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The map label for this gene is coaE [H]

Identifier: 116623869

GI number: 116623869

Start: 6048476

End: 6049081

Strand: Direct

Name: coaE [H]

Synonym: Acid_4781

Alternate gene names: 116623869

Gene position: 6048476-6049081 (Clockwise)

Preceding gene: 116623868

Following gene: 116623870

Centisome position: 60.69

GC content: 59.74

Gene sequence:

>606_bases
ATGCTGAAGGTTGGGCTGACTGGTGGAATTGGCTGTGGCAAGAGCTTCGTGGGTGAGGCGCTGGCAGACTACGGGTGCCT
GGTGGTTCACGCGGACGACTTGGGACATGAAGTGCTCGCGCGCGGGGGAGCCGGATACGCACTGGTGGTAGCGGAATTCG
GCAGGGAAATCCTGGACGATAAGGGCGAGATCGACCGGAAGGCGCTGGGAGCGCTGGTTTTCGGCTACCCCGAGCGCCTG
GACCGGCTGAATGCGATTGTGCATCCGGCAGTGATCCGGCGCGAAGAGGAGTTGCTGGCCGAATTTGCGGCACGTCATCC
GGATGGAATTGCGGTAGTGGAAGCCGCCATCCTGGTGGAAACCGGGAGCTACAAACGCTTTGATAAGTTGGTTTTAGTGA
CTTGCAGGGAAGAACAACAGGTGGAGCGCGCAATGCGGCGCGAGGGAGCGTCGGAGGGTGACGTTCGGGCCCGCATCGGG
CGGCAGATGCCCCTTGCGGAGAAACGAAAGTTTGCAGATTTCGTCATAGATACATCCGGGGAGAAAGCGGATACCTTACG
GCAGACCCGGGCCGTCTACGACACATTACGGAGAATCGAATCATGA

Upstream 100 bases:

>100_bases
AGGCCGGGGCGTACACGCCCGTGCCGGGCGGCGTCGGACCGCTCACGATCGCGATGCTGATGGTCAATACGGTGGCCTCG
GCGGAGCGTCGAGCGGGCGT

Downstream 100 bases:

>100_bases
GAGTGCTGCGTACCTTCTTTTGGGCTGCCGTTCTGGCCGCTGGTTTCATCTGGGTCACCAGCGTGGCCAACTGGGATGTG
GGGCGCGCGCTGCGTCCCGT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MLKVGLTGGIGCGKSFVGEALADYGCLVVHADDLGHEVLARGGAGYALVVAEFGREILDDKGEIDRKALGALVFGYPERL
DRLNAIVHPAVIRREEELLAEFAARHPDGIAVVEAAILVETGSYKRFDKLVLVTCREEQQVERAMRREGASEGDVRARIG
RQMPLAEKRKFADFVIDTSGEKADTLRQTRAVYDTLRRIES

Sequences:

>Translated_201_residues
MLKVGLTGGIGCGKSFVGEALADYGCLVVHADDLGHEVLARGGAGYALVVAEFGREILDDKGEIDRKALGALVFGYPERL
DRLNAIVHPAVIRREEELLAEFAARHPDGIAVVEAAILVETGSYKRFDKLVLVTCREEQQVERAMRREGASEGDVRARIG
RQMPLAEKRKFADFVIDTSGEKADTLRQTRAVYDTLRRIES
>Mature_201_residues
MLKVGLTGGIGCGKSFVGEALADYGCLVVHADDLGHEVLARGGAGYALVVAEFGREILDDKGEIDRKALGALVFGYPERL
DRLNAIVHPAVIRREEELLAEFAARHPDGIAVVEAAILVETGSYKRFDKLVLVTCREEQQVERAMRREGASEGDVRARIG
RQMPLAEKRKFADFVIDTSGEKADTLRQTRAVYDTLRRIES

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=201, Percent_Identity=36.318407960199, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI191252795, Length=201, Percent_Identity=36.318407960199, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI110227607, Length=197, Percent_Identity=32.994923857868, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI110227605, Length=197, Percent_Identity=32.994923857868, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI110227603, Length=197, Percent_Identity=32.994923857868, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI110227601, Length=197, Percent_Identity=32.994923857868, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI205277394, Length=197, Percent_Identity=32.994923857868, Blast_Score=97, Evalue=8e-21,
Organism=Escherichia coli, GI1786292, Length=177, Percent_Identity=32.2033898305085, Blast_Score=92, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17554944, Length=192, Percent_Identity=36.4583333333333, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25143409, Length=198, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320402, Length=199, Percent_Identity=33.6683417085427, Blast_Score=96, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24644728, Length=198, Percent_Identity=32.3232323232323, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24658602, Length=199, Percent_Identity=31.6582914572864, Blast_Score=100, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22084; Mature: 22084

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS01294 COAE ; PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKVGLTGGIGCGKSFVGEALADYGCLVVHADDLGHEVLARGGAGYALVVAEFGREILDD
CEEECCCCCCCCCHHHHHHHHHHCCEEEEEECHHHHHHHHCCCCCCCHHHHHHHHHHHCC
KGEIDRKALGALVFGYPERLDRLNAIVHPAVIRREEELLAEFAARHPDGIAVVEAAILVE
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEE
TGSYKRFDKLVLVTCREEQQVERAMRREGASEGDVRARIGRQMPLAEKRKFADFVIDTSG
CCCCHHHHHEEEEEECCHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHEEECCC
EKADTLRQTRAVYDTLRRIES
CHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKVGLTGGIGCGKSFVGEALADYGCLVVHADDLGHEVLARGGAGYALVVAEFGREILDD
CEEECCCCCCCCCHHHHHHHHHHCCEEEEEECHHHHHHHHCCCCCCCHHHHHHHHHHHCC
KGEIDRKALGALVFGYPERLDRLNAIVHPAVIRREEELLAEFAARHPDGIAVVEAAILVE
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEE
TGSYKRFDKLVLVTCREEQQVERAMRREGASEGDVRARIGRQMPLAEKRKFADFVIDTSG
CCCCHHHHHEEEEEECCHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHEEECCC
EKADTLRQTRAVYDTLRRIES
CHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]