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The map label for this gene is ywaD [H]

Identifier: 116625167

GI number: 116625167

Start: 7641619

End: 7643124

Strand: Reverse

Name: ywaD [H]

Synonym: Acid_6111

Alternate gene names: 116625167

Gene position: 7643124-7641619 (Counterclockwise)

Preceding gene: 116625168

Following gene: 116625165

Centisome position: 76.69

GC content: 62.95

Gene sequence:

>1506_bases
ATGCCCGCAGGTCCCTTTCGCTTGGTCGTAGTCTTCTGTGCGAGCGCACTGCTGATTGCCCAGGACGCGCAGTTGACACG
ACTGCACGCCGATCTGGACTTCCTCACGTCCGACGTCCTGGCAGGCCGCGTCTCCCTTTCCCCGCAAGCGGAGATTGCGG
CGCGGTTCATTGACGCCGAGTTCCGCAAGGCCGGGCTGACTTCCCAACTGCAGGCCTTTCCTGTGGTCGGCTATCGGTCC
GATCCGAAACAGCGCCAGTTGCTGCTGACACGCGGCGGGGCCAGCCGGCCGCTGCACGCGTTCACCGGCGGATTCTATCG
CGACATCGCGGTCCGGGCGCCCGTAGTCTTCGCCGGATACGGGATTACGGCCCTCGAGTACGCGTACGACGACTACGCTA
CGGTCAACGCCAGCGGGAGAATCGTGCTGATCTTCGATCACGAGCCGCAGGAAGACAGCGCGGCCTCAGTGTTCAACGGT
ACCGGCCACACCTTGCATGCCGGCCGGGCGGCCAAGGTCCTGAACGCGCGCCGGCACGGCGCCTTGGCCGTGCTGATCGC
TACCGAGCCCAGCCACCACAGCTACATTTTGGCCAGCCCGCAGAGGGCTCCCTTGCGTGCCTCGGCTCCGCCGCAAGCGA
TCGATGACCCGGCGCAGATTCCGGCCTTTACGCTGAGCGAAGCCGATGTCAAAGATCTGCTGTCGGTCACCGGTCGCACG
CCTGTAGAATTGCAGGATGCGATTGACGCCTCCCTCCGGCCGCAGTCGCAACCGCTGCGCGATACCGAGGTGGAAATCCG
GGCATCCAACGCGGAACAGCATCGCGGATCCTCGTTGAATGCGATCGGCCTGCTGGAAGGCAGCGATCCGGAGTTGAAAT
CAGAGACCATCCTGATCAGCGCTCATTACGATCACTTGGGCGTGCAGAACGAGCACCTGTACCCGGGCGCCAATGATAAC
GCATCCGGCACAGCCGCGGTGATGGAGTTGGCCCGGCTGCTCGCTAAGGAGCCGCGACCGAGGCGGAGTATTCTCTTCGC
CGTCTTCGGGTCCGAGGAGCAGCTCATGCTCGGGTCGTTCTACTACACCGCACATCCCCTACGATCGCTGGCGACCACGC
GCGCGGTTCTGAATCTCGACATGATTGCGCGCGACGATATCGAGGGCGCCTCCAACCGGATCCACCTGGTCGGCACTTAT
TACAGCCGTGAACTGCTGGCCGCCATCCGCGCTCAGAATCGAAAGACCGGCCTGGATCTGAGCACCGAACTCGACGCAGA
CCAGGCGTTGAACGTGCTTTTCCGGTGCGATCATCTGCCGTTCTTGCTTTCCGGTTTACCGGCCGTATGGTTCTTCGGCG
GTTTTCATCCCGGATATCACGAACCCTCTGATGTCGTGGAGAAACTGAACCTCCCGAAACTCCAGAACGTGATCCGGCTG
GCGCACGACTCTGCCGTGGCACTCGCGGACACGTCGGCGCCGCCCCAATTTGGAATCCCGAAGTGA

Upstream 100 bases:

>100_bases
AGGGCCGGGGGTTCGTAGCTACCGATAATACGGGTTATCGTGCCTTGTTCCCATGCCGTATCTCTACGATATTCCCCGAA
CGATCCGGCTACTATGAAGC

Downstream 100 bases:

>100_bases
GCCGCCGCTCAGGAGGATCGGAAACGGCCGTTCATCTTTTCCAATGGTTCGGCTACAGAACCGCGGTGGACCGCAGCGTG
GTTGAAGAACTCGAAGGGGG

Product: peptidase M28

Products: NA

Alternate protein names: Arginyl aminopeptidase; BSAP; Leucyl aminopeptidase [H]

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MPAGPFRLVVVFCASALLIAQDAQLTRLHADLDFLTSDVLAGRVSLSPQAEIAARFIDAEFRKAGLTSQLQAFPVVGYRS
DPKQRQLLLTRGGASRPLHAFTGGFYRDIAVRAPVVFAGYGITALEYAYDDYATVNASGRIVLIFDHEPQEDSAASVFNG
TGHTLHAGRAAKVLNARRHGALAVLIATEPSHHSYILASPQRAPLRASAPPQAIDDPAQIPAFTLSEADVKDLLSVTGRT
PVELQDAIDASLRPQSQPLRDTEVEIRASNAEQHRGSSLNAIGLLEGSDPELKSETILISAHYDHLGVQNEHLYPGANDN
ASGTAAVMELARLLAKEPRPRRSILFAVFGSEEQLMLGSFYYTAHPLRSLATTRAVLNLDMIARDDIEGASNRIHLVGTY
YSRELLAAIRAQNRKTGLDLSTELDADQALNVLFRCDHLPFLLSGLPAVWFFGGFHPGYHEPSDVVEKLNLPKLQNVIRL
AHDSAVALADTSAPPQFGIPK

Sequences:

>Translated_501_residues
MPAGPFRLVVVFCASALLIAQDAQLTRLHADLDFLTSDVLAGRVSLSPQAEIAARFIDAEFRKAGLTSQLQAFPVVGYRS
DPKQRQLLLTRGGASRPLHAFTGGFYRDIAVRAPVVFAGYGITALEYAYDDYATVNASGRIVLIFDHEPQEDSAASVFNG
TGHTLHAGRAAKVLNARRHGALAVLIATEPSHHSYILASPQRAPLRASAPPQAIDDPAQIPAFTLSEADVKDLLSVTGRT
PVELQDAIDASLRPQSQPLRDTEVEIRASNAEQHRGSSLNAIGLLEGSDPELKSETILISAHYDHLGVQNEHLYPGANDN
ASGTAAVMELARLLAKEPRPRRSILFAVFGSEEQLMLGSFYYTAHPLRSLATTRAVLNLDMIARDDIEGASNRIHLVGTY
YSRELLAAIRAQNRKTGLDLSTELDADQALNVLFRCDHLPFLLSGLPAVWFFGGFHPGYHEPSDVVEKLNLPKLQNVIRL
AHDSAVALADTSAPPQFGIPK
>Mature_500_residues
PAGPFRLVVVFCASALLIAQDAQLTRLHADLDFLTSDVLAGRVSLSPQAEIAARFIDAEFRKAGLTSQLQAFPVVGYRSD
PKQRQLLLTRGGASRPLHAFTGGFYRDIAVRAPVVFAGYGITALEYAYDDYATVNASGRIVLIFDHEPQEDSAASVFNGT
GHTLHAGRAAKVLNARRHGALAVLIATEPSHHSYILASPQRAPLRASAPPQAIDDPAQIPAFTLSEADVKDLLSVTGRTP
VELQDAIDASLRPQSQPLRDTEVEIRASNAEQHRGSSLNAIGLLEGSDPELKSETILISAHYDHLGVQNEHLYPGANDNA
SGTAAVMELARLLAKEPRPRRSILFAVFGSEEQLMLGSFYYTAHPLRSLATTRAVLNLDMIARDDIEGASNRIHLVGTYY
SRELLAAIRAQNRKTGLDLSTELDADQALNVLFRCDHLPFLLSGLPAVWFFGGFHPGYHEPSDVVEKLNLPKLQNVIRLA
HDSAVALADTSAPPQFGIPK

Specific function: Catalyzes the hydrolysis of a range of N-terminal amino acids [H]

COG id: COG2234

COG function: function code R; Predicted aminopeptidases

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M28 family. M28B subfamily [H]

Homologues:

Organism=Homo sapiens, GI57232740, Length=261, Percent_Identity=28.3524904214559, Blast_Score=74, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007484
- InterPro:   IPR003137 [H]

Pfam domain/function: PF02225 PA; PF04389 Peptidase_M28 [H]

EC number: =3.4.11.6; =3.4.11.10 [H]

Molecular weight: Translated: 54318; Mature: 54187

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAGPFRLVVVFCASALLIAQDAQLTRLHADLDFLTSDVLAGRVSLSPQAEIAARFIDAE
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCEECCCCHHHHHHHHHHHH
FRKAGLTSQLQAFPVVGYRSDPKQRQLLLTRGGASRPLHAFTGGFYRDIAVRAPVVFAGY
HHHCCCCHHHHHEEEECCCCCCHHHEEEEECCCCCCCHHHHCCCHHHHHHHCCCEEEECC
GITALEYAYDDYATVNASGRIVLIFDHEPQEDSAASVFNGTGHTLHAGRAAKVLNARRHG
CCEEEEEECCCCEEECCCCEEEEEECCCCCCCCHHHHCCCCCCEEECCHHHHHHHHCCCC
ALAVLIATEPSHHSYILASPQRAPLRASAPPQAIDDPAQIPAFTLSEADVKDLLSVTGRT
CEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCHHCCEEEECHHHHHHHHHHCCCC
PVELQDAIDASLRPQSQPLRDTEVEIRASNAEQHRGSSLNAIGLLEGSDPELKSETILIS
CEEHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHCCCCCCEEEEECCCCCCCCCCEEEEE
AHYDHLGVQNEHLYPGANDNASGTAAVMELARLLAKEPRPRRSILFAVFGSEEQLMLGSF
ECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEE
YYTAHPLRSLATTRAVLNLDMIARDDIEGASNRIHLVGTYYSRELLAAIRAQNRKTGLDL
HHHHHHHHHHHHHHHHHEEHHHCCCCCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCC
STELDADQALNVLFRCDHLPFLLSGLPAVWFFGGFHPGYHEPSDVVEKLNLPKLQNVIRL
CCCCCHHHHHHHHHHCCCCHHHHHCCCHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHH
AHDSAVALADTSAPPQFGIPK
HCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
PAGPFRLVVVFCASALLIAQDAQLTRLHADLDFLTSDVLAGRVSLSPQAEIAARFIDAE
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCEECCCCHHHHHHHHHHHH
FRKAGLTSQLQAFPVVGYRSDPKQRQLLLTRGGASRPLHAFTGGFYRDIAVRAPVVFAGY
HHHCCCCHHHHHEEEECCCCCCHHHEEEEECCCCCCCHHHHCCCHHHHHHHCCCEEEECC
GITALEYAYDDYATVNASGRIVLIFDHEPQEDSAASVFNGTGHTLHAGRAAKVLNARRHG
CCEEEEEECCCCEEECCCCEEEEEECCCCCCCCHHHHCCCCCCEEECCHHHHHHHHCCCC
ALAVLIATEPSHHSYILASPQRAPLRASAPPQAIDDPAQIPAFTLSEADVKDLLSVTGRT
CEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCHHCCEEEECHHHHHHHHHHCCCC
PVELQDAIDASLRPQSQPLRDTEVEIRASNAEQHRGSSLNAIGLLEGSDPELKSETILIS
CEEHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHCCCCCCEEEEECCCCCCCCCCEEEEE
AHYDHLGVQNEHLYPGANDNASGTAAVMELARLLAKEPRPRRSILFAVFGSEEQLMLGSF
ECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEE
YYTAHPLRSLATTRAVLNLDMIARDDIEGASNRIHLVGTYYSRELLAAIRAQNRKTGLDL
HHHHHHHHHHHHHHHHHEEHHHCCCCCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCC
STELDADQALNVLFRCDHLPFLLSGLPAVWFFGGFHPGYHEPSDVVEKLNLPKLQNVIRL
CCCCCHHHHHHHHHHCCCCHHHHHCCCHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHH
AHDSAVALADTSAPPQFGIPK
HCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377; 1806041 [H]