRAAASAERIGARSLIVSGGVA
HHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEECCCH
CNSGLRSAAYASRLPYAVHFPSFGLSTDNAAMIAAAAFPKLARREFSGLDIAAQANLTLA
HCCCHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA