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The map label for this gene is yfbQ [H]

Identifier: 116624362

GI number: 116624362

Start: 6622777

End: 6623943

Strand: Direct

Name: yfbQ [H]

Synonym: Acid_5283

Alternate gene names: 116624362

Gene position: 6622777-6623943 (Clockwise)

Preceding gene: 116624361

Following gene: 116624365

Centisome position: 66.46

GC content: 67.1

Gene sequence:

>1167_bases
ATGTTCTCCTCCCGCTTCCATTGGGACCCGCGCCCTAATCGACTCACGCTCGCCCTCGCCGCCCGCCGCGCGGCGGGGGC
GCCCATCCTCGACCTCACCGAATCCAACCCCACGCACGCCGGCCTGGACTATCCGCCCGCGATCGTCGCCTCCTTCGCCG
AACCGCGCATGTTGGCCTACGAACCCGCGCCCGCCGGAGTCCCCACTGCCCGCGAAGCCGTGAGCGCCTACTACGCAGCA
CGCGGCCACCGCGTCGATCCGTCCCGCCTACTCCTCACGGCCAGCACCAGCGAGGCCTACTGCTATCTCTTCAAGCTCCT
CGCCGACCCCGGCGACGAGGTCCTCGTGCCCAGCCCCTCCTACCCCCTCTTCGAGTTTCTCGCCGGTATGGAATCCCTCG
CGGTGCGCCCCTACCCGCTCGAGTATCACGGCGCATGGCGCATCGACCTCGCCGCGCTCGAGGCGTCCCTCACGCCGCGC
ACTCGCGCTATAGTCCTGGTGAATCCGAACAACCCGACCGGTTCTTACGTCAAGCGCGCCGAGCTTCACGCGCTCACGGC
TCTCTGCGCCGCCCGGCGCATCGCCCTGATCTCCGACGAAGTCTTCGCCGATTACGCGCTGACCGACGACCACCAACGCG
TCGCAACCCTCGCCGGCGTAGAGGAGTGCCTGGCGTTTTCGATGAGCGGCCTCTCCAAAGTCGCCGGACTGCCGCAGATG
AAGCTTGGCTGGATTGTCGCCGCCGGGCCCGATGCTTTGCGTTGCGAAGCGCTTGAGAAACTCGAGTGGATCGCCGACAC
CTACCTCTCCGTCAGCACTCCCGTGCAATGCGCCGCTCCGGCGTTGCTTGCCGCCGGTGAGGCCGTGCAGCGGCAGATTC
GCGAACGCACCGCGGCCAACCTCGCCTTTGCCCGCGCCACGCTGGCGCACTCCGCAGCCAATATCCTGGCGGTGGAAGGC
GGCTGGTACATCACGCTGCAAGTCCCGCGCATTCACAGTGAAGAGGAGTGGACCCTGCGATTATTGGAACAGGATGGTGT
GCTGGTGCAGCCCGGCTTCTTCTATGACTTCGAATCCGAGGCGTACCTGGTGGTCAGCCTTCTGACCGCGCCTGATATCT
TCCGCGAAGGCCTGCCCCGCATCGCCGCCGCGGTGGCCTGCGCCTGA

Upstream 100 bases:

>100_bases
GCGTCGGAGCGTTAAACGTGTTGCTGATGGTCGATGGGCAAGCGTCCAACACGATCGCGGTGACTCTCCAGTAGCCCGCC
CCGCTACAATCGGTGAGGAC

Downstream 100 bases:

>100_bases
CGCCTACGCCAGTTGCTTCTGCTGCGGCCGCGGCGCCTGGGCAATCGAAACCACGCCCTTGTCGAAAACCGTCATGTCCT
GAACCATTCGGCCGACATCG

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MFSSRFHWDPRPNRLTLALAARRAAGAPILDLTESNPTHAGLDYPPAIVASFAEPRMLAYEPAPAGVPTAREAVSAYYAA
RGHRVDPSRLLLTASTSEAYCYLFKLLADPGDEVLVPSPSYPLFEFLAGMESLAVRPYPLEYHGAWRIDLAALEASLTPR
TRAIVLVNPNNPTGSYVKRAELHALTALCAARRIALISDEVFADYALTDDHQRVATLAGVEECLAFSMSGLSKVAGLPQM
KLGWIVAAGPDALRCEALEKLEWIADTYLSVSTPVQCAAPALLAAGEAVQRQIRERTAANLAFARATLAHSAANILAVEG
GWYITLQVPRIHSEEEWTLRLLEQDGVLVQPGFFYDFESEAYLVVSLLTAPDIFREGLPRIAAAVACA

Sequences:

>Translated_388_residues
MFSSRFHWDPRPNRLTLALAARRAAGAPILDLTESNPTHAGLDYPPAIVASFAEPRMLAYEPAPAGVPTAREAVSAYYAA
RGHRVDPSRLLLTASTSEAYCYLFKLLADPGDEVLVPSPSYPLFEFLAGMESLAVRPYPLEYHGAWRIDLAALEASLTPR
TRAIVLVNPNNPTGSYVKRAELHALTALCAARRIALISDEVFADYALTDDHQRVATLAGVEECLAFSMSGLSKVAGLPQM
KLGWIVAAGPDALRCEALEKLEWIADTYLSVSTPVQCAAPALLAAGEAVQRQIRERTAANLAFARATLAHSAANILAVEG
GWYITLQVPRIHSEEEWTLRLLEQDGVLVQPGFFYDFESEAYLVVSLLTAPDIFREGLPRIAAAVACA
>Mature_388_residues
MFSSRFHWDPRPNRLTLALAARRAAGAPILDLTESNPTHAGLDYPPAIVASFAEPRMLAYEPAPAGVPTAREAVSAYYAA
RGHRVDPSRLLLTASTSEAYCYLFKLLADPGDEVLVPSPSYPLFEFLAGMESLAVRPYPLEYHGAWRIDLAALEASLTPR
TRAIVLVNPNNPTGSYVKRAELHALTALCAARRIALISDEVFADYALTDDHQRVATLAGVEECLAFSMSGLSKVAGLPQM
KLGWIVAAGPDALRCEALEKLEWIADTYLSVSTPVQCAAPALLAAGEAVQRQIRERTAANLAFARATLAHSAANILAVEG
GWYITLQVPRIHSEEEWTLRLLEQDGVLVQPGFFYDFESEAYLVVSLLTAPDIFREGLPRIAAAVACA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=326, Percent_Identity=25.4601226993865, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI95147551, Length=232, Percent_Identity=28.448275862069, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI169881279, Length=232, Percent_Identity=28.448275862069, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI56713256, Length=229, Percent_Identity=28.82096069869, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI56713254, Length=227, Percent_Identity=28.6343612334802, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI4885351, Length=152, Percent_Identity=34.2105263157895, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1788627, Length=361, Percent_Identity=28.5318559556787, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1788722, Length=378, Percent_Identity=25.1322751322751, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787710, Length=290, Percent_Identity=25.1724137931034, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786816, Length=265, Percent_Identity=27.5471698113208, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=365, Percent_Identity=23.013698630137, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=210, Percent_Identity=30.952380952381, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71994476, Length=210, Percent_Identity=30.952380952381, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17567369, Length=225, Percent_Identity=28, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=210, Percent_Identity=24.2857142857143, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320317, Length=153, Percent_Identity=28.7581699346405, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI18859735, Length=405, Percent_Identity=24.6913580246914, Blast_Score=104, Evalue=8e-23,
Organism=Drosophila melanogaster, GI28573069, Length=262, Percent_Identity=25.5725190839695, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24646114, Length=262, Percent_Identity=25.5725190839695, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28573067, Length=262, Percent_Identity=25.5725190839695, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28573065, Length=262, Percent_Identity=25.5725190839695, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42088; Mature: 42088

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSSRFHWDPRPNRLTLALAARRAAGAPILDLTESNPTHAGLDYPPAIVASFAEPRMLAY
CCCCCCCCCCCCCEEEEEEEEHHHCCCCEEEECCCCCCCCCCCCCHHHHHHCCCCCEEEE
EPAPAGVPTAREAVSAYYAARGHRVDPSRLLLTASTSEAYCYLFKLLADPGDEVLVPSPS
CCCCCCCCHHHHHHHHHHHHCCCCCCHHHEEEEECCCCHHHHHHHHHHCCCCCEEECCCC
YPLFEFLAGMESLAVRPYPLEYHGAWRIDLAALEASLTPRTRAIVLVNPNNPTGSYVKRA
CHHHHHHCCHHHHCCCCCCCCCCCCEEEEEEEHHCCCCCCEEEEEEECCCCCCCHHHHHH
ELHALTALCAARRIALISDEVFADYALTDDHQRVATLAGVEECLAFSMSGLSKVAGLPQM
HHHHHHHHHHHHHHHEECHHHHHCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
KLGWIVAAGPDALRCEALEKLEWIADTYLSVSTPVQCAAPALLAAGEAVQRQIRERTAAN
EEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
LAFARATLAHSAANILAVEGGWYITLQVPRIHSEEEWTLRLLEQDGVLVQPGFFYDFESE
HHHHHHHHHHCCCEEEEEECCEEEEEEECCCCCCCCCEEEEEECCCEEECCCEEEECCCC
AYLVVSLLTAPDIFREGLPRIAAAVACA
CEEEEEEHHCHHHHHHCHHHHHHHHHCC
>Mature Secondary Structure
MFSSRFHWDPRPNRLTLALAARRAAGAPILDLTESNPTHAGLDYPPAIVASFAEPRMLAY
CCCCCCCCCCCCCEEEEEEEEHHHCCCCEEEECCCCCCCCCCCCCHHHHHHCCCCCEEEE
EPAPAGVPTAREAVSAYYAARGHRVDPSRLLLTASTSEAYCYLFKLLADPGDEVLVPSPS
CCCCCCCCHHHHHHHHHHHHCCCCCCHHHEEEEECCCCHHHHHHHHHHCCCCCEEECCCC
YPLFEFLAGMESLAVRPYPLEYHGAWRIDLAALEASLTPRTRAIVLVNPNNPTGSYVKRA
CHHHHHHCCHHHHCCCCCCCCCCCCEEEEEEEHHCCCCCCEEEEEEECCCCCCCHHHHHH
ELHALTALCAARRIALISDEVFADYALTDDHQRVATLAGVEECLAFSMSGLSKVAGLPQM
HHHHHHHHHHHHHHHEECHHHHHCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
KLGWIVAAGPDALRCEALEKLEWIADTYLSVSTPVQCAAPALLAAGEAVQRQIRERTAAN
EEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
LAFARATLAHSAANILAVEGGWYITLQVPRIHSEEEWTLRLLEQDGVLVQPGFFYDFESE
HHHHHHHHHHCCCEEEEEECCEEEEEEECCCCCCCCCEEEEEECCCEEECCCEEEECCCC
AYLVVSLLTAPDIFREGLPRIAAAVACA
CEEEEEEHHCHHHHHHCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]