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The map label for this gene is rcsC [C]

Identifier: 116624716

GI number: 116624716

Start: 7070804

End: 7071217

Strand: Reverse

Name: rcsC [C]

Synonym: Acid_5640

Alternate gene names: 116624716

Gene position: 7071217-7070804 (Counterclockwise)

Preceding gene: 116624719

Following gene: 116624713

Centisome position: 70.96

GC content: 61.84

Gene sequence:

>414_bases
ATGCCGCCCGAAACTATACTGATCGTTGACGACGACCCTATTTGCCTGGCCATCGCAAGTCTTGCGCTGCAAACGGCCGG
TTTTGCCACGCGGACCGCGGCCGATGGCATGGAGGCACTCGACCTTCTCAACCTCGAGCAACCTGCCCTGATACTGTCGG
ATATCCAAATGCCGCATATGGACGGCTTCGAACTGGCGCGGCGTACCCGTCAGATTCCGCGGTTTCGCGACATCCCGATG
GTGGCATTGACGGCCTTCGACGCCGCGGACACCGAACAACGTGCCCGTGATGCGGGCTTCACGGCTTACATGAAAAAGCC
GGTCCACGCCGCCAGCCTGGCAAACCGCCTTCGCCGGTTGCTGACAACGAGCCGCGACCGTGAGGGAGCGCTACCCTCAC
GCCACGGATCGTAA

Upstream 100 bases:

>100_bases
CCGAATATGGTACGTAAGCCGTACTAACGAAGGAAAACTTGTGTCGAGGTACTATCGTCAACGAGAATCGGAAAACTTTC
GATAGTGAATGCCTGGTACG

Downstream 100 bases:

>100_bases
CGCTCCCTCAGCTCACGGTCGCGGCTCGTTGACGCCGCATCTCCAGGCTGCAGGCACGGGCGGCGGCCCCAGCGGCATCA
CGCCATCGCGGTGCAGGCCC

Product: response regulator receiver protein

Products: NA

Alternate protein names: ORF131 [H]

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MPPETILIVDDDPICLAIASLALQTAGFATRTAADGMEALDLLNLEQPALILSDIQMPHMDGFELARRTRQIPRFRDIPM
VALTAFDAADTEQRARDAGFTAYMKKPVHAASLANRLRRLLTTSRDREGALPSRHGS

Sequences:

>Translated_137_residues
MPPETILIVDDDPICLAIASLALQTAGFATRTAADGMEALDLLNLEQPALILSDIQMPHMDGFELARRTRQIPRFRDIPM
VALTAFDAADTEQRARDAGFTAYMKKPVHAASLANRLRRLLTTSRDREGALPSRHGS
>Mature_136_residues
PPETILIVDDDPICLAIASLALQTAGFATRTAADGMEALDLLNLEQPALILSDIQMPHMDGFELARRTRQIPRFRDIPMV
ALTAFDAADTEQRARDAGFTAYMKKPVHAASLANRLRRLLTTSRDREGALPSRHGS

Specific function: Member Of The Two-Component Regulatory System rcsC/rcsB Involved In The Regulation Of The Expression Of Genes Involved In Colanic Acid Capsule Synthesis. rcsC Probably Functions As A Membrane-Associated Protein Kinase That Phosphorylates rcsB In Response

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=103, Percent_Identity=36.8932038834951, Blast_Score=77, Evalue=3e-16,
Organism=Escherichia coli, GI1788713, Length=120, Percent_Identity=31.6666666666667, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI48994928, Length=138, Percent_Identity=28.2608695652174, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI87082012, Length=113, Percent_Identity=30.9734513274336, Blast_Score=60, Evalue=6e-11,
Organism=Escherichia coli, GI1789149, Length=115, Percent_Identity=31.304347826087, Blast_Score=59, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 15056; Mature: 14924

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPETILIVDDDPICLAIASLALQTAGFATRTAADGMEALDLLNLEQPALILSDIQMPHM
CCCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCC
DGFELARRTRQIPRFRDIPMVALTAFDAADTEQRARDAGFTAYMKKPVHAASLANRLRRL
CHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHCCHHHHHHCCCHHHHHHHHHHHH
LTTSRDREGALPSRHGS
HHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PPETILIVDDDPICLAIASLALQTAGFATRTAADGMEALDLLNLEQPALILSDIQMPHM
CCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCC
DGFELARRTRQIPRFRDIPMVALTAFDAADTEQRARDAGFTAYMKKPVHAASLANRLRRL
CHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHCCHHHHHHCCCHHHHHHHHHHHH
LTTSRDREGALPSRHGS
HHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7860607 [H]