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The map label for this gene is ubiE [C]

Identifier: 116625165

GI number: 116625165

Start: 7637822

End: 7639036

Strand: Reverse

Name: ubiE [C]

Synonym: Acid_6108

Alternate gene names: 116625165

Gene position: 7639036-7637822 (Counterclockwise)

Preceding gene: 116625167

Following gene: 116625163

Centisome position: 76.65

GC content: 60.33

Gene sequence:

>1215_bases
ATGATTTGGCGCCCCCTGCGGACCGGATTGTTGACGGTTCTGGTAGTCGCAGCCCAAAGCGTCGCTTCTGAGCCGTCGCG
CGAGCGATGGCAGCACGTCGATGAGATTTTCAAAGCCGCCGGAATTGGCGCCGGCAGCATAGTCGCCGATGTCGGAGCGG
GCGATGGCTTTCTGACACTGCGGATTGCCCCGATAGTCGGCCAGACGGGACATGTATTCGCTGTCGACATCGCCGACATC
AAATTGCAGCGTTTGAAGGAGCGCGCGGAAGAGGCGCATTTCGGCAATATTGAGATCGTGAAGGGCGAGGAGGGCGACCC
TCGCCTTCCCGCCCGACAACTTGACGCGGTGATCATCCTGAACTCCTATCACGAGATGCCGAGGTTCAAGGAAATACTTC
TGCACCTTCGCGAGCCATTGAAGCCGGGCGGCCGGCTCCTCATCGCGGAACCAGGACCGCTTCCCGCTGAACAGACGCGG
GCAGAGCAGATCGCGCGGCATCACATCGGCTCGAAATTTGTGGCGGATGAAATGGCTCAGGCCGGCTTCGTCATCCTGGA
ACAACGAGAAAGGTTCGCGCAGATCCCGGAAGCCAACTGGTATTCCCTAGTGGTGGGTCAACGCCCCTCTTCGGACGAGG
AATGGGCAGTCGAGATGAAACGCCGTGTGGTGGCCAGTCTGCATTTGCGGAGCGGCGCCGAGGCGGCTGATGTAGGTTGC
GGCGATGGATTCTACACTCTTCCCATGGCGCTTGCTGTTGGTCCCGCGGGTAAGGTGTTGGCGGTGGACATCGATGAGAG
CAGCCCGTCAAAGCTGAAGCAACACCTGACTGAGGGGGGTGTGCGGAACGTCGAACTCGTCCACGGCGCTGAGGATGATC
CACGGCTGCCGCCGGCTCGCCTTGACGTAGTACTTGTTGCGAATGCTTACCACGAAATGCAGGCGCACGAGGCTATGCTC
AGGGGCATCCGTGCCGGGTTGAAACCGGGAGGATTGCTGGTGCTGATGGAGTCTCTATCCGAGGCACGCCAGACGCTGAC
GAGAGCCGCCCAAGTGAAGCGCCACGAACTGAGCCCAGAAACTGCACGGAATGAACTGCAGGAGGCTGGATTCGAGATTG
TCGAGCTGAACGATCCATTCATCCAGCGCGCGGCCGATCAGGAGGGGAAGTCCAGATGGTGGCTTCTGGTTGCGCGCAAA
CCCTCGGGGCAGTAA

Upstream 100 bases:

>100_bases
TGGGAGATTCCGTCTACTGCAGAGCACGACAGAACTGCACGAAACTCCTTTCGGAACAAAGCAGCAATTCGTATATTGCT
GTTGCAGGGTGGAATAAACG

Downstream 100 bases:

>100_bases
AGCACAGTGGACTGGTGCTAGCTACCGATAATGAAGAGCATTCTATCGGTGGTGCCCGCCCCCAAAACTCCAGCGGAGCG
TCAGTTGCTTGCCGTCGCTG

Product: type 11 methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Methyltransferase; SAM-Dependent Methyltransferase; Methyltransferase Family Protein; Methyltransferase UbiE/COQ5 Family; Methylase Involved In Ubiquinone/Menaquinone Biosynthesis; Ubiquinone/Menaquinone Biosynthesis Methyltransferase; Generic Methyltransferase; Methyltransferase Domain Family; Methyltransferase Domain Family Protein; UbiE/COQ5 Methyltransferase; Methylase

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MIWRPLRTGLLTVLVVAAQSVASEPSRERWQHVDEIFKAAGIGAGSIVADVGAGDGFLTLRIAPIVGQTGHVFAVDIADI
KLQRLKERAEEAHFGNIEIVKGEEGDPRLPARQLDAVIILNSYHEMPRFKEILLHLREPLKPGGRLLIAEPGPLPAEQTR
AEQIARHHIGSKFVADEMAQAGFVILEQRERFAQIPEANWYSLVVGQRPSSDEEWAVEMKRRVVASLHLRSGAEAADVGC
GDGFYTLPMALAVGPAGKVLAVDIDESSPSKLKQHLTEGGVRNVELVHGAEDDPRLPPARLDVVLVANAYHEMQAHEAML
RGIRAGLKPGGLLVLMESLSEARQTLTRAAQVKRHELSPETARNELQEAGFEIVELNDPFIQRAADQEGKSRWWLLVARK
PSGQ

Sequences:

>Translated_404_residues
MIWRPLRTGLLTVLVVAAQSVASEPSRERWQHVDEIFKAAGIGAGSIVADVGAGDGFLTLRIAPIVGQTGHVFAVDIADI
KLQRLKERAEEAHFGNIEIVKGEEGDPRLPARQLDAVIILNSYHEMPRFKEILLHLREPLKPGGRLLIAEPGPLPAEQTR
AEQIARHHIGSKFVADEMAQAGFVILEQRERFAQIPEANWYSLVVGQRPSSDEEWAVEMKRRVVASLHLRSGAEAADVGC
GDGFYTLPMALAVGPAGKVLAVDIDESSPSKLKQHLTEGGVRNVELVHGAEDDPRLPPARLDVVLVANAYHEMQAHEAML
RGIRAGLKPGGLLVLMESLSEARQTLTRAAQVKRHELSPETARNELQEAGFEIVELNDPFIQRAADQEGKSRWWLLVARK
PSGQ
>Mature_404_residues
MIWRPLRTGLLTVLVVAAQSVASEPSRERWQHVDEIFKAAGIGAGSIVADVGAGDGFLTLRIAPIVGQTGHVFAVDIADI
KLQRLKERAEEAHFGNIEIVKGEEGDPRLPARQLDAVIILNSYHEMPRFKEILLHLREPLKPGGRLLIAEPGPLPAEQTR
AEQIARHHIGSKFVADEMAQAGFVILEQRERFAQIPEANWYSLVVGQRPSSDEEWAVEMKRRVVASLHLRSGAEAADVGC
GDGFYTLPMALAVGPAGKVLAVDIDESSPSKLKQHLTEGGVRNVELVHGAEDDPRLPPARLDVVLVANAYHEMQAHEAML
RGIRAGLKPGGLLVLMESLSEARQTLTRAAQVKRHELSPETARNELQEAGFEIVELNDPFIQRAADQEGKSRWWLLVARK
PSGQ

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 44352; Mature: 44352

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWRPLRTGLLTVLVVAAQSVASEPSRERWQHVDEIFKAAGIGAGSIVADVGAGDGFLTL
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCEEEE
RIAPIVGQTGHVFAVDIADIKLQRLKERAEEAHFGNIEIVKGEEGDPRLPARQLDAVIIL
EEEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCEEEEE
NSYHEMPRFKEILLHLREPLKPGGRLLIAEPGPLPAEQTRAEQIARHHIGSKFVADEMAQ
CCHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
AGFVILEQRERFAQIPEANWYSLVVGQRPSSDEEWAVEMKRRVVASLHLRSGAEAADVGC
CCEEEEHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GDGFYTLPMALAVGPAGKVLAVDIDESSPSKLKQHLTEGGVRNVELVHGAEDDPRLPPAR
CCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCC
LDVVLVANAYHEMQAHEAMLRGIRAGLKPGGLLVLMESLSEARQTLTRAAQVKRHELSPE
EEEEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
TARNELQEAGFEIVELNDPFIQRAADQEGKSRWWLLVARKPSGQ
HHHHHHHHCCCEEEECCCHHHHHHCCCCCCCEEEEEEEECCCCC
>Mature Secondary Structure
MIWRPLRTGLLTVLVVAAQSVASEPSRERWQHVDEIFKAAGIGAGSIVADVGAGDGFLTL
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHEEECCCCCCEEEE
RIAPIVGQTGHVFAVDIADIKLQRLKERAEEAHFGNIEIVKGEEGDPRLPARQLDAVIIL
EEEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCEEEEE
NSYHEMPRFKEILLHLREPLKPGGRLLIAEPGPLPAEQTRAEQIARHHIGSKFVADEMAQ
CCHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
AGFVILEQRERFAQIPEANWYSLVVGQRPSSDEEWAVEMKRRVVASLHLRSGAEAADVGC
CCEEEEHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GDGFYTLPMALAVGPAGKVLAVDIDESSPSKLKQHLTEGGVRNVELVHGAEDDPRLPPAR
CCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCC
LDVVLVANAYHEMQAHEAMLRGIRAGLKPGGLLVLMESLSEARQTLTRAAQVKRHELSPE
EEEEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
TARNELQEAGFEIVELNDPFIQRAADQEGKSRWWLLVARKPSGQ
HHHHHHHHCCCEEEECCCHHHHHHCCCCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA