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The map label for this gene is steT [H]

Identifier: 116623871

GI number: 116623871

Start: 6050990

End: 6052375

Strand: Reverse

Name: steT [H]

Synonym: Acid_4783

Alternate gene names: 116623871

Gene position: 6052375-6050990 (Counterclockwise)

Preceding gene: 116623872

Following gene: 116623864

Centisome position: 60.73

GC content: 55.92

Gene sequence:

>1386_bases
ATGCAAAAGTCACCCCGCACGGAATTGAAACGCGACCTCGGCCCGTGGGCCGCGGCATCCATCGTAGTCGGCACGGTCAT
AGGCAGCGGCATCTTCCTGGTTCCGAAGACGATGATCCAGAAGGTCGGGACGGTGGAAGCGGTCTTCGCGGTCTGGGTGG
TCGGCGGACTGCTGTCGCTTGCCGGAGCGCTCAGCTATGCCGAACTCGCCGCCGCGCTCCCGGAGGCAGGAGGCGAATAC
GCCTTCCTTCGAGAGGCGTATGGGCCGATGTGGGGTTTCCTGTATAGCTGGACGCAGATGTGGGTCGCAAAAAGCGGCTC
CATCGCCACTCTTGCTACCGGATTTTTTTTATACCTGACGACTTTCTTTGAACCCTTAAAGGGTGTTTTTTATACAATTC
CTCTGCCGATTGGCCCCAATGGAGGGCCGCTTGAGATTCAATACGGGCAGATATTCGCTATTTTTCTGATTCTTGCGCTT
GGCTGGCTGAACTATTTCGGCGTGCGGATCGGCGGCAATGTGCAGGTTGCCGTGACTGTGATCAAAGTCGGCCTCATCGC
GGCTATCATATTCGCAGGATTGGTCTTCGGCCACGCGCACGAGACTGCGGCAGGCCCAGTCGCGCCAATCACGTTTTCGG
GTTTTATCGCCGCTCTGGTAGCCGCTCTGTGGGCCTACGACGGTTGGAATAACGTGAGTATGGTGTCTTCGGAAATAAAA
GACCCGCAGAAGAATCTTCCGCGGGCGTTAATCGGCGGGACCTTATGCGTGATTGCAATTTATATGGCCGCGAATGCCGC
CTATTTCCACGTCATGTCGCCCGCCGAGGTAGCCGGGAGCACGCGTGTCGCCGCCGAAATGATGCGCAAAATCTTCAGCG
CTCCCGGAGCCGCCGCCGTCTCGATCGCCGCCATGATCAGTATTTTCGCGGCTTTGAACGGCTCGATCCTTTCCGGCGCG
CGCGTGCCTTATGCGGCCGCTCGCGACGGGTATTTCTTTCACGCCATCGGACGCGTTCATCCTAAATATCACACACCGGG
AGTTTCCATCATCGTGCTCAATCTTTGGGCTTGTCTCTTAGTCCTTTCCGGGAAATATGACGACCTATTTAACCTCGTAA
TTTTCGCCAGTTGGATTCTCTACGGCATGACCGCCGCCGCGGTGGTTGTGCTCCGTATCAAGCAGCCGGAGCTTCAGCGC
CCGTATCGTACGATGGGTTATCCGGTGGTTCCGGTGCTTTTTATAATTGGTGCGGTAATTCTCCTGGTTTCAACCGCTTG
GGAGCGGCCGCGCGAATCCATGATGGGCATTGCTCTAATTTTGCTCGGGCTGCCGTTTTACTATTATTGGAAAAAACGTA
TTCCAGCTACAATTCGAGAGGTTTGA

Upstream 100 bases:

>100_bases
CCGCCCGCAGAGGCCGGCGTCCGAGAGCCGGTCGGGGGACCTTCGAATTCGCCGCCACATCGCGCCAGTCCGGAGATCTA
ACCAGAGGAATCGACCGCTC

Downstream 100 bases:

>100_bases
CCGTACTAGGCCCCACATTCGGTACTTTCGTTCTATTAAATTGACCCAAAAATCGCATTTCATATCTTGAATTTCCGGCT
CAATAGGTAGAAGATTTGAA

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MQKSPRTELKRDLGPWAAASIVVGTVIGSGIFLVPKTMIQKVGTVEAVFAVWVVGGLLSLAGALSYAELAAALPEAGGEY
AFLREAYGPMWGFLYSWTQMWVAKSGSIATLATGFFLYLTTFFEPLKGVFYTIPLPIGPNGGPLEIQYGQIFAIFLILAL
GWLNYFGVRIGGNVQVAVTVIKVGLIAAIIFAGLVFGHAHETAAGPVAPITFSGFIAALVAALWAYDGWNNVSMVSSEIK
DPQKNLPRALIGGTLCVIAIYMAANAAYFHVMSPAEVAGSTRVAAEMMRKIFSAPGAAAVSIAAMISIFAALNGSILSGA
RVPYAAARDGYFFHAIGRVHPKYHTPGVSIIVLNLWACLLVLSGKYDDLFNLVIFASWILYGMTAAAVVVLRIKQPELQR
PYRTMGYPVVPVLFIIGAVILLVSTAWERPRESMMGIALILLGLPFYYYWKKRIPATIREV

Sequences:

>Translated_461_residues
MQKSPRTELKRDLGPWAAASIVVGTVIGSGIFLVPKTMIQKVGTVEAVFAVWVVGGLLSLAGALSYAELAAALPEAGGEY
AFLREAYGPMWGFLYSWTQMWVAKSGSIATLATGFFLYLTTFFEPLKGVFYTIPLPIGPNGGPLEIQYGQIFAIFLILAL
GWLNYFGVRIGGNVQVAVTVIKVGLIAAIIFAGLVFGHAHETAAGPVAPITFSGFIAALVAALWAYDGWNNVSMVSSEIK
DPQKNLPRALIGGTLCVIAIYMAANAAYFHVMSPAEVAGSTRVAAEMMRKIFSAPGAAAVSIAAMISIFAALNGSILSGA
RVPYAAARDGYFFHAIGRVHPKYHTPGVSIIVLNLWACLLVLSGKYDDLFNLVIFASWILYGMTAAAVVVLRIKQPELQR
PYRTMGYPVVPVLFIIGAVILLVSTAWERPRESMMGIALILLGLPFYYYWKKRIPATIREV
>Mature_461_residues
MQKSPRTELKRDLGPWAAASIVVGTVIGSGIFLVPKTMIQKVGTVEAVFAVWVVGGLLSLAGALSYAELAAALPEAGGEY
AFLREAYGPMWGFLYSWTQMWVAKSGSIATLATGFFLYLTTFFEPLKGVFYTIPLPIGPNGGPLEIQYGQIFAIFLILAL
GWLNYFGVRIGGNVQVAVTVIKVGLIAAIIFAGLVFGHAHETAAGPVAPITFSGFIAALVAALWAYDGWNNVSMVSSEIK
DPQKNLPRALIGGTLCVIAIYMAANAAYFHVMSPAEVAGSTRVAAEMMRKIFSAPGAAAVSIAAMISIFAALNGSILSGA
RVPYAAARDGYFFHAIGRVHPKYHTPGVSIIVLNLWACLLVLSGKYDDLFNLVIFASWILYGMTAAAVVVLRIKQPELQR
PYRTMGYPVVPVLFIIGAVILLVSTAWERPRESMMGIALILLGLPFYYYWKKRIPATIREV

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI187423910, Length=458, Percent_Identity=32.0960698689956, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI7657591, Length=458, Percent_Identity=32.0960698689956, Blast_Score=226, Evalue=5e-59,
Organism=Homo sapiens, GI33286428, Length=464, Percent_Identity=31.4655172413793, Blast_Score=205, Evalue=7e-53,
Organism=Homo sapiens, GI115648063, Length=469, Percent_Identity=29.8507462686567, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI115648022, Length=469, Percent_Identity=29.8507462686567, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI71979932, Length=456, Percent_Identity=28.9473684210526, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI186910308, Length=463, Percent_Identity=28.7257019438445, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI186910306, Length=463, Percent_Identity=28.7257019438445, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI186910304, Length=463, Percent_Identity=28.7257019438445, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI7657683, Length=462, Percent_Identity=29.2207792207792, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI9790235, Length=460, Percent_Identity=28.9130434782609, Blast_Score=162, Evalue=9e-40,
Organism=Homo sapiens, GI33286430, Length=240, Percent_Identity=32.5, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI71999149, Length=432, Percent_Identity=24.0740740740741, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI4507047, Length=419, Percent_Identity=23.6276849642005, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI258614003, Length=424, Percent_Identity=23.8207547169811, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI258614005, Length=424, Percent_Identity=23.8207547169811, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI258645169, Length=424, Percent_Identity=23.3490566037736, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI114326544, Length=420, Percent_Identity=22.3809523809524, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI114326550, Length=420, Percent_Identity=22.3809523809524, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI110347453, Length=396, Percent_Identity=24.2424242424242, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI181337167, Length=389, Percent_Identity=23.3933161953728, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87082250, Length=457, Percent_Identity=29.5404814004376, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI2367353, Length=348, Percent_Identity=28.1609195402299, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786908, Length=382, Percent_Identity=23.0366492146597, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17540018, Length=474, Percent_Identity=27.0042194092827, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI193208714, Length=438, Percent_Identity=27.1689497716895, Blast_Score=159, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI32566695, Length=438, Percent_Identity=27.1689497716895, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI71982612, Length=452, Percent_Identity=27.4336283185841, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI71982608, Length=452, Percent_Identity=27.4336283185841, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17568033, Length=463, Percent_Identity=28.5097192224622, Blast_Score=151, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI71993915, Length=456, Percent_Identity=26.5350877192982, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI71995388, Length=462, Percent_Identity=25.1082251082251, Blast_Score=138, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71995382, Length=462, Percent_Identity=25.7575757575758, Blast_Score=138, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI32566699, Length=441, Percent_Identity=26.3038548752834, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71982623, Length=284, Percent_Identity=29.5774647887324, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71990446, Length=468, Percent_Identity=24.3589743589744, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17532491, Length=401, Percent_Identity=22.4438902743142, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17531343, Length=414, Percent_Identity=22.463768115942, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17533459, Length=401, Percent_Identity=21.6957605985037, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71987339, Length=232, Percent_Identity=24.5689655172414, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321751, Length=342, Percent_Identity=27.4853801169591, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24641993, Length=449, Percent_Identity=33.8530066815145, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24641995, Length=449, Percent_Identity=33.8530066815145, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI21357367, Length=483, Percent_Identity=30.4347826086957, Blast_Score=208, Evalue=8e-54,
Organism=Drosophila melanogaster, GI24651635, Length=459, Percent_Identity=30.0653594771242, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24651633, Length=459, Percent_Identity=30.0653594771242, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI45550968, Length=452, Percent_Identity=31.1946902654867, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI19921172, Length=452, Percent_Identity=31.1946902654867, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI221331183, Length=445, Percent_Identity=31.0112359550562, Blast_Score=191, Evalue=9e-49,
Organism=Drosophila melanogaster, GI17647653, Length=445, Percent_Identity=31.0112359550562, Blast_Score=191, Evalue=9e-49,
Organism=Drosophila melanogaster, GI24664379, Length=445, Percent_Identity=31.0112359550562, Blast_Score=191, Evalue=9e-49,
Organism=Drosophila melanogaster, GI24667468, Length=407, Percent_Identity=22.6044226044226, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24666159, Length=422, Percent_Identity=21.563981042654, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221512776, Length=422, Percent_Identity=21.563981042654, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI161077963, Length=395, Percent_Identity=23.2911392405063, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281366235, Length=407, Percent_Identity=22.1130221130221, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI116007820, Length=407, Percent_Identity=22.1130221130221, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24668806, Length=424, Percent_Identity=20.5188679245283, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356285, Length=424, Percent_Identity=20.5188679245283, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24668802, Length=424, Percent_Identity=20.5188679245283, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007818, Length=417, Percent_Identity=23.2613908872902, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI85725152, Length=417, Percent_Identity=23.2613908872902, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49657; Mature: 49657

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKSPRTELKRDLGPWAAASIVVGTVIGSGIFLVPKTMIQKVGTVEAVFAVWVVGGLLSL
CCCCCHHHHHHHCCCHHHHHHHHHHHHCCCHHEECHHHHHHHCHHHHHHHHHHHHHHHHH
AGALSYAELAAALPEAGGEYAFLREAYGPMWGFLYSWTQMWVAKSGSIATLATGFFLYLT
HHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TFFEPLKGVFYTIPLPIGPNGGPLEIQYGQIFAIFLILALGWLNYFGVRIGGNVQVAVTV
HHHHHHCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCEEECCCEEEHHHH
IKVGLIAAIIFAGLVFGHAHETAAGPVAPITFSGFIAALVAALWAYDGWNNVSMVSSEIK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
DPQKNLPRALIGGTLCVIAIYMAANAAYFHVMSPAEVAGSTRVAAEMMRKIFSAPGAAAV
CCHHHCCHHHHHHHHHHHHHHHHHCCCEEEECCHHHHCCHHHHHHHHHHHHHCCCCHHHH
SIAAMISIFAALNGSILSGARVPYAAARDGYFFHAIGRVHPKYHTPGVSIIVLNLWACLL
HHHHHHHHHHHHCCCHHCCCCCCCHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
VLSGKYDDLFNLVIFASWILYGMTAAAVVVLRIKQPELQRPYRTMGYPVVPVLFIIGAVI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHCCCHHHCCCCHHHHHHHHHHHH
LLVSTAWERPRESMMGIALILLGLPFYYYWKKRIPATIREV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure
MQKSPRTELKRDLGPWAAASIVVGTVIGSGIFLVPKTMIQKVGTVEAVFAVWVVGGLLSL
CCCCCHHHHHHHCCCHHHHHHHHHHHHCCCHHEECHHHHHHHCHHHHHHHHHHHHHHHHH
AGALSYAELAAALPEAGGEYAFLREAYGPMWGFLYSWTQMWVAKSGSIATLATGFFLYLT
HHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TFFEPLKGVFYTIPLPIGPNGGPLEIQYGQIFAIFLILALGWLNYFGVRIGGNVQVAVTV
HHHHHHCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCEEECCCEEEHHHH
IKVGLIAAIIFAGLVFGHAHETAAGPVAPITFSGFIAALVAALWAYDGWNNVSMVSSEIK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHC
DPQKNLPRALIGGTLCVIAIYMAANAAYFHVMSPAEVAGSTRVAAEMMRKIFSAPGAAAV
CCHHHCCHHHHHHHHHHHHHHHHHCCCEEEECCHHHHCCHHHHHHHHHHHHHCCCCHHHH
SIAAMISIFAALNGSILSGARVPYAAARDGYFFHAIGRVHPKYHTPGVSIIVLNLWACLL
HHHHHHHHHHHHCCCHHCCCCCCCHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
VLSGKYDDLFNLVIFASWILYGMTAAAVVVLRIKQPELQRPYRTMGYPVVPVLFIIGAVI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHCCCHHHCCCCHHHHHHHHHHHH
LLVSTAWERPRESMMGIALILLGLPFYYYWKKRIPATIREV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]