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The map label for this gene is kstR2 [H]

Identifier: 116624773

GI number: 116624773

Start: 7137324

End: 7137989

Strand: Reverse

Name: kstR2 [H]

Synonym: Acid_5697

Alternate gene names: 116624773

Gene position: 7137989-7137324 (Counterclockwise)

Preceding gene: 116624777

Following gene: 116624772

Centisome position: 71.63

GC content: 58.41

Gene sequence:

>666_bases
ATGTCTAAAGACGCCTCCGTAACGCCGTCTCCCCGCAAGGTCTTCGCTAGCAGGCGACGGGATCCAGCTACCAAGCGCGA
GGCGGTGTTGAAAACCGCGGCACAGCTTTTCCTGGAAAAGAGCTTTGGGCGGACGTCGATGAACGATGTCGCCGACCGGT
TAAATATCACCAAGCCCGCGCTCTACCACTATTTCGACAACAAGGAAGACATTTTGCTGGCCTGTTACCGGCTGGGCGTC
GGCCTCATTGAGGAAACGCTCAACGAGATCGCCGATCACTGTGGGAACGGACTCCAGAAGGTAGAGGCATTTATCCAGTC
CTACGCGATCGTAATGACGGTCAACTTCGGCCGCTGCGTGATGCGGCTGGATGAAGGCGACCTGACCGCCGAAGCGCGGG
CAGAGGTGAGGACGTACAAGCGGAAGATCGATCGCCGGCTGCGGAGCTTTCTACAGGAAGGAATCGACGATGGCTCCGTC
GCGCCATGCGATACGAAGATCGCGGCATTTGCCATCGCGGGGGCATTGAACTGGATCTGCATGTGGTACGAGCCCGATGG
GGCCCTGTCGCCGGAAGAGATTGCGGCGCAGTTCGCACGTACTTTGACGCAGGGTCTGGCGGCTAAAGGGCAATTCCCAA
AGAGGAGCAATTCGGATGAGCGTTGA

Upstream 100 bases:

>100_bases
GGGTGTCCGTGGCGCAAGTAATCCTCTTGCGTTTTTGCTTACCCGTGGGTAAGATATCAGCAGCTTCGCCTCATGTCAAT
AGGCGGATGTATCGTCTGTT

Downstream 100 bases:

>100_bases
AACAGCGATGCAACCGGCGGCGTCGGGAGAGTCTTCTTCCGGACGCTCGCCCGCACCGGTGATCCGCAAAGCGGCGGTGC
TGGGGGCCGGAACCATGGGA

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSKDASVTPSPRKVFASRRRDPATKREAVLKTAAQLFLEKSFGRTSMNDVADRLNITKPALYHYFDNKEDILLACYRLGV
GLIEETLNEIADHCGNGLQKVEAFIQSYAIVMTVNFGRCVMRLDEGDLTAEARAEVRTYKRKIDRRLRSFLQEGIDDGSV
APCDTKIAAFAIAGALNWICMWYEPDGALSPEEIAAQFARTLTQGLAAKGQFPKRSNSDER

Sequences:

>Translated_221_residues
MSKDASVTPSPRKVFASRRRDPATKREAVLKTAAQLFLEKSFGRTSMNDVADRLNITKPALYHYFDNKEDILLACYRLGV
GLIEETLNEIADHCGNGLQKVEAFIQSYAIVMTVNFGRCVMRLDEGDLTAEARAEVRTYKRKIDRRLRSFLQEGIDDGSV
APCDTKIAAFAIAGALNWICMWYEPDGALSPEEIAAQFARTLTQGLAAKGQFPKRSNSDER
>Mature_220_residues
SKDASVTPSPRKVFASRRRDPATKREAVLKTAAQLFLEKSFGRTSMNDVADRLNITKPALYHYFDNKEDILLACYRLGVG
LIEETLNEIADHCGNGLQKVEAFIQSYAIVMTVNFGRCVMRLDEGDLTAEARAEVRTYKRKIDRRLRSFLQEGIDDGSVA
PCDTKIAAFAIAGALNWICMWYEPDGALSPEEIAAQFARTLTQGLAAKGQFPKRSNSDER

Specific function: Controls the expression of a small regulon that may play a role in the utilization of cholesterol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24688; Mature: 24557

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDASVTPSPRKVFASRRRDPATKREAVLKTAAQLFLEKSFGRTSMNDVADRLNITKPA
CCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHH
LYHYFDNKEDILLACYRLGVGLIEETLNEIADHCGNGLQKVEAFIQSYAIVMTVNFGRCV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEECHHEE
MRLDEGDLTAEARAEVRTYKRKIDRRLRSFLQEGIDDGSVAPCDTKIAAFAIAGALNWIC
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHEEE
MWYEPDGALSPEEIAAQFARTLTQGLAAKGQFPKRSNSDER
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SKDASVTPSPRKVFASRRRDPATKREAVLKTAAQLFLEKSFGRTSMNDVADRLNITKPA
CCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHH
LYHYFDNKEDILLACYRLGVGLIEETLNEIADHCGNGLQKVEAFIQSYAIVMTVNFGRCV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEECHHEE
MRLDEGDLTAEARAEVRTYKRKIDRRLRSFLQEGIDDGSVAPCDTKIAAFAIAGALNWIC
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHEEE
MWYEPDGALSPEEIAAQFARTLTQGLAAKGQFPKRSNSDER
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA