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The map label for this gene is atoS [C]

Identifier: 116624106

GI number: 116624106

Start: 6337340

End: 6338884

Strand: Direct

Name: atoS [C]

Synonym: Acid_5021

Alternate gene names: 116624106

Gene position: 6337340-6338884 (Clockwise)

Preceding gene: 116624105

Following gene: 116624108

Centisome position: 63.59

GC content: 61.88

Gene sequence:

>1545_bases
GTGAAAAAGATTACCAATTCAAGTCTGGAGTGCGCTTCTTGGGAGCGTTCAATCCTGGAGTCGCTCGGCGACGCGATCAT
TGTCGTCAGCGCAACCAAACGGGTCGAATTCATGAATCGCGCGGCGGAGAAACTCACCGGCATGGCTGCCGGTAGCGCCT
TCGGCCGCGCGCTGACTGAAGTCCTGCGCCTGGCTCCGGAGTTTGGCGATGAACTCCGCGGCGATTTGGTGGAATTGGCG
ATTCTGAATGGGTCCAGCATCTCGCTCGGGCGCAACCTGATTTTGCGCTCCGACACCGGGGAAGATCGCTCCGTGGAGGG
CGAGATCGCACCTTGCGAAGTGGCGGGAAACCCGCACGGGGCGGTCGTCACCTTCCGCGACGTCACGGAACGCAATCGCC
ACGAGTTGGCGAACTCGCACGATCAAAAGGTCCGCGCTGTGGCTCAACTGGCCGGCTTCATCGCGCACGATCTGAACAAC
GCGCTCACGCTCGTTCTGGGCCACACCGATAGGTTGCTGCGTAATCTGAAGCCCGGCGACCCCTTGCGCGACACCGCGGA
AAACATCAAGGACGCGGGCGACATGGCCGCCAAAGTGAGCGATCAGCTCCGCCTGCTCAGCCGCAGGGAGATCCTGTTGC
CTTCGGTTGTGAATCTCAATTGCGTCATTGAAGACGCCGCCGCCGCGCTCCAAGCCGCGGCGGGGCCGGATATCTCCATC
ACTCGCAACCTCGCGGGGGACCTGGGCGAAATGCGCGCATCCCTGCCGCAATTGCGCGACATGCTGATTAATTTGGTGAC
TCATGCGCGCCAGTCTCTTCCCTTGGGCGGGAAGATTCACGTCGAGACCGCCGACGTCGATATTGCAGGCGAGGAACGAG
CCGGCCGTACGCGTCATTTCATTCGCCTCCGTTTCCACTACTCGGGTCCCGGCATGAAGCTCGAGGATGCCGGGCATATC
TTCGAACCGCGCTTCCGCGCCAGCGGAGACGATGCACAGGATCTTACGATTTTCATGGTGATGGGCGCCGTCTCGGGAGC
GGGCGGACAAATCACCGCGCACGTCGAGCCGGGATGTGTCACGGTGCTTGAGATCCTGATGCCGCGGCTGCAGGCCCCAC
ACCCCATTTTTGCCGGCACCCCGACCGAAGGCGAACCGGCGAAACCGACAGTTCTCCTGGTGGAAGATGATGCCGACGTG
CGTGCGCTGCTCTCTACCTATTTCGACCGTAGCGGCTACCATCTGCTCGAGGCCGAGAACGGCGAGGAGGCCCTGAAGGT
CAGCGAGTTGTACGAGGGGCCGATTGATTTGCTGATCACCGACATGATGATGCCGGTTATGAGCGGACCGCACCTGGTTC
ACGCGATCGCAATGGACCGGCCCGAGACCCGCGTACTCATGATTTCCGGTCTGCCGCCCGACCCCACGGCGCTTGAGGAC
ATGAAGACGCAGGGCGTCCAGTTCCTGCAGAAGCCCTTCCGCAGCGCCGAGCTCCTCCTGCGAGTGAAGGAAATCCTGGT
CGAATCGCGGGCCCGCCTCAATTAA

Upstream 100 bases:

>100_bases
CAGATCCGCATCGCTGTTAAAATTCCGGTAGCGAAAGGTCGCGACCCGGCTAATAAGGTCCCTCCTACCGGCCGCGGTGC
TTTCGGATCTGGGGTCTTCG

Downstream 100 bases:

>100_bases
AAGCAGGGGCGGGCGCTTTCATTTCCAACTTCTGGCTACGAGCGGGACTGGTCATCCCGCTCTTCCCGCCCCCTCACCAT
CAATACGGCATGCCCGCGAT

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MKKITNSSLECASWERSILESLGDAIIVVSATKRVEFMNRAAEKLTGMAAGSAFGRALTEVLRLAPEFGDELRGDLVELA
ILNGSSISLGRNLILRSDTGEDRSVEGEIAPCEVAGNPHGAVVTFRDVTERNRHELANSHDQKVRAVAQLAGFIAHDLNN
ALTLVLGHTDRLLRNLKPGDPLRDTAENIKDAGDMAAKVSDQLRLLSRREILLPSVVNLNCVIEDAAAALQAAAGPDISI
TRNLAGDLGEMRASLPQLRDMLINLVTHARQSLPLGGKIHVETADVDIAGEERAGRTRHFIRLRFHYSGPGMKLEDAGHI
FEPRFRASGDDAQDLTIFMVMGAVSGAGGQITAHVEPGCVTVLEILMPRLQAPHPIFAGTPTEGEPAKPTVLLVEDDADV
RALLSTYFDRSGYHLLEAENGEEALKVSELYEGPIDLLITDMMMPVMSGPHLVHAIAMDRPETRVLMISGLPPDPTALED
MKTQGVQFLQKPFRSAELLLRVKEILVESRARLN

Sequences:

>Translated_514_residues
MKKITNSSLECASWERSILESLGDAIIVVSATKRVEFMNRAAEKLTGMAAGSAFGRALTEVLRLAPEFGDELRGDLVELA
ILNGSSISLGRNLILRSDTGEDRSVEGEIAPCEVAGNPHGAVVTFRDVTERNRHELANSHDQKVRAVAQLAGFIAHDLNN
ALTLVLGHTDRLLRNLKPGDPLRDTAENIKDAGDMAAKVSDQLRLLSRREILLPSVVNLNCVIEDAAAALQAAAGPDISI
TRNLAGDLGEMRASLPQLRDMLINLVTHARQSLPLGGKIHVETADVDIAGEERAGRTRHFIRLRFHYSGPGMKLEDAGHI
FEPRFRASGDDAQDLTIFMVMGAVSGAGGQITAHVEPGCVTVLEILMPRLQAPHPIFAGTPTEGEPAKPTVLLVEDDADV
RALLSTYFDRSGYHLLEAENGEEALKVSELYEGPIDLLITDMMMPVMSGPHLVHAIAMDRPETRVLMISGLPPDPTALED
MKTQGVQFLQKPFRSAELLLRVKEILVESRARLN
>Mature_514_residues
MKKITNSSLECASWERSILESLGDAIIVVSATKRVEFMNRAAEKLTGMAAGSAFGRALTEVLRLAPEFGDELRGDLVELA
ILNGSSISLGRNLILRSDTGEDRSVEGEIAPCEVAGNPHGAVVTFRDVTERNRHELANSHDQKVRAVAQLAGFIAHDLNN
ALTLVLGHTDRLLRNLKPGDPLRDTAENIKDAGDMAAKVSDQLRLLSRREILLPSVVNLNCVIEDAAAALQAAAGPDISI
TRNLAGDLGEMRASLPQLRDMLINLVTHARQSLPLGGKIHVETADVDIAGEERAGRTRHFIRLRFHYSGPGMKLEDAGHI
FEPRFRASGDDAQDLTIFMVMGAVSGAGGQITAHVEPGCVTVLEILMPRLQAPHPIFAGTPTEGEPAKPTVLLVEDDADV
RALLSTYFDRSGYHLLEAENGEEALKVSELYEGPIDLLITDMMMPVMSGPHLVHAIAMDRPETRVLMISGLPPDPTALED
MKTQGVQFLQKPFRSAELLLRVKEILVESRARLN

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=362, Percent_Identity=22.9281767955801, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55835; Mature: 55835

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS00436 PEROXIDASE_2 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKITNSSLECASWERSILESLGDAIIVVSATKRVEFMNRAAEKLTGMAAGSAFGRALTE
CCCCCCCCCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLRLAPEFGDELRGDLVELAILNGSSISLGRNLILRSDTGEDRSVEGEIAPCEVAGNPHG
HHHHHHHHHHHHHCCEEEEEEECCCCEECCCEEEEECCCCCCCCCCCCCCEEEECCCCCC
AVVTFRDVTERNRHELANSHDQKVRAVAQLAGFIAHDLNNALTLVLGHTDRLLRNLKPGD
EEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCC
PLRDTAENIKDAGDMAAKVSDQLRLLSRREILLPSVVNLNCVIEDAAAALQAAAGPDISI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHCCCCCEE
TRNLAGDLGEMRASLPQLRDMLINLVTHARQSLPLGGKIHVETADVDIAGEERAGRTRHF
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCEEE
IRLRFHYSGPGMKLEDAGHIFEPRFRASGDDAQDLTIFMVMGAVSGAGGQITAHVEPGCV
EEEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEEEHHCCCCCCEEEEEECCCHH
TVLEILMPRLQAPHPIFAGTPTEGEPAKPTVLLVEDDADVRALLSTYFDRSGYHLLEAEN
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEECCC
GEEALKVSELYEGPIDLLITDMMMPVMSGPHLVHAIAMDRPETRVLMISGLPPDPTALED
CHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCHHHHH
MKTQGVQFLQKPFRSAELLLRVKEILVESRARLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKITNSSLECASWERSILESLGDAIIVVSATKRVEFMNRAAEKLTGMAAGSAFGRALTE
CCCCCCCCCCHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLRLAPEFGDELRGDLVELAILNGSSISLGRNLILRSDTGEDRSVEGEIAPCEVAGNPHG
HHHHHHHHHHHHHCCEEEEEEECCCCEECCCEEEEECCCCCCCCCCCCCCEEEECCCCCC
AVVTFRDVTERNRHELANSHDQKVRAVAQLAGFIAHDLNNALTLVLGHTDRLLRNLKPGD
EEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCC
PLRDTAENIKDAGDMAAKVSDQLRLLSRREILLPSVVNLNCVIEDAAAALQAAAGPDISI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHCCCCCEE
TRNLAGDLGEMRASLPQLRDMLINLVTHARQSLPLGGKIHVETADVDIAGEERAGRTRHF
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCEEE
IRLRFHYSGPGMKLEDAGHIFEPRFRASGDDAQDLTIFMVMGAVSGAGGQITAHVEPGCV
EEEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEEEHHCCCCCCEEEEEECCCHH
TVLEILMPRLQAPHPIFAGTPTEGEPAKPTVLLVEDDADVRALLSTYFDRSGYHLLEAEN
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEECCC
GEEALKVSELYEGPIDLLITDMMMPVMSGPHLVHAIAMDRPETRVLMISGLPPDPTALED
CHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCCCHHHHH
MKTQGVQFLQKPFRSAELLLRVKEILVESRARLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA