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The map label for this gene is apbE [H]

Identifier: 116624283

GI number: 116624283

Start: 6527895

End: 6528848

Strand: Direct

Name: apbE [H]

Synonym: Acid_5201

Alternate gene names: 116624283

Gene position: 6527895-6528848 (Clockwise)

Preceding gene: 116624279

Following gene: 116624284

Centisome position: 65.5

GC content: 60.06

Gene sequence:

>954_bases
TTGTTTCTGTTGGCGGCTTCGGCGGCCTTCGGGCAGCAGGAACTCCTGCGGCTCGAAAAGAGCGCCGACGCCATGGGTTC
AACCTATTCCATAGCCCTGTACGGGTACGACCGGGTCAAAATGGAGGCGGCGGCGGATGCGGCCTTCGATGAGGTCCGGC
GGCTCGATGACCTGCTTTCGAATTACAAGCCGGCGAGCGAGTGGAGCGAGGTGAACCGGTACGCGGCGGAGCGCCCGGTG
AAGGTGTCGCCGGAGTTGTTCCGCTTGCTCTCGGCATGCCTCGAATACAGCCGGGAAAGTGAAGGCGCGTTCGATATCTC
GGTGGGTCCGCTGATGAAGGTTTGGGGGTTCTATAAAGGCTCCGGCCACCTCCCCCACAAGCCCGAAATTGCGGCTGCGC
TGGCCAAGGTCGGCTACCAGCATGTCCATCTGGATGCGGCGGCCCAGACGGTGCGGTTTGACCGTCCGGGTGTGGAATTA
GACCCAGGTGGGATCGGCAAAGGCTACGCCGTCGATCGCATGGTGGATGTTTTGAGACGGAACGGCGTGGTGACAGCTTT
GGTCGCCGGGTCCGGAAGCAGTATTTATGGTATGGGGGCGCCGCCGGATGAGCCCAAAGGCTGGCCCGTGAAGATCAAGG
ACCCCTGGGATAACCGCAAGACGCTGTCGGAGGTCTTCCTGAAAGACTCTTCGATGTCGACATCCGGAAGTTATGAGAAG
TTTTTCCGGGCGGAGGGCAAGATTTATGCCCATATTATGGACCCGCGGACCGGTTATCCGGCGCAGGGGAGCAGTTCGGT
TTCGGTGATTGCGCCGCGGACTATCGATAGCGAGGCGTGGGCCAAACCTTATTTCGTGAATGGCCGCCAGTGGGCGGTGA
AGCATCGGCCAAAGGACTTTCGAGTGTTCTTTTGCGAAGACAGGATGGATAAGCCATGCGCGTGGCTCCAATGA

Upstream 100 bases:

>100_bases
GCACGCCATCTTTTCATCGGTGGGTTACCGGGCGGTATGAAAGCATAGTGCCGTTGAAAATAAACGTTTTAGATGGCCGC
AAGTCAAAACTGTGATTGTT

Downstream 100 bases:

>100_bases
CAAGCCGTTTCTTAGATGCATGCCGGAGAAGGCCGACCGACGTCAGGCCGGTCTGGTTCATGCGTCAAGCCGGGCGATAC
ATGAAGCAGTACCGGCAGAT

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MFLLAASAAFGQQELLRLEKSADAMGSTYSIALYGYDRVKMEAAADAAFDEVRRLDDLLSNYKPASEWSEVNRYAAERPV
KVSPELFRLLSACLEYSRESEGAFDISVGPLMKVWGFYKGSGHLPHKPEIAAALAKVGYQHVHLDAAAQTVRFDRPGVEL
DPGGIGKGYAVDRMVDVLRRNGVVTALVAGSGSSIYGMGAPPDEPKGWPVKIKDPWDNRKTLSEVFLKDSSMSTSGSYEK
FFRAEGKIYAHIMDPRTGYPAQGSSSVSVIAPRTIDSEAWAKPYFVNGRQWAVKHRPKDFRVFFCEDRMDKPCAWLQ

Sequences:

>Translated_317_residues
MFLLAASAAFGQQELLRLEKSADAMGSTYSIALYGYDRVKMEAAADAAFDEVRRLDDLLSNYKPASEWSEVNRYAAERPV
KVSPELFRLLSACLEYSRESEGAFDISVGPLMKVWGFYKGSGHLPHKPEIAAALAKVGYQHVHLDAAAQTVRFDRPGVEL
DPGGIGKGYAVDRMVDVLRRNGVVTALVAGSGSSIYGMGAPPDEPKGWPVKIKDPWDNRKTLSEVFLKDSSMSTSGSYEK
FFRAEGKIYAHIMDPRTGYPAQGSSSVSVIAPRTIDSEAWAKPYFVNGRQWAVKHRPKDFRVFFCEDRMDKPCAWLQ
>Mature_317_residues
MFLLAASAAFGQQELLRLEKSADAMGSTYSIALYGYDRVKMEAAADAAFDEVRRLDDLLSNYKPASEWSEVNRYAAERPV
KVSPELFRLLSACLEYSRESEGAFDISVGPLMKVWGFYKGSGHLPHKPEIAAALAKVGYQHVHLDAAAQTVRFDRPGVEL
DPGGIGKGYAVDRMVDVLRRNGVVTALVAGSGSSIYGMGAPPDEPKGWPVKIKDPWDNRKTLSEVFLKDSSMSTSGSYEK
FFRAEGKIYAHIMDPRTGYPAQGSSSVSVIAPRTIDSEAWAKPYFVNGRQWAVKHRPKDFRVFFCEDRMDKPCAWLQ

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=304, Percent_Identity=28.2894736842105, Blast_Score=125, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 35163; Mature: 35163

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLLAASAAFGQQELLRLEKSADAMGSTYSIALYGYDRVKMEAAADAAFDEVRRLDDLLS
CEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHH
NYKPASEWSEVNRYAAERPVKVSPELFRLLSACLEYSRESEGAFDISVGPLMKVWGFYKG
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHEECC
SGHLPHKPEIAAALAKVGYQHVHLDAAAQTVRFDRPGVELDPGGIGKGYAVDRMVDVLRR
CCCCCCCHHHHHHHHHCCHHEEEEHHHHHHEEECCCCCEECCCCCCCCHHHHHHHHHHHH
NGVVTALVAGSGSSIYGMGAPPDEPKGWPVKIKDPWDNRKTLSEVFLKDSSMSTSGSYEK
CCEEEEEEECCCCEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCHHH
FFRAEGKIYAHIMDPRTGYPAQGSSSVSVIAPRTIDSEAWAKPYFVNGRQWAVKHRPKDF
HHHCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCHHHCCCCEEECCCEEEEEECCCCE
RVFFCEDRMDKPCAWLQ
EEEEECCCCCCCCCCCC
>Mature Secondary Structure
MFLLAASAAFGQQELLRLEKSADAMGSTYSIALYGYDRVKMEAAADAAFDEVRRLDDLLS
CEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCEEHHHHHHHHHHHHHHHHHHHH
NYKPASEWSEVNRYAAERPVKVSPELFRLLSACLEYSRESEGAFDISVGPLMKVWGFYKG
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHEECC
SGHLPHKPEIAAALAKVGYQHVHLDAAAQTVRFDRPGVELDPGGIGKGYAVDRMVDVLRR
CCCCCCCHHHHHHHHHCCHHEEEEHHHHHHEEECCCCCEECCCCCCCCHHHHHHHHHHHH
NGVVTALVAGSGSSIYGMGAPPDEPKGWPVKIKDPWDNRKTLSEVFLKDSSMSTSGSYEK
CCEEEEEEECCCCEEEECCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCHHH
FFRAEGKIYAHIMDPRTGYPAQGSSSVSVIAPRTIDSEAWAKPYFVNGRQWAVKHRPKDF
HHHCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCHHHCCCCEEECCCEEEEEECCCCE
RVFFCEDRMDKPCAWLQ
EEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]