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The map label for this gene is crp [C]

Identifier: 116625243

GI number: 116625243

Start: 7763347

End: 7764006

Strand: Reverse

Name: crp [C]

Synonym: Acid_6188

Alternate gene names: 116625243

Gene position: 7764006-7763347 (Counterclockwise)

Preceding gene: 116625245

Following gene: 116625240

Centisome position: 77.91

GC content: 50.61

Gene sequence:

>660_bases
ATGAAGGCGATTGAAAAAGTGAAGCCGGCATTCGACCTAAAGACTTTTCTGACAAAGTCCAACAGCAAACGGACAGCAGC
AGATCATCAAGAGGGCGAGATCATTTTCGCTCAAGGTAATCCGGCGGATGCGATCTATTACATCCAGAAAGGCAAGGTCA
AACTCACTGTCATTTCGAGACAGGGGAAGGAGGCCGTGGTCGCAATCCTTGGGGCAGAGGATTTTTTTGGTGAGGGGTGC
CTGGCTGGTCAACCGTTGCGAATGAGTACCGCTGTGTCGATGTCCAAGTGCTCCATCATGAGGCTGAATAAATCGGAAGT
GGTGCGTACGCTCAAAGAGCAGCCGGCCTTTTCGGAGATGTTTGTCGCCCATTTGCTTTCCCGGAATATTCGGTTTGAAG
AGGATCTGGTAGACCAGCTGTTCAACAGCAGTGAGAAGCGGCTTGCACGAGTGCTTCTCCTGTTGGCGAATTTCGGGAAG
GAAGGCACGCCGCAAACGGTCATTCCGAAGATGAGCCAGGAAACGTTGGCAGAGATCGTTGGCACCACTCGCTCAAGAGT
CAGCTTTTTCATGAACCGCTTCCGCAAGCTCGGTTTCATTGAATATAACGGCGGCCTGACGATCCATAGCTCTTTGTTAA
ATGTTGTTCTGCACGATTAA

Upstream 100 bases:

>100_bases
CACCATCATTACTAAAGAATGTTTATGGGCCTGTTTTACACGCAAATACGTTATCCTTGTGCCATACATAAAGGTCAGGA
CTACGGGTGGAAGGTACTGC

Downstream 100 bases:

>100_bases
ACGATGCCGAAGATGCCACGGCTGGGCTTGAATCAGAACCGCGACCGTCAGGGAGCGATCCCCTACGCCAGCATCTCACT
CTTCACCGTCCCCGCGACGT

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; CRP Family Transcriptional Regulator; Transcriptional Regulatory Protein; Global Nitrogen Regulator; Transcription Regulator; CRP Protein; Transcriptional Regulator CAP Family; Regulatory Protein; Response Regulator Receiver; Nitrogen-Responsive Regulatory Protein; Transcriptional Regulator Crp; Crp Family Regulatory Protein; Catabolite Gene Activator; Crp/Fnr Family Transcriptional Repressor; Two-Component System Response Regulator; CAMP Receptor Protein; CAMP Phosphodiesterase; CAMP-Regulatory Protein; Cyclic-AMP Receptor-Like Protein; Transcriptional Regulator Crp/Fnr Family Protein; Global Nitrogen Regulator Ycf

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKAIEKVKPAFDLKTFLTKSNSKRTAADHQEGEIIFAQGNPADAIYYIQKGKVKLTVISRQGKEAVVAILGAEDFFGEGC
LAGQPLRMSTAVSMSKCSIMRLNKSEVVRTLKEQPAFSEMFVAHLLSRNIRFEEDLVDQLFNSSEKRLARVLLLLANFGK
EGTPQTVIPKMSQETLAEIVGTTRSRVSFFMNRFRKLGFIEYNGGLTIHSSLLNVVLHD

Sequences:

>Translated_219_residues
MKAIEKVKPAFDLKTFLTKSNSKRTAADHQEGEIIFAQGNPADAIYYIQKGKVKLTVISRQGKEAVVAILGAEDFFGEGC
LAGQPLRMSTAVSMSKCSIMRLNKSEVVRTLKEQPAFSEMFVAHLLSRNIRFEEDLVDQLFNSSEKRLARVLLLLANFGK
EGTPQTVIPKMSQETLAEIVGTTRSRVSFFMNRFRKLGFIEYNGGLTIHSSLLNVVLHD
>Mature_219_residues
MKAIEKVKPAFDLKTFLTKSNSKRTAADHQEGEIIFAQGNPADAIYYIQKGKVKLTVISRQGKEAVVAILGAEDFFGEGC
LAGQPLRMSTAVSMSKCSIMRLNKSEVVRTLKEQPAFSEMFVAHLLSRNIRFEEDLVDQLFNSSEKRLARVLLLLANFGK
EGTPQTVIPKMSQETLAEIVGTTRSRVSFFMNRFRKLGFIEYNGGLTIHSSLLNVVLHD

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 24446; Mature: 24446

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIEKVKPAFDLKTFLTKSNSKRTAADHQEGEIIFAQGNPADAIYYIQKGKVKLTVISR
CCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCEEEEEEEEC
QGKEAVVAILGAEDFFGEGCLAGQPLRMSTAVSMSKCSIMRLNKSEVVRTLKEQPAFSEM
CCCEEEEEEECCHHHCCCCCCCCCCCCHHHHHHHHHHHHEEECHHHHHHHHHHCCCHHHH
FVAHLLSRNIRFEEDLVDQLFNSSEKRLARVLLLLANFGKEGTPQTVIPKMSQETLAEIV
HHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
GTTRSRVSFFMNRFRKLGFIEYNGGLTIHSSLLNVVLHD
CCHHHHHHHHHHHHHHCCEEEECCCEEEHHHHHHHHHCC
>Mature Secondary Structure
MKAIEKVKPAFDLKTFLTKSNSKRTAADHQEGEIIFAQGNPADAIYYIQKGKVKLTVISR
CCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCEEEEEEEEC
QGKEAVVAILGAEDFFGEGCLAGQPLRMSTAVSMSKCSIMRLNKSEVVRTLKEQPAFSEM
CCCEEEEEEECCHHHCCCCCCCCCCCCHHHHHHHHHHHHEEECHHHHHHHHHHCCCHHHH
FVAHLLSRNIRFEEDLVDQLFNSSEKRLARVLLLLANFGKEGTPQTVIPKMSQETLAEIV
HHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
GTTRSRVSFFMNRFRKLGFIEYNGGLTIHSSLLNVVLHD
CCHHHHHHHHHHHHHHCCEEEECCCEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA