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The map label for this gene is sglT [H]

Identifier: 116623872

GI number: 116623872

Start: 6052395

End: 6053915

Strand: Reverse

Name: sglT [H]

Synonym: Acid_4784

Alternate gene names: 116623872

Gene position: 6053915-6052395 (Counterclockwise)

Preceding gene: 116623874

Following gene: 116623871

Centisome position: 60.75

GC content: 62.59

Gene sequence:

>1521_bases
ATGCGCTACTTCGACCTGGCGATTATCCTCGTCTACCTGATCGCTATTACGCTTTTTGGCGCGCGCTTCCGAAGCGGCCA
GAAGAACCTGCGCGATTACTTCCTGGGCGGGCGCACCGCACCCTGGTGGGCCATCAGCCTGTCGATTGTCTCCGCGGAAA
CCAGCACGCTCACGATTGTCGGAACGCCCGCACTTGCGTTCGGCGGCAACCTGGGCTTTCTCCAGATTGTGTTCGGCTAC
CTGCTGGCCCGCATCGTGATCTCGTTTGTGTTTCTTCCCCAATACTTCAAAGGCGAGATGTTCACAGCCTACGAACTCAT
GCGCCGGCGTTTTGGCGAACGGGTCCGCAAGCTCACCGCCTCTATATTCCTTGTGACGCGCGCTCTCGCCGAAGGTGTAC
GGGTGTTCGCTATTTCGCTGGTCATCTCGATTGTCCTGGGCACGGGTGAAATCGCTTCCATCGTCCTGATCGTACTGCTG
ACGCTTTTTTATACTTTCGAAGGCGGCATGACCGCCGTGATCTGGACGGATGTGGTGCAGATGACGCTCTATATTATCGG
CGCCATCGCCAGCTTCGCCATCATCCTCGGCAAAATTCCCGGCGGCTGGGAACACGTCTCGGCGGTGGCCGGCGCCGCCC
ACAAATTTACGGTATTCGATTTCCGCTTCGCCTTCGACATGCAGTTTTTCGCCCGCACCTACAGCTTCTGGGCCGGAGTT
GCGGGCGGCTGCTTCCTGACCACCGCCAGCCACGGCACCGATCAACTCATGGTGCAGCGGCTGCTCAGCGCGCGCGACGA
GCGGCAGAGCCGCACGGCGCTGTTCGCCAGCTGGGTCGTGATCTTTTTCCAATTCACGCTCTTCCTTCTAATTGGCGTAC
TGCTCTTTGTGTACTACGGCGACCAGGGGCTCAACGCGCCGGCGCAGAAGGACCGTATTTATCCGGAGTTCGTCTGGCAC
AACCTGCCCCCCGGACTGGCCGGACTGATTATCGCGGCCATCCTCGCAGCCGCGATGGCCAACCTCAGCGCCGCGCTCAA
TTCGCTGGCCTCCACCACGGTTGTCGATTTCTACCGCGCGAGGGCCAAATCCCTGAGCGACGCCTCCGCGCTCAAGATCG
CCCGGTGGGCTACGATCGCCTGGGGTCTGGTGCTGCTTGCCATCGCGATTGCGGCGCGCGGTTCCACGTCGGTGCTCGAG
GCGGGGCTCACGATCGGCTCCATCCCGATGGGGGCGCTGCTCGGCGTTTTCCTGCTCGGCGTGCTCACCAGGAAGCCGCG
CGAAGGCGCCGCGATCGCGGGGGTCGCATGCGGGCTCGCGGCGGTCCTCGGAACGCGGTTCTTTACGCCGGTGGCCTGGA
CCTGGTATGTCCTGATCGGCACCGTCACTACCTTTGGCGTAGGTCTGGCAGCCTCATTGTTTGAAGGCCCCGCACCGCTG
CCGCCCGCAGAGGCCGGCGTCCGAGAGCCGGTCGGGGGACCTTCGAATTCGCCGCCACATCGCGCCAGTCCGGAGATCTA
A

Upstream 100 bases:

>100_bases
TCCAAATCATAGCAGAGGAAGATCATTGCCCCAACAAACATGACCAAAACGTGACCAAATCGGGTGCGGAAGAGTATGCT
GGTAGCTCGCACACCATCCG

Downstream 100 bases:

>100_bases
CCAGAGGAATCGACCGCTCATGCAAAAGTCACCCCGCACGGAATTGAAACGCGACCTCGGCCCGTGGGCCGCGGCATCCA
TCGTAGTCGGCACGGTCATA

Product: SSS family solute/sodium (Na+) symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MRYFDLAIILVYLIAITLFGARFRSGQKNLRDYFLGGRTAPWWAISLSIVSAETSTLTIVGTPALAFGGNLGFLQIVFGY
LLARIVISFVFLPQYFKGEMFTAYELMRRRFGERVRKLTASIFLVTRALAEGVRVFAISLVISIVLGTGEIASIVLIVLL
TLFYTFEGGMTAVIWTDVVQMTLYIIGAIASFAIILGKIPGGWEHVSAVAGAAHKFTVFDFRFAFDMQFFARTYSFWAGV
AGGCFLTTASHGTDQLMVQRLLSARDERQSRTALFASWVVIFFQFTLFLLIGVLLFVYYGDQGLNAPAQKDRIYPEFVWH
NLPPGLAGLIIAAILAAAMANLSAALNSLASTTVVDFYRARAKSLSDASALKIARWATIAWGLVLLAIAIAARGSTSVLE
AGLTIGSIPMGALLGVFLLGVLTRKPREGAAIAGVACGLAAVLGTRFFTPVAWTWYVLIGTVTTFGVGLAASLFEGPAPL
PPAEAGVREPVGGPSNSPPHRASPEI

Sequences:

>Translated_506_residues
MRYFDLAIILVYLIAITLFGARFRSGQKNLRDYFLGGRTAPWWAISLSIVSAETSTLTIVGTPALAFGGNLGFLQIVFGY
LLARIVISFVFLPQYFKGEMFTAYELMRRRFGERVRKLTASIFLVTRALAEGVRVFAISLVISIVLGTGEIASIVLIVLL
TLFYTFEGGMTAVIWTDVVQMTLYIIGAIASFAIILGKIPGGWEHVSAVAGAAHKFTVFDFRFAFDMQFFARTYSFWAGV
AGGCFLTTASHGTDQLMVQRLLSARDERQSRTALFASWVVIFFQFTLFLLIGVLLFVYYGDQGLNAPAQKDRIYPEFVWH
NLPPGLAGLIIAAILAAAMANLSAALNSLASTTVVDFYRARAKSLSDASALKIARWATIAWGLVLLAIAIAARGSTSVLE
AGLTIGSIPMGALLGVFLLGVLTRKPREGAAIAGVACGLAAVLGTRFFTPVAWTWYVLIGTVTTFGVGLAASLFEGPAPL
PPAEAGVREPVGGPSNSPPHRASPEI
>Mature_506_residues
MRYFDLAIILVYLIAITLFGARFRSGQKNLRDYFLGGRTAPWWAISLSIVSAETSTLTIVGTPALAFGGNLGFLQIVFGY
LLARIVISFVFLPQYFKGEMFTAYELMRRRFGERVRKLTASIFLVTRALAEGVRVFAISLVISIVLGTGEIASIVLIVLL
TLFYTFEGGMTAVIWTDVVQMTLYIIGAIASFAIILGKIPGGWEHVSAVAGAAHKFTVFDFRFAFDMQFFARTYSFWAGV
AGGCFLTTASHGTDQLMVQRLLSARDERQSRTALFASWVVIFFQFTLFLLIGVLLFVYYGDQGLNAPAQKDRIYPEFVWH
NLPPGLAGLIIAAILAAAMANLSAALNSLASTTVVDFYRARAKSLSDASALKIARWATIAWGLVLLAIAIAARGSTSVLE
AGLTIGSIPMGALLGVFLLGVLTRKPREGAAIAGVACGLAAVLGTRFFTPVAWTWYVLIGTVTTFGVGLAASLFEGPAPL
PPAEAGVREPVGGPSNSPPHRASPEI

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI4507035, Length=512, Percent_Identity=27.734375, Blast_Score=172, Evalue=8e-43,
Organism=Homo sapiens, GI157671931, Length=418, Percent_Identity=27.0334928229665, Blast_Score=166, Evalue=7e-41,
Organism=Homo sapiens, GI256985183, Length=448, Percent_Identity=30.1339285714286, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI167466278, Length=461, Percent_Identity=28.1995661605206, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI109659836, Length=482, Percent_Identity=25.103734439834, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI14140236, Length=520, Percent_Identity=22.5, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI4507031, Length=466, Percent_Identity=24.2489270386266, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI109659839, Length=498, Percent_Identity=25.1004016064257, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI17941285, Length=406, Percent_Identity=23.8916256157635, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI110835708, Length=407, Percent_Identity=24.5700245700246, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI4507033, Length=406, Percent_Identity=22.6600985221675, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI206597483, Length=448, Percent_Identity=23.4375, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI206597487, Length=473, Percent_Identity=22.8329809725159, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32566512, Length=364, Percent_Identity=24.7252747252747, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115533094, Length=428, Percent_Identity=25.4672897196262, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI115533096, Length=315, Percent_Identity=24.4444444444444, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24651739, Length=451, Percent_Identity=26.3858093126386, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI28573698, Length=446, Percent_Identity=27.8026905829596, Blast_Score=148, Evalue=8e-36,
Organism=Drosophila melanogaster, GI221459584, Length=424, Percent_Identity=28.5377358490566, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI221459588, Length=427, Percent_Identity=28.1030444964871, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281362918, Length=423, Percent_Identity=27.1867612293144, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI281362054, Length=450, Percent_Identity=26.6666666666667, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI281362052, Length=450, Percent_Identity=26.6666666666667, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI281362050, Length=450, Percent_Identity=26.6666666666667, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24648056, Length=450, Percent_Identity=26.6666666666667, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI21356827, Length=450, Percent_Identity=26.6666666666667, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24651741, Length=448, Percent_Identity=24.1071428571429, Blast_Score=135, Evalue=6e-32,
Organism=Drosophila melanogaster, GI28574994, Length=444, Percent_Identity=25.6756756756757, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24645928, Length=426, Percent_Identity=25.5868544600939, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24640370, Length=399, Percent_Identity=27.5689223057644, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24641117, Length=459, Percent_Identity=26.5795206971678, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI221459586, Length=431, Percent_Identity=26.4501160092807, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI161076631, Length=419, Percent_Identity=24.1050119331742, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19920916, Length=434, Percent_Identity=25.8064516129032, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24650192, Length=406, Percent_Identity=23.3990147783251, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281364280, Length=431, Percent_Identity=24.8259860788863, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI221379702, Length=419, Percent_Identity=26.7303102625298, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI221459582, Length=407, Percent_Identity=25.3071253071253, Blast_Score=99, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 54516; Mature: 54516

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYFDLAIILVYLIAITLFGARFRSGQKNLRDYFLGGRTAPWWAISLSIVSAETSTLTIV
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEEEEEEECCCEEEEE
GTPALAFGGNLGFLQIVFGYLLARIVISFVFLPQYFKGEMFTAYELMRRRFGERVRKLTA
ECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SIFLVTRALAEGVRVFAISLVISIVLGTGEIASIVLIVLLTLFYTFEGGMTAVIWTDVVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
MTLYIIGAIASFAIILGKIPGGWEHVSAVAGAAHKFTVFDFRFAFDMQFFARTYSFWAGV
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHC
AGGCFLTTASHGTDQLMVQRLLSARDERQSRTALFASWVVIFFQFTLFLLIGVLLFVYYG
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DQGLNAPAQKDRIYPEFVWHNLPPGLAGLIIAAILAAAMANLSAALNSLASTTVVDFYRA
CCCCCCCHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAKSLSDASALKIARWATIAWGLVLLAIAIAARGSTSVLEAGLTIGSIPMGALLGVFLLG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHH
VLTRKPREGAAIAGVACGLAAVLGTRFFTPVAWTWYVLIGTVTTFGVGLAASLFEGPAPL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PPAEAGVREPVGGPSNSPPHRASPEI
CCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRYFDLAIILVYLIAITLFGARFRSGQKNLRDYFLGGRTAPWWAISLSIVSAETSTLTIV
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEEEEEEECCCEEEEE
GTPALAFGGNLGFLQIVFGYLLARIVISFVFLPQYFKGEMFTAYELMRRRFGERVRKLTA
ECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SIFLVTRALAEGVRVFAISLVISIVLGTGEIASIVLIVLLTLFYTFEGGMTAVIWTDVVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
MTLYIIGAIASFAIILGKIPGGWEHVSAVAGAAHKFTVFDFRFAFDMQFFARTYSFWAGV
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHC
AGGCFLTTASHGTDQLMVQRLLSARDERQSRTALFASWVVIFFQFTLFLLIGVLLFVYYG
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DQGLNAPAQKDRIYPEFVWHNLPPGLAGLIIAAILAAAMANLSAALNSLASTTVVDFYRA
CCCCCCCHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAKSLSDASALKIARWATIAWGLVLLAIAIAARGSTSVLEAGLTIGSIPMGALLGVFLLG
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHH
VLTRKPREGAAIAGVACGLAAVLGTRFFTPVAWTWYVLIGTVTTFGVGLAASLFEGPAPL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PPAEAGVREPVGGPSNSPPHRASPEI
CCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]