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The map label for this gene is pkn1 [H]

Identifier: 116625199

GI number: 116625199

Start: 7683063

End: 7684112

Strand: Reverse

Name: pkn1 [H]

Synonym: Acid_6144

Alternate gene names: 116625199

Gene position: 7684112-7683063 (Counterclockwise)

Preceding gene: 116625200

Following gene: 116625198

Centisome position: 77.11

GC content: 62.86

Gene sequence:

>1050_bases
ATGTCACGATTGCTCGCAAGGCGCCTGTCCCTCTCGATACTGGCCGCGATTTGGGGCTACGCGCAGGTCACGGGCGGAAA
TCCCAATCCCGCGAAAGAGCGCGCCAATGTGGAGCGAATCCGCGCCCGCATCGAGGCGCACGCGCGCGCCTCTTCGCCGA
GCAAGGGCCCGGTGCGCGTCGTCATTCCTAACACGACGGTGGGCTACGACATGGTGCCGATTCCGGCCGGCGAGTTCGAG
ATGGGCTCGGCCGCTGCAACTCCCGGCGGCAAGATGGATGAACAGCCGCGCCACAAAGTGCGGGTCGATGCCTTCTGGAT
GCAGGCGCACGAAGTGACATGGGATGAGTACCGTCTTTTCATGTTCGAGGGGCGAGGCGGCGCGGCAGTCGCCCAAGATG
CGGCCGTTGACGCCGTGAGCCGTCCGACGCGTCCGTATGTGGAGATGAGTTTTGGAATGGGCATCGAGGGCTTCCCGGCA
ATCAGCATGACGCAGCATGCGGCGAATAAGTACGCCGAGTGGCTCAGCGCAAAGGTCGGCGAGTTCTATCGCTTGCCTAC
CGAAGCGGAATGGGAGTACGCCTGCCGCGCCGGTGCTGCCACGGCCTATCCTTTCGGCGACGACCCGTCGAAGTTGGGAG
ACTACGCCTGGTATGCGGGAAACAGCCAGGGCAAATATCACCCGGTGGGGACGAAGAAGCCCAATGCTTGGGGCCTGTAC
GACATGCTCGGCAACGTGATGGAGTGGACTCTCGATCAATATGCTCCCTACCGGGCGGCTGCCGAATCGAACCCGTGGGT
AAGAGCGACGAAGCCCTATCCGCACGCGGTGCGCGGAGGTTCCTGGAACAACGCCGCGGATATGCTCCGCTGTGCGGCGC
GGGTAGCCTCCGACCCCGATTGGAAGCAGCAGGACCCGCAATTGCCCAAGAGCATCTGGTACGAGACGGACGCACAATGG
CTGGGATTCCGTCTGGTGCGTCCCGCAAAGCTTCCTACCCTGGACGAGATGTATCGCTACTGGAACAGCGGTGTTGAGGA
CGATCAGTAG

Upstream 100 bases:

>100_bases
GCGCTGTTCCCGTCGCACCTGCAGTGGGACGGCAGCCTGGCCGTGCAGCCCATGGCGCAGCCCGGCGTCACCAAACTGCT
GTAGCCACGGATTCAGGCGA

Downstream 100 bases:

>100_bases
CGCGGGCCGCGCGGCGGCGATCTGGCTGGTCTGGTCAGGCTGCGCGCCGGCCTCGGACCTGCGCCTGTACGAATCCGTGG
AGCCGCACATGGGCACGTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSRLLARRLSLSILAAIWGYAQVTGGNPNPAKERANVERIRARIEAHARASSPSKGPVRVVIPNTTVGYDMVPIPAGEFE
MGSAAATPGGKMDEQPRHKVRVDAFWMQAHEVTWDEYRLFMFEGRGGAAVAQDAAVDAVSRPTRPYVEMSFGMGIEGFPA
ISMTQHAANKYAEWLSAKVGEFYRLPTEAEWEYACRAGAATAYPFGDDPSKLGDYAWYAGNSQGKYHPVGTKKPNAWGLY
DMLGNVMEWTLDQYAPYRAAAESNPWVRATKPYPHAVRGGSWNNAADMLRCAARVASDPDWKQQDPQLPKSIWYETDAQW
LGFRLVRPAKLPTLDEMYRYWNSGVEDDQ

Sequences:

>Translated_349_residues
MSRLLARRLSLSILAAIWGYAQVTGGNPNPAKERANVERIRARIEAHARASSPSKGPVRVVIPNTTVGYDMVPIPAGEFE
MGSAAATPGGKMDEQPRHKVRVDAFWMQAHEVTWDEYRLFMFEGRGGAAVAQDAAVDAVSRPTRPYVEMSFGMGIEGFPA
ISMTQHAANKYAEWLSAKVGEFYRLPTEAEWEYACRAGAATAYPFGDDPSKLGDYAWYAGNSQGKYHPVGTKKPNAWGLY
DMLGNVMEWTLDQYAPYRAAAESNPWVRATKPYPHAVRGGSWNNAADMLRCAARVASDPDWKQQDPQLPKSIWYETDAQW
LGFRLVRPAKLPTLDEMYRYWNSGVEDDQ
>Mature_348_residues
SRLLARRLSLSILAAIWGYAQVTGGNPNPAKERANVERIRARIEAHARASSPSKGPVRVVIPNTTVGYDMVPIPAGEFEM
GSAAATPGGKMDEQPRHKVRVDAFWMQAHEVTWDEYRLFMFEGRGGAAVAQDAAVDAVSRPTRPYVEMSFGMGIEGFPAI
SMTQHAANKYAEWLSAKVGEFYRLPTEAEWEYACRAGAATAYPFGDDPSKLGDYAWYAGNSQGKYHPVGTKKPNAWGLYD
MLGNVMEWTLDQYAPYRAAAESNPWVRATKPYPHAVRGGSWNNAADMLRCAARVASDPDWKQQDPQLPKSIWYETDAQWL
GFRLVRPAKLPTLDEMYRYWNSGVEDDQ

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=289, Percent_Identity=29.757785467128, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI38202250, Length=310, Percent_Identity=28.7096774193548, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI257470977, Length=308, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI194248087, Length=267, Percent_Identity=28.8389513108614, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI194248088, Length=282, Percent_Identity=28.3687943262411, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 38950; Mature: 38819

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLLARRLSLSILAAIWGYAQVTGGNPNPAKERANVERIRARIEAHARASSPSKGPVRV
CHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VIPNTTVGYDMVPIPAGEFEMGSAAATPGGKMDEQPRHKVRVDAFWMQAHEVTWDEYRLF
EECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEHHHHCCCCCEEEE
MFEGRGGAAVAQDAAVDAVSRPTRPYVEMSFGMGIEGFPAISMTQHAANKYAEWLSAKVG
EEECCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EFYRLPTEAEWEYACRAGAATAYPFGDDPSKLGDYAWYAGNSQGKYHPVGTKKPNAWGLY
HHEECCCCCCHHHHHHCCCCEECCCCCCHHHHCCEEEECCCCCCCCCCCCCCCCCCCCHH
DMLGNVMEWTLDQYAPYRAAAESNPWVRATKPYPHAVRGGSWNNAADMLRCAARVASDPD
HHHHHHHHHHHHHCCCCHHHCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
WKQQDPQLPKSIWYETDAQWLGFRLVRPAKLPTLDEMYRYWNSGVEDDQ
CCCCCCCCCHHHHCCCCCHHHCEEEECCCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SRLLARRLSLSILAAIWGYAQVTGGNPNPAKERANVERIRARIEAHARASSPSKGPVRV
HHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VIPNTTVGYDMVPIPAGEFEMGSAAATPGGKMDEQPRHKVRVDAFWMQAHEVTWDEYRLF
EECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEHHHHCCCCCEEEE
MFEGRGGAAVAQDAAVDAVSRPTRPYVEMSFGMGIEGFPAISMTQHAANKYAEWLSAKVG
EEECCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EFYRLPTEAEWEYACRAGAATAYPFGDDPSKLGDYAWYAGNSQGKYHPVGTKKPNAWGLY
HHEECCCCCCHHHHHHCCCCEECCCCCCHHHHCCEEEECCCCCCCCCCCCCCCCCCCCHH
DMLGNVMEWTLDQYAPYRAAAESNPWVRATKPYPHAVRGGSWNNAADMLRCAARVASDPD
HHHHHHHHHHHHHCCCCHHHCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
WKQQDPQLPKSIWYETDAQWLGFRLVRPAKLPTLDEMYRYWNSGVEDDQ
CCCCCCCCCHHHHCCCCCHHHCEEEECCCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]