Click here to switch to the map view.

The map label for this gene is 116623480

Identifier: 116623480

GI number: 116623480

Start: 5553468

End: 5554700

Strand: Direct

Name: 116623480

Synonym: Acid_4390

Alternate gene names: NA

Gene position: 5553468-5554700 (Clockwise)

Preceding gene: 116623479

Following gene: 116623481

Centisome position: 55.73

GC content: 63.02

Gene sequence:

>1233_bases
ATGATTCACATGTCACACTTCCGCCTTGCCACCGCCGCGCTCGCCGCCGCCACCCTCATCCACGCGCAGGCCCCCGGCCG
CCAGAAGCGCACCGTCACCGACGACGAAGTGCAGCGAGTCCACAAGAGCGCTCTCGTCCTCGATGCCCACAACGATGTCA
CCAGCGCCACTGTCGCCGGCATGGACATCGGCAAATCCAACCCCGACCACATGACCGATCTCCCACGCATGAAGGCTGGC
GGCATGGGCGCCCAGATCTTCGCCGTCTACGTTGCCGCCAGCTACGCCGAGGGCAATCACGCTGCCAACCGCGCGCTGCA
GATGATCGACACCGTCCGCCACGACATCATCGCCCGCTACCCTAACGACTTCCTCTTCGCGGGCAGCGTCGCCGATATCC
GCCGCGCCCAAAAGGAGCACAAGATCGCCGCCCTGCTCGGCATCGAAGGCGGCCACGCCATCGAAGATTCTCCCCGCCTC
CTCCGCGACTTCTACGATCTCGGCGTCCGCTACATGACGCTCACCCACACCAACAGCAACCACTGGGCCGATTCCTCCGG
CGACCTCAACAAACCCAACAACGGCCTCTCCCCGCTCGGCAAGGAAATTGTCGCGGAGATGAACCGAATCGGCATGATCG
TCGATATCTCGCACGTCTCCGACAAGACCTTCTTTGACGCGCTCGAAGTCAGCAAGGCGCCCATCTTCGCCTCACACTCC
TCCTGCCGCGCACTCTCCCCCGCCCCCCGCAACATGACCGACGAGATGATCACCGCCCTCGGCAAAAAGCACGGAGTCGT
GCAAATCAACTTCGCCTGCGACTTCCTCAACCCCGAGGTCTTCGCCGAAAACGAAAAGAACCGTGACAAGCTCGTGACAC
TCCGCGCCGAGCTCATCAAGAAATACGCCAACGATCCCGATGGCCTCCAGAAGGCTTTCAAGGAGGCAAGCGCCGCCGCC
GGCGCTTCGACGAAGCGCGCCACGCTAGCCGACGTCGTCAAGCACATCAACCACGTCGTCCAACTCGCCGGCATCGATTC
CGTCGGCCTCGGCAGCGATTTCGACGGCATCGACTGCGCCCCCATCGGCCTCGACAGCGTCGATAAGTGGCCCAACCTCA
CCCGGGCTCTTCTCGAGGAAGGCTACACCGCCGCCGAAGTCCGCAAGATCTACGGGGAAAACACTCTCCGTCTCCTCTCC
GATGTCGAGCGTGTCGCGAAGGGATCGCACTAA

Upstream 100 bases:

>100_bases
CGATTGCATCGGTAACCAGCAGAAGCTCACGCTCTACCGCGACTACGGGCCGCCGATAGAAATCGGCCGCTTCCTGCTGT
TTACGAATACGCCATACTGA

Downstream 100 bases:

>100_bases
GACATTTCTCGCAGAGCCGCAGAGCCGCGGAGTCACGCAAAGAAGACACTTAAATAGGCGGCAGCGAACTCGGGCCGCGA
TCTCAGGGAGGTCAATCCCT

Product: membrane dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MIHMSHFRLATAALAAATLIHAQAPGRQKRTVTDDEVQRVHKSALVLDAHNDVTSATVAGMDIGKSNPDHMTDLPRMKAG
GMGAQIFAVYVAASYAEGNHAANRALQMIDTVRHDIIARYPNDFLFAGSVADIRRAQKEHKIAALLGIEGGHAIEDSPRL
LRDFYDLGVRYMTLTHTNSNHWADSSGDLNKPNNGLSPLGKEIVAEMNRIGMIVDISHVSDKTFFDALEVSKAPIFASHS
SCRALSPAPRNMTDEMITALGKKHGVVQINFACDFLNPEVFAENEKNRDKLVTLRAELIKKYANDPDGLQKAFKEASAAA
GASTKRATLADVVKHINHVVQLAGIDSVGLGSDFDGIDCAPIGLDSVDKWPNLTRALLEEGYTAAEVRKIYGENTLRLLS
DVERVAKGSH

Sequences:

>Translated_410_residues
MIHMSHFRLATAALAAATLIHAQAPGRQKRTVTDDEVQRVHKSALVLDAHNDVTSATVAGMDIGKSNPDHMTDLPRMKAG
GMGAQIFAVYVAASYAEGNHAANRALQMIDTVRHDIIARYPNDFLFAGSVADIRRAQKEHKIAALLGIEGGHAIEDSPRL
LRDFYDLGVRYMTLTHTNSNHWADSSGDLNKPNNGLSPLGKEIVAEMNRIGMIVDISHVSDKTFFDALEVSKAPIFASHS
SCRALSPAPRNMTDEMITALGKKHGVVQINFACDFLNPEVFAENEKNRDKLVTLRAELIKKYANDPDGLQKAFKEASAAA
GASTKRATLADVVKHINHVVQLAGIDSVGLGSDFDGIDCAPIGLDSVDKWPNLTRALLEEGYTAAEVRKIYGENTLRLLS
DVERVAKGSH
>Mature_410_residues
MIHMSHFRLATAALAAATLIHAQAPGRQKRTVTDDEVQRVHKSALVLDAHNDVTSATVAGMDIGKSNPDHMTDLPRMKAG
GMGAQIFAVYVAASYAEGNHAANRALQMIDTVRHDIIARYPNDFLFAGSVADIRRAQKEHKIAALLGIEGGHAIEDSPRL
LRDFYDLGVRYMTLTHTNSNHWADSSGDLNKPNNGLSPLGKEIVAEMNRIGMIVDISHVSDKTFFDALEVSKAPIFASHS
SCRALSPAPRNMTDEMITALGKKHGVVQINFACDFLNPEVFAENEKNRDKLVTLRAELIKKYANDPDGLQKAFKEASAAA
GASTKRATLADVVKHINHVVQLAGIDSVGLGSDFDGIDCAPIGLDSVDKWPNLTRALLEEGYTAAEVRKIYGENTLRLLS
DVERVAKGSH

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI189458885, Length=384, Percent_Identity=31.5104166666667, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI4758190, Length=384, Percent_Identity=31.5104166666667, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI11641269, Length=372, Percent_Identity=32.258064516129, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI193211608, Length=382, Percent_Identity=28.7958115183246, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI193211610, Length=382, Percent_Identity=28.7958115183246, Blast_Score=159, Evalue=6e-39,
Organism=Drosophila melanogaster, GI221475880, Length=349, Percent_Identity=37.5358166189112, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI281362638, Length=340, Percent_Identity=35.8823529411765, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI281362636, Length=340, Percent_Identity=35.8823529411765, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI161083233, Length=337, Percent_Identity=35.3115727002967, Blast_Score=198, Evalue=5e-51,
Organism=Drosophila melanogaster, GI21356391, Length=278, Percent_Identity=24.1007194244604, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 44520; Mature: 44520

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00869 RENAL_DIPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHMSHFRLATAALAAATLIHAQAPGRQKRTVTDDEVQRVHKSALVLDAHNDVTSATVAG
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCCCHHHEEC
MDIGKSNPDHMTDLPRMKAGGMGAQIFAVYVAASYAEGNHAANRALQMIDTVRHDIIARY
CCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
PNDFLFAGSVADIRRAQKEHKIAALLGIEGGHAIEDSPRLLRDFYDLGVRYMTLTHTNSN
CCCEEEECCHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHCCEEEEEEEECCCC
HWADSSGDLNKPNNGLSPLGKEIVAEMNRIGMIVDISHVSDKTFFDALEVSKAPIFASHS
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHCCCCEEECCC
SCRALSPAPRNMTDEMITALGKKHGVVQINFACDFLNPEVFAENEKNRDKLVTLRAELIK
CCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCHHCCCCCCCHHHHHHHHHHHHH
KYANDPDGLQKAFKEASAAAGASTKRATLADVVKHINHVVQLAGIDSVGLGSDFDGIDCA
HHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PIGLDSVDKWPNLTRALLEEGYTAAEVRKIYGENTLRLLSDVERVAKGSH
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIHMSHFRLATAALAAATLIHAQAPGRQKRTVTDDEVQRVHKSALVLDAHNDVTSATVAG
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCCCHHHEEC
MDIGKSNPDHMTDLPRMKAGGMGAQIFAVYVAASYAEGNHAANRALQMIDTVRHDIIARY
CCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
PNDFLFAGSVADIRRAQKEHKIAALLGIEGGHAIEDSPRLLRDFYDLGVRYMTLTHTNSN
CCCEEEECCHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHCCEEEEEEEECCCC
HWADSSGDLNKPNNGLSPLGKEIVAEMNRIGMIVDISHVSDKTFFDALEVSKAPIFASHS
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHCCCCEEECCC
SCRALSPAPRNMTDEMITALGKKHGVVQINFACDFLNPEVFAENEKNRDKLVTLRAELIK
CCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCHHCCCCCCCHHHHHHHHHHHHH
KYANDPDGLQKAFKEASAAAGASTKRATLADVVKHINHVVQLAGIDSVGLGSDFDGIDCA
HHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PIGLDSVDKWPNLTRALLEEGYTAAEVRKIYGENTLRLLSDVERVAKGSH
CCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]