Click here to switch to the map view.

The map label for this gene is yfeW [C]

Identifier: 116623936

GI number: 116623936

Start: 6123371

End: 6124543

Strand: Reverse

Name: yfeW [C]

Synonym: Acid_4848

Alternate gene names: 116623936

Gene position: 6124543-6123371 (Counterclockwise)

Preceding gene: 116623937

Following gene: 116623935

Centisome position: 61.46

GC content: 61.21

Gene sequence:

>1173_bases
ATGAGAATCACTTCGGCTGTCCTCGGCCTGCTCGCCGCCCACACCATCCTTTGCGCGCAGCAGCCCGACCCCTTTGCGGC
CATTGCGCCGCGCATGCAGCAGTTTGTCGATAAGGGCGAGGCATCCGGCATCGTCACTCTGATCGCTACCAGGGATCGAA
TCCTCCACATCGGCGCAGTGGGTAAGAACGACATGTCCGGCGCTCGGAAACTGCGCACCGACGACATCTTCTGGATCGCA
TCCATGAGCAAGCCCCTCACGGCCGTCTGCATCGCAATCCTGGCCGATGACGGCAAGTTGAGTTTCGACGACACTTTGGC
GAAGCATCTGCCCGAGTTCGCCGGCATCATGGTGAACCAGAACGGTCGTAGTGTTCAACCCTCGCGTCCAATCACTTTGC
GCGATGTTCTCACACACACCAGCGGACTCGGCGAGATGACCAATCGCGAGCCGCACCTCACGCTCGCCCAGACCAGCAGG
AACCTGTCGCAGCAGGCGCTGAGCTTTCAACCCGGCAGCCGCTGGTCGTATTCGACCGCCGGCATCGACGTTCTGGGCCG
GGTAGTGGAAGTAGCCGGTGGCATGCCGTTCGACCAGTTCCTGCAGAAGCGCGTCCTCGATCCCCTGGGAATGAAAGACA
CCAGTTTCTGGGTCGCACCCGAAAAGCAATCGCGTTTGGCTCACAGCTATCGCTGGAATGCCCATGCAGGCAGGTTGGCG
GAGACCACCATCCCGTACCTCTACAACACGCCCGTCAAAGATCGCGCCCGCCCGCCGCTCGGCGGCGCCGGCCTGTTCTC
CACAGCCGGGGACATCGCCAGGTTCTATCAAATGATGCTGGGTGGCGGCGCTCTCAATGGCAAGCGCATTCTCAAGCCGG
CGACCGTTGTCGAGATGACACGCAAGCAGACCGGAGATCTCACTGCCCGGCCCGGCATGCCATGGGGACTCGGCTTTTGC
GTGGTGGAAGATCCCTCGAAAATCCCCGGCAATAACGCGCTGTCACCCGGTTCGTTCGGCCACGGCGGGGCATTCAGCAC
GCAAAGCTGGGCCGACCCAACCCGAAACCTGATCTGGGTTCTGATGTTTCAGCGCGACGGTAAGGGCAACCCGGATAACT
CCGACGTCCGCATCGCCTTTCATGAAGGAGCCGCCAATGGTTTGGAAAAATGA

Upstream 100 bases:

>100_bases
GGCCGCCTTGCTCCGCGAGGGCAAGGATGCCTCCGGCATAATGGCCGCATAGCTTACAGTCAGCCCTGCCGGGTAGGTTT
GATACAGTGTTCTCATTCGA

Downstream 100 bases:

>100_bases
TTGCCCGGCAATTTCTTATCTGCGTTCATCTGTGGCCCATGTTGCCTATTTGGAGATCGAATGAACCGAATCGCGATCGT
GTGCCTGTCAATCATCGCCG

Product: beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MRITSAVLGLLAAHTILCAQQPDPFAAIAPRMQQFVDKGEASGIVTLIATRDRILHIGAVGKNDMSGARKLRTDDIFWIA
SMSKPLTAVCIAILADDGKLSFDDTLAKHLPEFAGIMVNQNGRSVQPSRPITLRDVLTHTSGLGEMTNREPHLTLAQTSR
NLSQQALSFQPGSRWSYSTAGIDVLGRVVEVAGGMPFDQFLQKRVLDPLGMKDTSFWVAPEKQSRLAHSYRWNAHAGRLA
ETTIPYLYNTPVKDRARPPLGGAGLFSTAGDIARFYQMMLGGGALNGKRILKPATVVEMTRKQTGDLTARPGMPWGLGFC
VVEDPSKIPGNNALSPGSFGHGGAFSTQSWADPTRNLIWVLMFQRDGKGNPDNSDVRIAFHEGAANGLEK

Sequences:

>Translated_390_residues
MRITSAVLGLLAAHTILCAQQPDPFAAIAPRMQQFVDKGEASGIVTLIATRDRILHIGAVGKNDMSGARKLRTDDIFWIA
SMSKPLTAVCIAILADDGKLSFDDTLAKHLPEFAGIMVNQNGRSVQPSRPITLRDVLTHTSGLGEMTNREPHLTLAQTSR
NLSQQALSFQPGSRWSYSTAGIDVLGRVVEVAGGMPFDQFLQKRVLDPLGMKDTSFWVAPEKQSRLAHSYRWNAHAGRLA
ETTIPYLYNTPVKDRARPPLGGAGLFSTAGDIARFYQMMLGGGALNGKRILKPATVVEMTRKQTGDLTARPGMPWGLGFC
VVEDPSKIPGNNALSPGSFGHGGAFSTQSWADPTRNLIWVLMFQRDGKGNPDNSDVRIAFHEGAANGLEK
>Mature_390_residues
MRITSAVLGLLAAHTILCAQQPDPFAAIAPRMQQFVDKGEASGIVTLIATRDRILHIGAVGKNDMSGARKLRTDDIFWIA
SMSKPLTAVCIAILADDGKLSFDDTLAKHLPEFAGIMVNQNGRSVQPSRPITLRDVLTHTSGLGEMTNREPHLTLAQTSR
NLSQQALSFQPGSRWSYSTAGIDVLGRVVEVAGGMPFDQFLQKRVLDPLGMKDTSFWVAPEKQSRLAHSYRWNAHAGRLA
ETTIPYLYNTPVKDRARPPLGGAGLFSTAGDIARFYQMMLGGGALNGKRILKPATVVEMTRKQTGDLTARPGMPWGLGFC
VVEDPSKIPGNNALSPGSFGHGGAFSTQSWADPTRNLIWVLMFQRDGKGNPDNSDVRIAFHEGAANGLEK

Specific function: Unknown

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI239747261, Length=316, Percent_Identity=27.2151898734177, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI239752721, Length=316, Percent_Identity=27.2151898734177, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI239741085, Length=316, Percent_Identity=27.2151898734177, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI87082101, Length=420, Percent_Identity=26.6666666666667, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786574, Length=286, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17550934, Length=189, Percent_Identity=25.9259259259259, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI115533026, Length=312, Percent_Identity=27.2435897435897, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 42261; Mature: 42261

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITSAVLGLLAAHTILCAQQPDPFAAIAPRMQQFVDKGEASGIVTLIATRDRILHIGAV
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECC
GKNDMSGARKLRTDDIFWIASMSKPLTAVCIAILADDGKLSFDDTLAKHLPEFAGIMVNQ
CCCCCCHHHHCCCCCEEEEEECCCCHHHHHHHHEECCCCCCHHHHHHHHCHHHHCEEECC
NGRSVQPSRPITLRDVLTHTSGLGEMTNREPHLTLAQTSRNLSQQALSFQPGSRWSYSTA
CCCCCCCCCCEEHHHHHHHCCCCCHHCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCHH
GIDVLGRVVEVAGGMPFDQFLQKRVLDPLGMKDTSFWVAPEKQSRLAHSYRWNAHAGRLA
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCCHH
ETTIPYLYNTPVKDRARPPLGGAGLFSTAGDIARFYQMMLGGGALNGKRILKPATVVEMT
HHCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHH
RKQTGDLTARPGMPWGLGFCVVEDPSKIPGNNALSPGSFGHGGAFSTQSWADPTRNLIWV
HHHCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
LMFQRDGKGNPDNSDVRIAFHEGAANGLEK
EEEEECCCCCCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MRITSAVLGLLAAHTILCAQQPDPFAAIAPRMQQFVDKGEASGIVTLIATRDRILHIGAV
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECC
GKNDMSGARKLRTDDIFWIASMSKPLTAVCIAILADDGKLSFDDTLAKHLPEFAGIMVNQ
CCCCCCHHHHCCCCCEEEEEECCCCHHHHHHHHEECCCCCCHHHHHHHHCHHHHCEEECC
NGRSVQPSRPITLRDVLTHTSGLGEMTNREPHLTLAQTSRNLSQQALSFQPGSRWSYSTA
CCCCCCCCCCEEHHHHHHHCCCCCHHCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCHH
GIDVLGRVVEVAGGMPFDQFLQKRVLDPLGMKDTSFWVAPEKQSRLAHSYRWNAHAGRLA
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCCHH
ETTIPYLYNTPVKDRARPPLGGAGLFSTAGDIARFYQMMLGGGALNGKRILKPATVVEMT
HHCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHH
RKQTGDLTARPGMPWGLGFCVVEDPSKIPGNNALSPGSFGHGGAFSTQSWADPTRNLIWV
HHHCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
LMFQRDGKGNPDNSDVRIAFHEGAANGLEK
EEEEECCCCCCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]