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The map label for this gene is cheB2 [H]

Identifier: 116624452

GI number: 116624452

Start: 6733419

End: 6734477

Strand: Direct

Name: cheB2 [H]

Synonym: Acid_5374

Alternate gene names: 116624452

Gene position: 6733419-6734477 (Clockwise)

Preceding gene: 116624451

Following gene: 116624454

Centisome position: 67.57

GC content: 66.76

Gene sequence:

>1059_bases
ATGCTCTCCAACCGCAAGATCCGCATCCTGATCGTCGACGATTCCGCCATCGTCCGCAAGATCCTCACCGAGGCCCTCTC
AGGAGAGCCCGATATGGAGGTCGTGGGGACGGCGCCCGATCCCTTCGTCGCGCGCGACAAGATTCTCACCTTGCGTCCCG
ACGTCCTCACGCTCGATATCGAGATGCCGCGCATGGACGGCCTTACTTTCCTCCGCAAGCTCATGCACTTCCACCCGCTG
CCCACGGTGGTCATCAGCAGCCTCGCCCAGGAATCCTGCAGCGCCGCCGTCCAGGCACTGGAATCCGGAGCCGTGGAAGT
ACTCGCCAAACCCGGCGGCCCCTATTCGGTCGGCGAACTCAGCCATTCCCTGGCCTCGAAAGTCCGCGCCGCCGCCTCCT
CCCGCATCCGCCGTTCCGAACCGCCCCCCGCGCCGCATCCCGCCGCCCCCAATACGCCGACGCCCGGCCCGCCCACCCGA
TTGACCTCCCGCTCACCATCGGGAACCATCTTCGCCATTGGAGCCAGCACCGGTGGCACCGAAGCTATCGCCAGCGTACT
CACCCGGCTGCCCGAGGCCTCTCCCGCCATCGTGATCACACAACACATCCCACCGGTCTTCTCCAAAGCATTCGCCAATC
GCCTGAACCAGATCTGCGCCCTCGAAGTCCGCGAGGCCGTGGATGGCGATGTCGTCCGCCCAGGCCTCGCCCTGATTGCC
CCCGGCGATTTCCACATGCTGCTGCGCCACTCCGGCGGCCAATACTCCGTGAGCGTCAAAGCCGGACCGCGCGTCTGCTA
CCAGCGCCCTTCGGTGGACGTCCTCTTCTCCTCCGTCGCCGAAGCCGCCGGCAAACGCGCCGTGGGCGTCCTGCTCACCG
GGATGGGTAGCGATGGCGCCCAAGGCCTCCTCCAAATGCGCCGCGCAGGAGCCCGCACCATCGCCCAGGACGAAGCCACC
TGTGTAGTCTATGGCATGCCTCGCGAAGCCGTCGAACTCGGCGCCGCCGCGCAGGTTCTCCCGCTCAACTCCGTCGCCCA
AGCCATGCTCGCGGGATAA

Upstream 100 bases:

>100_bases
GCACGCTCGAGCAGCCCGCCGGCCCCCTCCCCCGAAACACCTGCACGGTGGAAACCGGCAGCGGCCTGCTCACAGCCGGA
ATCGATATGGAAACCAGGAC

Downstream 100 bases:

>100_bases
CCGGACCTCACCCGAAGTTGACGCAGCCCTATTCCGAACGCTACAGTAGAAGAGTTCGCCCGCTTTTTGGTCAGCACGTC
CCCATCGTCTAGCCTGGCCT

Product: response regulator receiver modulated CheB methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MLSNRKIRILIVDDSAIVRKILTEALSGEPDMEVVGTAPDPFVARDKILTLRPDVLTLDIEMPRMDGLTFLRKLMHFHPL
PTVVISSLAQESCSAAVQALESGAVEVLAKPGGPYSVGELSHSLASKVRAAASSRIRRSEPPPAPHPAAPNTPTPGPPTR
LTSRSPSGTIFAIGASTGGTEAIASVLTRLPEASPAIVITQHIPPVFSKAFANRLNQICALEVREAVDGDVVRPGLALIA
PGDFHMLLRHSGGQYSVSVKAGPRVCYQRPSVDVLFSSVAEAAGKRAVGVLLTGMGSDGAQGLLQMRRAGARTIAQDEAT
CVVYGMPREAVELGAAAQVLPLNSVAQAMLAG

Sequences:

>Translated_352_residues
MLSNRKIRILIVDDSAIVRKILTEALSGEPDMEVVGTAPDPFVARDKILTLRPDVLTLDIEMPRMDGLTFLRKLMHFHPL
PTVVISSLAQESCSAAVQALESGAVEVLAKPGGPYSVGELSHSLASKVRAAASSRIRRSEPPPAPHPAAPNTPTPGPPTR
LTSRSPSGTIFAIGASTGGTEAIASVLTRLPEASPAIVITQHIPPVFSKAFANRLNQICALEVREAVDGDVVRPGLALIA
PGDFHMLLRHSGGQYSVSVKAGPRVCYQRPSVDVLFSSVAEAAGKRAVGVLLTGMGSDGAQGLLQMRRAGARTIAQDEAT
CVVYGMPREAVELGAAAQVLPLNSVAQAMLAG
>Mature_352_residues
MLSNRKIRILIVDDSAIVRKILTEALSGEPDMEVVGTAPDPFVARDKILTLRPDVLTLDIEMPRMDGLTFLRKLMHFHPL
PTVVISSLAQESCSAAVQALESGAVEVLAKPGGPYSVGELSHSLASKVRAAASSRIRRSEPPPAPHPAAPNTPTPGPPTR
LTSRSPSGTIFAIGASTGGTEAIASVLTRLPEASPAIVITQHIPPVFSKAFANRLNQICALEVREAVDGDVVRPGLALIA
PGDFHMLLRHSGGQYSVSVKAGPRVCYQRPSVDVLFSSVAEAAGKRAVGVLLTGMGSDGAQGLLQMRRAGARTIAQDEAT
CVVYGMPREAVELGAAAQVLPLNSVAQAMLAG

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=348, Percent_Identity=53.448275862069, Blast_Score=353, Evalue=1e-98,
Organism=Escherichia coli, GI1786911, Length=139, Percent_Identity=33.8129496402878, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 36859; Mature: 36859

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSNRKIRILIVDDSAIVRKILTEALSGEPDMEVVGTAPDPFVARDKILTLRPDVLTLDI
CCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEECCCEEEEEE
EMPRMDGLTFLRKLMHFHPLPTVVISSLAQESCSAAVQALESGAVEVLAKPGGPYSVGEL
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHH
SHSLASKVRAAASSRIRRSEPPPAPHPAAPNTPTPGPPTRLTSRSPSGTIFAIGASTGGT
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCH
EAIASVLTRLPEASPAIVITQHIPPVFSKAFANRLNQICALEVREAVDGDVVRPGLALIA
HHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
PGDFHMLLRHSGGQYSVSVKAGPRVCYQRPSVDVLFSSVAEAAGKRAVGVLLTGMGSDGA
CCCEEEEEECCCCEEEEEEECCCCCEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHH
QGLLQMRRAGARTIAQDEATCVVYGMPREAVELGAAAQVLPLNSVAQAMLAG
HHHHHHHHHCCHHCCCCCCEEEEEECCHHHHHHCCCCEEECHHHHHHHHHCC
>Mature Secondary Structure
MLSNRKIRILIVDDSAIVRKILTEALSGEPDMEVVGTAPDPFVARDKILTLRPDVLTLDI
CCCCCEEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEECCCEEEEEE
EMPRMDGLTFLRKLMHFHPLPTVVISSLAQESCSAAVQALESGAVEVLAKPGGPYSVGEL
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHH
SHSLASKVRAAASSRIRRSEPPPAPHPAAPNTPTPGPPTRLTSRSPSGTIFAIGASTGGT
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCH
EAIASVLTRLPEASPAIVITQHIPPVFSKAFANRLNQICALEVREAVDGDVVRPGLALIA
HHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
PGDFHMLLRHSGGQYSVSVKAGPRVCYQRPSVDVLFSSVAEAAGKRAVGVLLTGMGSDGA
CCCEEEEEECCCCEEEEEEECCCCCEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCHH
QGLLQMRRAGARTIAQDEATCVVYGMPREAVELGAAAQVLPLNSVAQAMLAG
HHHHHHHHHCCHHCCCCCCEEEEEECCHHHHHHCCCCEEECHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA