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The map label for this gene is glsA [H]

Identifier: 116624486

GI number: 116624486

Start: 6775945

End: 6777012

Strand: Reverse

Name: glsA [H]

Synonym: Acid_5408

Alternate gene names: 116624486

Gene position: 6777012-6775945 (Counterclockwise)

Preceding gene: 116624490

Following gene: 116624485

Centisome position: 68.0

GC content: 57.4

Gene sequence:

>1068_bases
ATGTCTATCCAAACGCGGACGACCAAAACTGTTCTCGCAGGAATACTGATCGCCACCGGCGTCCTTTCCATCGTGCTCTC
CGCCCAATCACGCGGTAGTGCGAACCGGAGCGCCGTTGCACCCCGGCAGGAATTCGTCAAACGGGCAGTTGATGAAGCAT
ATGCAAAATTCCGCAGCGACACCACCGGCAAGAATGCCGACTACATCCCGTACCTGGCCCAGGTAGACTCGAAACTCTTC
GGGGTATCGGTGGTCACCACGGATAACGAGAGTTACTCGGTCGGCGACACGTCCTATGCGTTTTCCATTCAATCGATCTC
GAAAGTCTTCACGCTTGCCCTTGCGATGAAGGAGCTGGGCGCCGCGAAGGTCTTCGAACGCATTGGATCGGAGCCTACGG
GTAGAGCGTTCAACTCAGTGATCGCGGTTGTGGACATGCCCAGTCACACTGGGAATCCGCTGGTGAATGCGGGGGCGATC
GCGACCACAAGTCTCATTTCCGGAGCCGGCGCCGCTGAGAAATGGAGCAAGATTCTCGAGTTCTACGGAAAGGCGGCGGG
AGAGAAGCTCTCCTTAATCGACGAGGTCTACAAGTCGGAAGCAGCCACAAATCAGGGGAATCGTGCCCTTGCGGCGCTGC
TGGTCAAATACGAACGCATCTATTCCGATCCGCTCGAAGCGGTAGACATCTACACCAAGGCCTGTTCCGTCGGCGCGAAT
ACCAAACAACTTGCCCAGATGGGTGCCACCCTGGCCAACAATGGGCGCAATCCGGTAACCGGTGAGCAGGTCATCAGGGA
GGAAGACATCCCACACATCCTGTCCGCGATGACAATGGCGGGCTTGTATGACGGGTCGGGCGGTTGGGCCTGGCACGTGG
GCCTGCCGGCAAAGAGCGGCGTAGGAGGCGCGATTCTGGCGATCGCTCCCGGTAAAGGTGCGATTGCCGTGTTCGCCCCG
CGGCTGGACGAAGCCGGTAATAGCGTGAAAGCTCAAAAAGTAATCACATACGTGGCGGATAAGTTGGATTACAATCTCTT
CTCCCCCAAATCCGTAGGGTTGAAGTAG

Upstream 100 bases:

>100_bases
TTTCAATCGCGTCGCCGCGCAGACCACTCCGATGGGGTCGTTCATTCAAATTCACACTCGACCGGCACGAGCTCGTCGAG
TTAGGCAACAGGAGGAAGAA

Downstream 100 bases:

>100_bases
CCGCGCCTTAACCGGAAGGCCCATGATCTCTCGCCGTGAAAGATCGCGCAGTTCGATGGAGCTTCTTCGCGGATTGATTT
TGGCCGCCTTGCTCGCTGCA

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSIQTRTTKTVLAGILIATGVLSIVLSAQSRGSANRSAVAPRQEFVKRAVDEAYAKFRSDTTGKNADYIPYLAQVDSKLF
GVSVVTTDNESYSVGDTSYAFSIQSISKVFTLALAMKELGAAKVFERIGSEPTGRAFNSVIAVVDMPSHTGNPLVNAGAI
ATTSLISGAGAAEKWSKILEFYGKAAGEKLSLIDEVYKSEAATNQGNRALAALLVKYERIYSDPLEAVDIYTKACSVGAN
TKQLAQMGATLANNGRNPVTGEQVIREEDIPHILSAMTMAGLYDGSGGWAWHVGLPAKSGVGGAILAIAPGKGAIAVFAP
RLDEAGNSVKAQKVITYVADKLDYNLFSPKSVGLK

Sequences:

>Translated_355_residues
MSIQTRTTKTVLAGILIATGVLSIVLSAQSRGSANRSAVAPRQEFVKRAVDEAYAKFRSDTTGKNADYIPYLAQVDSKLF
GVSVVTTDNESYSVGDTSYAFSIQSISKVFTLALAMKELGAAKVFERIGSEPTGRAFNSVIAVVDMPSHTGNPLVNAGAI
ATTSLISGAGAAEKWSKILEFYGKAAGEKLSLIDEVYKSEAATNQGNRALAALLVKYERIYSDPLEAVDIYTKACSVGAN
TKQLAQMGATLANNGRNPVTGEQVIREEDIPHILSAMTMAGLYDGSGGWAWHVGLPAKSGVGGAILAIAPGKGAIAVFAP
RLDEAGNSVKAQKVITYVADKLDYNLFSPKSVGLK
>Mature_354_residues
SIQTRTTKTVLAGILIATGVLSIVLSAQSRGSANRSAVAPRQEFVKRAVDEAYAKFRSDTTGKNADYIPYLAQVDSKLFG
VSVVTTDNESYSVGDTSYAFSIQSISKVFTLALAMKELGAAKVFERIGSEPTGRAFNSVIAVVDMPSHTGNPLVNAGAIA
TTSLISGAGAAEKWSKILEFYGKAAGEKLSLIDEVYKSEAATNQGNRALAALLVKYERIYSDPLEAVDIYTKACSVGANT
KQLAQMGATLANNGRNPVTGEQVIREEDIPHILSAMTMAGLYDGSGGWAWHVGLPAKSGVGGAILAIAPGKGAIAVFAPR
LDEAGNSVKAQKVITYVADKLDYNLFSPKSVGLK

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=336, Percent_Identity=38.3928571428571, Blast_Score=208, Evalue=6e-54,
Organism=Homo sapiens, GI20336214, Length=323, Percent_Identity=37.1517027863777, Blast_Score=188, Evalue=6e-48,
Organism=Escherichia coli, GI1786693, Length=302, Percent_Identity=50.9933774834437, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI1787804, Length=285, Percent_Identity=34.3859649122807, Blast_Score=177, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI17532727, Length=274, Percent_Identity=39.4160583941606, Blast_Score=189, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI193204073, Length=325, Percent_Identity=34.4615384615385, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI193204075, Length=328, Percent_Identity=34.1463414634146, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17507019, Length=315, Percent_Identity=33.968253968254, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI281363241, Length=326, Percent_Identity=33.4355828220859, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24653162, Length=326, Percent_Identity=33.4355828220859, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI281363239, Length=326, Percent_Identity=33.4355828220859, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24653158, Length=326, Percent_Identity=33.4355828220859, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24653164, Length=326, Percent_Identity=33.4355828220859, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24653156, Length=326, Percent_Identity=33.4355828220859, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI116008307, Length=326, Percent_Identity=33.4355828220859, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24653166, Length=326, Percent_Identity=33.4355828220859, Blast_Score=188, Evalue=4e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 37351; Mature: 37220

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQTRTTKTVLAGILIATGVLSIVLSAQSRGSANRSAVAPRQEFVKRAVDEAYAKFRSD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
TTGKNADYIPYLAQVDSKLFGVSVVTTDNESYSVGDTSYAFSIQSISKVFTLALAMKELG
CCCCCCCCCHHHHHHCCHHEEEEEEEECCCCEECCCCHHEEEHHHHHHHHHHHHHHHHHH
AAKVFERIGSEPTGRAFNSVIAVVDMPSHTGNPLVNAGAIATTSLISGAGAAEKWSKILE
HHHHHHHHCCCCCCHHHHHEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHH
FYGKAAGEKLSLIDEVYKSEAATNQGNRALAALLVKYERIYSDPLEAVDIYTKACSVGAN
HHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
TKQLAQMGATLANNGRNPVTGEQVIREEDIPHILSAMTMAGLYDGSGGWAWHVGLPAKSG
HHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCEECCCCEEEEECCCCCCC
VGGAILAIAPGKGAIAVFAPRLDEAGNSVKAQKVITYVADKLDYNLFSPKSVGLK
CCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SIQTRTTKTVLAGILIATGVLSIVLSAQSRGSANRSAVAPRQEFVKRAVDEAYAKFRSD
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
TTGKNADYIPYLAQVDSKLFGVSVVTTDNESYSVGDTSYAFSIQSISKVFTLALAMKELG
CCCCCCCCCHHHHHHCCHHEEEEEEEECCCCEECCCCHHEEEHHHHHHHHHHHHHHHHHH
AAKVFERIGSEPTGRAFNSVIAVVDMPSHTGNPLVNAGAIATTSLISGAGAAEKWSKILE
HHHHHHHHCCCCCCHHHHHEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHH
FYGKAAGEKLSLIDEVYKSEAATNQGNRALAALLVKYERIYSDPLEAVDIYTKACSVGAN
HHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
TKQLAQMGATLANNGRNPVTGEQVIREEDIPHILSAMTMAGLYDGSGGWAWHVGLPAKSG
HHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCEECCCCEEEEECCCCCCC
VGGAILAIAPGKGAIAVFAPRLDEAGNSVKAQKVITYVADKLDYNLFSPKSVGLK
CCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA