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The map label for this gene is macB1 [H]

Identifier: 116623529

GI number: 116623529

Start: 5617868

End: 5620339

Strand: Direct

Name: macB1 [H]

Synonym: Acid_4439

Alternate gene names: 116623529

Gene position: 5617868-5620339 (Clockwise)

Preceding gene: 116623528

Following gene: 116623531

Centisome position: 56.37

GC content: 62.94

Gene sequence:

>2472_bases
ATGCCGGCCTGGCTCGAAGAAAGATGGCGAGACCTGCGCTTCGCCGTACGGTCCCTGGCTCGAACACCTGGGTTCACCTC
CATCGCGCTCCTGGTGATTGCGGCCGGTATCGGCGTAAATACCGCTGTGTTTTCGGTGGTGAATGCCGTGTTTCTCAAGC
CCCTGGCCTATCCCGATCCGCGGACGCTGGTGCAACTGGTGACCACCGGGAATCGGGGGCCGATTCCGGTCGCGAACATC
CCCGAGTACAGCGTCTGGAGACAGCAATCCGCTGTCTTCCGGCAGGTGGCGGCCTATGATTGGGGCGGAGCCGGCATAAA
CCTCAACGGCGGAGAGCATCCGGAGCAGGTACGCGGCATGCATGTGACCAGCGAATATTTCGCGCTGTTCGGCGCCCCGT
TGGCGGCGGGACGCACGTTCACGGCGGCGGAAGATCGCCCCAATGCCGGTCACTTTGTCGTGTTGAGTTACGGACTGTGG
CAGAGGCGCTTCGGAGGGAACCGTGAAATCGTCGGCTCTACCATCCAGGTGGACGACCAGTCGTGGCTGGTTGTCGGCGT
ATTAGGTCGCGGCTTCGCCAGCGACACCCCCACGGATCTATGGATTCCCTTTCAGTTTGATCTCACGTCGCGAGAGATGT
TTCGCAACTTCAACGTGGCGGCGCGCCTGATACCGGGCGTCACCCCCGCCCAGGCAAATGCGCAGCTCGCGCTGGCCGCT
GACCAGTTCCGCCGCGCCTATGGCAGCAACGCTCTGCCGCCCCAGGGCGGCTTTGGCGCAGTGCCGCTGCAGGATGCTCT
GGTAGGCGATATCCGGTTCCCACTCATGATTTTGCTCGGAGCTGTGGTGTTCGTGCTTCTCATCGCCTGCGCTAATGTGG
CCAACCTTCTGCTGGCGCGAGCCTCGGTCCGAAAACGCGAATTTGCAACGCGTGCCGCTCTGGGCGCCGGGCGTGGACAA
ATCATTCGACAACTGCTGACCGAGAGCCTTGTGCTCTCCTCTTTCGGCGGCCTGCTGGGCCTGGCCATCGGGTTCAGCGG
CGTGCGTCTGCTGTTGAGCGTCAGTAACGGCAACATTCCTCGAATCGGAGAGAATGGCTCGGCTGTGGGACTCGATTATC
GGGTCTTGCTGTTCACCGTGGCCGTGTCGCTGCTGACCGGCATGCTCTTCGGATTGGCGCCCGCCCTCTCCGCCTCGCGC
GCCGATCTCATCACCGCTCTCAAGGGTAGTTCCAGCCATTCCGGCACGGTCCTTCGGCATTCCAGGTTTCGCTCCCTGCT
GGTGGTAAGCGAGTTTGCACTGGCTCTGGTTCTTGTCATCGGAGCCGCTCTACTCATCCGGACTTTTCTCAAGTTGGAGG
ACGTCAATCCCGGTTTCACCACCGATAACGTTCTCAGCGCGTCGATGTCGATGACGGGTCGCCGCTTTCAGGCCACGGGA
CCTGTGGCCCAGGTCGTTCGCGATGGCCGCGAGCGCCTGATGGCCGTCCCCGGAGTACTTGACGTGGGCGTAAGCAACTG
CCTGCCGCTGCAGGGCTGTTTCGGCATGGGCTTTGACGTCTTGGGACGGGGGGCGGGAGAGACGCCGGCCAATGGCGTCG
CCGGCTATTTCTCCATCTCGTGGAGCTATTTCTCGGCCTTGGAAATACCTTTGTTGCGCGGCCGCGCTTTCACCGCGATG
GATGATGGCGCCGCGCCCGGAGTCGTCATCATCAACCAGGCGATGGCCCGGCGGTATTGGCCCCACGGCGACCCGATGAA
AGACCGGATTCGAATCGGAGCGGGTGGTCCGGCGTTTGCCGAGCCGCCCCGCAAGATCATTGCCGTCGTGGGGGACACAC
GCGATGCTGGCGTCAGTCGCGATCCTTTTCCGACGATGTACATTCCAATCGCGCAGATGCCGGACGCGCAGACTGCGCTC
AATTCACGGGTTGCACCGCTCTGGTGGATCGTGCGCAGCCGCATGAATCCCTATACCTTGCGGGCTCCCATCGAAGCTGC
GCTGCGTGATGCCAGCGGAGGCATGCCGGTCGCCCGTGTCCGGACTATGGCGGAGGTCGCGGCCCGCGACACAGCGCGCC
AGCGTTTCAATATGCTCTTCCTCACTATCTTTGGAGCAGCCGGCCTGCTGATGGCCGCCATCGGTATTTACGGTGTCATC
GCCTATTCCATCCAGCTCCGCACTCGGGAGCTCGGCGTGCGTATGGCGCTCGGGGCCGACCCTTCGAAGCTCCGCAATGC
GGTTATCGGTCAGGGCATGATGCTGGCCGCCGCCGGTCTGGTCCTGGGCCTCGGTGGGTCTTTCTGGCTCACTCGCTTGC
TGGCCAGCTTCCTCTTTGGTGTCACAGCCAGGGACCCGATCGCATTTGTGGTGACGCCGCTGGTTCTCGGCGCAACCGCG
CTTTTCGCGGTTTGGCTTCCGGCGCAGAGAGTCACTCGCGTCGATCCGATGACTGCGCTTCGGCTCGAATAG

Upstream 100 bases:

>100_bases
TTGAATTCACCGTGACTTTGAGGGACGACACACATGCCGAAATCCACCCGGCAGGAGCACCGGCAAACATGAAGCCGATA
CCGGCCCGAAAGGTTCGCTA

Downstream 100 bases:

>100_bases
CGGAGAGCGTTCGTAGGAAAGCCGGAGTCAACTCTGCCGTATGAAGTCCGCGCTAAGGCGCCGATAGGAATCTGAGGATC
TCCTGCATCAACCGCTCACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 823; Mature: 822

Protein sequence:

>823_residues
MPAWLEERWRDLRFAVRSLARTPGFTSIALLVIAAGIGVNTAVFSVVNAVFLKPLAYPDPRTLVQLVTTGNRGPIPVANI
PEYSVWRQQSAVFRQVAAYDWGGAGINLNGGEHPEQVRGMHVTSEYFALFGAPLAAGRTFTAAEDRPNAGHFVVLSYGLW
QRRFGGNREIVGSTIQVDDQSWLVVGVLGRGFASDTPTDLWIPFQFDLTSREMFRNFNVAARLIPGVTPAQANAQLALAA
DQFRRAYGSNALPPQGGFGAVPLQDALVGDIRFPLMILLGAVVFVLLIACANVANLLLARASVRKREFATRAALGAGRGQ
IIRQLLTESLVLSSFGGLLGLAIGFSGVRLLLSVSNGNIPRIGENGSAVGLDYRVLLFTVAVSLLTGMLFGLAPALSASR
ADLITALKGSSSHSGTVLRHSRFRSLLVVSEFALALVLVIGAALLIRTFLKLEDVNPGFTTDNVLSASMSMTGRRFQATG
PVAQVVRDGRERLMAVPGVLDVGVSNCLPLQGCFGMGFDVLGRGAGETPANGVAGYFSISWSYFSALEIPLLRGRAFTAM
DDGAAPGVVIINQAMARRYWPHGDPMKDRIRIGAGGPAFAEPPRKIIAVVGDTRDAGVSRDPFPTMYIPIAQMPDAQTAL
NSRVAPLWWIVRSRMNPYTLRAPIEAALRDASGGMPVARVRTMAEVAARDTARQRFNMLFLTIFGAAGLLMAAIGIYGVI
AYSIQLRTRELGVRMALGADPSKLRNAVIGQGMMLAAAGLVLGLGGSFWLTRLLASFLFGVTARDPIAFVVTPLVLGATA
LFAVWLPAQRVTRVDPMTALRLE

Sequences:

>Translated_823_residues
MPAWLEERWRDLRFAVRSLARTPGFTSIALLVIAAGIGVNTAVFSVVNAVFLKPLAYPDPRTLVQLVTTGNRGPIPVANI
PEYSVWRQQSAVFRQVAAYDWGGAGINLNGGEHPEQVRGMHVTSEYFALFGAPLAAGRTFTAAEDRPNAGHFVVLSYGLW
QRRFGGNREIVGSTIQVDDQSWLVVGVLGRGFASDTPTDLWIPFQFDLTSREMFRNFNVAARLIPGVTPAQANAQLALAA
DQFRRAYGSNALPPQGGFGAVPLQDALVGDIRFPLMILLGAVVFVLLIACANVANLLLARASVRKREFATRAALGAGRGQ
IIRQLLTESLVLSSFGGLLGLAIGFSGVRLLLSVSNGNIPRIGENGSAVGLDYRVLLFTVAVSLLTGMLFGLAPALSASR
ADLITALKGSSSHSGTVLRHSRFRSLLVVSEFALALVLVIGAALLIRTFLKLEDVNPGFTTDNVLSASMSMTGRRFQATG
PVAQVVRDGRERLMAVPGVLDVGVSNCLPLQGCFGMGFDVLGRGAGETPANGVAGYFSISWSYFSALEIPLLRGRAFTAM
DDGAAPGVVIINQAMARRYWPHGDPMKDRIRIGAGGPAFAEPPRKIIAVVGDTRDAGVSRDPFPTMYIPIAQMPDAQTAL
NSRVAPLWWIVRSRMNPYTLRAPIEAALRDASGGMPVARVRTMAEVAARDTARQRFNMLFLTIFGAAGLLMAAIGIYGVI
AYSIQLRTRELGVRMALGADPSKLRNAVIGQGMMLAAAGLVLGLGGSFWLTRLLASFLFGVTARDPIAFVVTPLVLGATA
LFAVWLPAQRVTRVDPMTALRLE
>Mature_822_residues
PAWLEERWRDLRFAVRSLARTPGFTSIALLVIAAGIGVNTAVFSVVNAVFLKPLAYPDPRTLVQLVTTGNRGPIPVANIP
EYSVWRQQSAVFRQVAAYDWGGAGINLNGGEHPEQVRGMHVTSEYFALFGAPLAAGRTFTAAEDRPNAGHFVVLSYGLWQ
RRFGGNREIVGSTIQVDDQSWLVVGVLGRGFASDTPTDLWIPFQFDLTSREMFRNFNVAARLIPGVTPAQANAQLALAAD
QFRRAYGSNALPPQGGFGAVPLQDALVGDIRFPLMILLGAVVFVLLIACANVANLLLARASVRKREFATRAALGAGRGQI
IRQLLTESLVLSSFGGLLGLAIGFSGVRLLLSVSNGNIPRIGENGSAVGLDYRVLLFTVAVSLLTGMLFGLAPALSASRA
DLITALKGSSSHSGTVLRHSRFRSLLVVSEFALALVLVIGAALLIRTFLKLEDVNPGFTTDNVLSASMSMTGRRFQATGP
VAQVVRDGRERLMAVPGVLDVGVSNCLPLQGCFGMGFDVLGRGAGETPANGVAGYFSISWSYFSALEIPLLRGRAFTAMD
DGAAPGVVIINQAMARRYWPHGDPMKDRIRIGAGGPAFAEPPRKIIAVVGDTRDAGVSRDPFPTMYIPIAQMPDAQTALN
SRVAPLWWIVRSRMNPYTLRAPIEAALRDASGGMPVARVRTMAEVAARDTARQRFNMLFLTIFGAAGLLMAAIGIYGVIA
YSIQLRTRELGVRMALGADPSKLRNAVIGQGMMLAAAGLVLGLGGSFWLTRLLASFLFGVTARDPIAFVVTPLVLGATAL
FAVWLPAQRVTRVDPMTALRLE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=295, Percent_Identity=25.4237288135593, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 88069; Mature: 87938

Theoretical pI: Translated: 11.01; Mature: 11.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAWLEERWRDLRFAVRSLARTPGFTSIALLVIAAGIGVNTAVFSVVNAVFLKPLAYPDP
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCH
RTLVQLVTTGNRGPIPVANIPEYSVWRQQSAVFRQVAAYDWGGAGINLNGGEHPEQVRGM
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHCCC
HVTSEYFALFGAPLAAGRTFTAAEDRPNAGHFVVLSYGLWQRRFGGNREIVGSTIQVDDQ
EEHHHHHHHHCCHHHCCCEEECCCCCCCCCCEEEEECCHHHHHCCCCCEEECCEEEECCC
SWLVVGVLGRGFASDTPTDLWIPFQFDLTSREMFRNFNVAARLIPGVTPAQANAQLALAA
CEEEEEEECCCCCCCCCCCEEEEEEECCCHHHHHHCCCHHHHHCCCCCCCCCCCEEEEEH
DQFRRAYGSNALPPQGGFGAVPLQDALVGDIRFPLMILLGAVVFVLLIACANVANLLLAR
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASVRKREFATRAALGAGRGQIIRQLLTESLVLSSFGGLLGLAIGFSGVRLLLSVSNGNIP
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCC
RIGENGSAVGLDYRVLLFTVAVSLLTGMLFGLAPALSASRADLITALKGSSSHSGTVLRH
CCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHH
SRFRSLLVVSEFALALVLVIGAALLIRTFLKLEDVNPGFTTDNVLSASMSMTGRRFQATG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEECCC
PVAQVVRDGRERLMAVPGVLDVGVSNCLPLQGCFGMGFDVLGRGAGETPANGVAGYFSIS
HHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHCCCHHHHCCCCCCCCCCCCEEEEEEE
WSYFSALEIPLLRGRAFTAMDDGAAPGVVIINQAMARRYWPHGDPMKDRIRIGAGGPAFA
HHHHHHHCCHHCCCCEEEECCCCCCCCEEEECHHHHHHCCCCCCCHHHCEEECCCCCCCC
EPPRKIIAVVGDTRDAGVSRDPFPTMYIPIAQMPDAQTALNSRVAPLWWIVRSRMNPYTL
CCCHHEEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHCCCCEEE
RAPIEAALRDASGGMPVARVRTMAEVAARDTARQRFNMLFLTIFGAAGLLMAAIGIYGVI
ECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYSIQLRTRELGVRMALGADPSKLRNAVIGQGMMLAAAGLVLGLGGSFWLTRLLASFLFG
HHHEEEEHHHHCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHC
VTARDPIAFVVTPLVLGATALFAVWLPAQRVTRVDPMTALRLE
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEECC
>Mature Secondary Structure 
PAWLEERWRDLRFAVRSLARTPGFTSIALLVIAAGIGVNTAVFSVVNAVFLKPLAYPDP
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCH
RTLVQLVTTGNRGPIPVANIPEYSVWRQQSAVFRQVAAYDWGGAGINLNGGEHPEQVRGM
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHCCC
HVTSEYFALFGAPLAAGRTFTAAEDRPNAGHFVVLSYGLWQRRFGGNREIVGSTIQVDDQ
EEHHHHHHHHCCHHHCCCEEECCCCCCCCCCEEEEECCHHHHHCCCCCEEECCEEEECCC
SWLVVGVLGRGFASDTPTDLWIPFQFDLTSREMFRNFNVAARLIPGVTPAQANAQLALAA
CEEEEEEECCCCCCCCCCCEEEEEEECCCHHHHHHCCCHHHHHCCCCCCCCCCCEEEEEH
DQFRRAYGSNALPPQGGFGAVPLQDALVGDIRFPLMILLGAVVFVLLIACANVANLLLAR
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASVRKREFATRAALGAGRGQIIRQLLTESLVLSSFGGLLGLAIGFSGVRLLLSVSNGNIP
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCC
RIGENGSAVGLDYRVLLFTVAVSLLTGMLFGLAPALSASRADLITALKGSSSHSGTVLRH
CCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHH
SRFRSLLVVSEFALALVLVIGAALLIRTFLKLEDVNPGFTTDNVLSASMSMTGRRFQATG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEECCC
PVAQVVRDGRERLMAVPGVLDVGVSNCLPLQGCFGMGFDVLGRGAGETPANGVAGYFSIS
HHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHCCCHHHHCCCCCCCCCCCCEEEEEEE
WSYFSALEIPLLRGRAFTAMDDGAAPGVVIINQAMARRYWPHGDPMKDRIRIGAGGPAFA
HHHHHHHCCHHCCCCEEEECCCCCCCCEEEECHHHHHHCCCCCCCHHHCEEECCCCCCCC
EPPRKIIAVVGDTRDAGVSRDPFPTMYIPIAQMPDAQTALNSRVAPLWWIVRSRMNPYTL
CCCHHEEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHCCCCEEE
RAPIEAALRDASGGMPVARVRTMAEVAARDTARQRFNMLFLTIFGAAGLLMAAIGIYGVI
ECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYSIQLRTRELGVRMALGADPSKLRNAVIGQGMMLAAAGLVLGLGGSFWLTRLLASFLFG
HHHEEEEHHHHCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHC
VTARDPIAFVVTPLVLGATALFAVWLPAQRVTRVDPMTALRLE
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA