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The map label for this gene is alkR [H]

Identifier: 116624279

GI number: 116624279

Start: 6524386

End: 6525369

Strand: Direct

Name: alkR [H]

Synonym: Acid_5197

Alternate gene names: 116624279

Gene position: 6524386-6525369 (Clockwise)

Preceding gene: 116624270

Following gene: 116624283

Centisome position: 65.47

GC content: 61.59

Gene sequence:

>984_bases
ATGGATGCTTTCTCCGAAATTCTGAGCGGCGTCAAACTGAACGGCGCGGTCTTCTTTAGCGCCGAATTTTCGGCTCCCTG
GGGCTTTTCGTCGCCCGCGTCGAAACAGATGGCAGCCACGCTCGGCCTCGGCGCGTCGCATGTTGTCCTGTACCATTTCG
TCGTCGAAGGCGGTGCCCTCGTCGAACTGCCCGAGCGACAGTCCGTAGAGCTCAAGCCCGGGGATATCGTCATCTTTCCG
CATGGCGATCCCCACCACATGAGCAGTGGCGCGGAGGCGACCCGGCCCTTCCCGAACTACGGGATTATGTCCAAAATCAA
GGCGCGCGATTTAAGCCCCCTGCACGCCGGCGGCGGTGGTGAAACCTCGCGCTTCGTCTGCGGATATATGACTTGCGATC
CTTACGTCAGCCGCCCGATCCTAAGCGGCTTGCCTGCCGTATTCAAGGTCAATATCCGAACCGATCGCGCCGGGCACTGG
CTCGAGAACTCCATCCTGCACTTGGTGGAAGAAGCAGCCTCGGGACGGGTCGGCAGCGAAGCCATGTTGGCCAAACTCTC
CGAAGCCCTCTTCGTTGACACCTTGCGGCGCTACGTAGCCGGCCTGCCCGATCAGCAAGTAGGATGGCTCGCGGGAGCGC
GCGACCCCATCGTCGGCAAGAGCCTCGGCTTGCTCCATAGCCGCGTTTCCCATCCGTGGACCATCGCCGATCTCGCGGAC
GAAGTCGGTATTTCACGCTCTGCTCTCGTCGAACGCTTTACCCGCTACCTTTCCGAGCCCCCCATGGCCTACCTGACCCG
TTGGAGACTGACCCTGGCAGCGCGTTCGCTCGAAAAAACCTCCCGCGGCGTCGCCGAAATCGCCGCCGATGTCGGCTACG
AATCCGAAGCTGCCTTCAATCGAGCCTTCAAGCGCGAGTTTGGCTCGCCTCCCGGCCGCTACCGCACCCATCACAAATCA
TCGCCCCAAGAAAAGACAGCCTGA

Upstream 100 bases:

>100_bases
AACCATGCCCGAGCGTCTCCATATTTTGCTCAAGCGGCTTAGGGGAGCCGATTGCTTTGCATAACGGCCACGAATCTTTG
CAGACCGTCCGGAGGCTTGA

Downstream 100 bases:

>100_bases
CCGATCCGCCCGCCTCGTATTTCACCCCGCCGACGAGCCGCGACCGTAAGGCAAAGGAGCGCAACGAAATCCCGCCCGCG
ACGCGAACGTTTCCGGACGG

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MDAFSEILSGVKLNGAVFFSAEFSAPWGFSSPASKQMAATLGLGASHVVLYHFVVEGGALVELPERQSVELKPGDIVIFP
HGDPHHMSSGAEATRPFPNYGIMSKIKARDLSPLHAGGGGETSRFVCGYMTCDPYVSRPILSGLPAVFKVNIRTDRAGHW
LENSILHLVEEAASGRVGSEAMLAKLSEALFVDTLRRYVAGLPDQQVGWLAGARDPIVGKSLGLLHSRVSHPWTIADLAD
EVGISRSALVERFTRYLSEPPMAYLTRWRLTLAARSLEKTSRGVAEIAADVGYESEAAFNRAFKREFGSPPGRYRTHHKS
SPQEKTA

Sequences:

>Translated_327_residues
MDAFSEILSGVKLNGAVFFSAEFSAPWGFSSPASKQMAATLGLGASHVVLYHFVVEGGALVELPERQSVELKPGDIVIFP
HGDPHHMSSGAEATRPFPNYGIMSKIKARDLSPLHAGGGGETSRFVCGYMTCDPYVSRPILSGLPAVFKVNIRTDRAGHW
LENSILHLVEEAASGRVGSEAMLAKLSEALFVDTLRRYVAGLPDQQVGWLAGARDPIVGKSLGLLHSRVSHPWTIADLAD
EVGISRSALVERFTRYLSEPPMAYLTRWRLTLAARSLEKTSRGVAEIAADVGYESEAAFNRAFKREFGSPPGRYRTHHKS
SPQEKTA
>Mature_327_residues
MDAFSEILSGVKLNGAVFFSAEFSAPWGFSSPASKQMAATLGLGASHVVLYHFVVEGGALVELPERQSVELKPGDIVIFP
HGDPHHMSSGAEATRPFPNYGIMSKIKARDLSPLHAGGGGETSRFVCGYMTCDPYVSRPILSGLPAVFKVNIRTDRAGHW
LENSILHLVEEAASGRVGSEAMLAKLSEALFVDTLRRYVAGLPDQQVGWLAGARDPIVGKSLGLLHSRVSHPWTIADLAD
EVGISRSALVERFTRYLSEPPMAYLTRWRLTLAARSLEKTSRGVAEIAADVGYESEAAFNRAFKREFGSPPGRYRTHHKS
SPQEKTA

Specific function: This protein activates the expression of the alkane 1- monooxygenase AlkM [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786496, Length=316, Percent_Identity=25.6329113924051, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 35518; Mature: 35518

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAFSEILSGVKLNGAVFFSAEFSAPWGFSSPASKQMAATLGLGASHVVLYHFVVEGGAL
CCHHHHHHCCCEECCEEEEEEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCE
VELPERQSVELKPGDIVIFPHGDPHHMSSGAEATRPFPNYGIMSKIKARDLSPLHAGGGG
EECCCCCCEEECCCCEEEECCCCCHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCC
ETSRFVCGYMTCDPYVSRPILSGLPAVFKVNIRTDRAGHWLENSILHLVEEAASGRVGSE
CCCCEEEEEECCCHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHH
AMLAKLSEALFVDTLRRYVAGLPDQQVGWLAGARDPIVGKSLGLLHSRVSHPWTIADLAD
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCEEHHHHHH
EVGISRSALVERFTRYLSEPPMAYLTRWRLTLAARSLEKTSRGVAEIAADVGYESEAAFN
HHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RAFKREFGSPPGRYRTHHKSSPQEKTA
HHHHHHHCCCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure
MDAFSEILSGVKLNGAVFFSAEFSAPWGFSSPASKQMAATLGLGASHVVLYHFVVEGGAL
CCHHHHHHCCCEECCEEEEEEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCE
VELPERQSVELKPGDIVIFPHGDPHHMSSGAEATRPFPNYGIMSKIKARDLSPLHAGGGG
EECCCCCCEEECCCCEEEECCCCCHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCC
ETSRFVCGYMTCDPYVSRPILSGLPAVFKVNIRTDRAGHWLENSILHLVEEAASGRVGSE
CCCCEEEEEECCCHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHH
AMLAKLSEALFVDTLRRYVAGLPDQQVGWLAGARDPIVGKSLGLLHSRVSHPWTIADLAD
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCEEHHHHHH
EVGISRSALVERFTRYLSEPPMAYLTRWRLTLAARSLEKTSRGVAEIAADVGYESEAAFN
HHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RAFKREFGSPPGRYRTHHKSSPQEKTA
HHHHHHHCCCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9546151 [H]