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The map label for this gene is dgoD [H]

Identifier: 116624136

GI number: 116624136

Start: 6381580

End: 6382818

Strand: Direct

Name: dgoD [H]

Synonym: Acid_5052

Alternate gene names: 116624136

Gene position: 6381580-6382818 (Clockwise)

Preceding gene: 116624130

Following gene: 116624137

Centisome position: 64.04

GC content: 65.05

Gene sequence:

>1239_bases
ATGAACCGGAGAACCCTCCTACGCTCCGCGGCCGCCGCCGCCGGACTCTCCCTCGCGGGACGCGACGCCGCCCGCGCCGC
CATTCCCAAAATGAAGGTCACCCGTGTCCGCGTCTACTCTCCCCCCAATCCCAACCCCCTCTTCAACCAGAGCGACATGG
TCGTCACCGTCGAAACCGACGCCGGTATCACCGGCATCGGTGAAGGCGGCTCGCGCGACACCCTCGAACAATGCGCTGGC
CGCCTCATCGGCCAGGACCCGCGCTACATCGAGCGCCTCTGGCAGGATATGGCCCGCTCCTTCTTCTATCCCCCGGGCCG
CGAAAAAATTCACGCCCTCGGCGCCCTCGATCTCGCCCTGTGGGACATCCAGGGGAAGGTCCTCGGCCGCCCCGTCCACG
CCCTCCTCGGCGGCATGGCCCGCAACTTCTGCGAGTGCTACCCCACCGCCGGAGTCATCCCCGGTGTCCGCGGCGGCATG
CCCATCAAAGAACATGCCCAGGCCGTCATGGCGGCGGGCTATCGCGCCTTCCGCATGGGCGCCGCCGATACCCCCGCCAA
TGGCACGTTCAACACCCACGAGCGCCTCAACAAAATGGCCGAAGACTGCGCCCAGGCGCGCGAAGGCGTCGGCAAGAATG
GCGATTGGTGCATCGATTTTCACCAGCGCTTCGATCTCTCCGAAGCCATCCGCGGCTGCGACCTCATCAAGGACTTCGCC
CCCTACTTCGTCGAAGACCCCGTCCGCACCGAAGCCTTCCTCGAGGACATCCCCCTCCTCCGCCGCTCCGCCAAAGTCCC
CATCGCCGCCGGTGAAGAATGGGGCTACCGCTGGGACTTCAACAAGCTGGTCGAAGGTCACGATATCGATTACATCCGCG
CCACGCTTCCCAACGTCGGTGGCATCACCGAGATGATGAAGATCGCCGCCATCTGCGAAACTCACTTCGTCGGCATCATC
CCCCACTTCACCGGCCCCATTGCCACCGCTGCGCTCGTACACGCCCTCGGCGTCTTCTCCGGCCCCGTGCTCGTCGAGTT
CACCTACCAGGGAATAGTAAAGCCCTACCTCCCGGTCTGGCTCGATTTTCGCGAGGGCAAACTCTACCCCAACGATCGCC
CCGGCCTCGGCGTCGAGCTCGATCTCAAGCCGCTCAAGCTCGTCTCCGAAATCACCGAGCGCGTCACCGCCCGCGCCCAG
GTCTACTACCGCCCCGATGGCTCGATAACGAACTGGTAA

Upstream 100 bases:

>100_bases
GTACACTATCGCCCTCGTTAACGAATTTAAAGAAAGCCCGATGGCCTTCCGTCATCCGTGGCGACTGCCAACTCCCACCA
ACAGCGGTACACTTTCATCC

Downstream 100 bases:

>100_bases
CAATAGGAGGACACCCATGCAGCCTCGCCGAAATTTTCTGACCGCCCTCGCCGCGCCCCTTCTCGCGCGCTCCGCTGCAG
CCCAATCCAAGGCCGCGCCC

Product: mandelate racemase/muconate lactonizing protein

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MNRRTLLRSAAAAAGLSLAGRDAARAAIPKMKVTRVRVYSPPNPNPLFNQSDMVVTVETDAGITGIGEGGSRDTLEQCAG
RLIGQDPRYIERLWQDMARSFFYPPGREKIHALGALDLALWDIQGKVLGRPVHALLGGMARNFCECYPTAGVIPGVRGGM
PIKEHAQAVMAAGYRAFRMGAADTPANGTFNTHERLNKMAEDCAQAREGVGKNGDWCIDFHQRFDLSEAIRGCDLIKDFA
PYFVEDPVRTEAFLEDIPLLRRSAKVPIAAGEEWGYRWDFNKLVEGHDIDYIRATLPNVGGITEMMKIAAICETHFVGII
PHFTGPIATAALVHALGVFSGPVLVEFTYQGIVKPYLPVWLDFREGKLYPNDRPGLGVELDLKPLKLVSEITERVTARAQ
VYYRPDGSITNW

Sequences:

>Translated_412_residues
MNRRTLLRSAAAAAGLSLAGRDAARAAIPKMKVTRVRVYSPPNPNPLFNQSDMVVTVETDAGITGIGEGGSRDTLEQCAG
RLIGQDPRYIERLWQDMARSFFYPPGREKIHALGALDLALWDIQGKVLGRPVHALLGGMARNFCECYPTAGVIPGVRGGM
PIKEHAQAVMAAGYRAFRMGAADTPANGTFNTHERLNKMAEDCAQAREGVGKNGDWCIDFHQRFDLSEAIRGCDLIKDFA
PYFVEDPVRTEAFLEDIPLLRRSAKVPIAAGEEWGYRWDFNKLVEGHDIDYIRATLPNVGGITEMMKIAAICETHFVGII
PHFTGPIATAALVHALGVFSGPVLVEFTYQGIVKPYLPVWLDFREGKLYPNDRPGLGVELDLKPLKLVSEITERVTARAQ
VYYRPDGSITNW
>Mature_412_residues
MNRRTLLRSAAAAAGLSLAGRDAARAAIPKMKVTRVRVYSPPNPNPLFNQSDMVVTVETDAGITGIGEGGSRDTLEQCAG
RLIGQDPRYIERLWQDMARSFFYPPGREKIHALGALDLALWDIQGKVLGRPVHALLGGMARNFCECYPTAGVIPGVRGGM
PIKEHAQAVMAAGYRAFRMGAADTPANGTFNTHERLNKMAEDCAQAREGVGKNGDWCIDFHQRFDLSEAIRGCDLIKDFA
PYFVEDPVRTEAFLEDIPLLRRSAKVPIAAGEEWGYRWDFNKLVEGHDIDYIRATLPNVGGITEMMKIAAICETHFVGII
PHFTGPIATAALVHALGVFSGPVLVEFTYQGIVKPYLPVWLDFREGKLYPNDRPGLGVELDLKPLKLVSEITERVTARAQ
VYYRPDGSITNW

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=405, Percent_Identity=31.8518518518519, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1787864, Length=416, Percent_Identity=28.125, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI226510960, Length=355, Percent_Identity=27.6056338028169, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 45426; Mature: 45426

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00908 MR_MLE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRRTLLRSAAAAAGLSLAGRDAARAAIPKMKVTRVRVYSPPNPNPLFNQSDMVVTVETD
CCHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCEEEEEECC
AGITGIGEGGSRDTLEQCAGRLIGQDPRYIERLWQDMARSFFYPPGREKIHALGALDLAL
CCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHE
WDIQGKVLGRPVHALLGGMARNFCECYPTAGVIPGVRGGMPIKEHAQAVMAAGYRAFRMG
EECCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHCCC
AADTPANGTFNTHERLNKMAEDCAQAREGVGKNGDWCIDFHQRFDLSEAIRGCDLIKDFA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHCCHHHHHHHHHHHHHHH
PYFVEDPVRTEAFLEDIPLLRRSAKVPIAAGEEWGYRWDFNKLVEGHDIDYIRATLPNVG
HHHHCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCEECCHHHHCCCCCCHHHHHHCCCCC
GITEMMKIAAICETHFVGIIPHFTGPIATAALVHALGVFSGPVLVEFTYQGIVKPYLPVW
CHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCEE
LDFREGKLYPNDRPGLGVELDLKPLKLVSEITERVTARAQVYYRPDGSITNW
EEEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCEEEEECCCCCCCCC
>Mature Secondary Structure
MNRRTLLRSAAAAAGLSLAGRDAARAAIPKMKVTRVRVYSPPNPNPLFNQSDMVVTVETD
CCHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCEEEEEECC
AGITGIGEGGSRDTLEQCAGRLIGQDPRYIERLWQDMARSFFYPPGREKIHALGALDLAL
CCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHE
WDIQGKVLGRPVHALLGGMARNFCECYPTAGVIPGVRGGMPIKEHAQAVMAAGYRAFRMG
EECCCHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHCCC
AADTPANGTFNTHERLNKMAEDCAQAREGVGKNGDWCIDFHQRFDLSEAIRGCDLIKDFA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHCCHHHHHHHHHHHHHHH
PYFVEDPVRTEAFLEDIPLLRRSAKVPIAAGEEWGYRWDFNKLVEGHDIDYIRATLPNVG
HHHHCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCEECCHHHHCCCCCCHHHHHHCCCCC
GITEMMKIAAICETHFVGIIPHFTGPIATAALVHALGVFSGPVLVEFTYQGIVKPYLPVW
CHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCEE
LDFREGKLYPNDRPGLGVELDLKPLKLVSEITERVTARAQVYYRPDGSITNW
EEEECCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA