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The map label for this gene is glpD2 [H]

Identifier: 116624596

GI number: 116624596

Start: 6921786

End: 6923315

Strand: Direct

Name: glpD2 [H]

Synonym: Acid_5520

Alternate gene names: 116624596

Gene position: 6921786-6923315 (Clockwise)

Preceding gene: 116624595

Following gene: 116624599

Centisome position: 69.46

GC content: 66.6

Gene sequence:

>1530_bases
ATGTACCTTCGGCTCCGCGAGCACAACGGCCCGTGGGACATGATCGTCATCGGAGGCGGCGCTACCGGCGCCGGCGTCGC
CGTGGACGCATCCACCCGCGGCTATAGCGTCCTCCTCCTCGAGCAGAGCGATTTCGGTAAGGGCACCTCCAGCCGCAGTA
CCAAGCTCGTGCACGGCGGCGTCCGTTATCTGGAACAGGGCAATCTCTCGCTCGTTATGGAGGCCCTCAAGGAGCGCGGA
CTGCTGCTCCGCAACGCGCCCCACCTGGTCCGCAACCTCGGCTTCGTCGTCCCCAATTACGACTGGTGGCAGGCGCCCTT
CTACGGAGTCGGCCTCAAGGTCTACGACCTGCTGGCTGGGAAATACGGCTTCGGCAGTTCGCGCATTCTCTCGCGCGAGG
AGACCCTGGCGCGCCTCCCCACCATCCGCGCCGAAGATCTGCGCGGCGGCGTCATCTACTTCGACGGCCAGTTTGACGAC
GCGCGCCTCCTCATTCATCTGCTTGCCACTGCCTTCGACCACGGCGCAAGTCTCTTCAATCACACGCGCGTGGTCGCTGC
CGCCTGCGATGGCGTCCGCGTGCGCGACGAAGAAACCGGCGAGGAGTTCGATGCCGCCGCGCGCGTCGTGATCAATGCCA
CCGGCGCCTTCAGCGATTCCGTCCGCCGCATGGCCGACCCCACGGCCGCCCCAATCATCGCTCCCAGCCAGGGCATCCAC
CTGGTCTTCGACCGCTCGTTTCTCCCCGGCGACAACGCCATCATGGTGCCGCACACCAGCGATGGCCGCGTCATGTTCGC
CATTCCCTGGCACGGCCATACCGTGGTCGGCACTACCGACACCCCGGTGCCGCAAGCCTCGCTCGAACCAGTCGCCATGG
AGCAGGAGATCGACTTCATCCTGCAAACGGCCGCGCTCTATCTGGCCAAGCCGCCCTTCCGCGCCGACGTCCTCAGCGTC
TTCGCCGGCATCCGTCCGCTCGTCAAACAGGGTGACGCCGGACGTACCGCGTCGCTATCCCGCGACCACACCATCATCAT
CGAAGACTCCGGCATCGTCACTATCGCCGGCGGCAAGTGGACCACCTATCGCCGCATGGCCGAGGATTGCGTCAATCAGG
CTGCCACCCTCGGCGGCCTCGAAGAACGCCCCTGCGTCACCGCCGACCTGCCCGTCCACGGCAGCCATCGCGCGGCCGAC
GCCTTCGGGGCGCTCTCGGTCTATGGCTCCGACGCCCCCGCCGTGCGCGAGTTGTCCGGCGACCGTCTTCACCCCGCATT
GCCGTATACCAGTGGTGAAGTTCTCTGGGCCGTCCGCCACGAAATGGCGCTCACCGTGGAAGACGTGCTCGCCCGCCGCA
CACGCGCGCTCTTCCTCAACGCCCGCGCCGCCGTTCAAATGGCTCCCCAGGTCGCCGCTCTGATGGCCCGCGAACTGGGC
CGCGACCAGCAGTGGATCGCCACCCAACTCGAGTCTTTTCGCGCCGTCGCACAGCATTATCTGATCGGGCCCGCTAGTCT
TCCGGACTAG

Upstream 100 bases:

>100_bases
CCATCGAAGTCTTCGGCCCCCTGCAACCCGGCGACATGATCGTCAAACGTGCCACCGACGAAATCCGCGAAGGAACGAAA
CTGAAGTGACCCGGCCTGAA

Downstream 100 bases:

>100_bases
CCGAAATTCTCGCGCACAAGGTCAATCGCTGCGTGCCGCAATGCATTGCCGCGCACCTGCTTCCTCGCCGGCCGCGAGTT
TCCGCGCCGGAGAATTCGCC

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MYLRLREHNGPWDMIVIGGGATGAGVAVDASTRGYSVLLLEQSDFGKGTSSRSTKLVHGGVRYLEQGNLSLVMEALKERG
LLLRNAPHLVRNLGFVVPNYDWWQAPFYGVGLKVYDLLAGKYGFGSSRILSREETLARLPTIRAEDLRGGVIYFDGQFDD
ARLLIHLLATAFDHGASLFNHTRVVAAACDGVRVRDEETGEEFDAAARVVINATGAFSDSVRRMADPTAAPIIAPSQGIH
LVFDRSFLPGDNAIMVPHTSDGRVMFAIPWHGHTVVGTTDTPVPQASLEPVAMEQEIDFILQTAALYLAKPPFRADVLSV
FAGIRPLVKQGDAGRTASLSRDHTIIIEDSGIVTIAGGKWTTYRRMAEDCVNQAATLGGLEERPCVTADLPVHGSHRAAD
AFGALSVYGSDAPAVRELSGDRLHPALPYTSGEVLWAVRHEMALTVEDVLARRTRALFLNARAAVQMAPQVAALMARELG
RDQQWIATQLESFRAVAQHYLIGPASLPD

Sequences:

>Translated_509_residues
MYLRLREHNGPWDMIVIGGGATGAGVAVDASTRGYSVLLLEQSDFGKGTSSRSTKLVHGGVRYLEQGNLSLVMEALKERG
LLLRNAPHLVRNLGFVVPNYDWWQAPFYGVGLKVYDLLAGKYGFGSSRILSREETLARLPTIRAEDLRGGVIYFDGQFDD
ARLLIHLLATAFDHGASLFNHTRVVAAACDGVRVRDEETGEEFDAAARVVINATGAFSDSVRRMADPTAAPIIAPSQGIH
LVFDRSFLPGDNAIMVPHTSDGRVMFAIPWHGHTVVGTTDTPVPQASLEPVAMEQEIDFILQTAALYLAKPPFRADVLSV
FAGIRPLVKQGDAGRTASLSRDHTIIIEDSGIVTIAGGKWTTYRRMAEDCVNQAATLGGLEERPCVTADLPVHGSHRAAD
AFGALSVYGSDAPAVRELSGDRLHPALPYTSGEVLWAVRHEMALTVEDVLARRTRALFLNARAAVQMAPQVAALMARELG
RDQQWIATQLESFRAVAQHYLIGPASLPD
>Mature_509_residues
MYLRLREHNGPWDMIVIGGGATGAGVAVDASTRGYSVLLLEQSDFGKGTSSRSTKLVHGGVRYLEQGNLSLVMEALKERG
LLLRNAPHLVRNLGFVVPNYDWWQAPFYGVGLKVYDLLAGKYGFGSSRILSREETLARLPTIRAEDLRGGVIYFDGQFDD
ARLLIHLLATAFDHGASLFNHTRVVAAACDGVRVRDEETGEEFDAAARVVINATGAFSDSVRRMADPTAAPIIAPSQGIH
LVFDRSFLPGDNAIMVPHTSDGRVMFAIPWHGHTVVGTTDTPVPQASLEPVAMEQEIDFILQTAALYLAKPPFRADVLSV
FAGIRPLVKQGDAGRTASLSRDHTIIIEDSGIVTIAGGKWTTYRRMAEDCVNQAATLGGLEERPCVTADLPVHGSHRAAD
AFGALSVYGSDAPAVRELSGDRLHPALPYTSGEVLWAVRHEMALTVEDVLARRTRALFLNARAAVQMAPQVAALMARELG
RDQQWIATQLESFRAVAQHYLIGPASLPD

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=546, Percent_Identity=41.025641025641, Blast_Score=389, Evalue=1e-108,
Organism=Homo sapiens, GI285002231, Length=546, Percent_Identity=41.025641025641, Blast_Score=389, Evalue=1e-108,
Organism=Escherichia coli, GI2367226, Length=478, Percent_Identity=28.2426778242678, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1788574, Length=470, Percent_Identity=29.1489361702128, Blast_Score=109, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17509253, Length=527, Percent_Identity=43.2637571157495, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI115534726, Length=511, Percent_Identity=40.7045009784736, Blast_Score=349, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6322036, Length=554, Percent_Identity=33.5740072202166, Blast_Score=310, Evalue=3e-85,
Organism=Drosophila melanogaster, GI161077125, Length=517, Percent_Identity=40.8123791102514, Blast_Score=356, Evalue=2e-98,
Organism=Drosophila melanogaster, GI24653942, Length=517, Percent_Identity=40.8123791102514, Blast_Score=356, Evalue=2e-98,
Organism=Drosophila melanogaster, GI24653944, Length=517, Percent_Identity=40.8123791102514, Blast_Score=356, Evalue=2e-98,
Organism=Drosophila melanogaster, GI20130025, Length=517, Percent_Identity=40.8123791102514, Blast_Score=356, Evalue=2e-98,
Organism=Drosophila melanogaster, GI24586295, Length=530, Percent_Identity=35.6603773584906, Blast_Score=287, Evalue=1e-77,
Organism=Drosophila melanogaster, GI19921278, Length=523, Percent_Identity=31.3575525812619, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI45550977, Length=409, Percent_Identity=29.5843520782396, Blast_Score=184, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 55181; Mature: 55181

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLRLREHNGPWDMIVIGGGATGAGVAVDASTRGYSVLLLEQSDFGKGTSSRSTKLVHGG
CEEEEEECCCCEEEEEECCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCEEEECH
VRYLEQGNLSLVMEALKERGLLLRNAPHLVRNLGFVVPNYDWWQAPFYGVGLKVYDLLAG
HHHHHCCCHHHHHHHHHHCCCEEECCHHHHHHCCEECCCCCCCCCCEEECCHHHHHHHHC
KYGFGSSRILSREETLARLPTIRAEDLRGGVIYFDGQFDDARLLIHLLATAFDHGASLFN
CCCCCCCHHCCHHHHHHHCCCCCHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
HTRVVAAACDGVRVRDEETGEEFDAAARVVINATGAFSDSVRRMADPTAAPIIAPSQGIH
HHEEEEEECCCCEECCCCCCHHHHHEEEEEEEECCCCHHHHHHHCCCCCCCEECCCCCEE
LVFDRSFLPGDNAIMVPHTSDGRVMFAIPWHGHTVVGTTDTPVPQASLEPVAMEQEIDFI
EEEECCCCCCCCEEEEEECCCCEEEEEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHH
LQTAALYLAKPPFRADVLSVFAGIRPLVKQGDAGRTASLSRDHTIIIEDSGIVTIAGGKW
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCEEEEECCCC
TTYRRMAEDCVNQAATLGGLEERPCVTADLPVHGSHRAADAFGALSVYGSDAPAVRELSG
HHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHCEEEEECCCCCHHHHCCC
DRLHPALPYTSGEVLWAVRHEMALTVEDVLARRTRALFLNARAAVQMAPQVAALMARELG
CCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHC
RDQQWIATQLESFRAVAQHYLIGPASLPD
CCHHHHHHHHHHHHHHHHHHEECCCCCCC
>Mature Secondary Structure
MYLRLREHNGPWDMIVIGGGATGAGVAVDASTRGYSVLLLEQSDFGKGTSSRSTKLVHGG
CEEEEEECCCCEEEEEECCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCEEEECH
VRYLEQGNLSLVMEALKERGLLLRNAPHLVRNLGFVVPNYDWWQAPFYGVGLKVYDLLAG
HHHHHCCCHHHHHHHHHHCCCEEECCHHHHHHCCEECCCCCCCCCCEEECCHHHHHHHHC
KYGFGSSRILSREETLARLPTIRAEDLRGGVIYFDGQFDDARLLIHLLATAFDHGASLFN
CCCCCCCHHCCHHHHHHHCCCCCHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
HTRVVAAACDGVRVRDEETGEEFDAAARVVINATGAFSDSVRRMADPTAAPIIAPSQGIH
HHEEEEEECCCCEECCCCCCHHHHHEEEEEEEECCCCHHHHHHHCCCCCCCEECCCCCEE
LVFDRSFLPGDNAIMVPHTSDGRVMFAIPWHGHTVVGTTDTPVPQASLEPVAMEQEIDFI
EEEECCCCCCCCEEEEEECCCCEEEEEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHH
LQTAALYLAKPPFRADVLSVFAGIRPLVKQGDAGRTASLSRDHTIIIEDSGIVTIAGGKW
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCEEEEECCCC
TTYRRMAEDCVNQAATLGGLEERPCVTADLPVHGSHRAADAFGALSVYGSDAPAVRELSG
HHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHCEEEEECCCCCHHHHCCC
DRLHPALPYTSGEVLWAVRHEMALTVEDVLARRTRALFLNARAAVQMAPQVAALMARELG
CCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHC
RDQQWIATQLESFRAVAQHYLIGPASLPD
CCHHHHHHHHHHHHHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]