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The map label for this gene is cdd [H]

Identifier: 116624316

GI number: 116624316

Start: 6568751

End: 6569146

Strand: Direct

Name: cdd [H]

Synonym: Acid_5234

Alternate gene names: 116624316

Gene position: 6568751-6569146 (Clockwise)

Preceding gene: 116624315

Following gene: 116624317

Centisome position: 65.91

GC content: 60.61

Gene sequence:

>396_bases
ATGACCTCCTCGGGCGACCAGTTGGTGAACGCGGCGCTGGCAGTACGGCTGAATGCCTTCGCGCCGTACTCGAAATTCCT
GGTGGGCGCCGCGATTGAAGATGTCGATGGGCGGGTGCACACCGGCTGCAATGTGGAGAACGCGACCTACGGGCTGACGC
TATGCGCGGAGCGGGTCGCGGTTTTCAAGGCGATCAGCGAAGGCGCGCGGAAATTCCGGCGTGTCGCGGTGGCCGCCGAT
ACGGAAACGCTTACGCCGCCGTGCGGAGCCTGCCGGCAGATTCTCTGGGAGTTTTGCGGAGATATCGAGCTGGTGCTGGC
AAACCTCAGCGGCAAAACCGAAACCTATCATTTGAAAGAGCTGTTCCCCAAACCCTTCGATGTATCGTATCTGTAG

Upstream 100 bases:

>100_bases
TGCCGCAGAAGATCAATCACGAAGAGGTGCTGGAGACCGGCGCGATGGTGCGCGACACGCTGGTGCGTTTCCTGAAGGCC
CTGCTGCCAAGGTTGGACGC

Downstream 100 bases:

>100_bases
CTTTTTCCTCTTCGCGCTGGCACTGGCCGCGCAAGCGCCAAGTCAATCGGCGGACCTGATCTGGAGTGCGCGCTATGTAA
TCACGATGGACGCGCAGCGG

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 131; Mature: 130

Protein sequence:

>131_residues
MTSSGDQLVNAALAVRLNAFAPYSKFLVGAAIEDVDGRVHTGCNVENATYGLTLCAERVAVFKAISEGARKFRRVAVAAD
TETLTPPCGACRQILWEFCGDIELVLANLSGKTETYHLKELFPKPFDVSYL

Sequences:

>Translated_131_residues
MTSSGDQLVNAALAVRLNAFAPYSKFLVGAAIEDVDGRVHTGCNVENATYGLTLCAERVAVFKAISEGARKFRRVAVAAD
TETLTPPCGACRQILWEFCGDIELVLANLSGKTETYHLKELFPKPFDVSYL
>Mature_130_residues
TSSGDQLVNAALAVRLNAFAPYSKFLVGAAIEDVDGRVHTGCNVENATYGLTLCAERVAVFKAISEGARKFRRVAVAADT
ETLTPPCGACRQILWEFCGDIELVLANLSGKTETYHLKELFPKPFDVSYL

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=122, Percent_Identity=40.9836065573771, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17551074, Length=130, Percent_Identity=43.0769230769231, Blast_Score=101, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17540514, Length=104, Percent_Identity=49.0384615384615, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323274, Length=130, Percent_Identity=35.3846153846154, Blast_Score=77, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24582741, Length=132, Percent_Identity=42.4242424242424, Blast_Score=97, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920920, Length=111, Percent_Identity=47.7477477477478, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24582744, Length=106, Percent_Identity=47.1698113207547, Blast_Score=92, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14216; Mature: 14085

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSGDQLVNAALAVRLNAFAPYSKFLVGAAIEDVDGRVHTGCNVENATYGLTLCAERVA
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHH
VFKAISEGARKFRRVAVAADTETLTPPCGACRQILWEFCGDIELVLANLSGKTETYHLKE
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEHHH
LFPKPFDVSYL
HCCCCCCCCCC
>Mature Secondary Structure 
TSSGDQLVNAALAVRLNAFAPYSKFLVGAAIEDVDGRVHTGCNVENATYGLTLCAERVA
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHH
VFKAISEGARKFRRVAVAADTETLTPPCGACRQILWEFCGDIELVLANLSGKTETYHLKE
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEHHH
LFPKPFDVSYL
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2526291; 8969508; 9384377 [H]