Click here to switch to the map view.

The map label for this gene is macB1 [H]

Identifier: 116623991

GI number: 116623991

Start: 6187596

End: 6190001

Strand: Reverse

Name: macB1 [H]

Synonym: Acid_4903

Alternate gene names: 116623991

Gene position: 6190001-6187596 (Counterclockwise)

Preceding gene: 116623995

Following gene: 116623990

Centisome position: 62.11

GC content: 66.33

Gene sequence:

>2406_bases
ATGTCTGTGCTGCAAGACACGCGCATCGCGCTGCGGCTGCTGGCACGTGCTCCCGCGACCACCGCGATTGCGCTGGTTTC
GATCGCGCTCAGCACGGGCGCGGCGGGAGTGGTCTTCGCGGCGATCAAAGCCGTGCTGCTGAATCCGCTGCCGTATGCGC
GCGCGGAGGAACTGGTGCAGCTGCGCAGCGAGTATCCGCGGATGCAGCAGCAATCGACCGGCGACTGGGTGTTTTGGGAT
GATGCGCAGGAAGTGATTCGCCGAACGCGCACGCTGGAATCGGTAGGCGTATACCGGAACGCGCTGTTCGAGCTTGGCGG
TGACCCATCGAGTCCGCCAGAGGCACTGTACGGATTGCTGATCACACCAAACCTGTTTTCGACGCTGGGAGCGGCGCCAA
TGCTGGGGCGCAATATTCTTCCGGAGGAGGCCGGGCCCGGCCACGCGCAAGTGATGATCTTGAGTTACGGATTGTGGGCG
CGCCGGTTTCATGCAGATCCGCGGATCGTCGGGCGCACGGTCACGGTGAACGCGCACGAGTGCCTGGTGGTCGGAGTGAT
GGCGCCGGAGTTCAACTTTCCGATGCGCCGCTCGGCCGCACACACGCCCTCGCCGTACGTGGAATTCTGGGCCCCGCTGG
TGGTGCGTGCGGGTGCGAGACTCGGCGGCCTCGGCGCGGTTGGGCGGCTGCGGCCGGGCATATCGGCGGCGGAGGCGAGG
CAGGATATCGCGGCGATCGGCGATGCGCTGGCGCGGGAGTTTCCGGCGACGAACCGCGACCGCACCCTGCAGTTGAACCT
GCTGCGCGACCAAACCGTGGGGAATGCGCGTGGTGCGTTGTGGCTGTTGATGGGCGCAACGCTGCTCTTCGTGCTGATCG
GCTGTTCGAACGTTGCCAATCTTCTGCTGGCGCGCGCCACCGCGCGGCGCAATGAGTTCGCGGTACGGATGGCGGTGGGG
GCCGGGCGCGGGCGCATTGTGCGGCAGCTGCTGACGGAGAGTTGCGTGCTCGCACTAGTCGGCGGGGCCGGAGGATTCGC
GCTTGCGGCAGCGGCGTGGAAGGCGCTGCCGGCGTTGGCGCCGGTGAGTATTCCGCGACTGGCCGCGGCGCGCGCGGACT
CCACGGTTTTCTGCTTCTCGCTGGCGATGGGAATGGTGAGCGGGATCCTATTCGGAATGGCGCCCGCGCTGCGTTTGGCG
AGCGGCGGACTGGGTGTACGCGGCGCAGCGGCAACTCGCGATCGATTGCGTCCGGTGCTGGTCGCTATGGAGGTGGCGCT
CTCGGTGGTGCTGGTAGTGATCGGCGGACAACTGCTCGGCAGTTTCCGGCGACTGGTGGCGGCGGATCCGGGATTTCAAG
CCGATCACGTGCTGGCATCGGTGGTGCTGCCCTCGCCGGAACGGTACCGGGATCCCGAACGGAGAGGCTTGTTCTACCGG
CGGATTCTAGATTCGGTGCGCGCGATTCCCGGAGTAGAAGGCGCGGGTACGGTGGATGCGCTGCCATTCAGCGGAGAAAA
TCACGGCGGCTTCGTGTTGGGTTCGCAGAGCGCGCAGCCGTTGACGGCGGAGATCGATGTTGCCGGCGGCGAGTATCTGC
AGACGATGGGGATCCGCCTGGTGGAAGGACGCTGGTTCCGTGAAGAAGAGATGAACGCGTCGAACGATGCCGCGATCGTG
AACACGCTGGTGGCCGGGCGATTGTGGCCGGGAGCGCGGGCGATCGGGCAGCGAATCTGTCTCTATTGCACGCCGGAGAA
TCCGAACAACTGGAAGCGAGTGGTCGGCGTGGTGGCGAGCGCGAGACATGCCTCGCTGAATGAAGCCGAGGCGGGAAACG
TCTATGTAGCCGCTGGGGCGATGCAGACCGCGCAGTTTCTGGTGGTGCGCACGTCGCGGCCGGCGGGAGAGATAGGAACC
GCGATCCGCCGCGCGATTGCGGCGATTGACGCCAACCAGACTGTCTTTCTGACTGCGAGCATGCAGGATTTGATCGGAGA
CTCGGTGGCGGACCGGCGCTTCATCACGATGCTCTTGGCGATCACGGGATGCCTGGCGCTGCTGCTGGCAGCGGCCGGCG
TGTACGGCGTGATCGCGTACAGCACGTCGCGGCGCACGCAGGAGATCGGCATCAGAATGGCGGTGGGGGCGACTCCGGGC
AATGTGTTCGCGCTGATTTTTCGGCAAGGCTTCGCCGCGGTGGCGATGGGCCTCGCGCTCGGGCTGGGTGCGGCAGTGGC
AGCCCTGCGATTGTTGCGGAGTGTGCTGCCAGGATTGGAGTCGGGCCAGAGTGCGTACGTCTGCGCAGCAGTTTCGCTGG
TGACGCTCATGGCCGCGACGGCGTGCTGGCTACCGGCGCGCCGGGCAACGCGGACGGATCCCCTGGAAGCTCTGCGGCAG
GAGTGA

Upstream 100 bases:

>100_bases
GTTTCGAGCAGGGCTAAAAGGTCTTCGCGCGGCAAGAGGTCTGAGGTCGCCATCGAGGTTTGATTATATTACGCGAAGAC
GGCGCGTTAGACTGAAGGCA

Downstream 100 bases:

>100_bases
GCACAGTTCGCCAACTTAAGGATCTTGGATGAGGATAAGGGGGGTGCGCCCTAGAGGGCGATCCCGAGCGATTGCGTGGA
AGCCGCGTGAAAGGCGGCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 801; Mature: 800

Protein sequence:

>801_residues
MSVLQDTRIALRLLARAPATTAIALVSIALSTGAAGVVFAAIKAVLLNPLPYARAEELVQLRSEYPRMQQQSTGDWVFWD
DAQEVIRRTRTLESVGVYRNALFELGGDPSSPPEALYGLLITPNLFSTLGAAPMLGRNILPEEAGPGHAQVMILSYGLWA
RRFHADPRIVGRTVTVNAHECLVVGVMAPEFNFPMRRSAAHTPSPYVEFWAPLVVRAGARLGGLGAVGRLRPGISAAEAR
QDIAAIGDALAREFPATNRDRTLQLNLLRDQTVGNARGALWLLMGATLLFVLIGCSNVANLLLARATARRNEFAVRMAVG
AGRGRIVRQLLTESCVLALVGGAGGFALAAAAWKALPALAPVSIPRLAAARADSTVFCFSLAMGMVSGILFGMAPALRLA
SGGLGVRGAAATRDRLRPVLVAMEVALSVVLVVIGGQLLGSFRRLVAADPGFQADHVLASVVLPSPERYRDPERRGLFYR
RILDSVRAIPGVEGAGTVDALPFSGENHGGFVLGSQSAQPLTAEIDVAGGEYLQTMGIRLVEGRWFREEEMNASNDAAIV
NTLVAGRLWPGARAIGQRICLYCTPENPNNWKRVVGVVASARHASLNEAEAGNVYVAAGAMQTAQFLVVRTSRPAGEIGT
AIRRAIAAIDANQTVFLTASMQDLIGDSVADRRFITMLLAITGCLALLLAAAGVYGVIAYSTSRRTQEIGIRMAVGATPG
NVFALIFRQGFAAVAMGLALGLGAAVAALRLLRSVLPGLESGQSAYVCAAVSLVTLMAATACWLPARRATRTDPLEALRQ
E

Sequences:

>Translated_801_residues
MSVLQDTRIALRLLARAPATTAIALVSIALSTGAAGVVFAAIKAVLLNPLPYARAEELVQLRSEYPRMQQQSTGDWVFWD
DAQEVIRRTRTLESVGVYRNALFELGGDPSSPPEALYGLLITPNLFSTLGAAPMLGRNILPEEAGPGHAQVMILSYGLWA
RRFHADPRIVGRTVTVNAHECLVVGVMAPEFNFPMRRSAAHTPSPYVEFWAPLVVRAGARLGGLGAVGRLRPGISAAEAR
QDIAAIGDALAREFPATNRDRTLQLNLLRDQTVGNARGALWLLMGATLLFVLIGCSNVANLLLARATARRNEFAVRMAVG
AGRGRIVRQLLTESCVLALVGGAGGFALAAAAWKALPALAPVSIPRLAAARADSTVFCFSLAMGMVSGILFGMAPALRLA
SGGLGVRGAAATRDRLRPVLVAMEVALSVVLVVIGGQLLGSFRRLVAADPGFQADHVLASVVLPSPERYRDPERRGLFYR
RILDSVRAIPGVEGAGTVDALPFSGENHGGFVLGSQSAQPLTAEIDVAGGEYLQTMGIRLVEGRWFREEEMNASNDAAIV
NTLVAGRLWPGARAIGQRICLYCTPENPNNWKRVVGVVASARHASLNEAEAGNVYVAAGAMQTAQFLVVRTSRPAGEIGT
AIRRAIAAIDANQTVFLTASMQDLIGDSVADRRFITMLLAITGCLALLLAAAGVYGVIAYSTSRRTQEIGIRMAVGATPG
NVFALIFRQGFAAVAMGLALGLGAAVAALRLLRSVLPGLESGQSAYVCAAVSLVTLMAATACWLPARRATRTDPLEALRQ
E
>Mature_800_residues
SVLQDTRIALRLLARAPATTAIALVSIALSTGAAGVVFAAIKAVLLNPLPYARAEELVQLRSEYPRMQQQSTGDWVFWDD
AQEVIRRTRTLESVGVYRNALFELGGDPSSPPEALYGLLITPNLFSTLGAAPMLGRNILPEEAGPGHAQVMILSYGLWAR
RFHADPRIVGRTVTVNAHECLVVGVMAPEFNFPMRRSAAHTPSPYVEFWAPLVVRAGARLGGLGAVGRLRPGISAAEARQ
DIAAIGDALAREFPATNRDRTLQLNLLRDQTVGNARGALWLLMGATLLFVLIGCSNVANLLLARATARRNEFAVRMAVGA
GRGRIVRQLLTESCVLALVGGAGGFALAAAAWKALPALAPVSIPRLAAARADSTVFCFSLAMGMVSGILFGMAPALRLAS
GGLGVRGAAATRDRLRPVLVAMEVALSVVLVVIGGQLLGSFRRLVAADPGFQADHVLASVVLPSPERYRDPERRGLFYRR
ILDSVRAIPGVEGAGTVDALPFSGENHGGFVLGSQSAQPLTAEIDVAGGEYLQTMGIRLVEGRWFREEEMNASNDAAIVN
TLVAGRLWPGARAIGQRICLYCTPENPNNWKRVVGVVASARHASLNEAEAGNVYVAAGAMQTAQFLVVRTSRPAGEIGTA
IRRAIAAIDANQTVFLTASMQDLIGDSVADRRFITMLLAITGCLALLLAAAGVYGVIAYSTSRRTQEIGIRMAVGATPGN
VFALIFRQGFAAVAMGLALGLGAAVAALRLLRSVLPGLESGQSAYVCAAVSLVTLMAATACWLPARRATRTDPLEALRQE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=317, Percent_Identity=24.9211356466877, Blast_Score=88, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 84752; Mature: 84620

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLQDTRIALRLLARAPATTAIALVSIALSTGAAGVVFAAIKAVLLNPLPYARAEELVQ
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
LRSEYPRMQQQSTGDWVFWDDAQEVIRRTRTLESVGVYRNALFELGGDPSSPPEALYGLL
HHHHCCHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEHE
ITPNLFSTLGAAPMLGRNILPEEAGPGHAQVMILSYGLWARRFHADPRIVGRTVTVNAHE
ECCHHHHHHCCCHHHCCCCCCCCCCCCCEEEEEEEHHHHHHHHCCCCCCEEEEEEECCCC
CLVVGVMAPEFNFPMRRSAAHTPSPYVEFWAPLVVRAGARLGGLGAVGRLRPGISAAEAR
EEEEEEECCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHH
QDIAAIGDALAREFPATNRDRTLQLNLLRDQTVGNARGALWLLMGATLLFVLIGCSNVAN
HHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLLARATARRNEFAVRMAVGAGRGRIVRQLLTESCVLALVGGAGGFALAAAAWKALPALA
HHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
PVSIPRLAAARADSTVFCFSLAMGMVSGILFGMAPALRLASGGLGVRGAAATRDRLRPVL
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
VAMEVALSVVLVVIGGQLLGSFRRLVAADPGFQADHVLASVVLPSPERYRDPERRGLFYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHCCHHHHHHHHH
RILDSVRAIPGVEGAGTVDALPFSGENHGGFVLGSQSAQPLTAEIDVAGGEYLQTMGIRL
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHCCEE
VEGRWFREEEMNASNDAAIVNTLVAGRLWPGARAIGQRICLYCTPENPNNWKRVVGVVAS
ECCCCCCHHHCCCCCCHHHHHHHHHCCCCCCHHHHCCCEEEEECCCCCCHHHHHHHHHHH
ARHASLNEAEAGNVYVAAGAMQTAQFLVVRTSRPAGEIGTAIRRAIAAIDANQTVFLTAS
HHHCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEC
MQDLIGDSVADRRFITMLLAITGCLALLLAAAGVYGVIAYSTSRRTQEIGIRMAVGATPG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHCCEEEEECCCCC
NVFALIFRQGFAAVAMGLALGLGAAVAALRLLRSVLPGLESGQSAYVCAAVSLVTLMAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
ACWLPARRATRTDPLEALRQE
HHHCCCCCCCCCCHHHHHHCC
>Mature Secondary Structure 
SVLQDTRIALRLLARAPATTAIALVSIALSTGAAGVVFAAIKAVLLNPLPYARAEELVQ
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
LRSEYPRMQQQSTGDWVFWDDAQEVIRRTRTLESVGVYRNALFELGGDPSSPPEALYGLL
HHHHCCHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEHE
ITPNLFSTLGAAPMLGRNILPEEAGPGHAQVMILSYGLWARRFHADPRIVGRTVTVNAHE
ECCHHHHHHCCCHHHCCCCCCCCCCCCCEEEEEEEHHHHHHHHCCCCCCEEEEEEECCCC
CLVVGVMAPEFNFPMRRSAAHTPSPYVEFWAPLVVRAGARLGGLGAVGRLRPGISAAEAR
EEEEEEECCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHH
QDIAAIGDALAREFPATNRDRTLQLNLLRDQTVGNARGALWLLMGATLLFVLIGCSNVAN
HHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLLARATARRNEFAVRMAVGAGRGRIVRQLLTESCVLALVGGAGGFALAAAAWKALPALA
HHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
PVSIPRLAAARADSTVFCFSLAMGMVSGILFGMAPALRLASGGLGVRGAAATRDRLRPVL
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
VAMEVALSVVLVVIGGQLLGSFRRLVAADPGFQADHVLASVVLPSPERYRDPERRGLFYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHCCHHHHHHHHH
RILDSVRAIPGVEGAGTVDALPFSGENHGGFVLGSQSAQPLTAEIDVAGGEYLQTMGIRL
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHCCEE
VEGRWFREEEMNASNDAAIVNTLVAGRLWPGARAIGQRICLYCTPENPNNWKRVVGVVAS
ECCCCCCHHHCCCCCCHHHHHHHHHCCCCCCHHHHCCCEEEEECCCCCCHHHHHHHHHHH
ARHASLNEAEAGNVYVAAGAMQTAQFLVVRTSRPAGEIGTAIRRAIAAIDANQTVFLTAS
HHHCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEC
MQDLIGDSVADRRFITMLLAITGCLALLLAAAGVYGVIAYSTSRRTQEIGIRMAVGATPG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHCCEEEEECCCCC
NVFALIFRQGFAAVAMGLALGLGAAVAALRLLRSVLPGLESGQSAYVCAAVSLVTLMAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
ACWLPARRATRTDPLEALRQE
HHHCCCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA