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The map label for this gene is fadN [H]

Identifier: 116624772

GI number: 116624772

Start: 7134950

End: 7137334

Strand: Reverse

Name: fadN [H]

Synonym: Acid_5696

Alternate gene names: 116624772

Gene position: 7137334-7134950 (Counterclockwise)

Preceding gene: 116624773

Following gene: 116624771

Centisome position: 71.62

GC content: 65.03

Gene sequence:

>2385_bases
ATGAGCGTTGAAACAGCGATGCAACCGGCGGCGTCGGGAGAGTCTTCTTCCGGACGCTCGCCCGCACCGGTGATCCGCAA
AGCGGCGGTGCTGGGGGCCGGAACCATGGGAGCGCGGATTGCGGCACACCTGGCGAATGCCGGGCTGCCCGTGGTGCTTC
TCGATATGGCTACGGCGGAAGGGGCGCGCAGCAAGATCGCCGCGCAGGCGCTGGAGGACCTCAAGAAGAGCAAGCCGGCG
GCGTTTTACGATTCGGCTTACGCGGCGCACATCATCGTCGGGAACTTCGAGGACGATATGGCGCTGCTGGCGGATTGCGA
CTGGGTAATCGAAGCGGTGACGGAGAATCTCGCGATCAAGCAGTCGCTGCTCGACAAGGCCGTGCCGCATCTGAAGGCAG
GCGCGATTCTGACGACGAATACGAGCGGCCTGCCGGTGGCGCAGATCGCGGCCAAACTCCCGGCTGACGTGCGGCGGCGT
TGGTTTGGCACGCACTTTTTCAATCCGCCACGCTACATGCGGCTGCTGGAGATTATCCCAACTCCGGACGCGGACGCGGC
GGCGATTGCGGCGATCTCGCATTTCGCCGATGTGCTGCTGGGGAAGGAAGTGGTGTTCGCGCGCGACACGCCCAATTTCA
TCGCCAACCGGATCGGCGTGTTCATCATGCTGGAGGCGGTCCGGCTGATGCAGGAAGAAGACCTGACCATCGAAGAGGTG
GACGTGCTGACGGGCAGCGTGATCGGCTGGCCGCGCACGGGGACGTTCCGCCTGGCGGACATGGTGGGAATCGACGTGCT
GGCGCACGTGGCTTCGAATTTCGCGGGTTCGGGGACCATGCCGCCGTTCGTGAAGGCGATGCTGGAGCGGCGCTGGCTGG
GCGATAAAACCAGGCAGGGCTTCTACAAGAAAGAGAAGGACGCAGAGGGCAAAGAGATCCGGCTGGTGCTGGACTGGAAG
ACGCTGGAGTACGTTCCGGCGGTGCGTCCGAAGATCGCGTCGATCGAGATGGCGAAGAATGCCGAGCAGTTGCCGGCGCG
GCTGCAGCAGTTGCTGGCCGGGGATGTACGCAAGGACAAGGCGGCGCGATTCCACTGGCGGCTGCTGACGGGCCTGTGGA
ACGATGCGGCGGATTGTCTGCCGGAGATCGCCGACGACGCGAGCAGCGTGGACCGCGCGATGCGCGCGGGCTTCAACTGG
GAGATGGGACCGTTCCAACTGTGGGATGCGGCCGGCGTGCAGGAAATCGTGAAGAGGATGCGGGCCGCCGGCGAGCGGGT
GAGTCCGGTCGCCGAGAGCGTGGCCCACTGGTACCGGGCGCACAGCCGCGAGGTCTTCGACGTGGTGAGCGGCGGCTACC
GGCCGGTGAAGGAGGCCGCGGGTATCGGGCGGATTGCGAAGTTCCGCGCGTCGAATGGGGTGGTGCGGCAGAATCCGGGG
GCGTCGCTCGTGGATCTGGGCGATGGCGTGGCGTGCCTGGAAATGCATTCGAAGAAGAACGCAGTGGGCGAAGACATCGT
CCGGCTGATCACGGAGACGTTCTCGCCGGGCAGCGACGCGGTACGGAATTTCGAGGCCTTCGTGGTCAGCAATGATTCCG
AGCACTTCTCAGTAGGCGCGAACCTGATGCAACTGCTGTTGAGCGCGCAGGAGGAGGAGTGGGACGACGTGGATTTCGCC
ATACGCGGATTCCAGCGTATGACGGCGGCGATCAAATTCTGCCCGCGTCCTGTAGTGGTGGCGCCGTATTCATTCTGCCT
GGGCGGCGGCGCGGAGATCGCGATGCACGGCGCCCAGCGGCAGGCGCACGCGGAATTGTACATGGGACTGGTGGAGACTG
GGGTCGGCGTGGTACCGGCCGGCGGCGGGTGTAAGGAGATGCTGCTGCGCTCGTTGGATGCGGGCGGTGCCGTGCACGAT
GCCGCGCTGCGCAAGAACTTCGAGACGATTGCGATGGCGAAGGTCTCGACCTCGGCGGTGGAGGCGCGGCGCATGGGCCT
GCTGCTGCCGGCGGACCGGATTACGATGAATCGCGAGCGGCTGCTGCACGACGCCAAACAATCGGCGCGCGAGTTGGCGG
ATGGCGGATATGCGGCGCCGGTGCCGCGCACCGATATCCCGGCGCCGGGGGAAAATCTGCTGGCAACGTTGAAGCTCGGA
GTCCACATGATGCGGCAGGGCGAGTTTATCAGCGATCACGATGTGAAGGTGGCGAACTGGGTGGCGTACGTGTTGTGCGG
CGGTCCGGTGACGCCTGGCACGCTGGTGAGCGAGCAGTACCTGCTGGATCTGGAGCGGGAGGCATTTCTTTCGCTGTGCG
GGGAGAAGAAGACCCAGGAGCGGATCGCGTACACGTTAAAGAGCGGCCGGCCGTTGCGGAACTGA

Upstream 100 bases:

>100_bases
GATGGGGCCCTGTCGCCGGAAGAGATTGCGGCGCAGTTCGCACGTACTTTGACGCAGGGTCTGGCGGCTAAAGGGCAATT
CCCAAAGAGGAGCAATTCGG

Downstream 100 bases:

>100_bases
AATTGGCCGCAGATGAACGCAGATAAACGCGGATAAGAAGAAGCAGGAGAACTTATGAGAGACGCGGTGATTGTGAGCGC
GGTGAGGACGGCGGTGGGCA

Product: 3-hydroxyacyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 794; Mature: 793

Protein sequence:

>794_residues
MSVETAMQPAASGESSSGRSPAPVIRKAAVLGAGTMGARIAAHLANAGLPVVLLDMATAEGARSKIAAQALEDLKKSKPA
AFYDSAYAAHIIVGNFEDDMALLADCDWVIEAVTENLAIKQSLLDKAVPHLKAGAILTTNTSGLPVAQIAAKLPADVRRR
WFGTHFFNPPRYMRLLEIIPTPDADAAAIAAISHFADVLLGKEVVFARDTPNFIANRIGVFIMLEAVRLMQEEDLTIEEV
DVLTGSVIGWPRTGTFRLADMVGIDVLAHVASNFAGSGTMPPFVKAMLERRWLGDKTRQGFYKKEKDAEGKEIRLVLDWK
TLEYVPAVRPKIASIEMAKNAEQLPARLQQLLAGDVRKDKAARFHWRLLTGLWNDAADCLPEIADDASSVDRAMRAGFNW
EMGPFQLWDAAGVQEIVKRMRAAGERVSPVAESVAHWYRAHSREVFDVVSGGYRPVKEAAGIGRIAKFRASNGVVRQNPG
ASLVDLGDGVACLEMHSKKNAVGEDIVRLITETFSPGSDAVRNFEAFVVSNDSEHFSVGANLMQLLLSAQEEEWDDVDFA
IRGFQRMTAAIKFCPRPVVVAPYSFCLGGGAEIAMHGAQRQAHAELYMGLVETGVGVVPAGGGCKEMLLRSLDAGGAVHD
AALRKNFETIAMAKVSTSAVEARRMGLLLPADRITMNRERLLHDAKQSARELADGGYAAPVPRTDIPAPGENLLATLKLG
VHMMRQGEFISDHDVKVANWVAYVLCGGPVTPGTLVSEQYLLDLEREAFLSLCGEKKTQERIAYTLKSGRPLRN

Sequences:

>Translated_794_residues
MSVETAMQPAASGESSSGRSPAPVIRKAAVLGAGTMGARIAAHLANAGLPVVLLDMATAEGARSKIAAQALEDLKKSKPA
AFYDSAYAAHIIVGNFEDDMALLADCDWVIEAVTENLAIKQSLLDKAVPHLKAGAILTTNTSGLPVAQIAAKLPADVRRR
WFGTHFFNPPRYMRLLEIIPTPDADAAAIAAISHFADVLLGKEVVFARDTPNFIANRIGVFIMLEAVRLMQEEDLTIEEV
DVLTGSVIGWPRTGTFRLADMVGIDVLAHVASNFAGSGTMPPFVKAMLERRWLGDKTRQGFYKKEKDAEGKEIRLVLDWK
TLEYVPAVRPKIASIEMAKNAEQLPARLQQLLAGDVRKDKAARFHWRLLTGLWNDAADCLPEIADDASSVDRAMRAGFNW
EMGPFQLWDAAGVQEIVKRMRAAGERVSPVAESVAHWYRAHSREVFDVVSGGYRPVKEAAGIGRIAKFRASNGVVRQNPG
ASLVDLGDGVACLEMHSKKNAVGEDIVRLITETFSPGSDAVRNFEAFVVSNDSEHFSVGANLMQLLLSAQEEEWDDVDFA
IRGFQRMTAAIKFCPRPVVVAPYSFCLGGGAEIAMHGAQRQAHAELYMGLVETGVGVVPAGGGCKEMLLRSLDAGGAVHD
AALRKNFETIAMAKVSTSAVEARRMGLLLPADRITMNRERLLHDAKQSARELADGGYAAPVPRTDIPAPGENLLATLKLG
VHMMRQGEFISDHDVKVANWVAYVLCGGPVTPGTLVSEQYLLDLEREAFLSLCGEKKTQERIAYTLKSGRPLRN
>Mature_793_residues
SVETAMQPAASGESSSGRSPAPVIRKAAVLGAGTMGARIAAHLANAGLPVVLLDMATAEGARSKIAAQALEDLKKSKPAA
FYDSAYAAHIIVGNFEDDMALLADCDWVIEAVTENLAIKQSLLDKAVPHLKAGAILTTNTSGLPVAQIAAKLPADVRRRW
FGTHFFNPPRYMRLLEIIPTPDADAAAIAAISHFADVLLGKEVVFARDTPNFIANRIGVFIMLEAVRLMQEEDLTIEEVD
VLTGSVIGWPRTGTFRLADMVGIDVLAHVASNFAGSGTMPPFVKAMLERRWLGDKTRQGFYKKEKDAEGKEIRLVLDWKT
LEYVPAVRPKIASIEMAKNAEQLPARLQQLLAGDVRKDKAARFHWRLLTGLWNDAADCLPEIADDASSVDRAMRAGFNWE
MGPFQLWDAAGVQEIVKRMRAAGERVSPVAESVAHWYRAHSREVFDVVSGGYRPVKEAAGIGRIAKFRASNGVVRQNPGA
SLVDLGDGVACLEMHSKKNAVGEDIVRLITETFSPGSDAVRNFEAFVVSNDSEHFSVGANLMQLLLSAQEEEWDDVDFAI
RGFQRMTAAIKFCPRPVVVAPYSFCLGGGAEIAMHGAQRQAHAELYMGLVETGVGVVPAGGGCKEMLLRSLDAGGAVHDA
ALRKNFETIAMAKVSTSAVEARRMGLLLPADRITMNRERLLHDAKQSARELADGGYAAPVPRTDIPAPGENLLATLKLGV
HMMRQGEFISDHDVKVANWVAYVLCGGPVTPGTLVSEQYLLDLEREAFLSLCGEKKTQERIAYTLKSGRPLRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI20127408, Length=431, Percent_Identity=29.6983758700696, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI296179429, Length=294, Percent_Identity=31.2925170068027, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI296179427, Length=311, Percent_Identity=29.5819935691318, Blast_Score=117, Evalue=6e-26,
Organism=Homo sapiens, GI261878539, Length=310, Percent_Identity=27.741935483871, Blast_Score=90, Evalue=9e-18,
Organism=Homo sapiens, GI68989263, Length=310, Percent_Identity=27.741935483871, Blast_Score=90, Evalue=1e-17,
Organism=Escherichia coli, GI1787661, Length=466, Percent_Identity=26.1802575107296, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1788682, Length=359, Percent_Identity=27.8551532033426, Blast_Score=90, Evalue=7e-19,
Organism=Escherichia coli, GI1790281, Length=219, Percent_Identity=27.8538812785388, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17549919, Length=294, Percent_Identity=32.9931972789116, Blast_Score=132, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17553560, Length=292, Percent_Identity=31.1643835616438, Blast_Score=123, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17558304, Length=436, Percent_Identity=29.1284403669725, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17563036, Length=311, Percent_Identity=29.903536977492, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17508951, Length=416, Percent_Identity=28.3653846153846, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17508953, Length=416, Percent_Identity=28.3653846153846, Blast_Score=106, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI25144276, Length=322, Percent_Identity=31.3664596273292, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71985923, Length=400, Percent_Identity=24.75, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71985930, Length=417, Percent_Identity=24.9400479616307, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24583077, Length=418, Percent_Identity=28.2296650717703, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24583079, Length=418, Percent_Identity=28.2296650717703, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI19921000, Length=418, Percent_Identity=28.2296650717703, Blast_Score=104, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 86095; Mature: 85964

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVETAMQPAASGESSSGRSPAPVIRKAAVLGAGTMGARIAAHLANAGLPVVLLDMATAE
CCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEHHCC
GARSKIAAQALEDLKKSKPAAFYDSAYAAHIIVGNFEDDMALLADCDWVIEAVTENLAIK
CHHHHHHHHHHHHHHHCCCCCHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
QSLLDKAVPHLKAGAILTTNTSGLPVAQIAAKLPADVRRRWFGTHFFNPPRYMRLLEIIP
HHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHCC
TPDADAAAIAAISHFADVLLGKEVVFARDTPNFIANRIGVFIMLEAVRLMQEEDLTIEEV
CCCCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DVLTGSVIGWPRTGTFRLADMVGIDVLAHVASNFAGSGTMPPFVKAMLERRWLGDKTRQG
HHHHCCEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHCC
FYKKEKDAEGKEIRLVLDWKTLEYVPAVRPKIASIEMAKNAEQLPARLQQLLAGDVRKDK
CCCCCCCCCCCEEEEEEECHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCHHHHH
AARFHWRLLTGLWNDAADCLPEIADDASSVDRAMRAGFNWEMGPFQLWDAAGVQEIVKRM
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHH
RAAGERVSPVAESVAHWYRAHSREVFDVVSGGYRPVKEAAGIGRIAKFRASNGVVRQNPG
HHCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCCHHHHCCCCHHHHHHCCCCCEECCCC
ASLVDLGDGVACLEMHSKKNAVGEDIVRLITETFSPGSDAVRNFEAFVVSNDSEHFSVGA
CCEEECCCCEEEHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHCCEEEEEECCCCHHHHHH
NLMQLLLSAQEEEWDDVDFAIRGFQRMTAAIKFCPRPVVVAPYSFCLGGGAEIAMHGAQR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHCCCCCEEECCHHH
QAHAELYMGLVETGVGVVPAGGGCKEMLLRSLDAGGAVHDAALRKNFETIAMAKVSTSAV
HHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHH
EARRMGLLLPADRITMNRERLLHDAKQSARELADGGYAAPVPRTDIPAPGENLLATLKLG
HHHHCCEECCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
VHMMRQGEFISDHDVKVANWVAYVLCGGPVTPGTLVSEQYLLDLEREAFLSLCGEKKTQE
HHHHHCCCCCCCCCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
RIAYTLKSGRPLRN
HHHHHHHCCCCCCC
>Mature Secondary Structure 
SVETAMQPAASGESSSGRSPAPVIRKAAVLGAGTMGARIAAHLANAGLPVVLLDMATAE
CCCHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEHHCC
GARSKIAAQALEDLKKSKPAAFYDSAYAAHIIVGNFEDDMALLADCDWVIEAVTENLAIK
CHHHHHHHHHHHHHHHCCCCCHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
QSLLDKAVPHLKAGAILTTNTSGLPVAQIAAKLPADVRRRWFGTHFFNPPRYMRLLEIIP
HHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHCC
TPDADAAAIAAISHFADVLLGKEVVFARDTPNFIANRIGVFIMLEAVRLMQEEDLTIEEV
CCCCCHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DVLTGSVIGWPRTGTFRLADMVGIDVLAHVASNFAGSGTMPPFVKAMLERRWLGDKTRQG
HHHHCCEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHCC
FYKKEKDAEGKEIRLVLDWKTLEYVPAVRPKIASIEMAKNAEQLPARLQQLLAGDVRKDK
CCCCCCCCCCCEEEEEEECHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHHCCHHHHH
AARFHWRLLTGLWNDAADCLPEIADDASSVDRAMRAGFNWEMGPFQLWDAAGVQEIVKRM
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHH
RAAGERVSPVAESVAHWYRAHSREVFDVVSGGYRPVKEAAGIGRIAKFRASNGVVRQNPG
HHCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCCHHHHCCCCHHHHHHCCCCCEECCCC
ASLVDLGDGVACLEMHSKKNAVGEDIVRLITETFSPGSDAVRNFEAFVVSNDSEHFSVGA
CCEEECCCCEEEHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHCCEEEEEECCCCHHHHHH
NLMQLLLSAQEEEWDDVDFAIRGFQRMTAAIKFCPRPVVVAPYSFCLGGGAEIAMHGAQR
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHCCCCCEEECCHHH
QAHAELYMGLVETGVGVVPAGGGCKEMLLRSLDAGGAVHDAALRKNFETIAMAKVSTSAV
HHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHH
EARRMGLLLPADRITMNRERLLHDAKQSARELADGGYAAPVPRTDIPAPGENLLATLKLG
HHHHCCEECCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
VHMMRQGEFISDHDVKVANWVAYVLCGGPVTPGTLVSEQYLLDLEREAFLSLCGEKKTQE
HHHHHCCCCCCCCCCHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHH
RIAYTLKSGRPLRN
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]