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The map label for this gene is macB2 [H]

Identifier: 116625002

GI number: 116625002

Start: 7436567

End: 7439053

Strand: Direct

Name: macB2 [H]

Synonym: Acid_5932

Alternate gene names: 116625002

Gene position: 7436567-7439053 (Clockwise)

Preceding gene: 116625001

Following gene: 116625005

Centisome position: 74.62

GC content: 62.93

Gene sequence:

>2487_bases
ATGAATCGACTCCGCTTCGCCGTTCGCAGCCTGCTGAAGGCGCCGATGCTCAGTCTGGTGGTGATTCTCTCGGTTTCACT
GGGAATCGGCGCCAATACCGCAATTTTTTCGCTGATGCACCAGATCCTGCTGAATTCCCTGCCGGTGGAACGGCCTGATG
AATTGGTGGTGCTTTCCTCGCCCGAGCGATTCAAGGGCGGCCGTACTTCCAACAACGATGCGGGCGGCACGGAACTGATT
TTCAGCTACCCGATGTTCCGGGAGTTGGAGAAGCGACATCAAGGCCTGAGCAGGCTCGGTGCTTTCCGTCAACTGGAAGC
CAACATCGCCTTTCAGAAGCAGACCACCTCGGGCGCGATGCTGTTAGTGTCGGGCGGCTACTTTCCCACGCTCGGCGTGC
GTCCGCTGATGGGGCGCACGATTGGGCCGGACGACGACGCGGGTCCCGGCAATCCGGTCGCGGTGTTGAGTTATGCGTAC
TGGCAGGATCATCTGGGTGGGGAACGCTCTGTGTTGAATCAGCCCATCAAGGTGAACGGCCAGCTGTTCACCATCGTCGG
CGTGACGCCGAAGGCATTCACCGGGACCACGATCGGCAGCGAGCCTTCGATCTTCGTGCCGCTGGTTTTCAAACCGCTGC
TGACTCCGAATTGGAACGGCACGGACCGGTGGAGCGACTATTGGCTGTACACGATCGCACGGCTGGAGCGCGGCGTCTCG
CGGGGACAGGTGGAAGGGTCGCTGAACAGTATTTACGCGGGATTGGTGGAGCAGCAATCCAAGATGCCCGGCTTCTACTA
CCAGAAGCAGCTGGATCGCTTCCTGCACGGGCGGCTCTCGTTAAAGGAAGGCAGTCAGGGAAACAGCGAATTTCGCGACA
GCACGAAGACGCCGCTGATCATCCTTATGTGCGCGAGCGTGCTGGTGCTGCTGATCGCAATGGCGAATTCGGCGAACCTG
CTGCTCGCGCGCTCCGCGCAACGGCGGCGCGAAATGGCGATCCGCGCGGCAATGGGCGCGGGACGCGGTGAGCTGTTGGC
GCAAATGCTCACCGAAGCATTGGTGCTGGCCTTCGCCGGCGGCTTGGCCGGGCTGGCATTCGCGGTGGTTACGCTCAAAC
TGCTGATCGCCGAAATGGCGGGGGATGGCGCGATCCATTTCATCGATGCCTCGCTGGAATGGCCGGTGCTGCTCTTCGGC
CTCGGGCTCGCACTGGTCACCGGTTTGGTATTCGGGCTGTATCCCGCATGGGAAGCGGCGCGTGCGTCGGCGGCGGTTAC
GCTCAAAAACGAATCGGGGCAAAGCTCGGGGACGGCGGGCGCGGCGCGCGTGCGCAAGGTGCTGGTCTGCGCGCAGGTGA
TGGTGTCGGCGGTGCTGCTGATTCCCACGGGACTGTTCCTGAAGAGCCTGGTCAACCTGATGCACGTGGATCTCGGGATG
AAGACCGAGAACCTGATTGGGTTCACGATATCGCCCGCGCTGAACGGATACAAGACCGAGCAGACGCGGGCGCTGTTCGA
ACGCGTGGAGAGTGAGATGGCCGCTATTCCGGGCGCCAAATCCGTGGCCGCCGCGATGGTGCCGCTGATCGCCGGCAACA
ACTGGGGCAACGACGTCCACGTGGAGGGCGCCAAGGATACTCAGGCCAACAACAATTCCCGCATGAACGAAATCGGCCCG
GCCTTCTTCGGCAAGTTGGGAATTCCGCTGATTGCGGGACGCGAGTTCACGGATGCCGACACTGCCGCGGGGCCTCCGGT
GGCGATTGTGAATGAGACGTTCGTGAAACGGTTCCTCGATGGGCGGAACCCGATCGGCGTGCGTTTCACGGGCGGCGGCC
CGGGCGCCAGGACCATCGTGGGCGTGGTCAAGGACAGTCATTACTCGAGCGTGAAGCAGGCCGTGCCTCCGCTCTACTAC
ACGCCCTGGCGGCAGGACAAGCAGCTCAACTCGCTCGAATTCTACGTGCGATCAGCGCTGCCCGAGAGCCAGATGGTGCC
GCAGATCCGGCGTGTGATGGCATCTCTCGACCGGGATCTTCCGCTGCAAGACTTGCGCACGCTGGATCAGCAGATCAACC
GCAATATTCAGACGGATCGATTGGTGCTGCAACTGGCCGGCGTTTTCGCGGGGCTGGCCACGCTGCTGGCGATGCTCGGG
CTTTATGGAGTGATGGCGCATTCGGTGACGCGTCGGACGCGCGAGATTGGGATCCGGATGGCGCTGGGCGCGGCTCCCGG
GAAGATTCGGGTGATGGTGATGCGCGAACTGCTGTGGATTTTGGTCGCGGGGCTTGTGACCGGCGTTCCGGCCGCGATGC
TGCTGGCGCAGTACACGGAGACGCAGTTGTTCGGCGTCAAGGCGCGCGATGTGATGGTGGTCGCGGGTGCGGTGCTGGCG
CTGACGCTGACCGCGGTGGCGGCGGGATATCTGCCGGCTCGCCGCGCGTCGCGGGTCAATCCGCTGGAAGCGCTCAGGTG
GGAATGA

Upstream 100 bases:

>100_bases
CGTGCGCCGCATCGTAATCGCCATCGGGTTCGGTATGGCGATTTCCCTTTTTGTCAAAAAATAGGTCACGTTTGGCCAAC
CGCGGCGTATATATACCTGT

Downstream 100 bases:

>100_bases
CGCCGGCGCCCTACGCGAGCGCGGGCCGGTCCACCGGGATACCGGCGGCGGCGAGGATGGCCTCGACCTCGGCGGGGCGC
AGGCGGGTGGCATCGTAATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 828; Mature: 828

Protein sequence:

>828_residues
MNRLRFAVRSLLKAPMLSLVVILSVSLGIGANTAIFSLMHQILLNSLPVERPDELVVLSSPERFKGGRTSNNDAGGTELI
FSYPMFRELEKRHQGLSRLGAFRQLEANIAFQKQTTSGAMLLVSGGYFPTLGVRPLMGRTIGPDDDAGPGNPVAVLSYAY
WQDHLGGERSVLNQPIKVNGQLFTIVGVTPKAFTGTTIGSEPSIFVPLVFKPLLTPNWNGTDRWSDYWLYTIARLERGVS
RGQVEGSLNSIYAGLVEQQSKMPGFYYQKQLDRFLHGRLSLKEGSQGNSEFRDSTKTPLIILMCASVLVLLIAMANSANL
LLARSAQRRREMAIRAAMGAGRGELLAQMLTEALVLAFAGGLAGLAFAVVTLKLLIAEMAGDGAIHFIDASLEWPVLLFG
LGLALVTGLVFGLYPAWEAARASAAVTLKNESGQSSGTAGAARVRKVLVCAQVMVSAVLLIPTGLFLKSLVNLMHVDLGM
KTENLIGFTISPALNGYKTEQTRALFERVESEMAAIPGAKSVAAAMVPLIAGNNWGNDVHVEGAKDTQANNNSRMNEIGP
AFFGKLGIPLIAGREFTDADTAAGPPVAIVNETFVKRFLDGRNPIGVRFTGGGPGARTIVGVVKDSHYSSVKQAVPPLYY
TPWRQDKQLNSLEFYVRSALPESQMVPQIRRVMASLDRDLPLQDLRTLDQQINRNIQTDRLVLQLAGVFAGLATLLAMLG
LYGVMAHSVTRRTREIGIRMALGAAPGKIRVMVMRELLWILVAGLVTGVPAAMLLAQYTETQLFGVKARDVMVVAGAVLA
LTLTAVAAGYLPARRASRVNPLEALRWE

Sequences:

>Translated_828_residues
MNRLRFAVRSLLKAPMLSLVVILSVSLGIGANTAIFSLMHQILLNSLPVERPDELVVLSSPERFKGGRTSNNDAGGTELI
FSYPMFRELEKRHQGLSRLGAFRQLEANIAFQKQTTSGAMLLVSGGYFPTLGVRPLMGRTIGPDDDAGPGNPVAVLSYAY
WQDHLGGERSVLNQPIKVNGQLFTIVGVTPKAFTGTTIGSEPSIFVPLVFKPLLTPNWNGTDRWSDYWLYTIARLERGVS
RGQVEGSLNSIYAGLVEQQSKMPGFYYQKQLDRFLHGRLSLKEGSQGNSEFRDSTKTPLIILMCASVLVLLIAMANSANL
LLARSAQRRREMAIRAAMGAGRGELLAQMLTEALVLAFAGGLAGLAFAVVTLKLLIAEMAGDGAIHFIDASLEWPVLLFG
LGLALVTGLVFGLYPAWEAARASAAVTLKNESGQSSGTAGAARVRKVLVCAQVMVSAVLLIPTGLFLKSLVNLMHVDLGM
KTENLIGFTISPALNGYKTEQTRALFERVESEMAAIPGAKSVAAAMVPLIAGNNWGNDVHVEGAKDTQANNNSRMNEIGP
AFFGKLGIPLIAGREFTDADTAAGPPVAIVNETFVKRFLDGRNPIGVRFTGGGPGARTIVGVVKDSHYSSVKQAVPPLYY
TPWRQDKQLNSLEFYVRSALPESQMVPQIRRVMASLDRDLPLQDLRTLDQQINRNIQTDRLVLQLAGVFAGLATLLAMLG
LYGVMAHSVTRRTREIGIRMALGAAPGKIRVMVMRELLWILVAGLVTGVPAAMLLAQYTETQLFGVKARDVMVVAGAVLA
LTLTAVAAGYLPARRASRVNPLEALRWE
>Mature_828_residues
MNRLRFAVRSLLKAPMLSLVVILSVSLGIGANTAIFSLMHQILLNSLPVERPDELVVLSSPERFKGGRTSNNDAGGTELI
FSYPMFRELEKRHQGLSRLGAFRQLEANIAFQKQTTSGAMLLVSGGYFPTLGVRPLMGRTIGPDDDAGPGNPVAVLSYAY
WQDHLGGERSVLNQPIKVNGQLFTIVGVTPKAFTGTTIGSEPSIFVPLVFKPLLTPNWNGTDRWSDYWLYTIARLERGVS
RGQVEGSLNSIYAGLVEQQSKMPGFYYQKQLDRFLHGRLSLKEGSQGNSEFRDSTKTPLIILMCASVLVLLIAMANSANL
LLARSAQRRREMAIRAAMGAGRGELLAQMLTEALVLAFAGGLAGLAFAVVTLKLLIAEMAGDGAIHFIDASLEWPVLLFG
LGLALVTGLVFGLYPAWEAARASAAVTLKNESGQSSGTAGAARVRKVLVCAQVMVSAVLLIPTGLFLKSLVNLMHVDLGM
KTENLIGFTISPALNGYKTEQTRALFERVESEMAAIPGAKSVAAAMVPLIAGNNWGNDVHVEGAKDTQANNNSRMNEIGP
AFFGKLGIPLIAGREFTDADTAAGPPVAIVNETFVKRFLDGRNPIGVRFTGGGPGARTIVGVVKDSHYSSVKQAVPPLYY
TPWRQDKQLNSLEFYVRSALPESQMVPQIRRVMASLDRDLPLQDLRTLDQQINRNIQTDRLVLQLAGVFAGLATLLAMLG
LYGVMAHSVTRRTREIGIRMALGAAPGKIRVMVMRELLWILVAGLVTGVPAAMLLAQYTETQLFGVKARDVMVVAGAVLA
LTLTAVAAGYLPARRASRVNPLEALRWE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=183, Percent_Identity=27.8688524590164, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 89448; Mature: 89448

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLRFAVRSLLKAPMLSLVVILSVSLGIGANTAIFSLMHQILLNSLPVERPDELVVLSS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECC
PERFKGGRTSNNDAGGTELIFSYPMFRELEKRHQGLSRLGAFRQLEANIAFQKQTTSGAM
CHHHCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEE
LLVSGGYFPTLGVRPLMGRTIGPDDDAGPGNPVAVLSYAYWQDHLGGERSVLNQPIKVNG
EEEECCCCCCCCCCHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCHHHHCCCEEECC
QLFTIVGVTPKAFTGTTIGSEPSIFVPLVFKPLLTPNWNGTDRWSDYWLYTIARLERGVS
EEEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
RGQVEGSLNSIYAGLVEQQSKMPGFYYQKQLDRFLHGRLSLKEGSQGNSEFRDSTKTPLI
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCHH
ILMCASVLVLLIAMANSANLLLARSAQRRREMAIRAAMGAGRGELLAQMLTEALVLAFAG
HHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
GLAGLAFAVVTLKLLIAEMAGDGAIHFIDASLEWPVLLFGLGLALVTGLVFGLYPAWEAA
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
RASAAVTLKNESGQSSGTAGAARVRKVLVCAQVMVSAVLLIPTGLFLKSLVNLMHVDLGM
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
KTENLIGFTISPALNGYKTEQTRALFERVESEMAAIPGAKSVAAAMVPLIAGNNWGNDVH
CCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEE
VEGAKDTQANNNSRMNEIGPAFFGKLGIPLIAGREFTDADTAAGPPVAIVNETFVKRFLD
ECCCCCCCCCCCCCHHHHCHHHHHHCCCCEEECCCCCCCCCCCCCCEEEHHHHHHHHHHC
GRNPIGVRFTGGGPGARTIVGVVKDSHYSSVKQAVPPLYYTPWRQDKQLNSLEFYVRSAL
CCCCEEEEECCCCCCHHHEEEHHHCCHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHCC
PESQMVPQIRRVMASLDRDLPLQDLRTLDQQINRNIQTDRLVLQLAGVFAGLATLLAMLG
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LYGVMAHSVTRRTREIGIRMALGAAPGKIRVMVMRELLWILVAGLVTGVPAAMLLAQYTE
HHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQLFGVKARDVMVVAGAVLALTLTAVAAGYLPARRASRVNPLEALRWE
HHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHCCC
>Mature Secondary Structure
MNRLRFAVRSLLKAPMLSLVVILSVSLGIGANTAIFSLMHQILLNSLPVERPDELVVLSS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECC
PERFKGGRTSNNDAGGTELIFSYPMFRELEKRHQGLSRLGAFRQLEANIAFQKQTTSGAM
CHHHCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEE
LLVSGGYFPTLGVRPLMGRTIGPDDDAGPGNPVAVLSYAYWQDHLGGERSVLNQPIKVNG
EEEECCCCCCCCCCHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHCCCCHHHHCCCEEECC
QLFTIVGVTPKAFTGTTIGSEPSIFVPLVFKPLLTPNWNGTDRWSDYWLYTIARLERGVS
EEEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
RGQVEGSLNSIYAGLVEQQSKMPGFYYQKQLDRFLHGRLSLKEGSQGNSEFRDSTKTPLI
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCHH
ILMCASVLVLLIAMANSANLLLARSAQRRREMAIRAAMGAGRGELLAQMLTEALVLAFAG
HHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
GLAGLAFAVVTLKLLIAEMAGDGAIHFIDASLEWPVLLFGLGLALVTGLVFGLYPAWEAA
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
RASAAVTLKNESGQSSGTAGAARVRKVLVCAQVMVSAVLLIPTGLFLKSLVNLMHVDLGM
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
KTENLIGFTISPALNGYKTEQTRALFERVESEMAAIPGAKSVAAAMVPLIAGNNWGNDVH
CCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEE
VEGAKDTQANNNSRMNEIGPAFFGKLGIPLIAGREFTDADTAAGPPVAIVNETFVKRFLD
ECCCCCCCCCCCCCHHHHCHHHHHHCCCCEEECCCCCCCCCCCCCCEEEHHHHHHHHHHC
GRNPIGVRFTGGGPGARTIVGVVKDSHYSSVKQAVPPLYYTPWRQDKQLNSLEFYVRSAL
CCCCEEEEECCCCCCHHHEEEHHHCCHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHCC
PESQMVPQIRRVMASLDRDLPLQDLRTLDQQINRNIQTDRLVLQLAGVFAGLATLLAMLG
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LYGVMAHSVTRRTREIGIRMALGAAPGKIRVMVMRELLWILVAGLVTGVPAAMLLAQYTE
HHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQLFGVKARDVMVVAGAVLALTLTAVAAGYLPARRASRVNPLEALRWE
HHEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]