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The map label for this gene is rna [C]

Identifier: 116624582

GI number: 116624582

Start: 6900673

End: 6901311

Strand: Reverse

Name: rna [C]

Synonym: Acid_5506

Alternate gene names: 116624582

Gene position: 6901311-6900673 (Counterclockwise)

Preceding gene: 116624585

Following gene: 116624581

Centisome position: 69.25

GC content: 61.82

Gene sequence:

>639_bases
ATGAGGGTCGCCATTCTGATTGCCGCGCTGCTTTTCTGCGGAACGCTTTCGGGCGCGCGAAAGAAGAAGGCGGCGGCGCC
GCAAAGCTTCGACTATTACCTGCTGACGCTTTCCTGGGCTCCGGATTTCTGCGCACAGACCAACTCCAAGAACCCGGCCG
AATGCGGTCCGGGGCGGAAGGTCGGTTTCGTGGTGCATGGGCTTTGGCCACAGGGTGAGACCGGCCGCGGGCCGATGAAT
TGCGGAGGCAGTCCGGTCTCGCAGAGCGTGGTGGAGACAATGTTGAATTATTTCCCGACGGCGAGCCTGATTCAGCACGA
ATGGCAGACACACGGCACCTGCACGGGTCTGAGCGCGGCGGACTATTTCGCGCTGGTACGCAAAGCTCGCGACTCGGTGA
AAATTCCCAGTGGATTTCAGGCGCCTACGCAGACCGTAACGGAGAGTCCGGCGCAGATCGAGGCAGCGTTCGCCGCCGCG
AGCCCGAACTTCCCAAAGCAGGCATTTCGCACCTCCTGCACCGCCGGCGCCCTACAAGACGTACGAATCTGCTTTAACAA
AGACCTCTCGCCGCGCGCCTGCAGCACGAGTGCCGGCGAGTGTCCCGCACCCGCGATCCAGGTTCTGCCGGTAAAATAA

Upstream 100 bases:

>100_bases
CACGTTGGGGGCCGCGCGGATTTCGGGGCAGGGAAGGCGCTTTTGTGTCTCACGGGGGACGCTGTGTGCGGCCGGGACAC
GCTCCTGCTAACATCCGGGT

Downstream 100 bases:

>100_bases
AACTTACGGATCTTAAATCTTTTTTACACGCCCGGCCGTTGTAAGGTCGAAAGCTGCAATTCAAATGGCGGCGGTGATAA
TAATCCGGCAGAGCTCAGCC

Product: ribonuclease T2

Products: 3'- Phosphomononucleotides; 3'-Phosphooligonucleotides [C]

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MRVAILIAALLFCGTLSGARKKKAAAPQSFDYYLLTLSWAPDFCAQTNSKNPAECGPGRKVGFVVHGLWPQGETGRGPMN
CGGSPVSQSVVETMLNYFPTASLIQHEWQTHGTCTGLSAADYFALVRKARDSVKIPSGFQAPTQTVTESPAQIEAAFAAA
SPNFPKQAFRTSCTAGALQDVRICFNKDLSPRACSTSAGECPAPAIQVLPVK

Sequences:

>Translated_212_residues
MRVAILIAALLFCGTLSGARKKKAAAPQSFDYYLLTLSWAPDFCAQTNSKNPAECGPGRKVGFVVHGLWPQGETGRGPMN
CGGSPVSQSVVETMLNYFPTASLIQHEWQTHGTCTGLSAADYFALVRKARDSVKIPSGFQAPTQTVTESPAQIEAAFAAA
SPNFPKQAFRTSCTAGALQDVRICFNKDLSPRACSTSAGECPAPAIQVLPVK
>Mature_212_residues
MRVAILIAALLFCGTLSGARKKKAAAPQSFDYYLLTLSWAPDFCAQTNSKNPAECGPGRKVGFVVHGLWPQGETGRGPMN
CGGSPVSQSVVETMLNYFPTASLIQHEWQTHGTCTGLSAADYFALVRKARDSVKIPSGFQAPTQTVTESPAQIEAAFAAA
SPNFPKQAFRTSCTAGALQDVRICFNKDLSPRACSTSAGECPAPAIQVLPVK

Specific function: One of the few RNases that cleave the phosphodiester bond between any two nucleotide. Shows a preference for adenylic acid [H]

COG id: COG3719

COG function: function code J; Ribonuclease I

Gene ontology:

Cell location: Periplasm. Cytoplasm. Note=An RNase I-like form (periplasmic) and RNase I*-like form (cytoplasmic) appear to be isoforms apparently encoded by the same gene. The cytoplasmic form is less active towards natural polymer RNA [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase T2 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17562468, Length=194, Percent_Identity=28.3505154639175, Blast_Score=77, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001568
- InterPro:   IPR018188 [H]

Pfam domain/function: PF00445 Ribonuclease_T2 [H]

EC number: 3.1.27.6 [C]

Molecular weight: Translated: 22486; Mature: 22486

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS00530 RNASE_T2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAILIAALLFCGTLSGARKKKAAAPQSFDYYLLTLSWAPDFCAQTNSKNPAECGPGRK
CHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEEECCCHHHHHCCCCCCCCCCCCCE
VGFVVHGLWPQGETGRGPMNCGGSPVSQSVVETMLNYFPTASLIQHEWQTHGTCTGLSAA
EEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHH
DYFALVRKARDSVKIPSGFQAPTQTVTESPAQIEAAFAAASPNFPKQAFRTSCTAGALQD
HHHHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCHHHHHHHCCHHHHHH
VRICFNKDLSPRACSTSAGECPAPAIQVLPVK
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MRVAILIAALLFCGTLSGARKKKAAAPQSFDYYLLTLSWAPDFCAQTNSKNPAECGPGRK
CHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEEEEECCCHHHHHCCCCCCCCCCCCCE
VGFVVHGLWPQGETGRGPMNCGGSPVSQSVVETMLNYFPTASLIQHEWQTHGTCTGLSAA
EEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHH
DYFALVRKARDSVKIPSGFQAPTQTVTESPAQIEAAFAAASPNFPKQAFRTSCTAGALQD
HHHHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCHHHHHHHCCHHHHHH
VRICFNKDLSPRACSTSAGECPAPAIQVLPVK
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Nucleotides [C]

Specific reaction: Endonucleolytic Cleavage With 2',3'-Cyclic Phosphate Intermediates. [C]

General reaction: Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685334 [H]