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The map label for this gene is nhaA1 [H]

Identifier: 116624599

GI number: 116624599

Start: 6928197

End: 6929219

Strand: Direct

Name: nhaA1 [H]

Synonym: Acid_5523

Alternate gene names: 116624599

Gene position: 6928197-6929219 (Clockwise)

Preceding gene: 116624596

Following gene: 116624612

Centisome position: 69.52

GC content: 60.51

Gene sequence:

>1023_bases
ATGCCATCAAGCCCGGTAGTATTCAGCGTGTTGGGTGCCGTTGCTGCCCTCGCAGTGACCGCCGTTCGCGCCCAGGAGGT
TGACAAGGCGGCAATGGTGAACGGCGCGCCGATCCTCGCCTCCGAGATCGACGCGAAGTTAGGGAACGACCTCGCACAGC
TTCAGCAGCAGATCTTCAATCTCCGCAAAAAGCAGCTCAACACCGTGATCGATCAGAAACTGCTGGAGGATGAGTCGGCG
AGACGCGGCGTCATGATCGCCGAACTCGTGCAGTCCGAGGTCACCTCGCATGTCACCCCCGCGACCTCCGCCGAAGCCGA
GAAATTCTTCAAGGAGAACAGTACGAAGCTGAAAGGTGATTTCAAGAGCCTCGAAGAGCAGATCAGGAATTTCCTGACGG
CTCAACGACTGCAGGCCAGGCAGCAGGAATTCCTGAAGTCGCTACGGACGGCCGCGAAAGTCGAAGTTTTCCTGGCGCCG
CCCCCTGTCTTCCGGTCGGAAGTATCTGTCGAGGGCGCCCCTTCCCGCGGCGGTGTGGCCGCTCCCGTCACCATCGTGGA
ATTCTCTGATTTCCACTGCCCTTTCTGCCGCAAGGCTCAATCGGTGCTCGACAATCTGCGCGCAAAGTACGGTGAAAAGA
TCAGATTCGTTTATCGCGATTTCCCTCTCGAGGGCCTCCATCCGCAGGCGCGGGTGGCCGCCGAGGCCTCGCGCTGTGCT
GCGGAACAGGGTAAGTTCTGGGAATTCCATGACCGCCTCTTCCACGGCGACCCCGACGCCTCGCAAGCCGCGTTGAGCCG
GATCGCGAAGGAGAGCGGGATGGACCTTACGGCTTTTGAAGCCTGCAGGACCTCCGGAAAGTACAAGAACTCGGTTCAAG
CGAGCGCTCAGGAGGGTGCGAGACTCGGCATTACCGGGACACCAACGTTCTTCGTCAACGGCCGCATGTTGGTCGGCTCG
CAGTCCCTCGACGAGTTTGTCAGCATCATCGACGAAGAGCTTGCCGCGGGCGCCGGGCGTTAG

Upstream 100 bases:

>100_bases
GCTAGAATAGCCCCCATCGCCGAAAACACGAGTTCTTCCGTGCGCGGCCGTTAACCCTGGTCGCCATCGGCGAAGTTTTG
GATCCGGCCTGGAGGAGTCA

Downstream 100 bases:

>100_bases
TTTGGCACCGCCCGCCGCGGGTTACTGGCAAGTGCATTTCGAAGCGGTCGCGGCGCAAAGTTGGGTAAGTTTAGCCTGTT
CGTTGCTACCCAACGGAACC

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 1 [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MPSSPVVFSVLGAVAALAVTAVRAQEVDKAAMVNGAPILASEIDAKLGNDLAQLQQQIFNLRKKQLNTVIDQKLLEDESA
RRGVMIAELVQSEVTSHVTPATSAEAEKFFKENSTKLKGDFKSLEEQIRNFLTAQRLQARQQEFLKSLRTAAKVEVFLAP
PPVFRSEVSVEGAPSRGGVAAPVTIVEFSDFHCPFCRKAQSVLDNLRAKYGEKIRFVYRDFPLEGLHPQARVAAEASRCA
AEQGKFWEFHDRLFHGDPDASQAALSRIAKESGMDLTAFEACRTSGKYKNSVQASAQEGARLGITGTPTFFVNGRMLVGS
QSLDEFVSIIDEELAAGAGR

Sequences:

>Translated_340_residues
MPSSPVVFSVLGAVAALAVTAVRAQEVDKAAMVNGAPILASEIDAKLGNDLAQLQQQIFNLRKKQLNTVIDQKLLEDESA
RRGVMIAELVQSEVTSHVTPATSAEAEKFFKENSTKLKGDFKSLEEQIRNFLTAQRLQARQQEFLKSLRTAAKVEVFLAP
PPVFRSEVSVEGAPSRGGVAAPVTIVEFSDFHCPFCRKAQSVLDNLRAKYGEKIRFVYRDFPLEGLHPQARVAAEASRCA
AEQGKFWEFHDRLFHGDPDASQAALSRIAKESGMDLTAFEACRTSGKYKNSVQASAQEGARLGITGTPTFFVNGRMLVGS
QSLDEFVSIIDEELAAGAGR
>Mature_339_residues
PSSPVVFSVLGAVAALAVTAVRAQEVDKAAMVNGAPILASEIDAKLGNDLAQLQQQIFNLRKKQLNTVIDQKLLEDESAR
RGVMIAELVQSEVTSHVTPATSAEAEKFFKENSTKLKGDFKSLEEQIRNFLTAQRLQARQQEFLKSLRTAAKVEVFLAPP
PVFRSEVSVEGAPSRGGVAAPVTIVEFSDFHCPFCRKAQSVLDNLRAKYGEKIRFVYRDFPLEGLHPQARVAAEASRCAA
EQGKFWEFHDRLFHGDPDASQAALSRIAKESGMDLTAFEACRTSGKYKNSVQASAQEGARLGITGTPTFFVNGRMLVGSQ
SLDEFVSIIDEELAAGAGR

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 37063; Mature: 36932

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSPVVFSVLGAVAALAVTAVRAQEVDKAAMVNGAPILASEIDAKLGNDLAQLQQQIFN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHH
LRKKQLNTVIDQKLLEDESARRGVMIAELVQSEVTSHVTPATSAEAEKFFKENSTKLKGD
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHH
FKSLEEQIRNFLTAQRLQARQQEFLKSLRTAAKVEVFLAPPPVFRSEVSVEGAPSRGGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHCCCCCCCCCCCCCCC
APVTIVEFSDFHCPFCRKAQSVLDNLRAKYGEKIRFVYRDFPLEGLHPQARVAAEASRCA
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEHEECCCCCCCCHHHHHHHHHHHHH
AEQGKFWEFHDRLFHGDPDASQAALSRIAKESGMDLTAFEACRTSGKYKNSVQASAQEGA
HHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCCC
RLGITGTPTFFVNGRMLVGSQSLDEFVSIIDEELAAGAGR
EECCCCCCEEEECCEEEECCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PSSPVVFSVLGAVAALAVTAVRAQEVDKAAMVNGAPILASEIDAKLGNDLAQLQQQIFN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHH
LRKKQLNTVIDQKLLEDESARRGVMIAELVQSEVTSHVTPATSAEAEKFFKENSTKLKGD
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHH
FKSLEEQIRNFLTAQRLQARQQEFLKSLRTAAKVEVFLAPPPVFRSEVSVEGAPSRGGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHCCCCCCCCCCCCCCC
APVTIVEFSDFHCPFCRKAQSVLDNLRAKYGEKIRFVYRDFPLEGLHPQARVAAEASRCA
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEHEECCCCCCCCHHHHHHHHHHHHH
AEQGKFWEFHDRLFHGDPDASQAALSRIAKESGMDLTAFEACRTSGKYKNSVQASAQEGA
HHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCCC
RLGITGTPTFFVNGRMLVGSQSLDEFVSIIDEELAAGAGR
EECCCCCCEEEECCEEEECCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA