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The map label for this gene is mocR [H]

Identifier: 116623891

GI number: 116623891

Start: 6074667

End: 6076094

Strand: Direct

Name: mocR [H]

Synonym: Acid_4803

Alternate gene names: 116623891

Gene position: 6074667-6076094 (Clockwise)

Preceding gene: 116623888

Following gene: 116623892

Centisome position: 60.96

GC content: 67.37

Gene sequence:

>1428_bases
ATGCGTGTCGCATTTACGCTCGACCCGGCGGCGGACGTACCGCTGCACCGGCAGATTTACGAAGAATGGCGGCACGGCAT
CCTGACCGGCCGCTTCCGTCGCGGCGAGCGCGTGCCTTCCACGCGCGAGCTCGCGAGCACCCTGGCCGTTGCGCGGACCA
CGGTCTCCGCCGCCTACGATCAACTGATGGCCGAGGGCTATCTTGATTCCGTCCGCGGCTCCGGCACCTTCGTCTGCCGC
GAACTGCCAGACGAACTGGTGCGGCCGCGCCGCACACCGGCGCCGCGAGCGCAGGCAGAGACGCCCATCCGCCTCTCGCG
CTACGGAGCCGGTCTCCCGGAAACCCGCTTCTGTTACGAGCCGCGGCGCGCCGGTTGGCTGCGTTTCTCGGAGTGGCGGC
CGGACCTCAACGAATTTCCCTTCACCATCTGGCGGAAATTGATGGTCCGCCAGCTCCGCGGGCCGGACTCCCGGTTGTTC
GACTACGCCGACACCGCGACCGGCTACGGCCCCCTGTGCGAAGAGATCGCCGGCTATCTGGCGCGATCGCGCGCCGTGAG
TTGCACGGCGGATCAGGTGCTGATCGTCAACGGCTCCCAACAGGCTCTCGACCTCTGCGCGCGCCTGCTGGTCGATCCGG
GCGACGAGGTAGCCTTCGAAAATCCCGGCTACCAGGGCGCGCGGCAGGTCTTCGCTGCCTGCGGTGCGCGCCTCGCGCCC
GCGCATTTGGACCAGGAAGGCCTCGCCGCGTCCGCCTTGAGTGAACGCGCGCGACTCGTCTATTGCACGCCATCGCACCA
GTTCCCCACCGGCGTCTCGATGCCCGTGACCCGTCGCCTGGAGCTGATCGAATGGGCGCGCCGCCGCGGCGCCGCCATCA
TCGAGGACGACTACGATAGCGAGTACCGCTACAGCGGCCCCCCCATGCCTTCCATGCAGGGTCTTGCAGGCGGCGCACCG
GTCCTCTACATCGGTACTTTTTCCAAGGTGATGTTCCCCGGATTGCGCATCGGCTACGTCATCGTGCCGCCGAAACTTGC
CCCTGCCTTCGCCCGCGGCAAATGGCTCACCGACCGGCAAACGCCCCTGCTCGAACAGGCCGCGCTCGCCGATTTCCTGC
GCGAAGGCCACCTCGAGCGCCACATACGGCGCATGCGGCGATTGTACGGCAGGCGCCGCGCCGTCCTGGTGGAGGCCCTG
GCAAAACACTTCGGCGACCGCGCAACCGTGCTGGGAGACGATGCCGGAATGCATGTGCTGGTGCGCTTCCACAACACTTC
CGTCGTCGAACGCGCCCACGCCAACAAGGTCATCCTCACAGCGTCGGCCCCGTATTACCTGGGTACGGCCCCGAAGGACG
AGTTCGTCTTCGGCTTTTCCTCACTCACCGAGCGCGCCATTCGCGAGGGCATCCGGCGGCTGGTATGA

Upstream 100 bases:

>100_bases
AGTACGGGGGGTAGGGGTGAAGGTCTCCATAGTTAGTAACTGTAGCCCGCAGGGTGGCTCCCGAAAAGATCCACTTTTGA
TATTCTGGATCAGTCCACTT

Downstream 100 bases:

>100_bases
TGAATTCCCAGAATGCAACGCAGGAGTTTTCTCGCAGCGCCGCTCGCGGCATGGCAACTGAAGGCGGCTGAACCCGAGAA
GCGCATTTACGCGTTCGGCG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MRVAFTLDPAADVPLHRQIYEEWRHGILTGRFRRGERVPSTRELASTLAVARTTVSAAYDQLMAEGYLDSVRGSGTFVCR
ELPDELVRPRRTPAPRAQAETPIRLSRYGAGLPETRFCYEPRRAGWLRFSEWRPDLNEFPFTIWRKLMVRQLRGPDSRLF
DYADTATGYGPLCEEIAGYLARSRAVSCTADQVLIVNGSQQALDLCARLLVDPGDEVAFENPGYQGARQVFAACGARLAP
AHLDQEGLAASALSERARLVYCTPSHQFPTGVSMPVTRRLELIEWARRRGAAIIEDDYDSEYRYSGPPMPSMQGLAGGAP
VLYIGTFSKVMFPGLRIGYVIVPPKLAPAFARGKWLTDRQTPLLEQAALADFLREGHLERHIRRMRRLYGRRRAVLVEAL
AKHFGDRATVLGDDAGMHVLVRFHNTSVVERAHANKVILTASAPYYLGTAPKDEFVFGFSSLTERAIREGIRRLV

Sequences:

>Translated_475_residues
MRVAFTLDPAADVPLHRQIYEEWRHGILTGRFRRGERVPSTRELASTLAVARTTVSAAYDQLMAEGYLDSVRGSGTFVCR
ELPDELVRPRRTPAPRAQAETPIRLSRYGAGLPETRFCYEPRRAGWLRFSEWRPDLNEFPFTIWRKLMVRQLRGPDSRLF
DYADTATGYGPLCEEIAGYLARSRAVSCTADQVLIVNGSQQALDLCARLLVDPGDEVAFENPGYQGARQVFAACGARLAP
AHLDQEGLAASALSERARLVYCTPSHQFPTGVSMPVTRRLELIEWARRRGAAIIEDDYDSEYRYSGPPMPSMQGLAGGAP
VLYIGTFSKVMFPGLRIGYVIVPPKLAPAFARGKWLTDRQTPLLEQAALADFLREGHLERHIRRMRRLYGRRRAVLVEAL
AKHFGDRATVLGDDAGMHVLVRFHNTSVVERAHANKVILTASAPYYLGTAPKDEFVFGFSSLTERAIREGIRRLV
>Mature_475_residues
MRVAFTLDPAADVPLHRQIYEEWRHGILTGRFRRGERVPSTRELASTLAVARTTVSAAYDQLMAEGYLDSVRGSGTFVCR
ELPDELVRPRRTPAPRAQAETPIRLSRYGAGLPETRFCYEPRRAGWLRFSEWRPDLNEFPFTIWRKLMVRQLRGPDSRLF
DYADTATGYGPLCEEIAGYLARSRAVSCTADQVLIVNGSQQALDLCARLLVDPGDEVAFENPGYQGARQVFAACGARLAP
AHLDQEGLAASALSERARLVYCTPSHQFPTGVSMPVTRRLELIEWARRRGAAIIEDDYDSEYRYSGPPMPSMQGLAGGAP
VLYIGTFSKVMFPGLRIGYVIVPPKLAPAFARGKWLTDRQTPLLEQAALADFLREGHLERHIRRMRRLYGRRRAVLVEAL
AKHFGDRATVLGDDAGMHVLVRFHNTSVVERAHANKVILTASAPYYLGTAPKDEFVFGFSSLTERAIREGIRRLV

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=292, Percent_Identity=23.2876712328767, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI33469970, Length=292, Percent_Identity=23.2876712328767, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI1790797, Length=385, Percent_Identity=28.051948051948, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787710, Length=408, Percent_Identity=24.7549019607843, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53221; Mature: 53221

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50949 HTH_GNTR ; PS00732 RIBOSOMAL_S16

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAFTLDPAADVPLHRQIYEEWRHGILTGRFRRGERVPSTRELASTLAVARTTVSAAYD
CEEEEECCCCCCCCHHHHHHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QLMAEGYLDSVRGSGTFVCRELPDELVRPRRTPAPRAQAETPIRLSRYGAGLPETRFCYE
HHHHHHHHHHHCCCCCEEEHHCCHHHHCCCCCCCCCCCCCCCEEHHHHCCCCCCCCCCCC
PRRAGWLRFSEWRPDLNEFPFTIWRKLMVRQLRGPDSRLFDYADTATGYGPLCEEIAGYL
CCCCCCEEECCCCCCHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHH
ARSRAVSCTADQVLIVNGSQQALDLCARLLVDPGDEVAFENPGYQGARQVFAACGARLAP
HHHCCCEECCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
AHLDQEGLAASALSERARLVYCTPSHQFPTGVSMPVTRRLELIEWARRRGAAIIEDDYDS
CCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCC
EYRYSGPPMPSMQGLAGGAPVLYIGTFSKVMFPGLRIGYVIVPPKLAPAFARGKWLTDRQ
CCCCCCCCCCCCCCCCCCCCEEEEECHHHHHCCCCEEEEEEECCCCCCHHHCCCCCCCCC
TPLLEQAALADFLREGHLERHIRRMRRLYGRRRAVLVEALAKHFGDRATVLGDDAGMHVL
CHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEE
VRFHNTSVVERAHANKVILTASAPYYLGTAPKDEFVFGFSSLTERAIREGIRRLV
EEECCCHHHHHHCCCEEEEEECCCEEECCCCCCHHEECHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVAFTLDPAADVPLHRQIYEEWRHGILTGRFRRGERVPSTRELASTLAVARTTVSAAYD
CEEEEECCCCCCCCHHHHHHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QLMAEGYLDSVRGSGTFVCRELPDELVRPRRTPAPRAQAETPIRLSRYGAGLPETRFCYE
HHHHHHHHHHHCCCCCEEEHHCCHHHHCCCCCCCCCCCCCCCEEHHHHCCCCCCCCCCCC
PRRAGWLRFSEWRPDLNEFPFTIWRKLMVRQLRGPDSRLFDYADTATGYGPLCEEIAGYL
CCCCCCEEECCCCCCHHCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHH
ARSRAVSCTADQVLIVNGSQQALDLCARLLVDPGDEVAFENPGYQGARQVFAACGARLAP
HHHCCCEECCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
AHLDQEGLAASALSERARLVYCTPSHQFPTGVSMPVTRRLELIEWARRRGAAIIEDDYDS
CCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCC
EYRYSGPPMPSMQGLAGGAPVLYIGTFSKVMFPGLRIGYVIVPPKLAPAFARGKWLTDRQ
CCCCCCCCCCCCCCCCCCCCEEEEECHHHHHCCCCEEEEEEECCCCCCHHHCCCCCCCCC
TPLLEQAALADFLREGHLERHIRRMRRLYGRRRAVLVEALAKHFGDRATVLGDDAGMHVL
CHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEE
VRFHNTSVVERAHANKVILTASAPYYLGTAPKDEFVFGFSSLTERAIREGIRRLV
EEECCCHHHHHHCCCEEEEEECCCEEECCCCCCHHEECHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]