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The map label for this gene is macB [H]

Identifier: 116623666

GI number: 116623666

Start: 5791142

End: 5793547

Strand: Direct

Name: macB [H]

Synonym: Acid_4578

Alternate gene names: 116623666

Gene position: 5791142-5793547 (Clockwise)

Preceding gene: 116623665

Following gene: 116623668

Centisome position: 58.11

GC content: 65.71

Gene sequence:

>2406_bases
ATGGTTTCCCAGGACGTCCGCTACGCGCTGCGCACGCTGCGGCGCAACGCCGGGTTCACCACCTTTGCGATCCTGATCGT
CGGGCTCGGCATCGGCGCCAGCTCTACCGTTTTCAGCGTAGTGAACGCGCTGCTGATTCGTCCCCTGCCCTTTCGCGACC
CCGGCCGCCTGGTGTGGATGGCGAATAAGGATACCAGCGGACTCTCAGGCCAAACCACGCAGGTCGGGTACTTTCTCGAT
CTCAAGGCCGGAAACCAGTCGTTCTCCGACATCGCGGCTTACTTCGCGTTTTATGGCGTCGGCGACAACAAACTCACCGG
CGATGGCGAGCCGGAGCGCCTCAGCGGAGTACCCGTCTCGCAGAACTTCTTCCCGCTGCTGGGCGTGCAGCCGCAACTCG
GCCGCCTGTTCAACGACGAGGAATGCAAGTGGCACGGCCCTAAGGCGGTCTTGTTGAGCCACGGGCTGTGGGAGCGGCGC
TTCGCCTCCGATCCCCACATCGTGGGCCGGCCGCTGACGCTCAACGATGAGCCAGTCACGGTGATCGGCGTGATGCCCGC
GTCGTTCGATTTTCCGGCGGTATTCGCGCCCGGCAGCCACATCGATCTCTACTTCCCCTTCCCGATGACCGCGGAGACCA
ACCGTTGGGGCAATACGCTGGCGATGGTCGGCAGGCTCAAGCCGGGAGTGTCGGTGGCCAGCGCGCAGGCCGAAGTCACC
GCGCTCGGCGTACAACTCACGCGCGCGCACCGGGAGCGCAACGATTTTGAGGGCCGCCTCTCACCGCTGGCGGAGCATGT
GTCCGGACGGATCCGGCCCGCCCTGCTGGTATTGACGTTCGCGGTCTGCGTAGTGATGCTGATTGTCTGCGCGAACCTCT
CGAACCTGCTGCTGGCTCGCACCGCTTCGCGTCAAAAGGAAATCGCGGTCCGCATGGCGCTTGGCGCGGGGCGGCTGCGG
CTGATGCGCCAGATGTTGACCGAGAGCCTGGTGCTCTCCGGCGGCGGCGCGCTGCTCGGGCTGCTGCTCGCAATCGGAGG
GACGCGGGCGCTTTCGCATTTGGAATCGATCGGCATACCGCTGCTGCACAACGTGCAGATCGACATGACGGCGCTCGGCT
TCATCCTGGTGATGGCAGTGGCCACCGGACTCGTCTTTGGACTGGCGCCGGCGCTGCACATTCCCGCCGCCGCCGTACAC
GACGCCCTGAAGGAGACCGGCCGTGGTTCCACGGAAGGCCACGGAAGAGCGTGGATTCGCAGCGCGCTGGTAATTTCCGA
AGTGGCCTTCGCGTGCGTCCTTCTGGTCGGTGCCGGACTCCTGATCCGCAGCTTTCTGCGGGTGCTGGATGTGAACATGG
GCTTCCGTCCGGAGCATGCCGCCGCCATACGCGTAGATCCCGACAAGGGCTATTCGACGCAGGCGCAGCAGAACGTGTAC
TTCGATGAGGTGCTTCGCCGCGTCAGGGAAGTGCCGGGCATCGAAGCCGCCGGGATTTCCGACGCGCTGCCGCTGGGGCG
CAACCGCACCTGGGGCGCTCCGGCCAAAGGCCAGGTGTATCCGAAGGGCAAATTCCCGATCGCGTACGTTCGCGTGGTCA
GCGATGGCTACATCAGGGCAATGGGGATTCCGCTGCGCTCGGGCCGCGATCTTTCGCCGCAGGACACGCCCACGAGCGAA
CCGGTGATTATGGTCAACGAAACCTTGGCGCGCACCTTGTGGCCCGGCGAGAATGCGATCGGGAAGATCATGCGGGTCAA
CGGGGAACGGCGCGTGGTTGGTGTGGTGGGCGATGTTCGTCATCTCGCGCTTGAAGAGGGCTCGGGCATGGAAATGTACC
TGCCGCTGCGCCAGGGCAGCGACTGGTCGTCGGCGGACCTGGTGGTGCGGACGACGCTGCCTCCGGCGGAGCTCGCACCG
GCAATCCGCGCCGCGCTGAAGCCGATACAGCCGAATCTGCCGGGCAATGATTTCCGCCCGATCCAGCAACTGGTAGACAA
GGCCGTCTCGCCGCGGCGTCTTGTAGTGCTGCTGCTCGGCGGCTTCGCGCTGTTCGCGCTGGTTCTGGCGTCGCTCGGAA
TTTATGGCGTGATCTCCTACTCGGTGGGCCAGCGGACGCAGGAGATCGGGATCCGCATGGCCTTGGGCGCGTCGCCGGCC
GACCTGCAAATGCGCATCATGATGCAGACCCTCGGGCTCGCCGCCATCGGAATGGTGCTGGGAGTGAGCGCCTCCTGGGT
GCTGGCGCGGGCGCTCGGCGGCATACTCTTCGGCGTAACGGCGGGCGACCCCGTGACGTTCGTCGGCATGCCGCTCGTGC
TAATTGCGGTCGCGGCGCTGGCCGGATATCTTCCCGCCCGCCGCGCCTCGCGGATCGACCCGATGCTGGCGCTGCGCAGT
TCGTAA

Upstream 100 bases:

>100_bases
CGATGGCAAACAATGCGTCGCGATCGCCGCGGGCCGCGTACTCTATGTCTTTTCCCTGTAGGGACTAACCGACCGGAAAC
GGTTACGTCAAACTAAAATC

Downstream 100 bases:

>100_bases
AAAAGATTCTGGCCACGAATGGACACGGCGCGGTATAGCCGCAACCAAATCACCGGTGGGTCCTGATTGTCGCGGAAGAA
AGAACAAATGGGCCACGGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 801; Mature: 801

Protein sequence:

>801_residues
MVSQDVRYALRTLRRNAGFTTFAILIVGLGIGASSTVFSVVNALLIRPLPFRDPGRLVWMANKDTSGLSGQTTQVGYFLD
LKAGNQSFSDIAAYFAFYGVGDNKLTGDGEPERLSGVPVSQNFFPLLGVQPQLGRLFNDEECKWHGPKAVLLSHGLWERR
FASDPHIVGRPLTLNDEPVTVIGVMPASFDFPAVFAPGSHIDLYFPFPMTAETNRWGNTLAMVGRLKPGVSVASAQAEVT
ALGVQLTRAHRERNDFEGRLSPLAEHVSGRIRPALLVLTFAVCVVMLIVCANLSNLLLARTASRQKEIAVRMALGAGRLR
LMRQMLTESLVLSGGGALLGLLLAIGGTRALSHLESIGIPLLHNVQIDMTALGFILVMAVATGLVFGLAPALHIPAAAVH
DALKETGRGSTEGHGRAWIRSALVISEVAFACVLLVGAGLLIRSFLRVLDVNMGFRPEHAAAIRVDPDKGYSTQAQQNVY
FDEVLRRVREVPGIEAAGISDALPLGRNRTWGAPAKGQVYPKGKFPIAYVRVVSDGYIRAMGIPLRSGRDLSPQDTPTSE
PVIMVNETLARTLWPGENAIGKIMRVNGERRVVGVVGDVRHLALEEGSGMEMYLPLRQGSDWSSADLVVRTTLPPAELAP
AIRAALKPIQPNLPGNDFRPIQQLVDKAVSPRRLVVLLLGGFALFALVLASLGIYGVISYSVGQRTQEIGIRMALGASPA
DLQMRIMMQTLGLAAIGMVLGVSASWVLARALGGILFGVTAGDPVTFVGMPLVLIAVAALAGYLPARRASRIDPMLALRS
S

Sequences:

>Translated_801_residues
MVSQDVRYALRTLRRNAGFTTFAILIVGLGIGASSTVFSVVNALLIRPLPFRDPGRLVWMANKDTSGLSGQTTQVGYFLD
LKAGNQSFSDIAAYFAFYGVGDNKLTGDGEPERLSGVPVSQNFFPLLGVQPQLGRLFNDEECKWHGPKAVLLSHGLWERR
FASDPHIVGRPLTLNDEPVTVIGVMPASFDFPAVFAPGSHIDLYFPFPMTAETNRWGNTLAMVGRLKPGVSVASAQAEVT
ALGVQLTRAHRERNDFEGRLSPLAEHVSGRIRPALLVLTFAVCVVMLIVCANLSNLLLARTASRQKEIAVRMALGAGRLR
LMRQMLTESLVLSGGGALLGLLLAIGGTRALSHLESIGIPLLHNVQIDMTALGFILVMAVATGLVFGLAPALHIPAAAVH
DALKETGRGSTEGHGRAWIRSALVISEVAFACVLLVGAGLLIRSFLRVLDVNMGFRPEHAAAIRVDPDKGYSTQAQQNVY
FDEVLRRVREVPGIEAAGISDALPLGRNRTWGAPAKGQVYPKGKFPIAYVRVVSDGYIRAMGIPLRSGRDLSPQDTPTSE
PVIMVNETLARTLWPGENAIGKIMRVNGERRVVGVVGDVRHLALEEGSGMEMYLPLRQGSDWSSADLVVRTTLPPAELAP
AIRAALKPIQPNLPGNDFRPIQQLVDKAVSPRRLVVLLLGGFALFALVLASLGIYGVISYSVGQRTQEIGIRMALGASPA
DLQMRIMMQTLGLAAIGMVLGVSASWVLARALGGILFGVTAGDPVTFVGMPLVLIAVAALAGYLPARRASRIDPMLALRS
S
>Mature_801_residues
MVSQDVRYALRTLRRNAGFTTFAILIVGLGIGASSTVFSVVNALLIRPLPFRDPGRLVWMANKDTSGLSGQTTQVGYFLD
LKAGNQSFSDIAAYFAFYGVGDNKLTGDGEPERLSGVPVSQNFFPLLGVQPQLGRLFNDEECKWHGPKAVLLSHGLWERR
FASDPHIVGRPLTLNDEPVTVIGVMPASFDFPAVFAPGSHIDLYFPFPMTAETNRWGNTLAMVGRLKPGVSVASAQAEVT
ALGVQLTRAHRERNDFEGRLSPLAEHVSGRIRPALLVLTFAVCVVMLIVCANLSNLLLARTASRQKEIAVRMALGAGRLR
LMRQMLTESLVLSGGGALLGLLLAIGGTRALSHLESIGIPLLHNVQIDMTALGFILVMAVATGLVFGLAPALHIPAAAVH
DALKETGRGSTEGHGRAWIRSALVISEVAFACVLLVGAGLLIRSFLRVLDVNMGFRPEHAAAIRVDPDKGYSTQAQQNVY
FDEVLRRVREVPGIEAAGISDALPLGRNRTWGAPAKGQVYPKGKFPIAYVRVVSDGYIRAMGIPLRSGRDLSPQDTPTSE
PVIMVNETLARTLWPGENAIGKIMRVNGERRVVGVVGDVRHLALEEGSGMEMYLPLRQGSDWSSADLVVRTTLPPAELAP
AIRAALKPIQPNLPGNDFRPIQQLVDKAVSPRRLVVLLLGGFALFALVLASLGIYGVISYSVGQRTQEIGIRMALGASPA
DLQMRIMMQTLGLAAIGMVLGVSASWVLARALGGILFGVTAGDPVTFVGMPLVLIAVAALAGYLPARRASRIDPMLALRS
S

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=354, Percent_Identity=24.8587570621469, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 85846; Mature: 85846

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSQDVRYALRTLRRNAGFTTFAILIVGLGIGASSTVFSVVNALLIRPLPFRDPGRLVWM
CCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEE
ANKDTSGLSGQTTQVGYFLDLKAGNQSFSDIAAYFAFYGVGDNKLTGDGEPERLSGVPVS
ECCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCC
QNFFPLLGVQPQLGRLFNDEECKWHGPKAVLLSHGLWERRFASDPHIVGRPLTLNDEPVT
CCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEECCCCHHHHCCCCCCEECCCEECCCCCEE
VIGVMPASFDFPAVFAPGSHIDLYFPFPMTAETNRWGNTLAMVGRLKPGVSVASAQAEVT
EEEEECCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCHHCCHHHH
ALGVQLTRAHRERNDFEGRLSPLAEHVSGRIRPALLVLTFAVCVVMLIVCANLSNLLLAR
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
TASRQKEIAVRMALGAGRLRLMRQMLTESLVLSGGGALLGLLLAIGGTRALSHLESIGIP
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCC
LLHNVQIDMTALGFILVMAVATGLVFGLAPALHIPAAAVHDALKETGRGSTEGHGRAWIR
EEECCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHH
SALVISEVAFACVLLVGAGLLIRSFLRVLDVNMGFRPEHAAAIRVDPDKGYSTQAQQNVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHCCCC
FDEVLRRVREVPGIEAAGISDALPLGRNRTWGAPAKGQVYPKGKFPIAYVRVVSDGYIRA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCEEE
MGIPLRSGRDLSPQDTPTSEPVIMVNETLARTLWPGENAIGKIMRVNGERRVVGVVGDVR
ECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHCCCCCHHHHHHEEECCCEEEEEEHHHHH
HLALEEGSGMEMYLPLRQGSDWSSADLVVRTTLPPAELAPAIRAALKPIQPNLPGNDFRP
HHHHCCCCCCEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHH
IQQLVDKAVSPRRLVVLLLGGFALFALVLASLGIYGVISYSVGQRTQEIGIRMALGASPA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHEEEHHHCCHHHHCCEEEEECCCCH
DLQMRIMMQTLGLAAIGMVLGVSASWVLARALGGILFGVTAGDPVTFVGMPLVLIAVAAL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHH
AGYLPARRASRIDPMLALRSS
HHHCCHHHHHCCCHHHHCCCC
>Mature Secondary Structure
MVSQDVRYALRTLRRNAGFTTFAILIVGLGIGASSTVFSVVNALLIRPLPFRDPGRLVWM
CCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEE
ANKDTSGLSGQTTQVGYFLDLKAGNQSFSDIAAYFAFYGVGDNKLTGDGEPERLSGVPVS
ECCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCC
QNFFPLLGVQPQLGRLFNDEECKWHGPKAVLLSHGLWERRFASDPHIVGRPLTLNDEPVT
CCCCCCCCCCHHHHHCCCCCCCCCCCCCEEEECCCCHHHHCCCCCCEECCCEECCCCCEE
VIGVMPASFDFPAVFAPGSHIDLYFPFPMTAETNRWGNTLAMVGRLKPGVSVASAQAEVT
EEEEECCCCCCCEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCHHCCHHHH
ALGVQLTRAHRERNDFEGRLSPLAEHVSGRIRPALLVLTFAVCVVMLIVCANLSNLLLAR
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
TASRQKEIAVRMALGAGRLRLMRQMLTESLVLSGGGALLGLLLAIGGTRALSHLESIGIP
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCC
LLHNVQIDMTALGFILVMAVATGLVFGLAPALHIPAAAVHDALKETGRGSTEGHGRAWIR
EEECCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHH
SALVISEVAFACVLLVGAGLLIRSFLRVLDVNMGFRPEHAAAIRVDPDKGYSTQAQQNVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCHHCCCC
FDEVLRRVREVPGIEAAGISDALPLGRNRTWGAPAKGQVYPKGKFPIAYVRVVSDGYIRA
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCEEE
MGIPLRSGRDLSPQDTPTSEPVIMVNETLARTLWPGENAIGKIMRVNGERRVVGVVGDVR
ECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHCCCCCHHHHHHEEECCCEEEEEEHHHHH
HLALEEGSGMEMYLPLRQGSDWSSADLVVRTTLPPAELAPAIRAALKPIQPNLPGNDFRP
HHHHCCCCCCEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHH
IQQLVDKAVSPRRLVVLLLGGFALFALVLASLGIYGVISYSVGQRTQEIGIRMALGASPA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHEEEHHHCCHHHHCCEEEEECCCCH
DLQMRIMMQTLGLAAIGMVLGVSASWVLARALGGILFGVTAGDPVTFVGMPLVLIAVAAL
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHH
AGYLPARRASRIDPMLALRSS
HHHCCHHHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA