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The map label for this gene is qheDH [H]

Identifier: 116623665

GI number: 116623665

Start: 5789540

End: 5791102

Strand: Direct

Name: qheDH [H]

Synonym: Acid_4577

Alternate gene names: 116623665

Gene position: 5789540-5791102 (Clockwise)

Preceding gene: 116623664

Following gene: 116623666

Centisome position: 58.1

GC content: 65.32

Gene sequence:

>1563_bases
ATGAGATGGTGCGCGCTTCTGCTCTGCTGCTGCCCGGCTTGGGGCCAGGTCTCCTACGAGCGCCTCGTGAACGCGGCGAA
GGAGCCCGGCAACTGGCTCACCTACTCCGGCAACCTACAGGGCCATCGCTACTCACCGCTCGTGGAGCTTACGCCTGCGA
ACGCGGGGAACCTGCGCGTGAAGTGGGCCTATCAGCTGGAATCGCGCGGCGAGGTATCGCCGATCGTTGTCGATGGCGTG
ATGTACATTACCGGCCCCAACACGGCGGCAGCGTTGGACGCACGCACCGGCCGCCGTCTGTGGAGCTGGTCGCGCCCGAT
TCCGAAGGATTACCAGAATATTGGATTCGGCCGGGTGAACCGCGGCCCTGCCATTCTCGATGACCTGATCTTCGTCGCCA
CGCTGGATTGCTACCTGGTCGCGCTCGATGCCAGGAGCGGCCAGGAACGCTGGTCATCCCAGGTGGCGGATTACAAGCCG
GGATACAGCATGACGCTGGCGCCGCTCGCGATCCGCGGCAAGGTGTTGGTCGGCGTGAGCGGAGGCGAGACCGGCATTCG
CGGCTTCGTGGATGCATACGATGCAAAGACCGGCGCGCGCGCATGGCGCTTCCACACCATTCCCGGGCCGGGCGAGCCGG
GAAACGATACCTGGCCCGGCGACAGCTGGAGGACCGGCGGCGGCTCCACCTGGGTCACCGGCGCCTACGATCCGGAGACC
AACCTTGTCTATTGGGGCATCGGCAATCCGGGGCCCGACTGGAATCCCGATTCGCGCCGCGGCGACAATCTGTATACCTG
CTCGCTGGTGGCGCTCGATGGCGACACCGGGAAATTGAAGTGGCATTTCCAGTTCACGCCCAACGATTCGCACGATTGGG
ATTCCACGCACGTACCGGTGCTCTTCGACGCCGATGTCCGCGGCACGCGCCGGAAGCTGGTGGCGGTGGCCAATCGCAAC
GCCTTCTACTACGTGCTGGACCGCGGCAGCGGCGAATTCCTGGAAGGCCGGGCCTACGCCAGACAAACGTGGGCCAAGGG
GCTGGACGATCGCGGCCGCCCGATCGTGATCCCCGGCACCGAGCCCAGCGAGGCGGGCACGCTGGTCTGGCCCAACCTCA
ACGGCGCGACGGTGTGGTTCAGCCCATCGTATAGCCCGCGCGAAGGTCTGCTCTATGTGGCCGTGCGCGAGATCGCGTCG
ATTTACTTCAAACGCAAAGCCGAGTACAAGCCCGGCACCTTCTTCGCAGGCGGCGGCGAGGCCAGTGCGCCGGGGCCGCC
CTCGGGCGCGATCCGCGCGCTGGAAGCCGCCACCGGCAAGATGCGGTGGGAGTTCAAGATGCACACCGCACCGTGGGCCG
GCGTTCTCTCTACCGCGGGCGGTCTCGTATTCTCCGGCTCCGACGAGGGCAACTTCTTCGCGCTCGACGCCAAGACTGGT
AAGCCGCTGTGGGATTTCCAAACCGGCGGCGGAATTGCCGCCAATCCGATTTCCTTCAATATCGATGGCAAACAATGCGT
CGCGATCGCCGCGGGCCGCGTACTCTATGTCTTTTCCCTGTAG

Upstream 100 bases:

>100_bases
GCTTGGAGGGCGCGACTCCAATGCCACCGTATGAGGGCAAGATCCCGGGAAACGCGCTTGACGATCTTGTGGCCTACCTG
GCCGGCCTGAAGGGGAAATT

Downstream 100 bases:

>100_bases
GGACTAACCGACCGGAAACGGTTACGTCAAACTAAAATCATGGTTTCCCAGGACGTCCGCTACGCGCTGCGCACGCTGCG
GCGCAACGCCGGGTTCACCA

Product: pyrrolo-quinoline quinone

Products: NA

Alternate protein names: QH-EDH1; Quinohaemoprotein ethanol dehydrogenase type I [H]

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MRWCALLLCCCPAWGQVSYERLVNAAKEPGNWLTYSGNLQGHRYSPLVELTPANAGNLRVKWAYQLESRGEVSPIVVDGV
MYITGPNTAAALDARTGRRLWSWSRPIPKDYQNIGFGRVNRGPAILDDLIFVATLDCYLVALDARSGQERWSSQVADYKP
GYSMTLAPLAIRGKVLVGVSGGETGIRGFVDAYDAKTGARAWRFHTIPGPGEPGNDTWPGDSWRTGGGSTWVTGAYDPET
NLVYWGIGNPGPDWNPDSRRGDNLYTCSLVALDGDTGKLKWHFQFTPNDSHDWDSTHVPVLFDADVRGTRRKLVAVANRN
AFYYVLDRGSGEFLEGRAYARQTWAKGLDDRGRPIVIPGTEPSEAGTLVWPNLNGATVWFSPSYSPREGLLYVAVREIAS
IYFKRKAEYKPGTFFAGGGEASAPGPPSGAIRALEAATGKMRWEFKMHTAPWAGVLSTAGGLVFSGSDEGNFFALDAKTG
KPLWDFQTGGGIAANPISFNIDGKQCVAIAAGRVLYVFSL

Sequences:

>Translated_520_residues
MRWCALLLCCCPAWGQVSYERLVNAAKEPGNWLTYSGNLQGHRYSPLVELTPANAGNLRVKWAYQLESRGEVSPIVVDGV
MYITGPNTAAALDARTGRRLWSWSRPIPKDYQNIGFGRVNRGPAILDDLIFVATLDCYLVALDARSGQERWSSQVADYKP
GYSMTLAPLAIRGKVLVGVSGGETGIRGFVDAYDAKTGARAWRFHTIPGPGEPGNDTWPGDSWRTGGGSTWVTGAYDPET
NLVYWGIGNPGPDWNPDSRRGDNLYTCSLVALDGDTGKLKWHFQFTPNDSHDWDSTHVPVLFDADVRGTRRKLVAVANRN
AFYYVLDRGSGEFLEGRAYARQTWAKGLDDRGRPIVIPGTEPSEAGTLVWPNLNGATVWFSPSYSPREGLLYVAVREIAS
IYFKRKAEYKPGTFFAGGGEASAPGPPSGAIRALEAATGKMRWEFKMHTAPWAGVLSTAGGLVFSGSDEGNFFALDAKTG
KPLWDFQTGGGIAANPISFNIDGKQCVAIAAGRVLYVFSL
>Mature_520_residues
MRWCALLLCCCPAWGQVSYERLVNAAKEPGNWLTYSGNLQGHRYSPLVELTPANAGNLRVKWAYQLESRGEVSPIVVDGV
MYITGPNTAAALDARTGRRLWSWSRPIPKDYQNIGFGRVNRGPAILDDLIFVATLDCYLVALDARSGQERWSSQVADYKP
GYSMTLAPLAIRGKVLVGVSGGETGIRGFVDAYDAKTGARAWRFHTIPGPGEPGNDTWPGDSWRTGGGSTWVTGAYDPET
NLVYWGIGNPGPDWNPDSRRGDNLYTCSLVALDGDTGKLKWHFQFTPNDSHDWDSTHVPVLFDADVRGTRRKLVAVANRN
AFYYVLDRGSGEFLEGRAYARQTWAKGLDDRGRPIVIPGTEPSEAGTLVWPNLNGATVWFSPSYSPREGLLYVAVREIAS
IYFKRKAEYKPGTFFAGGGEASAPGPPSGAIRALEAATGKMRWEFKMHTAPWAGVLSTAGGLVFSGSDEGNFFALDAKTG
KPLWDFQTGGGIAANPISFNIDGKQCVAIAAGRVLYVFSL

Specific function: Catalyzes the dye-linked oxidation of primary alcohols to the corresponding aldehydes and the (subsequent) oxidation of the aldehydes to carboxylic acids [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=616, Percent_Identity=24.6753246753247, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009056
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.98.1 [H]

Molecular weight: Translated: 56641; Mature: 56641

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWCALLLCCCPAWGQVSYERLVNAAKEPGNWLTYSGNLQGHRYSPLVELTPANAGNLRV
CHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCEECCEEEECCCCCCCEEE
KWAYQLESRGEVSPIVVDGVMYITGPNTAAALDARTGRRLWSWSRPIPKDYQNIGFGRVN
EEEEEECCCCCCCEEEEEEEEEEECCCCCEEEECCCCCHHHCCCCCCCHHHHHCCCCCCC
RGPAILDDLIFVATLDCYLVALDARSGQERWSSQVADYKPGYSMTLAPLAIRGKVLVGVS
CCCHHHHHHHHHHEEEEEEEEEECCCCHHHHHHHCCCCCCCCCEEEEEEEEECEEEEEEC
GGETGIRGFVDAYDAKTGARAWRFHTIPGPGEPGNDTWPGDSWRTGGGSTWVTGAYDPET
CCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCEECCCCCEEEEEEECCCC
NLVYWGIGNPGPDWNPDSRRGDNLYTCSLVALDGDTGKLKWHFQFTPNDSHDWDSTHVPV
CEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCE
LFDADVRGTRRKLVAVANRNAFYYVLDRGSGEFLEGRAYARQTWAKGLDDRGRPIVIPGT
EEECCCCCCCEEEEEEECCCEEEEEEECCCCCEECCHHHHHHHHHCCCCCCCCEEEECCC
EPSEAGTLVWPNLNGATVWFSPSYSPREGLLYVAVREIASIYFKRKAEYKPGTFFAGGGE
CCCCCCEEEECCCCCCEEEECCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCEEEECCCC
ASAPGPPSGAIRALEAATGKMRWEFKMHTAPWAGVLSTAGGLVFSGSDEGNFFALDAKTG
CCCCCCCHHHHHEEHHCCCCEEEEEEECCCCCHHHHHCCCCEEEECCCCCCEEEEECCCC
KPLWDFQTGGGIAANPISFNIDGKQCVAIAAGRVLYVFSL
CCEEEEECCCCEEECCEEEECCCCEEEEEECCCEEEEEEC
>Mature Secondary Structure
MRWCALLLCCCPAWGQVSYERLVNAAKEPGNWLTYSGNLQGHRYSPLVELTPANAGNLRV
CHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCEECCEEEECCCCCCCEEE
KWAYQLESRGEVSPIVVDGVMYITGPNTAAALDARTGRRLWSWSRPIPKDYQNIGFGRVN
EEEEEECCCCCCCEEEEEEEEEEECCCCCEEEECCCCCHHHCCCCCCCHHHHHCCCCCCC
RGPAILDDLIFVATLDCYLVALDARSGQERWSSQVADYKPGYSMTLAPLAIRGKVLVGVS
CCCHHHHHHHHHHEEEEEEEEEECCCCHHHHHHHCCCCCCCCCEEEEEEEEECEEEEEEC
GGETGIRGFVDAYDAKTGARAWRFHTIPGPGEPGNDTWPGDSWRTGGGSTWVTGAYDPET
CCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCEECCCCCEEEEEEECCCC
NLVYWGIGNPGPDWNPDSRRGDNLYTCSLVALDGDTGKLKWHFQFTPNDSHDWDSTHVPV
CEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEECCCCEEEEEEEECCCCCCCCCCCCCCE
LFDADVRGTRRKLVAVANRNAFYYVLDRGSGEFLEGRAYARQTWAKGLDDRGRPIVIPGT
EEECCCCCCCEEEEEEECCCEEEEEEECCCCCEECCHHHHHHHHHCCCCCCCCEEEECCC
EPSEAGTLVWPNLNGATVWFSPSYSPREGLLYVAVREIASIYFKRKAEYKPGTFFAGGGE
CCCCCCEEEECCCCCCEEEECCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCEEEECCCC
ASAPGPPSGAIRALEAATGKMRWEFKMHTAPWAGVLSTAGGLVFSGSDEGNFFALDAKTG
CCCCCCCHHHHHEEHHCCCCEEEEEEECCCCCHHHHHCCCCEEEECCCCCCEEEEECCCC
KPLWDFQTGGGIAANPISFNIDGKQCVAIAAGRVLYVFSL
CCEEEEECCCCEEECCEEEECCCCEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8654419; 7601151; 3521592; 11679760; 11714714 [H]